Zendol 50mg Capsule 10'S
Key Information
Generic Name
Generic Name Danazol 50 mg
Manufacturer
Serum Institute Of India Ltd
Variant
10 Capsule(s) in a Strip
Country of Origin
India
Detailed Information
Introduction
INTRODUCTION ABOUT ZENDOL 50MG CAPSULEZENDOL 50MG CAPSULE contains Danazol which belongs to the group of medicines called Androgens. It is used to manage endometriosis, severe cyclical mastalgia (breast pain associated with hormonal variations), breast cysts, dysfunctional uterine bleeding (bleeding from vagina other than that of menstrual cycle), symptomatic gynecomastia, preoperative thinning of endometrium and hereditary angioneurotic edema (painless swelling under the skin). Endometriosis is defined as an illness where some of the tissues that line the womb are found elsewhere in the body. Gynecomastia refers to an increase in the amount of breast gland tissue in males, due to an imbalance of hormones estrogen and testosterone. Prior to the management, your doctor may want you to take several blood tests to understand your existing condition. Avoid consumption of alcohol during management with ZENDOL 50MG CAPSULE, as it may cause nausea or breathlessness. Before taking ZENDOL 50MG CAPSULE, inform your doctor if you have hormonal cancer, blood clots, heart, liver or kidney problems or porphyria. ZENDOL 50MG CAPSULE is not recommended for use among pregnant or breastfeeding women, therefore consult your doctor before taking it. Safety and effectiveness of ZENDOL 50MG CAPSULE in paediatric and elderly patients have not been established. The most common
Uses
OF ZENDOL 50MG CAPSULEManage: endometriosis severe cyclical mastalgia breast cysts dysfunctional uterine bleeding symptomatic gynecomastia preoperative thinning of endometrium hereditary angioneurotic edema
How It Works
ZENDOL 50MG CAPSULE works by suppressing the secretion of gonadotropins (a group hormones that stimulate the activity of the gonads) in both men and women, leading to inhibition of testicular/ovarian function. In addition, it suppresses gonadal function directly by inhibiting the enzymes involved in steroid hormone synthesis.
Directions for Use
Take ZENDOL 50MG CAPSULE as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition. Do not stop taking ZENDOL 50MG CAPSULE unless your doctor advice you to stop.
Side Effects
taking ZENDOL 50MG CAPSULE are weight gain, bloating, nausea, vomiting, lethargy and headache. Consult your doctor if any of the side effects worsen. USES OF ZENDOL 50MG CAPSULEManage: endometriosis severe cyclical mastalgia breast cysts dysfunctional uterine bleeding symptomatic gynecomastia preoperative thinning of endometrium hereditary angioneurotic edema HOW ZENDOL 50MG CAPSULE WORKSZENDOL 50MG CAPSULE works by suppressing the secretion of gonadotropins (a group hormones that stimulate the activity of the gonads) in both men and women, leading to inhibition of testicular/ovarian function. In addition, it suppresses gonadal function directly by inhibiting the enzymes involved in steroid hormone synthesis. DIRECTIONS FOR USETake ZENDOL 50MG CAPSULE as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition. Do not stop taking ZENDOL 50MG CAPSULE unless your doctor advice you to stop. SIDE EFFECTS OF ZENDOL 50MG CAPSULECOMMON weight gain bloating nausea, vomiting gastroenteritis joint pain, muscle spasm lethargy headache depression RAREStop taking ZENDOL 50MG CAPSULE and contact your doctor immediately if you experience any of the following side effects: allergic reaction (rash, difficulty swallowing or breathing, swelling of your lips, face, throat or tongue) signs of heart attack (pain or tightness in the chest, jaw or arm) severe headache and vomiting clitoris becomes larger blurred vision, problems with eyesight, difficulty wearing contact lenses liver problems that may cause the eyes or skin to go yellow (jaundice) pain in the liver or liver failure may cause a swollen abdomen, mental disorientation and confusion pain when moving arms or legs (this may be due to a blood clot) feeling weak together with numb arms or legs which you may not be able to move (stroke) bruising more easily, getting more infections than usual (signs of a blood problem)
Warnings & Precautions
& PRECAUTIONSPREGNANCYZENDOL 50MG CAPSULE is not recommended for use in pregnant women. Consult your doctor before taking it. BREASTFEEDINGZENDOL 50MG CAPSULE is not recommended for use in breastfeeding women. Consult your doctor before taking it. DRIVING AND USING MACHINESZENDOL 50MG CAPSULE has no or negligible influence on the ability to drive and use machines. ALCOHOLAvoid consumption of alcohol while taking ZENDOL 50MG CAPSULE as it can cause nausea or breathlessness. KIDNEYZENDOL 50MG CAPSULE is not recommended for use in patients with impaired kidney function. Consult your doctor before taking ZENDOL 50MG CAPSULE. LIVERZENDOL 50MG CAPSULE is not recommended for use in patients with impaired liver function. Consult your doctor before taking ZENDOL 50MG CAPSULE. ALLERGYDo not take ZENDOL 50MG CAPSULE if you are allergic to Danazol or any other ingredients of this medicine. HEART DISEASEZENDOL 50MG CAPSULE is not recommended for use in patients with impaired heart function. It should be used with caution in patients with high blood pressure or heart disease. Consult your doctor before taking ZENDOL 50MG CAPSULE. OTHERSZENDOL 50MG CAPSULE is not recommended for use if you: ever had blood clots (thrombosis) have porphyria (a rare inherited illness which affects your metabolism) have a type of cancer which is influenced by hormones have unusual vaginal bleeding which is unchecked by a doctor Before taking ZENDOL 50MG CAPSULE, inform your doctor if you: have an illness which could be worsened by fluid retention have diabetes (high blood sugar levels) have epilepsy (fits) have polycythaemia (an illness in which the blood gets thicker) get migraines have cancer or possible breast cancer are about to have any procedure Use in paediatrics: Safety and effectiveness of ZENDOL 50MG CAPSULE in children has not been established. Use in geriatrics: Safety and effectiveness of ZENDOL 50MG CAPSULE in elderly patients (aged above 65 years) has not been established.
Drug Interactions
SA. Drug-Drug interactions: Before taking ZENDOL 50MG CAPSULE, inform your doctor if you are taking any of the following medicines: steroids (used in oral contraception and hormone replacement therapy) Ex. testosterone, estrogen, progesterone medicines used to lower blood cholesterol levels (Ex. simvastatin, atorvastatin) medicines used to manage fits (Ex. phenytoin, carbamazepine) medicines used to thin the blood (Ex. warfarin, clopidogrel) anaesthetics (used to manage pain during procedures) Ex. midazolam, propofol medicines used to stop the rejection of organs after a transplant (Ex. ciclosporin and tacrolimus) alpha calcidol (used for vitamin D deficiency and illness where there is lack of calcium in the blood) medicines used to lower blood sugar levels (Ex. metformin, glyburide) medicines used to manage high blood pressure (Ex. atenolol, diltiazem) medicines used to manage migraine (Ex. sumatriptan, rizatriptan) Overdosage: If you or anyone else accidentally take too much of ZENDOL 50MG CAPSULE, consult your doctor immediately or visit the nearby hospital. SYNOPSIS Drug : Danazol Pharmacological Category : Androgens Therapeutic Indication : Hormonal issues Dosage Forms : Tablet, Capsule MORE INFORMATION Keep ZENDOL 50MG CAPSULE out of reach of children Store at room temperature
Article Information
Written By
DETAILS Written By Dr. R. Dinesh John Rajkumar
Medical Content Writer
Reviewed By
Dr. Sankara Babu Gorle
Medical Expert
Last Updated
28 Nov 2022