TOFASURE XR Tablet 10's

Arthritis (135)Rx required

Key Information

Generic Name

Generic Name Tofacitinib 11 mg

Manufacturer

Canixa Life Sciences Pvt Ltd

Variant

10 Tablet(s) in a Strip

Country of Origin

India

Detailed Information

Introduction

TOFASURE XR TABLET is used to manage inflammatory diseases such as rheumatoid arthritis, psoriatic arthritis, ulcerative colitis, and ankylosing spondylitis. TOFASURE XR TABLET is also used to manage polyarticular juvenile idiopathic arthritis and juvenile psoriatic arthritis, which cause pain and inflammation of joints in children. TOFASURE XR TABLET contains Tofacitinib, which belongs to the group of medicines called Antirheumatics. It prevents the body from responding to these substances called cytokines (which control the growth and activity of other immune system cells and blood cells). It also inhibits the inflammation process via a new pathway (Janus kinases). TOFASURE XR TABLET is used alone or together with other drugs, such as methotrexate. Take TOFASURE XR TABLET as advised by your physician. Swallow the medicine with a glass of water. It can also be crushed and taken with water. Do not chew the medicine. TOFASURE XR TABLET is not recommended for use in patients with severe liver diseases (including cirrhosis), bloodstream infections, or active tuberculosis. TOFASURE XR TABLET should be used with caution in patients who have an infection or a condition that increases their risk of infection (for example, diabetes, HIV/AIDS, or a weak immune system), chronic lung disease, tuberculosis, hepatitis B or C, liver, kidney, or heart diseases, cancer or are at risk of developing skin cancer, smoking habits, lactose intolerance, inflammation of the large intestine, stomach or intestine ulcers, blood pressure, high cholesterol, or are at risk of developing a blood clot, are planning to get vaccinated, or have undergone major surgery. TOFASURE XR TABLET should not be used by pregnant or breastfeeding women. TOFASURE XR TABLET should be used with caution in patients over the age of 65. The safety and effectiveness of TOFASURE XR TABLET in children under the age of two have not yet been established. Lung infection, sore throat, sinusitis, vomiting, nausea, diarrhea, indigestion, and headache are the most common

Uses

OF TOFASURE XR TABLETManages inflammatory conditions such as: Rheumatoid arthritis Psoriatic arthritis Ulcerative colitis Ankylosing spondylitis Polyarticular juvenile idiopathic arthritis Juvenile psoriatic arthritis

How It Works

TOFASURE XR TABLET helps in managing inflammatory diseases by modifying the immune system. It prevents the body from responding to these substances called cytokines (which control the growth and activity of other immune system cells and blood cells). It also inhibits the inflammation process via a new pathway (Janus kinases).

Directions for Use

Take TOFASURE XR TABLET as advised by your physician. Swallow the medicine with a glass of water. It can also be crushed and taken with water. Do not chew the medicine. Your doctor will decide the correct dose and duration of TOFASURE XR TABLET for you depending on your age, disease condition, and body weight.

Side Effects

TOFASURE XR TABLET. Ask for your doctor’s advice if any of these worsen or don’t improve. USES OF TOFASURE XR TABLETManages inflammatory conditions such as: Rheumatoid arthritis Psoriatic arthritis Ulcerative colitis Ankylosing spondylitis Polyarticular juvenile idiopathic arthritis Juvenile psoriatic arthritis HOW TOFASURE XR TABLET WORKSTOFASURE XR TABLET helps in managing inflammatory diseases by modifying the immune system. It prevents the body from responding to these substances called cytokines (which control the growth and activity of other immune system cells and blood cells). It also inhibits the inflammation process via a new pathway (Janus kinases). DIRECTIONS FOR USETake TOFASURE XR TABLET as advised by your physician. Swallow the medicine with a glass of water. It can also be crushed and taken with water. Do not chew the medicine. Your doctor will decide the correct dose and duration of TOFASURE XR TABLET for you depending on your age, disease condition, and body weight. SIDE EFFECTS OF TOFASURE XR TABLETCOMMON Lung infection such as pneumonia or bronchitis Shingles (herpes zoster) Nasopharyngitis (infections of the nose, throat, or windpipe) Influenza Sinusitis Urinary bladder infection Sore throat Signs of muscle problems Stomach pain (possibly due to inflammation of the stomach lining) Vomiting, nausea Diarrhoea Indigestion Anaemia Fever, fatigue Swelling of the feet and hands Headache High blood pressure Cough Rash UNCOMMON Tuberculosis Signs of kidney problems (blood creatinine increase) Skin infection, skin redness, itching Cold sores (tiny, painful blisters at the border of the lip) Low white blood cells Signs of liver problems (increase in liver enzymes) Increased cholesterol Weight gain Dehydration Muscle strain Pain in the muscles and joints; tendonitis (inflammation of tendons) Joint swelling and sprain Abnormal sensations Poor sleep Sinus congestion Shortness of breath or difficulty breathing Fatty liver Painful inflammation of small pockets in the lining of your intestine (diverticulitis) Viral infections: viral infections affecting the digestive tract Some types of skin cancers (non-melanoma types) Lung cancer RARE Blood infection (sepsis) Lymphoma (white blood cell cancer) Disseminated tuberculosis involving bones and other organs Other unusual infections Joint infections Stop taking TOFASURE XR TABLET and inform your doctor immediately if you experience any of the following side effects: Signs of serious infections such as fever and chills, cough, skin blisters, stomach pain, and persistent headaches Signs of ulcers or perforations in the stomach, such as fever, stomach or abdominal pain, blood in the stool, or unexplained changes in bowel habits Signs of allergic reactions such as chest tightness, wheezing, severe dizziness or lightheadedness, swelling of the lips, tongue, or throat, and hives (itching or skin rash) Signs of blood clots in the lungs or veins, such as sudden shortness of breath or difficulty breathing, leg pain or tenderness, chest pain or pain in the upper back, swelling of the leg or arm, redness or discolouration in the leg or arm Signs of a heart attack may include severe chest pain or tightness (that may spread to the arms, back, jaw, and neck), shortness of breath, cold sweat, lightheadedness, or sudden dizziness.

Warnings & Precautions

& PRECAUTIONSPREGNANCYContraindicatedTOFASURE XR TABLET is not recommended for use by pregnant women or women planning to have a baby. If you are a woman of childbearing age, you should use effective birth control during management and for at least 4 weeks after the last dose. Consult your doctor before taking it. BREASTFEEDINGContraindicatedTOFASURE XR TABLET is not recommended for use in breastfeeding women. Consult your doctor before taking it. DRIVING AND USING MACHINESSafeTOFASURE XR TABLET does not affect your ability to drive or use machines. KIDNEYUse with CautionTOFASURE XR TABLET should be taken with caution in patients with kidney disease. The dose will be adjusted by your doctor. Consult your doctor before taking it. LIVERConsult your doctorTOFASURE XR TABLET is not recommended in patients with severe liver problems such as cirrhosis (scarring of the liver). It should be used with caution in patients with other liver diseases, such as hepatitis B or hepatitis C. The dose will be adjusted by your doctor. Consult your doctor before taking it. ALLERGYContraindicatedDo not take TOFASURE XR TABLET if you are allergic to Tofacitinib or any other ingredients in this medicine. LUNGSConsult your doctorTOFASURE XR TABLET is not recommended for use in active tuberculosis. TOFASURE XR TABLET should be taken with caution in patients with chronic lung disease or a history of tuberculosis. Consult your doctor before taking it. HEART DISEASEUse with CautionTOFASURE XR TABLET should be taken with caution in patients with heart diseases such as heart attack and high blood pressure. Consult your doctor before taking it. USE IN PEDIATRICSConsult your doctorThe safety and effectiveness of TOFASURE XR TABLET in children below 2 years of age have not been established yet. Consult with your doctor before taking it. USE IN GERIATRICSUse with CautionTOFASURE XR TABLET should be used with caution in patients over the age of 65, as they may be at increased risk of infections, heart attacks, and some types of cancer. Consult with your doctor before taking it. OTHERSTOFASURE XR TABLET is not recommended for use if you have: Severe bloodstream infection Before taking TOFASURE XR TABLET, inform your doctor if you have: Infection, being managed for an infection or having symptoms of it (fever, sweating, chills, muscle aches, cough, shortness of breath, phlegm, weight loss, warm or red or painful sores, difficulty or painful swallowing, diarrhea or stomach pain, problems with urination, tiredness) Conditions that increase the chances of infection (Ex. diabetes, HIV/AIDS, or a weak immune system) Tendency of having infections or recurrent infections Cancer or at risk of developing cancer, especially skin cancer Habit of smoking Lactose intolerance Inflammation of the large intestine (diverticulitis) Stomach or intestine ulcers High cholesterol Risk of developing blood clots (seriously overweight, cancer, heart problems, diabetes) Plans for getting vaccinated Have undergone a major surgery

Drug Interactions

SA. Drug-Drug Interactions: Antibiotics (such as rifampicin) Antifungals (Ex. fluconazole, ketoconazole) Immunosuppressants (Ex. azathioprine, mercaptopurine, ciclosporin, and tacrolimus) Corticosteroids (such as prednisone) Overdosage: If you or anyone else accidentally takes too much TOFASURE XR TABLET, consult your doctor immediately or visit a nearby hospital. SYNOPSIS Drug : Tofacitinib Pharmacological Category : Janus kinase inhibitors Therapeutic Indication : Inflammatory diseases Dosage Forms : Tablet MORE INFORMATIONSTORAGE Keep TOFASURE XR TABLET out of reach of children Store below 30°C

Frequently Asked Questions

Common questions and answers about TOFASURE XR Tablet 10's.

Q

What is TOFASURE XR TABLET, and why is it prescribed?

A

TOFASURE XR TABLET contains tofacitinib, which belongs to the group of medicines called immunosuppressants. It is used to manage inflammatory diseases such as rheumatoid arthritis (chronic inflammatory diseases of the joints that cause pain and swelling), psoriatic arthritis (arthritis that affects people who have psoriasis), ulcerative colitis (inflammation and ulcers in the digestive tract), and ankylosing spondylitis (inflammatory disease that causes the bones in the spine to fuse). TOFASURE XR TABLET is also used to manage polyarticular juvenile idiopathic arthritis and juvenile psoriatic arthritis, which cause pain and inflammation of joints in children. TOFASURE XR TABLET is used together with drugs such as methotrexate when previous rheumatoid arthritis management was not sufficient or was not well tolerated.

Q

What should I know before starting to take TOFASURE XR TABLET?

A

TOFASURE XR TABLET can lower the ability of your immune system to fight infections. Do not start stating TOFASURE XR TABLET if you have any kind of infection, a history of infection, or are at risk of developing one. Consult with your doctor before taking TOFASURE XR TABLET.

Q

Can TOFASURE XR TABLET be taken by pregnant or breastfeeding women?

A

TOFASURE XR TABLET is not recommended for use by pregnant or breastfeeding women. If you are a woman of childbearing age, effective birth control methods must be used during management with TOFASURE XR TABLET and for at least 4 weeks after the last dose. Tell your doctor immediately if you become pregnant while taking TOFASURE XR TABLET. Consult your doctor before taking it.

Q

Is the TOFASURE XR TABLET used by children?

A

TOFASURE XR TABLET is used to manage polyarticular juvenile idiopathic arthritis and juvenile psoriatic arthritis, which cause pain and inflammation of joints in children over 2 years of age. Ask for your doctor’s advice before giving it to your child.

Q

Do I need to undergo routine diagnostic tests while taking TOFASURE XR TABLET?

A

Your doctor might check you regularly for the levels of white blood cells and red blood cells in your blood while you take TOFASURE XR TABLET. He must also check his cholesterol levels and liver and kidney functions regularly.

Q

How do I manage if I forget to take a dose of TOFASURE XR TABLET?

A

If you forgot to take a dose of TOFASURE XR TABLET, then do not take the missed dose between meals. Continue taking your medication as usual until your next scheduled dose and meal. Do not take a double dose of TOFASURE XR TABLET to make up for a forgotten dose. Consult your doctor for advice.

Q

Can TOFASURE XR TABLET be used safely on elderly patients?

A

Patients aged 65 years and older may be at increased risk of infections, heart attacks, and some types of cancer; therefore, TOFASURE XR TABLET should be used with caution in patients above the age of 65 years. Consult with your doctor before taking it.

Q

What does TOFASURE XR TABLET contain?

A

TOFASURE XR TABLET contains Tofacitinib, which belongs to the group of medicines called Antirheumatics.

Q

How does TOFASURE XR TABLET work?

A

TOFASURE XR TABLET helps in managing inflammatory diseases by modifying the immune system. It prevents the body from responding to these substances called cytokines (which control the growth and activity of other immune system cells and blood cells). It also inhibits the inflammation process via a new pathway (Janus kinases).

Q

What are the side effects of taking TOFASURE XR TABLET?

A

The most common side effects of taking TOFASURE XR TABLET are lung infection, sore throat, sinusitis, vomiting, nausea, diarrhea, indigestion, and headache. Consult your doctor if any of the side effects worsen.

Article Information

DW

Written By

DETAILS Written By Dr. N. Sai Swaroop

Medical Content Writer

DS

Reviewed By

Dr. Sankara Babu Gorle

Medical Expert

Last Updated

26 Jun 2024

Tags

#arthritis (135)#generic name tofacitinib 11 mg