Velpaclear 400/100mg Tablet 28'S
Key Information
Generic Name
Generic Name Sofosbuvir 400 mg+Velpatasvir 100 mg
Manufacturer
Abbott India Ltd
Variant
28 Tablet(s) in a Bottle
Country of Origin
India
Detailed Information
Introduction
VELPACLEAR 400/100MG TABLET is a combination of Sofosbuvir and Velpatasvir which belongs to the group of medicines called Antiviral agents. It is used to manage chronic (long-term) Hepatitis C infection. Hepatitis C infection is a viral infection caused due to hepatitis C virus. It predominantly affects the liver and ca
Uses
severe liver damage. It spreads mostly through contact with blood from an infected person (such as through sharing needles). VELPACLEAR 400/100MG TABLET is suitable for use both in adults and in children (aged 3 years or above). Before taking VELPACLEAR 400/100MG TABLET inform your doctor if you have diabetes, kidney problems or any other liver problems apart from hepatitis C infection (such as liver transplant or hepatitis B infection). Do not take VELPACLEAR 400/100MG TABLET without consulting your doctor if you are pregnant or breastfeeding. During management with VELPACLEAR 400/100MG TABLET, your doctor will regularly monitor your blood sugar levels and blood count to access improvement in your health condition and to avoid the risk of unwanted
How It Works
VELPACLEAR 400/100MG TABLET is an antiviral agent. It acts by blocking the actions of certain viral enzymes (HIV-reverse transcriptase) that is required for the viral cell to grow and multiply. As a result, it controls the multiplication of harmful viral cells within the body which reduces the severity of the infection.
Directions for Use
Take VELPACLEAR 400/100MG TABLET as directed by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. VELPACLEAR 400/100MG TABLET can be taken with or without meals. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and severity of the infection. Do not stop taking VELPACLEAR 400/100MG TABLET without consulting your doctor as it may reduce its effectiveness.
Side Effects
taking VELPACLEAR 400/100MG TABLET are headache, tiredness and skin rashes. Consult your doctor if they trouble you. USES OF VELPACLEAR 400/100MG TABLET Manage chronic Hepatitis C infection HOW VELPACLEAR 400/100MG TABLET WORKSVELPACLEAR 400/100MG TABLET is an antiviral agent. It acts by blocking the actions of certain viral enzymes (HIV-reverse transcriptase) that is required for the viral cell to grow and multiply. As a result, it controls the multiplication of harmful viral cells within the body which reduces the severity of the infection. DIRECTIONS FOR USETake VELPACLEAR 400/100MG TABLET as directed by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. VELPACLEAR 400/100MG TABLET can be taken with or without meals. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and severity of the infection. Do not stop taking VELPACLEAR 400/100MG TABLET without consulting your doctor as it may reduce its effectiveness. SIDE EFFECTS OF VELPACLEAR 400/100MG TABLETCOMMON headache tiredness skin rash RAREStop taking VELPACLEAR 400/100MG TABLET and contact your doctor immediately if you experience any of the following side effects: signs of allergic reactions (such as skin rash, itching, swelling of the face, lips, nose, throat which causes difficulty in breathing or swallowing) severe skin reactions causing widespread skin rashes with severe itching, blistering and peeling of skin, accompanied with fever, flu-like symptoms and ulcers in the mouth, eyes and/or genitals)
Warnings & Precautions
& PRECAUTIONSPREGNANCYThere is no proper information regrading the use of VELPACLEAR 400/100MG TABLET during pregnancy. Therefore, if you are pregnant or think you may be pregnant, consult your doctor before taking this medicine. Pregnancy should be avoided if this medicine is combined with another antiviral agent known as ribavirin. BREASTFEEDINGVELPACLEAR 400/100MG TABLET may pass through the breast milk. Therefore, it is not recommended for use in breastfeeding women. Consult your doctor for advice before taking it. DRIVING AND USING MACHINESDo not drive or handle any machines if your ability is affected by VELPACLEAR 400/100MG TABLET. KIDNEYVELPACLEAR 400/100MG TABLET should be used with caution in patients with kidney problems (such as dialysis). Therefore, consult your doctor before taking it. LIVERVELPACLEAR 400/100MG TABLET should be used with caution in patients with other liver problems apart from hepatitis C infection such as awaiting a liver transplant or hepatitis B infection. Therefore, consult your doctor before taking it. ALLERGYDo not take VELPACLEAR 400/100MG TABLET if you are allergic to Velpatasvir or Sofosbuvir. HEART DISEASEVELPACLEAR 400/100MG TABLET should be used with caution if you have heart problems. Consult your doctor for advice. OTHERSBefore taking VELPACLEAR 400/100MG TABLET, inform your doctor if you: are taking medicines for any on-going viral infections have diabetes Use in Paediatrics: VELPACLEAR 400/100MG TABLET is not recommended for use in children aged below 3 years. Therefore, consult your doctor before taking it. Use in Geriatrics: VELPACLEAR 400/100MG TABLET should be used with caution in elderly people. Therefore, consult your doctor before taking it.
Drug Interactions
SA. Drug - Drug interactions: Before taking VELPACLEAR 400/100MG TABLET inform your doctor if you are taking any of the following medicines such as: rifampicin, rifabutin, rifapentine (used to manage tuberculosis) St. John’s wort (a medicine used to manage depression) medicines used to manage epilepsy (such as carbamazepine, phenobarbital, phenytoin, oxcarbazepine) rosuvastatin (a medicine used to manage high blood cholesterol levels) amiodarone, digoxin (used to manage irregular heart rate) warfarin, dabigatran, vitamin k antagonists (used for blood thinning) medicines used to suppress your immune system (such as tacrolimus, cyclosporine) tenofovir disoproxil fumarate, tipranavir (used to manage HIV infection) medicines used to manage stomach ulcers or heartburn (such as aluminium hydroxide, omeprazole, lansoprazole, rabeprazole, pantoprazole, esomeprazole, famotidine, cimetidine, nizatidine or ranitidine) Overdosage: If you or anyone else accidentally took more VELPACLEAR 400/100MG TABLET, consult your doctor immediately. SYNOPSIS Drug : Velpatasvir, Sofosbuvir Pharmacological Category : HCV NS5A inhibitors, nucleotide polymerase inhibitors Therapeutic Indication : Hepatitis C infection Dosage Forms : Tablet MORE INFORMATION Keep VELPACLEAR 400/100MG TABLET out of reach of children Store VELPACLEAR 400/100MG TABLET at room temperature
Article Information
Written By
DETAILS Written By Srilekha. R
Medical Content Writer
Reviewed By
Dr. Sankara Babu Gorle
Medical Expert
Last Updated
05 Jan 2023