Tolpa D Tablet 10'S
Key Information
Generic Name
Generic Name Diclofenac 50 mg+Serratiopeptidase 10 mg
Manufacturer
Micro Labs Ltd
Variant
10 Tablet(s) in a Strip
Country of Origin
India
Detailed Information
Introduction
TOLPA D TABLET is a combination of Diclofenac and Serratiopeptidase which belongs to a group of medicines called Nonsteroidal anti-inflammatory drugs and Proteolytic enzymes. TOLPA D TABLET is used in the management of pain and inflammatory conditions in adult patients. TOLPA D TABLET is not recommended for use in patients allergic to diclofenac, aspirin, ibuprofen, other NSAIDs, and/or serratiopeptidase. TOLPA D TABLET is also not recommended for use in patients with active gastric or intestinal ulcer/bleeding/perforation, active/previous history of recurrent peptic ulcer/hemorrhage, peripheral arterial disease (blood circulation disorder), severe liver/kidney impairment, and/or heart diseases (such as congestive heart failure, severe heart failure, ischemic heart disease). TOLPA D TABLET is also not indicated for use to manage pain in patients who had undergone coronary artery bypass graft (CABG) surgery. Before taking TOLPA D TABLET inform your doctor if you had previously suffered from gastrointestinal ulceration, and/or have ulcerative colitis (inflammation of colon), mixed connective tissue disorders (such as systemic lupus erythematosus), diabetes, high blood pressure, lung problems (such as bronchial asthma, chronic obstructive pulmonary diseases), kidney problems (such as mild to moderate renal impairment), and/or liver problems (such as mild to moderate liver impairment). TOLPA D TABLET is generally not recommended for use during third trimester of pregnancy which is also not recommended for use in women planning for pregnancy. TOLPA D TABLET should be used with caution during first and second trimester of pregnancy only if it is clearly necessary. TOLPA D TABLET is also not recommended for use in breastfeeding women since it may pass through breastmilk. Consult your doctor before taking the medicine. TOLPA D TABLET is not recommended for use in children and adolescents (aged below 18 years) at higher doses which should be used with caution in children and adolescents (aged above 14 years) at lower doses after consulting the doctor. TOLPA D TABLET should also be used with caution in elderly patients (aged above 65 years) after consulting the doctor. The most common
Uses
OF TOLPA D TABLET Used to manage pain and inflammatory conditions
How It Works
TOLPA D TABLET provides relief from pain and inflammation in affected individuals where diclofenac works by inhibiting the release of certain chemical messengers (responsible for pain and inflammation) in the brain and serratiopeptidase reduces inflammatory reaction by breaking down abnormal proteins at the site of inflammation thus providing relief from inflammation and pain in affected individuals.
Directions for Use
Take TOLPA D TABLET as advised by your physician. Your doctor will decide the correct dose, duration and frequency for you depending on your age, body weight and disease condition.
Side Effects
taking TOLPA D TABLET are headache, dizziness, abdominal pain, indigestion, nausea, vomiting, and/or diarrhea. Consult your doctor if any of these symptoms worsen. USES OF TOLPA D TABLET Used to manage pain and inflammatory conditions HOW TOLPA D TABLET WORKSTOLPA D TABLET provides relief from pain and inflammation in affected individuals where diclofenac works by inhibiting the release of certain chemical messengers (responsible for pain and inflammation) in the brain and serratiopeptidase reduces inflammatory reaction by breaking down abnormal proteins at the site of inflammation thus providing relief from inflammation and pain in affected individuals. DIRECTIONS FOR USETake TOLPA D TABLET as advised by your physician. Your doctor will decide the correct dose, duration and frequency for you depending on your age, body weight and disease condition. SIDE EFFECTS OF TOLPA D TABLETCOMMON Headache Dizziness Nausea Vomiting Diarrhea Indigestion abdominal pain flatulence anorexia (eating disorder) loss of appetite rash red itchy welts UNCOMMON racing heartbeat chest pain RARE Signs of hypersensitivity and anaphylactic reactions (life threatening allergic reactions) such as low blood pressure, red itchy welts, flushed/pale skin, shortness of breath, and/or wheezing Excess sleepiness, tiredness Asthma, difficulty in breathing Stomach inflammation, gastrointestinal bleeding, dark stools, bloody diarrhea, stomach ulcer with/without bleeding/perforation Inflammation of liver, jaundice, liver disorders Bullous eruptions, skin inflammation, skin redness, erythema multiforme (type of allergic skin reaction) Swelling in arms and legs Stop taking TOLPA D TABLET and contact your doctor immediately if you experience any of the following side effects: Skin rash, mucosal lesions, hypersensitivity reaction (associated with signs such as red itchy welts, skin rash, shortness of breath, wheezing, and/or fever) Stomach pain, indigestion, heartburn, wind, nausea, vomiting Signs of bleeding in the stomach/intestine such as abdominal cramps, black/tarry stool, bright red blood in vomit, and/or dizziness/faintness Signs of allergic reactions such as skin rash, itching, bruising, painful red areas, peeling/blistering Wheezing/shortness of breath Swollen face, lips, hands or fingers Signs of jaundice such as yellowing of your skin or the whites of your eyes Persistent sore throat/high temperature Change in quantity of urine and its appearance Mild cramping and tenderness of abdomen followed by rectal bleeding/bloody diarrhea usually within 24 hours of the onset of abdominal pain Signs of Stevens-Johnson syndrome (serious skin disorder) such as blistering of the skin, mouth, eyes and genitals Chest pain due to Kounis syndrome (serious allergic reaction)
Warnings & Precautions
& PRECAUTIONSPREGNANCYConsult your doctorTOLPA D TABLET is generally not recommended for use during third trimester of pregnancy. It is also not recommended for use in women planning for pregnancy. TOLPA D TABLET should be used with caution during first and second trimester of pregnancy only if it is clearly necessary. Consult your doctor before taking TOLPA D TABLET. BREASTFEEDINGContraindicatedTOLPA D TABLET is not recommended for use in breastfeeding women since it may pass through breastmilk. Consult your doctor before taking TOLPA D TABLET. DRIVING AND USING MACHINESUse with CautionDo not drive or operate any machines if you feel/experience visual disturbances, dizziness, spinning sensation, excess sleepiness, drowsiness, and/or tiredness after taking TOLPA D TABLET. ALCOHOLConsult your doctorAvoid consumption of alcohol while taking TOLPA D TABLET as it increases the risk of gastrointestinal bleeding. KIDNEYConsult your doctorTOLPA D TABLET is not recommended for use in patients with severe renal impairment. It should be used with caution in patients with mild to moderate renal impairment. Consult your doctor before taking TOLPA D TABLET. LIVERConsult your doctorTOLPA D TABLET is not recommended for use in patients with severe hepatic impairment and liver failure. It should be used with caution in patients with mild to moderate hepatic impairment and hepatic porphyria. Consult your doctor before taking TOLPA D TABLET. ALLERGYContraindicatedDo not take TOLPA D TABLET if you are allergic to diclofenac, aspirin, ibuprofen, other NSAIDs, serratiopeptidase, and/or any other ingredients of this medicine. LUNGSUse with CautionTOLPA D TABLET should be used with caution in patients with lung problems such as bronchial asthma, chronic obstructive pulmonary diseases, and/or chronic infections of the respiratory tract. Consult your doctor before taking TOLPA D TABLET. HEART DISEASEContraindicatedTOLPA D TABLET is not recommended for use in patients with established congestive heart failure, severe heart failure, and/or ischemic heart disease, It is also not recommended for use in patients who had undergone coronary artery bypass graft (CABG) surgery. Consult your doctor before taking TOLPA D TABLET. USE IN PEDIATRICSConsult your doctorTOLPA D TABLET is not recommended for use in children and adolescents (below 18 years) at higher doses. It should be used with caution in children and adolescents (aged above 14 years) at lower doses. Consult your doctor before taking the medicine who shall decide the correct dose, duration and frequency depending on the child’s age, body weight and disease condition. USE IN GERIATRICSUse with CautionTOLPA D TABLET should be used with caution in elderly patients (aged above 65 years). Consult your doctor before taking the medicine. OTHERSTOLPA D TABLET is not recommended for use if you: Have active gastric or intestinal ulcer/bleeding/perforation Previously suffered from gastrointestinal bleeding/perforation (due to NSADIS therapy) Have active/previous history of recurrent peptic ulcer/hemorrhage (with two or more bleeding episodes) Previously suffered from angio-oedema, red itchy welts, acute rhinitis gastrointestinal (due to NSAIDS therapy) Previously had stomach/bowel problems (after taking other NSAIDs) Have/had peripheral arterial disease (blood circulation disorder). Other cerebrovascular diseases (such as stroke, ministroke). Have rare hereditary problems of galactose intolerance, severe lactase deficiency/glucose-galactose malabsorption. Before taking TOLPA D TABLET, inform your doctor if you: Have previously suffered from gastrointestinal ulceration Have ulcerative colitis (inflammation of colon) or crohn’s disease (inflammatory bowel disease) Suffer from mixed connective tissue disorders such as systemic lupus erythematosus (type of autoimmune disease) Have diabetes, high blood pressure, hyperlipidemia (high cholesterol level in blood) Are a smoker Suffer from defective hemostasis (process to prevent/stop bleeding), bleeding diathesis/ hematological abnormalities (increased susceptibility to bleed)
Drug Interactions
SA. Drug-Drug interactions: Before taking TOLPA D TABLET, inform your doctor, if you are taking any of the following medicine: Lithium (used for depression) Digoxin, quinidine (medicines used to manage heart disease) Medicines used for hypertension such as diuretics (Ex. chlorothiazide, chlorthalidone), beta blockers (Ex. acebutolol, atenolol), angiotensin-converting enzyme inhibitors (Ex. benazepril, captopril) Potassium-sparing diuretic (used to manage hypertension, cirrhosis, congestive heart failure) Ex. amiloride, eplerenone Ciclosporin (used to manage transplant organ rejection) Tacrolimus (used to manage moderate to severe atopic dermatitis) Trimethoprim (used to manage urinary tract infections) Anticoagulants (medicines used to manage blood clot) Ex. aspirin, warfarin Other NSAIDS (medicines used to reduce pain and inflammation) such as cox 2 selective inhibitors (Ex. celecoxib, valdecoxib), corticosteroids (Ex. cortisone, hydrocortisone) Selective serotonin reuptake inhibitors (medicines used to manage depression) Ex. citalopram, dapoxetine Antidiabetics (medicines used to manage diabetes) Ex. metformin, glipizide, glyburide Methotrexate (used to manage inflammatory conditions) Quinolone (used to manage bacterial infections) Phenytoin (used to manage seizures) Colestipol, Cholestyramine (medicines used to lower high cholesterol in blood) Cardiac glycosides (medicines used to manage heart failure and certain irregular heartbeats) Ex. acetyldigitoxin, deslanoside Mifepristone (used to end early pregnancy) Overdosage: If you or anyone else accidentally take too much of TOLPA D TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose are headache, nausea, vomiting, epigastric pain, GI hemorrhage, diarrhea, dizziness, disorientation, excitation, coma, drowsiness, tinnitus, fainting, and/or convulsions. SYNOPSIS Drug : Diclofenac, Serratiopeptidase Pharmacological Category : Non-steroidal anti-inflammatory drug, Proteolytic Enzyme Therapeutic Indication : Pain and inflammatory conditions Dosage Forms : Capsule, Tablet, Orally Disintegrating Tablet MORE INFORMATIONSTORAGE Keep out of reach from children Store below 25°C
Frequently Asked Questions
Common questions and answers about Tolpa D Tablet 10'S.
What is TOLPA D TABLET and why it is used?
TOLPA D TABLET is a combination of Diclofenac and Serratiopeptidase which belongs to a group of medicines called Nonsteroidal anti-inflammatory drugs and Proteolytic enzymes, which is generally indicated in adult patients to manage pain and inflammatory conditions.
How TOLPA D TABLET works?
TOLPA D TABLET provides relief from pain and inflammation in affected individuals where diclofenac works by inhibiting the release of certain chemical messengers (responsible for pain and inflammation) in the brain and serratiopeptidase reduces inflammatory reaction by breaking down abnormal proteins at the site of inflammation thus providing relief from inflammation and pain in affected individuals.
What are the most common side effects of taking TOLPA D TABLET?
The most common side effects of taking TOLPA D TABLET are headache, dizziness, abdominal pain, indigestion, nausea, vomiting, and/or diarrhea. Consult your doctor if any of these symptoms worsen.
What happens if more dose of TOLPA D TABLET is taken than the required dose?
If you or anyone else accidentally take too much of TOLPA D TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose are headache, nausea, vomiting, epigastric pain, GI hemorrhage, diarrhea, dizziness, disorientation, excitation, coma, drowsiness, tinnitus, fainting, and/or convulsions.
Can TOLPA D TABLET be used during pregnancy?
No, TOLPA D TABLET is not recommended for use in pregnant women especially during third trimester stage. It is also not recommended for use in women planning for pregnancy. However, it can be used with caution during first and second trimester of pregnancy provided if it is clearly necessary. Consult your doctor before taking the medicine.
Article Information
Written By
DETAILS Written By Dr. Janet.C
Medical Content Writer
Reviewed By
Dr. Sankara Babu Gorle
Medical Expert
Last Updated
12 Jul 2024