Zonegran Tablet 10'S
Key Information
Generic Name
Generic Name Zonisamide 100 mg
Manufacturer
Eisai Pharmaceuticals India Pvt Ltd
Variant
10 Tablet(s) in a Strip
Country of Origin
India
Detailed Information
Introduction
ZONEGRAN TABLET contains Zonisamide which belongs to a group of medicines called Antiepileptics. It is used to manage partial seizures (affecting one part of the brain), which may or may not be followed by secondary generalisation (a seizure affecting all of the brain). Seizures are bursts of electrical activity that affect the functioning of the brain. During management with ZONEGRAN TABLET, your doctor might regularly monitor your weight and your child’s blood bicarbonate levels and kidneys. Drink sufficient water to keep yourself hydrated during ZONEGRAN TABLET management. Before taking ZONEGRAN TABLET, inform your doctor if you have any liver, eye or kidney problems, are underweight or are staying in a place where the weather is warm. ZONEGRAN TABLET should be used in pregnant and breastfeeding women only if your doctor finds it necessary. ZONEGRAN TABLET is not recommended for use in children (aged less than 6 years or underweight). The most common
Uses
OF ZONEGRAN TABLETZONEGRAN TABLET is used to manage: Partial seizures, which may or may not be followed by secondary generalisation
How It Works
ZONEGRAN TABLET works by supressing electrical activities of the brain by altering the synthesis, release and degradation of certain nerve chemicals (glutamate, gamma-aminobutyric acid (GABA), dopamine, serotonin and acetylcholine).
Directions for Use
Always take ZONEGRAN TABLET as advised by your physician. Swallow with a glass of water and do not crush or chew it. The exact dose of ZONEGRAN TABLET will be decided by your physician depending upon your age, disease severity and body weight. Do not stop taking ZONEGRAN TABLET unless your doctor advises you to stop.
Side Effects
ZONEGRAN TABLET include agitation, irritability, confusion, depression, etc. Consult your doctor if any of the symptoms deteriorate. USES OF ZONEGRAN TABLETZONEGRAN TABLET is used to manage: Partial seizures, which may or may not be followed by secondary generalisation HOW ZONEGRAN TABLET WORKSZONEGRAN TABLET works by supressing electrical activities of the brain by altering the synthesis, release and degradation of certain nerve chemicals (glutamate, gamma-aminobutyric acid (GABA), dopamine, serotonin and acetylcholine). DIRECTIONS FOR USEAlways take ZONEGRAN TABLET as advised by your physician. Swallow with a glass of water and do not crush or chew it. The exact dose of ZONEGRAN TABLET will be decided by your physician depending upon your age, disease severity and body weight. Do not stop taking ZONEGRAN TABLET unless your doctor advises you to stop. SIDE EFFECTS OF ZONEGRAN TABLETCOMMON agitation, irritability, confusion, depression disturbed muscle coordination, dizziness, poor memory, sleepiness, double vision loss of appetite, reduced blood levels of bicarbonate sleeping difficulty, unusual thoughts, feeling anxious or emotional disturbed thoughts, loss of concentration, speech problem, abnormal skin sensation, shakiness, involuntary movement of the eyes kidney stones skin rashes, itching, allergic reactions, tiredness, flu-like symptoms, fever, hair loss ecchymosis (a small bruise caused due to blood leakage from broken blood vessels in the skin) loss of weight, nausea, indigestion, stomach pains, diarrhoea, constipation swelling of the feet and legs pneumonia, dehydration, decreased sweating (in children 6-17 years old) UNCOMMON anger, aggression vomiting gall bladder inflammation, gallstones urinary stones lung infection/inflammation, urinary tract infections low blood potassium levels, convulsions/seizures abnormal liver enzymes (in children 6-17 years old) RARE lupus erythematosus (an autoimmune disease causing scaly red patches on the skin, particularly on the face) irregular heartbeat, heart failure, clot in lungs inflammation of bile duct, food pipe or intestines, vomiting blood, cholestatic jaundice, stool incontinence, mouth ulceration low red blood cells or platelets, purple spot due to bleeding into the skin low blood sugar or sodium levels uncontrollable, jerky or reduced muscle movement, facial paralysis, increased physical sensitivity, upward eyeball movements breathlessness, coughing up blood light sensitivity, eye inflammation increased protein in urine, involuntary urination, bladder pain or calculus breast enlargement in men, breast inflammation, heavy menstrual bleeding Stop taking ZONEGRAN TABLET and contact your doctor immediately if you experience any of the following side effects: severe allergic reaction (difficulty breathing, swelling of face, lips or tongue, severe skin rash) signs of overheating (high body temperature, little or no sweating, rapid heartbeat and breathing, muscle cramps, confusion) thoughts of self-harm unusual muscle breakdown (muscle pain or weakness) kidney stones (sudden pain in back or stomach, pain on urinating, blood in urine) vision problems such as eye pain or blurred vision unexplained skin rash, leading to a more severe skin rash or peeling blood disorder (swollen glands, tiredness, sore throat, fever, easy bruising) increased blood acid levels (headache, feeling sleepy, shortness of breath, loss of appetite)
Warnings & Precautions
& PRECAUTIONSPREGNANCYZONEGRAN TABLET should be used in pregnant women only if clearly necessary. Women of childbearing potential should take proper contraception till 1 month after stopping this> management. Consult your doctor for advice. BREASTFEEDINGZONEGRAN TABLET should be used in breastfeeding women only if clearly necessary. Consult your doctor for advice. DRIVING AND USING MACHINESDo not drive or operate any machines if you feel sleepy or if your concentration or ability to react/respond is affected after taking ZONEGRAN TABLET. KIDNEYZONEGRAN TABLET should be used with caution in patients having kidney stones or other kidney problems. Consult your doctor for advice. LIVERZONEGRAN TABLET should be used with caution in patients having liver problems. Consult your doctor for advice. ALLERGYDo not take ZONEGRAN TABLET if you are allergic to Zonisamide, other sulphonamide medicines (Ex. sulphonamide antibiotics, thiazide diuretics, sulfonylurea antidiabetes medicines) or any of the other ingredients of this medicine. OTHERSBefore taking ZONEGRAN TABLET tell your doctor if you: have eye problems like glaucoma are staying in a place where the weather is warm are underweight or have lost a lot of weight Use in Paediatrics: ZONEGRAN TABLET is not recommended for use in children (aged less than 6 years, underweight or having a small appetite). ZONEGRAN TABLET should be used with caution in children (aged less than 12 years weighing below 20kg). Consult your child’s doctor for advice. Use in Geriatrics: ZONEGRAN TABLET should be used with caution in elderly patients. Consult your doctor for advice.
Drug Interactions
SA. Drug-Drug Interactions: Before taking ZONEGRAN TABLET, inform your doctor if you are taking any of the following medicines: phenytoin, carbamazepine, phenobarbitone, valproate, topiramate (medicines used to manage seizures) acetazolamide (used to manage eye problems like glaucoma) rifampicin (used to manage bacterial infections) digoxin, quinidine (used to manage irregular heartbeat and other heart problems) Overdosage: If you or anyone else accidentally take too much of ZONEGRAN TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose are sleepiness, loss of consciousness, nausea, stomach pain, muscle twitches, eye movement, a slower heartbeat or reduced breathing. SYNOPSIS Drug : Zonisamide Pharmacological Category : Antiepileptic Therapeutic Indication : Seizures Dosage Forms : Tablet, Capsule MORE INFORMATION Keep ZONEGRAN TABLET out of sight of children Store ZONEGRAN TABLET at room temperature
Article Information
Written By
DETAILS Written By Dr. Jeenal Rajani
Medical Content Writer
Reviewed By
Dr. Sankara Babu Gorle
Medical Expert
Last Updated
14 Dec 2022