TOFATAS Ointment 30gm

Atopic Dermatitis(Eczema) (68)Rx required

Key Information

Generic Name

Generic Name Tofacitinib 2 %

Manufacturer

Intas Pharmaceuticals Ltd

Country of Origin

India

Detailed Information

Introduction

INTRODUCTION ABOUT TOFATAS OINTMENTTOFATAS OINTMENT is used to manage mild to moderate atopic dermatitis (AD), such as dry, itchy, swollen, and red skin. It contains Tofacitinib, which belongs to the group of medicines called Janus Kinase Inhibitors. It suppresses an overactive immune system by inhibiting certain enzymes called Janus kinases (JAKs). Thus, TOFATAS OINTMENT blocks the production of pro-inflammatory substances (including cytokines) that contribute to the development of inflammation and other symptoms of atopic dermatitis. Apply TOFATAS OINTMENT to the affected area as directed by your doctor to get the most benefit. Prior to the initiation of this medicine, your doctor may order blood tests to understand and monitor your existing condition. TOFATAS OINTMENT is not recommended for use in pregnant women and breastfeeding women. Consult your doctor before using it. TOFATAS OINTMENT is not recommended for use if you have active tuberculosis (TB) or severe liver disease. Consult your doctor before using it. TOFATAS OINTMENT should be used with caution in patients with a history of chronic lung disease or in those who develop interstitial lung disease due to the increased risk of infections. Consult your doctor before using it. The safety and efficacy of TOFATAS OINTMENT in children are not established. Consult your child’s doctor for advice. The most common

Uses

OF TOFATAS OINTMENTIt is used to: manage mild to moderate atopic dermatitis

How It Works

TOFATAS OINTMENT suppresses an overactive immune system by inhibiting certain enzymes called Janus kinases (JAKs). Thus, TOFATAS OINTMENT blocks the production of pro-inflammatory substances (including cytokines) that contribute to the development of inflammation and other symptoms of atopic dermatitis.

Directions for Use

Apply TOFATAS OINTMENT as advised by your doctor. It is for external use only. Apply TOFATAS OINTMENT as a thin layer to the affected area as directed by your doctor to get the most benefit. Your doctor will decide the correct dose and duration of TOFATAS OINTMENT for you depending upon your age, body weight, and disease condition.

Side Effects

using TOFATAS OINTMENT are application site eczema, application site itching, and fever. Consult your doctor if any of the side effects worsen. USES OF TOFATAS OINTMENTIt is used to: manage mild to moderate atopic dermatitis HOW TOFATAS OINTMENT WORKSTOFATAS OINTMENT suppresses an overactive immune system by inhibiting certain enzymes called Janus kinases (JAKs). Thus, TOFATAS OINTMENT blocks the production of pro-inflammatory substances (including cytokines) that contribute to the development of inflammation and other symptoms of atopic dermatitis. DIRECTIONS FOR USEApply TOFATAS OINTMENT as advised by your doctor. It is for external use only. Apply TOFATAS OINTMENT as a thin layer to the affected area as directed by your doctor to get the most benefit. Your doctor will decide the correct dose and duration of TOFATAS OINTMENT for you depending upon your age, body weight, and disease condition. SIDE EFFECTS OF TOFATAS OINTMENTCOMMON Application site eczema Application site itching Fever RAREStop taking TOFATAS OINTMENT and contact your physician immediately if you experience any of the following side effects: Serious infection, an opportunistic infection, or sepsis Serious allergic reactions such as urticaria and angioedema Signs of myocardial infarction or stroke

Warnings & Precautions

& PRECAUTIONSPREGNANCYContraindicatedTOFATAS OINTMENT is not recommended for use by pregnant women. Women of childbearing potential should be advised to use effective contraception during treatment with TOFATAS OINTMENT and for at least 4 weeks after the last dose. Consult your doctor before using it. BREASTFEEDINGContraindicatedTOFATAS OINTMENT is not recommended for use by breastfeeding women. Consult your doctor before using it. DRIVING AND USING MACHINESSafeTOFATAS OINTMENT has no influence on the ability to drive or operate machinery. LIVERContraindicatedTOFATAS OINTMENT is not recommended for use if you have severe liver disease. Consult your doctor before using it. ALLERGYContraindicatedDo not use TOFATAS OINTMENT if you are allergic to tofacitinib or any of the other ingredients in this medicine. LUNGSConsult your doctorTOFATAS OINTMENT is not recommended for use if you have active tuberculosis (TB). It should be used with caution in patients with a history of chronic lung disease or in those who develop interstitial lung disease due to the increased risk of infections. Consult your doctor before using it. USE IN PEDIATRICSConsult your doctorThe safety and efficacy of TOFATAS OINTMENT in children are not established. Consult your child’s doctor for advice. OTHERSTOFATAS OINTMENT is not recommended for use if you: Have serious infections, such as sepsis, or opportunistic infections Have a low white blood cell count Have low levels of haemoglobin Before using TOFATAS OINTMENT, inform your doctor if you: Have a chronic or recurrent infection Have been exposed to tuberculosis History of a serious or an opportunistic infection Have resided or travelled in areas of endemic tuberculosis or endemic mycoses Have underlying conditions that may predispose to infections Have a decrease in white blood cell count Have herpes zoster (due to virus reactivation) Have an increased risk of thrombosis (blood clots)

Drug Interactions

SA. Drug-Drug interactions: Antifungals (Ex. ketoconazole, fluconazole) Anti-tubercular agent (Ex. rifampicin) Immunosuppressants (Ex. tacrolimus, ciclosporin) Live vaccines Overdosage: If you or anyone else accidentally swallows too much of TOFATAS OINTMENT, consult your doctor immediately or visit the nearby hospital. SYNOPSIS Drug : Tofacitinib Pharmacological Category : Janus Kinase Inhibitors Therapeutic Indication : Atopic dermatitis Dosage Forms : Tablet, Capsule, Gel, and Ointment MORE INFORMATIONSTORAGE Keep TOFATAS OINTMENT out of reach of children Store at room temperature not exceeding 30ºC. Do not freeze

Frequently Asked Questions

Common questions and answers about TOFATAS Ointment 30gm.

Q

What is TOFATAS OINTMENT used for?

A

TOFATAS OINTMENT is used to manage mild to moderate atopic dermatitis (AD) such as dry, itchy, swollen, and red skin. Consult your doctor before using it.

Q

How does TOFATAS OINTMENT work?

A

TOFATAS OINTMENT suppresses an overactive immune system by inhibiting certain enzymes called Janus kinases (JAKs). Thus, TOFATAS OINTMENT blocks the production of pro-inflammatory substances (including cytokines) that contribute to the development of inflammation and other symptoms of atopic dermatitis.

Q

How should I apply TOFATAS OINTMENT?

A

Apply TOFATAS OINTMENT as advised by your doctor. It is for external use only. Apply TOFATAS OINTMENT to the affected area as directed by your doctor to get the most benefit. Your doctor will decide the correct dose and duration of TOFATAS OINTMENT for you depending upon your age, body weight, and disease condition.

Q

Is TOFATAS OINTMENT safe during pregnancy?

A

TOFATAS OINTMENT is not recommended for use by pregnant women. Women of childbearing potential should be advised to use effective contraception during treatment with TOFATAS OINTMENT and for at least 4 weeks after the last dose. Consult your doctor before using it.

Q

Can TOFATAS OINTMENT be used with children?

A

The safety and efficacy of TOFATAS OINTMENT in children are not established. Consult your child’s doctor for advice.

Q

Can I use TOFATAS OINTMENT daily?

A

Apply a thin layer of TOFATAS OINTMENT twice daily to affected areas for 4 consecutive weeks or as directed by the physician. It is for topical use only. Tofacitinib ointment 2% w/w is not for ophthalmic, oral, or intravaginal use.

Q

What are the side effects of using TOFATAS OINTMENT?

A

The most common side effects of using TOFATAS OINTMENT are application site eczema, application site itching, and fever. Consult your doctor if any of the side effects worsen.

Q

Who should not use TOFATAS OINTMENT?

A

TOFATAS OINTMENT is not recommended for use if you have active tuberculosis (TB), severe liver disease, are allergic to Tofacitinib, have serious infections such as sepsis or opportunistic infections, have a low white blood cell count, or have low levels of haemoglobin. Consult your doctor before using it.

Q

What precautions must be taken while using TOFATAS OINTMENT?

A

Before using TOFATAS OINTMENT, inform your doctor if you have a history of chronic lung disease, interstitial lung disease, chronic or recurrent infection, have been exposed to tuberculosis, have a history of a serious or an opportunistic infection, or if you have resided or travelled in areas of endemic tuberculosis or endemic mycoses, have underlying conditions that may predispose to infections, a decrease in white blood cell count, herpes zoster (due to virus reactivation), or have an increased risk of thrombosis (blood clots).

Q

Can I use other medicines along with TOFATAS OINTMENT?

A

Before using TOFATAS OINTMENT, inform your doctor if you are taking prescription, non-prescription, or herbal medicines.

Article Information

DW

Written By

DETAILS Written By Dr. N. Sai Swaroop

Medical Content Writer

DS

Reviewed By

Dr. Sankara Babu Gorle

Medical Expert

Last Updated

21 Jun 2024

Tags

#atopic dermatitis(eczema) (68)#generic name tofacitinib 2 %