ZONALTA 8mg Tablet 7's
Key Information
Generic Name
Generic Name Endoxifen 8 mg
Manufacturer
Intas Pharmaceuticals Ltd
Variant
7 Tablet(s) in a Strip
Country of Origin
India
Detailed Information
Introduction
ZONALTA 8MG TABLET contains Endoxifen, which belongs to the group of medicines called protein kinase C inhibitors. It is used in the management of acute manic episodes with or without mixed features of bipolar I disorder. Bipolar I disorder is a psychiatric condition that ca
Uses
changes in mood (from low to high), activity levels, energy and the ability to perform everyday tasks. ZONALTA 8MG TABLET is not recommended for use in patients with deep vein thrombosis or pulmonary embolism. ZONALTA 8MG TABLET should be used with caution in patients with irregular menses (in women), uterus or endometrial cancer, breast cancer, endometriosis, uterine fibroids, ovarian cysts and cataracts. Avoid consuming grapefruit juice while taking ZONALTA 8MG TABLET. ZONALTA 8MG TABLET is not recommended for use in pregnant women and females of reproductive potential should use effective contraception for 2 months after the last dose of ZONALTA 8MG TABLET. Do not breastfeed the baby during the management and for 3 months after taking the last dose of ZONALTA 8MG TABLET. The safety and effectiveness of ZONALTA 8MG TABLET in children and elderly patients have not been established. The most common
How It Works
ZONALTA 8MG TABLET works by inhibiting protein kinase C activity (which is increased in the manic phase of patients with bipolar disorder) in the nervous system and subsequently helps to balance certain chemicals in the brain such as glutamate, serotonin, norepinephrine and dopamine that control mood.
Directions for Use
Take ZONALTA 8MG TABLET as advised by your doctor. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you.
Side Effects
taking ZONALTA 8MG TABLET are insomnia, headache, nausea, vomiting, indigestion, decreased appetite, delusions and worsening of mania. Contact your physician if any of your symptoms get worse or persist. USES OF ZONALTA 8MG TABLET Manage manic episodes with or without mixed features of bipolar disorder HOW ZONALTA 8MG TABLET WORKSZONALTA 8MG TABLET works by inhibiting protein kinase C activity (which is increased in the manic phase of patients with bipolar disorder) in the nervous system and subsequently helps to balance certain chemicals in the brain such as glutamate, serotonin, norepinephrine and dopamine that control mood. DIRECTIONS FOR USETake ZONALTA 8MG TABLET as advised by your doctor. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you. SIDE EFFECTS OF ZONALTA 8MG TABLETCOMMON Insomnia Headache Nausea Vomiting Indigestion Decreased appetite Delusion Worsening of mania Stop taking ZONALTA 8MG TABLET and contact your physician immediately if you experience any of the following side effects: Signs and symptoms of thromboembolism such as symptoms of leg swelling, tenderness and unexplained shortness of breath
Warnings & Precautions
& PRECAUTIONSPREGNANCYContraindicatedZONALTA 8MG TABLET is not suitable for use in pregnant women and females of reproductive potential should use effective contraception for 2 months after the last dose of ZONALTA 8MG TABLET. Contact your doctor before taking it. BREASTFEEDINGContraindicatedDo not breastfeed during management and for 3 months after the last dose of ZONALTA 8MG TABLET. Contact your doctor before taking ZONALTA 8MG TABLET. DRIVING AND USING MACHINESUse with CautionEndoxifen is unlikely to impair the ability of patients to drive or operate machinery. However, caution should be exercised. Consult your doctor for advice. KIDNEYConsult your doctorThe safety and effectiveness of ZONALTA 8MG TABLET in patients with kidney disease are not established. Contact your doctor before taking ZONALTA 8MG TABLET. LIVERConsult your doctorThe safety and effectiveness of ZONALTA 8MG TABLET in patients with liver disease are not established. Contact your doctor before taking ZONALTA 8MG TABLET. ALLERGYContraindicatedDo not take ZONALTA 8MG TABLET if you are allergic to Endoxifen, tamoxifen or other ingredients in this medicine. USE IN PEDIATRICSConsult your doctorThe safety and effectiveness of ZONALTA 8MG TABLET in children have not been established. Contact your doctor before taking it. USE IN GERIATRICSConsult your doctorThe safety and effectiveness of ZONALTA 8MG TABLET in elderly patients aged 65 years or above have not been established. Contact your doctor before taking it. OTHERSZONALTA 8MG TABLET is not recommended for use if you have: Deep vein thrombosis Pulmonary embolism Before taking ZONALTA 8MG TABLET, inform your doctor if you have: Irregular menses (in women) Uterus or endometrial cancer Breast cancer Endometriosis Uterine fibroids Ovarian cysts Cataracts or eye diseases Low white blood cells (leukopenia) and platelets (thrombocytopenia) Hypercalcemia (increased calcium levels)
Drug Interactions
SA. Drug-Drug interactions: Before taking ZONALTA 8MG TABLET, inform your doctor if you are taking any of the following medicine: Coumarin-type Anticoagulants Ex. warfarin (a medicine used to manage or prevent blood clots) B. Drug-Food interaction: Avoid consuming grapefruit juice while taking ZONALTA 8MG TABLET Overdosage: If you or anyone else accidentally take too much of ZONALTA 8MG TABLET, consult your doctor immediately or visit the nearby hospital. SYNOPSIS Drug : Endoxifen Pharmacological Category : Protein kinase C inhibitor Therapeutic Indication : Manic, Mixed features of Bipolar I disorder Dosage Forms : Tablet MORE INFORMATION Keep ZONALTA 8MG TABLET out of the sight and reach of children Store ZONALTA 8MG TABLET at room temperature
Frequently Asked Questions
Common questions and answers about ZONALTA 8mg Tablet 7's.
What is ZONALTA 8MG TABLET used for?
ZONALTA 8MG TABLET contains Endoxifen. It is used for the acute management of manic episodes with or without mixed features of Bipolar I disorder.
What is Bipolar disorder Type- 1?
Bipolar I disorder is a mental condition that causes changes in mood (low to high), activity levels, energy and the ability to perform everyday tasks.
What are the side effects of taking ZONALTA 8MG TABLET?
The most common side effects of taking ZONALTA 8MG TABLET are insomnia, headache, nausea, vomiting, indigestion, decreased appetite, delusions and worsening of mania. Contact your physician if the symptoms worsen.
Can I use ZONALTA 8MG TABLET in pregnancy?
No, ZONALTA 8MG TABLET is not suitable for use in pregnant women and females of reproductive potential should use effective contraception for 2 months after the last dose of ZONALTA 8MG TABLET. Contact your doctor before taking it.
How does ZONALTA 8MG TABLET work?
ZONALTA 8MG TABLET works by inhibiting protein kinase C activity (which is increased in the manic phase of patients with bipolar disorder) in the nervous system and subsequently helps to manage certain chemicals in the brain such as glutamate, serotonin, norepinephrine and dopamine that controls mood.
Article Information
Written By
DETAILS Written By Dr. Dhivakaran R
Medical Content Writer
Reviewed By
Dr. Sankara Babu Gorle
Medical Expert
Last Updated
11 Mar 2023