Trenaxa Injection 5ml
Key Information
Generic Name
Generic Name Tranexamic Acid 500 mg
Manufacturer
Macleods Pharmaceuticals Pvt Ltd
Country of Origin
India
Detailed Information
Introduction
INTRODUCTION ABOUT TRENAXA INJECTIONTRENAXA INJECTION contains Tranexamic Acid which belongs to the group of medicines called Antifibrinolytics. It is used in the management of bleeding in conditions such as heavy menstrual bleeding in women, gastrointestinal bleeding (bleeding in digestive tract, anywhere from the throat to rectum), bleeding due to thrombolytic therapy (medicine that is used to breakdown blood clots) and after having surgeries (such as ear, nose, throat, prostate gland, urinary tract, gynecological, abdominal or heart surgery) in adults and children above one year of age. TRENAXA INJECTION is not recommended for use in patients with severe kidney impairment, blood clotting disorder or consumption coagulopathy (condition affecting the blood’s ability to clot and stop the bleeding) or history of seizures (fits). Your doctor may recommend you to take relevant tests to understand your existing condition. Before receiving TRENAXA INJECTION, inform your doctor if you had or have blood in the urine, are at risk of having a blood clot, excessive clotting or bleeding throughout the body (disseminated intravascular coagulation). TRENAXA INJECTION is not recommended for use in the first trimester of pregnancy and in breast-feeding women. It should be used with caution in pregnant women only if clearly advised by the doctor. TRENAXA INJECTION should be used with caution in elderly patients, especially in patients with the evidence of renal failure. The most common
Uses
OF TRENAXA INJECTIONPrevent and manages bleeding in children (aged above one) and adults in conditions such as: heavy menstrual bleeding in women gastrointestinal bleeding after having surgeries (such as ear, nose, throat, heart, abdominal, gynaecological and prostrate or urinary tract surgery) bleeding due to medicine that is used to breakdown blood clots (thrombolytic therapy)
How It Works
TRENAXA INJECTION manages bleeding by blocking the plasminogen from binding with fibrin which results in bleeding. As a result, it manages and controls bleeding associated with various factors.
Directions for Use
TRENAXA INJECTION will be given to you only by a doctor or a nurse into a vein as an intravenous injection. Your doctor will decide the correct dose, frequency and duration for you depending upon your age, body weight and disease condition.
Side Effects
receiving TRENAXA INJECTION are nausea or vomiting and diarrhea. Inform your doctor immediately if any of the side effect worsens. USES OF TRENAXA INJECTIONPrevent and manages bleeding in children (aged above one) and adults in conditions such as: heavy menstrual bleeding in women gastrointestinal bleeding after having surgeries (such as ear, nose, throat, heart, abdominal, gynaecological and prostrate or urinary tract surgery) bleeding due to medicine that is used to breakdown blood clots (thrombolytic therapy) HOW TRENAXA INJECTION WORKSTRENAXA INJECTION manages bleeding by blocking the plasminogen from binding with fibrin which results in bleeding. As a result, it manages and controls bleeding associated with various factors. DIRECTIONS FOR USETRENAXA INJECTION will be given to you only by a doctor or a nurse into a vein as an intravenous injection. Your doctor will decide the correct dose, frequency and duration for you depending upon your age, body weight and disease condition. SIDE EFFECTS OF TRENAXA INJECTIONCOMMON diarrhea nausea, vomiting UNCOMMON skin rashes RAREInform your doctor immediately if you experience any of the following side effects while receiving TRENAXA INJECTION: severe allergic reaction (signs include redness of the skin and lumpy skin rashes, difficulty in breathing, swelling of face, mouth, lips or eyelids, unexplained high temperature (fever) and fainting) swelling of the throat that causes breathing and swallowing difficulty symptoms of a blood clot (such as swelling or pain in the legs or chest, headache, weakness of the face and limbs on one side of the body)
Warnings & Precautions
& PRECAUTIONSPREGNANCYContraindicatedTRENAXA INJECTION is not recommended for use in the first trimester of pregnancy. It should be used with caution in pregnant women only if considered clearly necessary. Women of childbearing potential should use effective contraception during management with this medicine. Consult your doctor before receiving TRENAXA INJECTION. BREASTFEEDINGContraindicatedTRENAXA INJECTION is not recommended for use in breastfeeding women as it passes through breast milk. Consult your doctor for advice. KIDNEYConsult your doctorTRENAXA INJECTION is not recommended for use in patients with severe kidney impairment. It should be used with caution in patients with mild to moderate kidney impairment. Your doctor may adjust the dose depending upon the kidney function. Consult your doctor before receiving TRENAXA INJECTION. LIVERUse with CautionTRENAXA INJECTION can be used with caution in patients with liver impairment. Consult your doctor before receiving TRENAXA INJECTION. ALLERGYContraindicatedDo not receive TRENAXA INJECTION if you are allergic to Tranexamic acid or any other ingredients of this medicine. USE IN PEDIATRICSUse with CautionTRENAXA INJECTION should be used with caution in children above 1 year of age. Your child’s doctor will adjust the dose based on the bodyweight of the child. Consult child’s doctor for advice before administration of TRENAXA INJECTION. USE IN GERIATRICSUse with CautionTRENAXA INJECTION should be used with caution in elderly patients, especially in patients with the evidence of renal failure. Consult your doctor before receiving TRENAXA INJECTION. OTHERSTRENAXA INJECTION is not recommended for use if you: have blood clotting disorder or consumption coagulopathy (condition affecting the blood’s ability to clot and stop the bleeding) have history of seizures (fits) Before receiving TRENAXA INJECTION, inform your physician if you: have blood in the urine (which may lead to urinary tract obstruction) are at risk of having a blood clot have excessive clotting or bleeding throughout the body (disseminated intravascular coagulation)
Drug Interactions
SA. Drug-Drug interactions: Before receiving TRENAXA INJECTION, inform your doctor if you have received or taking any of the following medicines: ethinyl estradiol, levonorgestrel (oral contraceptives used to manage pregnancy) thrombolytic agents such as streptokinase, reteplase, tenecteplase (medicines that manage blood clot) antifibrinolytics such as aminocaproic acid, aprotinin (medicines that help the blood to clot) Overdosage: TRENAXA INJECTION will be given to you only by a doctor or nurse in a hospital, and so it is unlikely to receive an overdose. However, if you experience any unusual symptoms contact your doctor immediately. Symptoms include dizziness, headache, low blood pressure and convulsions (fits). SYNOPSIS Drug : Tranexamic Acid Pharmacological Category : Antifibrinolytics Therapeutic Indication : Prevent and manages bleeding in certain conditions Dosage Forms : Injection, Gel, Tablet MORE INFORMATION Store at room temperature
Frequently Asked Questions
Common questions and answers about Trenaxa Injection 5ml.
Can TRENAXA INJECTION be used in elderly patients?
TRENAXA INJECTION should be used with caution in elderly patients, especially in patients with the evidence of renal failure. Consult your doctor for advice before receiving TRENAXA INJECTION.
Is TRENAXA INJECTION safe to use during pregnancy?
TRENAXA INJECTION is not recommended for use in the first trimester of pregnancy. It should be used with caution in pregnant women only if clearly advised by the doctor. Women of childbearing potential should use effective contraception during management with this medicine. Consult your doctor before receiving TRENAXA INJECTION.
Can TRENAXA INJECTION be used in patients with impaired kidney function?
TRENAXA INJECTION is not recommended for use in patients with severe kidney impairment. It should be used with caution in patients with mild to moderate kidney impairment. Your doctor may adjust the dose depending upon the kidney function. Consult your doctor before receiving TRENAXA INJECTION.
Does TRENAXA INJECTION cause nausea?
Yes, TRENAXA INJECTION may cause nausea in some individuals. To manage this effect, stick to simple meals while receiving this medicine. Avoid eating oily rich, fried or spicy foods. Do not lie down or sleep immediately after eating. Inform your doctor if the symptom does not improve.
How TRENAXA INJECTION is administered?
TRENAXA INJECTION will be given to you only by a doctor or a nurse into a vein as an intravenous injection. It should not be injected into a muscle (intramuscularly). Your doctor will decide the correct dose, frequency and duration for you depending upon your age, body weight and disease condition.
Article Information
Written By
DETAILS Written By Dr. R. Dinesh John Rajkumar
Medical Content Writer
Reviewed By
Dr. Sankara Babu Gorle
Medical Expert
Last Updated
06 Mar 2023