Valgress CR 300mg Tablet 10'S
Key Information
Generic Name
Generic Name Sodium Valproate 200 mg+Sodium Valproate 87 mg
Manufacturer
La Renon Healthcare Pvt Ltd
Variant
10 Tablet(s) in a Strip
Country of Origin
India
Detailed Information
Introduction
VALGRESS CR 300MG TABLET is a combination of Sodium valproate and Valproic acid, which belong to the group of medicines called Anticonvulsant/Antiepileptic drugs. It is used to manage epilepsy in adults and children. It is also used to manage bipolar disorders. Epilepsy is an abnormal electrical activity in the brain and nervous system. The symptoms may include temporary confusion, muscle stiffness, jerky movements in legs or arms, loss of consciousness, psychological symptoms (such as anxiety or fear), etc. VALGRESS CR 300MG TABLET is not recommended for use in patients with liver problems or with a family history of liver problems, porphyria (a hereditary disease that affects the skin or nervous system), blood coagulation or clotting disorders, pancreatic diseases (inflammation of the pancreas), urea cycle disorder (a genetic disorder) or Alpers-Huttenlocher syndrome (a rare disorder that affects brain, liver & muscles), etc. VALGRESS CR 300MG TABLET should be used with caution in patients with kidney problems or lung diseases (such as chronic obstructive pulmonary disease) and diabetes. VALGRESS CR 300MG TABLET is also not recommended for use in pregnant and breastfeeding women. It should be used with caution in children (below 2 years of age). Consult your doctor before taking the medicine. The common
Uses
OF VALGRESS CR 300MG TABLET Manage epilepsy Manage bipolar disorders
How It Works
VALGRESS CR 300MG TABLET helps in managing epilepsy, where sodium valproate and valproic acid effectively increases the GABA (a neurotransmitter/chemical messenger) concentration in the central nervous system by reducing its degradation. It also blocks certain ion channels which reduce high-frequency neuronal activity in the brain, thereby reliving seizure activity.
Directions for Use
Take VALGRESS CR 300MG TABLET as advised by your physician. Swallow the medicine with a glass of water with or after food. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending on your age, body weight and disease condition.
Side Effects
taking VALGRESS CR 300MG TABLET may include dizziness, headache, sleep disorders, clumsiness/unsteadiness, trembling of hands and arms and nervousness. Consult your doctor if any of the symptoms worsen or persist. USES OF VALGRESS CR 300MG TABLET Manage epilepsy Manage bipolar disorders HOW VALGRESS CR 300MG TABLET WORKSVALGRESS CR 300MG TABLET helps in managing epilepsy, where sodium valproate and valproic acid effectively increases the GABA (a neurotransmitter/chemical messenger) concentration in the central nervous system by reducing its degradation. It also blocks certain ion channels which reduce high-frequency neuronal activity in the brain, thereby reliving seizure activity. DIRECTIONS FOR USETake VALGRESS CR 300MG TABLET as advised by your physician. Swallow the medicine with a glass of water with or after food. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending on your age, body weight and disease condition. SIDE EFFECTS OF VALGRESS CR 300MG TABLETCOMMON headache sleep disorders clumsiness or unsteadiness trembling of hands and arms nervousness changing moods blurred vision ringing in ears deafness dizziness flu abdominal or stomach pain heartburn nausea and vomiting diarrhoea skin rash hair loss or thinning of hair back pain change in menstrual periods lack or loss of strength mental confusion aggression convulsion memory problems becoming unreactive bedwetting signs of liver damage such as skin and eyes that appear yellowish (jaundice), abdominal pain and swelling. signs of inflammation of the pancreas (pancreatitis) such as upper abdominal pain, abdomen tenderness, fever and rapid pulse signs of Fanconi syndrome (a disorder of kidney tubes) such as excessive thirst, urination, vomiting overgrown gum tissue agitation disturbance in attention abnormal behaviour hyperactivity learning disorder UNCOMMON unusual bleeding or bruising abnormal dreams anxiety feeling sad irritability pain in joints cough constipation dry eyes spots before the eyes ear infection ear pain runny nose dental pain bloating muscle pains or stiffness tiredness weight gain or loss learning disorder coma loss of muscle control brittle bones and fractures shortness of breath chest pain blood clotting problems RAREStop taking VALGRESS CR 300MG TABLET and contact your doctor if you experience any of the following side effects: signs of allergic reactions such as swelling of the face, lips, eyelids, throat and tongue, which may cause difficulty in breathing and swallowing signs of altered levels of ammonia in the blood characterized by vomiting, balance issues and lack of alertness signs of liver problems characterized by nausea, vomiting, tiredness, sleepiness, weakness, stomach pain, yellowing of the skin or whites of the eye signs of inflammation of the pancreas characterized by acute abdominal pain chest pain shortness of breath hallucinations suicidal thoughts psychosis (mental disorder causing disconnection from reality) toxic epidermal necrolysis (life-threatening skin disorder causing widespread skin pain, rashes, blisters, sores and crusting) Steven-Johnson syndrome (a skin disorder characterized by painful rashes and blisters on the skin) anaphylaxis (severe allergic reaction characterized by shortness of breath, fainting or fastened heartbeat) erythema multiforme (a skin condition characterized by raised red rashes on the skin) polycystic ovarian syndrome (a disorder of ovaries characterized by irregular periods, hair growth on the skin, acne and weight gain) brain diseases such as cerebral pseudo atrophy (loss of brain cells), encephalopathy (disease altering brain structure and functions) and coma (loss of consciousness) signs of thrombocytopenia (a condition marked by decreased platelet count) such as spontaneous bruising or bleeding signs of agranulocytosis (severe decrease of white blood cells or bone marrow failure) such as fever and breathing difficulty signs of anaemia (decreased red blood cell count) as weakness, dizziness, pale skin and shortness of breath signs of macrocytosis (abnormally increased red blood cell size) such as brittle nails, loss of weight or diarrhoea signs of pancytopenia (decreased blood cells and platelets) such as weakness, dizziness, pale skin and shortness of breath drowsiness change in consciousness level (including coma) confusion memory loss abnormal behaviour such as changes in attention, concentration, mood, hallucinations or fits of more frequency and severity signs of hypothyroidism (underactive thyroid gland) such as tiredness or weight gain signs of pleural effusion (build-up of fluid between the tissues that line the lungs and the chest) such as breathing difficulty and pain increase in the number and severity of convulsions signs of rhabdomyolysis (a disorder caused by the breakdown of muscle tissue) such as muscle pain and weakness signs of systemic lupus erythematosus (autoimmune disorder) such as joint pain, fever, fatigue or rash signs of increased ammonia in the blood, such as problems in balancing and co-ordination, feeling lethargic or less alert associated with vomiting shakiness (tremor) jerky muscle movements unsteadiness when walking due to parkinsonism (brain disorder), extrapyramidal disorder or ataxia (a disorder marked by impaired coordination) uncontrollable and rapid movement of the eyes signs of kidney disease such as renal failure, tubulointerstitial nephritis such as blood in the urine, fever, increased or decreased urine output, weakness, confusion signs of Fanconi syndrome (a disorder of kidney tubes) such as excessive thirst, urination and vomiting manifest as reduced urinary output or blood in the urine signs of decreased blood sodium levels such as confusion confusion that occurs due to decreased sodium levels in blood and syndrome of Inappropriate Antidiuretic Hormone (SIADH) secretion (a condition marked by high levels of the antidiuretic hormone that causes retention of water in the body)
Warnings & Precautions
& PRECAUTIONSPREGNANCYVALGRESS CR 300MG TABLET is not recommended for use by pregnant women. Women with childbearing potential should use effective contraception methods while taking VALGRESS CR 300MG TABLET. Consult your doctor before taking the medicine. BREASTFEEDINGVALGRESS CR 300MG TABLET is not recommended for use by breastfeeding mothers, as it may pass through breastfed milk. Consult your doctor before taking VALGRESS CR 300MG TABLET. DRIVING AND USING MACHINESAvoid driving or operating machines, if you feel drowsy or sleepy after taking VALGRESS CR 300MG TABLET. ALCOHOLAvoid consuming alcohol while taking VALGRESS CR 300MG TABLET. KIDNEYVALGRESS CR 300MG TABLET should be used with caution in patients with kidney diseases. Consult your doctor for advice before taking VALGRESS CR 300MG TABLET. LIVERVALGRESS CR 300MG TABLET is not recommended for use in patients with liver problems or any family history of liver problems such as severe hepatic dysfunction, particularly due to some medicine. Consult your doctor for advice before taking VALGRESS CR 300MG TABLET. ALLERGYVALGRESS CR 300MG TABLET is not recommended for use if you are allergic to Valproic acid, Sodium valproate or any other ingredients in this medicine. LUNGSVALGRESS CR 300MG TABLET should be used with caution in patients with lung diseases such as chronic obstructive pulmonary disease. Consult your doctor for advice before taking VALGRESS CR 300MG TABLET. OTHERSVALGRESS CR 300MG TABLET is not recommended for use if you: have porphyria (a hereditary disease that affects the skin or nervous system) have blood coagulation or clotting disorders such as deep vein thrombosis, pulmonary embolism have pancreatic diseases have signs of urea cycle disorder (excessive ammonia build-up in the body) such as loss of appetite, vomiting and lethargy that causes excessive ammonia builds up in the body have a genetic disorder called Alpers-Huttenlocher syndrome (a progressive, neurodevelopmental syndrome characterized by three co-occurring clinical symptoms which are psychomotor regression (dementia); seizures; and liver disease) Before taking VALGRESS CR 300MG TABLET, inform your doctor if you: have diabetes are scheduled for surgery such as dental surgery have systemic lupus erythematosus (a disease of the immune system that affects bones, joints and body organs) have a certain brain disease or any metabolic condition affecting your brain such as hypoglycaemic encephalopathy have a deficiency condition such as carnitine palmitoyl transferase type II deficiency (a condition that manages the body from using certain fats for energy, particularly during periods without food) Use in Paediatrics: VALGRESS CR 300MG TABLET should be used with caution in children (below 2 years of age). Consult your doctor before taking VALGRESS CR 300MG TABLET. Use in Geriatrics: VALGRESS CR 300MG TABLET should be used with caution in elderly patients (aged above 68 years). Consult your doctor before taking VALGRESS CR 300MG TABLET.
Drug Interactions
SA. Drug-Drug Interactions: Before taking VALGRESS CR 300MG TABLET, inform your doctor, if you are taking any of the following medicine: medicines used to manage depression or Parkinson’s disease, such as monoamine oxidase inhibitors (MAOI) Ex. selegiline, phenelzin medicines used to manage emotional and mental conditions Ex. diazepam, olanzapine medicine used to manage HIV infection Ex. zidovudine medicines used for thinning the blood Ex. warfarin other medicines used to manage epilepsy Ex. phenytoin, phenobarbital, carbamazepine, primidone, rufinamide, topiramate, acetazolamide, lamotrigine and felbamate medicines used to manage pain and inflammation such as salicylates Ex. aspirin medicines used to manage malaria Ex. mefloquine, chloroquine medicines used to manage stomach ulcers Ex. cimetidine antibiotics or medicines used to manage bacterial infections such as carbapenem agents Ex. imipenem, meropenem, ertapenem, erythromycin medicines used to lower blood cholesterol Ex. cholestyramine medicines used to manage tuberculosis Ex. rifampicin medicines used to manage cancer Ex. temozolomide medicines used to manage bleeding in the brain Ex. nimodipine medicines used to anaesthetise Ex. Propofol medicines used for birth control Ex. oestrogen-containing products medicines used to manage pain and fever Ex. metamizole Overdosage If you or anyone else accidentally takes too much of VALGRESS CR 300MG TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose may include nausea, vomiting, headache, blurred vision, dizziness, poor reflexes, confusion, memory loss, tiredness, muscle weakness, fits, loss of consciousness, behavioural changes and breathing difficulties such as fast breathing or shortness of breath or chest pain. SYNOPSIS Drug : Sodium valproate, Valproic acid Pharmacological Category : Anticonvulsants/Antiepileptics Therapeutic Indication : Epilepsy, Bipolar disorder Dosage Forms : Tablet MORE INFORMATION Keep VALGRESS CR 300MG TABLET out of reach from children Store VALGRESS CR 300MG TABLET at room temperature
Article Information
Written By
DETAILS Written By Dr. Dhivakaran R
Medical Content Writer
Reviewed By
Dr. Sankara Babu Gorle
Medical Expert
Last Updated
12 Dec 2022