UNOPAN D Tablet 10's
Key Information
Generic Name
Generic Name Domperidone 10 mg+Pantoprazole 40 mg
Manufacturer
SHANKUS ACME PHARMA PVT LTD
Variant
10 Tablet(s) in a Strip
Country of Origin
India
Detailed Information
Introduction
UNOPAN D TABLET is used to manage peptic ulcers, gastroesophageal reflux disease (GERD) and reflux esophagitis. It is a combination of Domperidone and Pantoprazole which belongs to the group of medicines called Prokinetic Drugs and Proton pump inhibitors respectively. UNOPAN D TABLET acts by reducing the production of gastric acid. It also speeds up the movement of food from the stomach to the intestines, thereby reducing the signs of nausea, vomiting and acid reflux. Due to these actions, it can also reduce the unpleasant signs of GI tract such as nausea, vomiting, indigestion, burping, bloating, acidity or heartburn. It should be taken at least 15-30 minutes before meals. During management with UNOPAN D TABLET your doctor will closely monitor your kidney functions, liver functions and blood magnesium levels to avoid the risk of unwanted
Uses
OF UNOPAN D TABLETIt is used to manage: Peptic ulcer Gastrointestinal Reflux disease (GERD) Reflux esophagitis (inflammation of the esophagus) Nausea and Vomiting Acidity, Heartburn Signs of indigestion (such as burping, bloating)
How It Works
UNOPAN D TABLET contains Domperidone and Pantoprazole. Domperidone is a prokinetic medicine with anti-emetic properties which works by blocking the actions of a chemical messenger called dopamine in the gut and across the brain and spinal cord. This action stimulates the gut, reduces acid reflux and speeds up the movements of food from the stomach into the intestines. It also blocks the transmission of nerve signals between the vomiting centers and brain which reduces the onset of nausea and vomiting. Pantoprazole reduces gastric acid secretion by the blocking the actions of a protein membrane called H+K+Atpase (proton pump) present in the lining of the stomach. By reducing stomach acid production, UNOPAN D TABLET it manages the worsening of ulcers, heals the existing ulcers and esophageal lesions and provides relief from the unpleasant symptoms of GI tract (such as acidity, bloating, burping and indigestion).
Directions for Use
Take UNOPAN D TABLET 15-30 minutes before meals or as advised by your physician Swallow the medicine with a glass of water. Do not crush or chew the medicine Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition Do not stop taking UNOPAN D TABLET unless your doctor advice you to stop
Side Effects
mouth, constipation and flatulence. Consult your doctor if any of these side effect bothers you. You must also inform your doctor immediately if you experience any signs of low magnesium levels in blood (such as tiredness, abnormal muscle movements, dizziness, confusion, disorientation, irregular heartbeat). USES OF UNOPAN D TABLETIt is used to manage: Peptic ulcer Gastrointestinal Reflux disease (GERD) Reflux esophagitis (inflammation of the esophagus) Nausea and Vomiting Acidity, Heartburn Signs of indigestion (such as burping, bloating) HOW UNOPAN D TABLET WORKSUNOPAN D TABLET contains Domperidone and Pantoprazole. Domperidone is a prokinetic medicine with anti-emetic properties which works by blocking the actions of a chemical messenger called dopamine in the gut and across the brain and spinal cord. This action stimulates the gut, reduces acid reflux and speeds up the movements of food from the stomach into the intestines. It also blocks the transmission of nerve signals between the vomiting centers and brain which reduces the onset of nausea and vomiting. Pantoprazole reduces gastric acid secretion by the blocking the actions of a protein membrane called H+K+Atpase (proton pump) present in the lining of the stomach. By reducing stomach acid production, UNOPAN D TABLET it manages the worsening of ulcers, heals the existing ulcers and esophageal lesions and provides relief from the unpleasant symptoms of GI tract (such as acidity, bloating, burping and indigestion). DIRECTIONS FOR USE Take UNOPAN D TABLET 15-30 minutes before meals or as advised by your physician Swallow the medicine with a glass of water. Do not crush or chew the medicine Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition Do not stop taking UNOPAN D TABLET unless your doctor advice you to stop SIDE EFFECTS OF UNOPAN D TABLETCommon side effects of UNOPAN D TABLET: benign polyps in the stomach dry mouth headache, dizziness, drowsiness diarrhea, constipation, stomach pain, flatulence Stop taking UNOPAN D TABLET and inform your doctor immediately if you experience any of the following side effects such as: severe allergic reactions (such as skin rash, itching, swelling of the lips, face or body and difficulty in breathing or swallowing) signs of liver problems (yellowing of the skin and eyes, dark urine and tiredness) severe skin reactions (such as redness, blistering, peeling of skin and bleeding in the lips, eyes, mouth, nose and genitals with fever) signs of kidney problem (such as lower back pain, painful urination) signs of low magnesium levels in blood (such as tiredness, abnormal muscle movements, dizziness, confusion, disorientation, irregular heartbeat) severe, persistent diarrhea fast or irregular heartbeat, difficulty in breathing, feeling faint fits uncontrollable body movements (including eye and tongue), twisted neck and abnormal body posture
Warnings & Precautions
& PRECAUTIONSPREGNANCYMonitoring requiredUNOPAN D TABLET should be used in pregnant women only if it is considered necessary by the physician. BREASTFEEDINGMonitoring requiredUNOPAN D TABLET may pass through breast milk. Therefore, it should be used in breastfeeding women only if it is considered necessary by the physician. DRIVING AND USING MACHINESUse with CautionUNOPAN D TABLET does not affect your ability in driving or handling heavy tools or machines. However, do not drive or handle heavy tools or machines if your ability is affected by the medicine. ALCOHOLConsult your doctorAvoid consumption of alcohol while taking UNOPAN D TABLET, as it could aggravate your existing condition. KIDNEYUse with CautionUNOPAN D TABLET should be used with caution in patients with kidney problems. LIVERConsult your doctorUNOPAN D TABLET is not recommended for use in patients with moderate or severe liver impairment. It should be used with caution in patients with other mild liver problems. ALLERGYContraindicatedDo not take UNOPAN D TABLET if you are allergic to Domperidone, Pantoprazole or to any other ingredients of this medicine. HEART DISEASEContraindicatedUNOPAN D TABLET is not recommended for use in patients with heart problems such as prolongation of QT interval or congestive heart failure. USE IN PEDIATRICSContraindicatedUNOPAN D TABLET is not recommended for use in children and adolescents (aged below 18 years). USE IN GERIATRICSUse with CautionUNOPAN D TABLET should be used with caution in elderly patients (aged 65 years and above). OTHERSUNOPAN D TABLET is not recommended for use if you: have bloody stools or bleeding in the gut have blockage or tear in the intestines have severe fluid or electrolyte disturbances have prolactinoma (a non-cancerous tumor of pituitary gland) have low blood potassium or magnesium levels Before taking UNOPAN D TABLET inform your doctor if you: have osteoporosis have vitamin B12 deficiency (sore tongue, mouth ulcers, pale skin, depression) are going to test Chromogranin A level
Drug Interactions
SA. Drug-Drug interactions: Before taking UNOPAN D TABLET inform your doctor if you are taking any of the following medicines such as: Aminobenzamides (Ex. cisapride, dolasetron, prucalopride, diphemanil) Cardiac glycosides (Ex. digoxin, apomorphine, disopyramide, hydroquinidine, quinidine, amiodarone, dofetilide, dronedarone, ibutilide, sotalol, diltiazem or verapamil) Anti-viral agents (Ex. atazanavir, nelfinavir, saquinavir, telaprevir) Antifungal (Ex. ketoconazole, itraconazole, posaconazole) Anti-coagulants (Ex. warfarin, phenprocoumon) Antipsychotics (Ex. haloperidol, pimozide, sertindole) Antidepressants (Ex. escitalopram or citalopram, fluvoxamine, St John’s wort) Antibiotics (Ex. moxifloxacin, erythromycin, levofloxacin, clarithromycin, telithromycin or amoxicillin) Phenanthrene class (Ex. halofantrine, lumefantrine) Antihistamines (Ex. mizolastine, mequitazine) Anti-cancer agents (Ex. toremifene, vandetanib, vincamine, erlotinib, dasatinib, nilotinib) Antimetabolites (Ex. methotrexate) Anti-arrhythmic (Ex. bepridil) Opiate (narcotic) analgesics (Ex. methadone) Iron salts Immunosupressants (Ex. tacrolimus or mycophenolate mofetil) Anti-infective (Ex. pentamidine) Anti-TB agents (Ex. rifampicin) Overdosage: If you or anyone else accidentally took more UNOPAN D TABLET, contact your doctor immediately or go to a hospital straight away. Symptoms of overdosage might include sleepiness, confusion, uncontrollable body movements (including eye and tongue), twisted neck and abnormal body posture. SYNOPSIS Drug : Domperidone, Pantoprazole Pharmacological Category : Dopamine D2 antagonists, Proton-pump inhibitors Therapeutic Indication : Peptic ulcer, GERD, Reflux esophagitis Dosage Forms : Tablet, Capsule MORE INFORMATION
Frequently Asked Questions
Common questions and answers about UNOPAN D Tablet 10's.
What is UNOPAN D TABLET used for?
UNOPAN D TABLET is used to manage peptic ulcers, GERD and reflux esophagitis. It can also be used to manage nausea, vomiting, bloating, burping, acidity and heartburn.
How and when to take UNOPAN D TABLET?
Take UNOPAN D TABLET at least 15-30 minutes before meals. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition.
How long should I take UNOPAN D TABLET?
You need to take UNOPAN D TABLET for the stipulated duration prescribed by your doctor. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition.
What is the best time to take UNOPAN D TABLET?
UNOPAN D TABLET must be taken before meals to avoid gastrointestinal side effects.
What to do if I forgot to take a dose of UNOPAN D TABLET?
If you forgot to take a dose of UNOPAN D TABLET, take it as soon as you remember. However, if it is time for the next dose of UNOPAN D TABLET, skip the missed dose and take the next one regularly.
What are the most common side effects of taking UNOPAN D TABLET?
The most common side effects are dryness of mouth, constipation and flatulence. Consult your doctor if any of these side effect bothers you.
Will taking a higher dose of UNOPAN D TABLET be more effective?
No, taking a higher dose of UNOPAN D TABLET will not be effective rather it can lead to toxicity. Always take the dose prescribed by your doctor. If the prescribed dose is not effective for you, consult your doctor for advice. Your doctor might increase the dose or suggest an alternative therapy.
What precautions do I need to follow while taking UNOPAN D TABLET?
Make sure to take UNOPAN D TABLET 30 minutes before meals. Before taking UNOPAN D TABLET inform your doctor if you have any liver, kidney or heart problems. You must also inform your doctor if you have any blockage or tears in the gut or have weak bones.
Can I take medication for high blood pressure along with UNOPAN D TABLET?
It is not advisable to take medicines to control blood pressure while taking UNOPAN D TABLET without consulting your doctor as they have known interactions with the medicine.
Can UNOPAN D TABLET be used in pregnant women?
UNOPAN D TABLET should be used in pregnant women only if it is considered necessary by the physician.
Can UNOPAN D TABLET cause constipation?
Yes. Constipation is a common side effect of using UNOPAN D TABLET. Eat plenty of fiber rich foods such as fresh fruits, vegetables, cereals as well as drink plenty of water and exercise more regularly when taking this medicine. Contact your doctor if this side effect bothers you.
Can UNOPAN D TABLET cause dry mouth?
Yes. Dry mouth is a common side effect of using UNOPAN D TABLET. Contact your doctor if this side effect bothers you.
Article Information
Written By
DETAILS Written By Srilekha. R
Medical Content Writer
Reviewed By
Dr. Sankara Babu Gorle
Medical Expert
Last Updated
20 Nov 2024