TOFASHINE 5mg Tablet 10's

Rheumatoid Arthritis (48)Rx required

Key Information

Generic Name

Generic Name Tofacitinib 5 mg

Manufacturer

Sun Pharmaceutical Industries Ltd

Variant

10 Tablet(s) in a Strip

Country of Origin

India

Detailed Information

Introduction

TOFASHINE 5MG TABLET contains Tofacitinib, which belongs to the group of medicines called Antirheumatics. It is used to manage inflammatory diseases such as rheumatoid arthritis (chronic inflammatory diseases affecting the joints, causing pain and swelling), psoriatic arthritis (an arthritic condition that occurs in an individual with psoriasis), ulcerative colitis (ulcerative inflammation of the digestive tract) and ankylosing spondylitis (fusion of bones in the spine). TOFASHINE 5MG TABLET is also used to manage polyarticular juvenile idiopathic arthritis and juvenile psoriatic arthritis, which cause pain and inflammation of joints in children. TOFASHINE 5MG TABLET is used alone or together with other drugs, such as methotrexate. TOFASHINE 5MG TABLET is not recommended for use in patients with severe liver diseases (including cirrhosis), bloodstream infections or active tuberculosis. TOFASHINE 5MG TABLET should be used with caution in patients who have an infection or a condition that increases their risk of infection (for example, diabetes, HIV/AIDS or a weak immune system), chronic lung disease, tuberculosis, hepatitis B or C, liver, kidney or heart diseases, cancer or are at risk of developing skin cancer, smoking habits, lactose intolerance, inflammation of the large intestine, stomach or intestine ulcers, blood pressure, high cholesterol or at risk of developing a blood clot, are planning to get vaccinated, have undergone major surgery. TOFASHINE 5MG TABLET should not be used by pregnant or breastfeeding women. TOFASHINE 5MG TABLET should be used with caution in patients over the age of 65. The safety and effectiveness of TOFASHINE 5MG TABLET in children under the age of two have not yet been established. Lung infection, sore throat, sinusitis, vomiting, nausea, diarrhoea, indigestion and headache are the most common

Uses

OF TOFASHINE 5MG TABLETManages inflammatory conditions such as: rheumatoid arthritis psoriatic arthritis ulcerative colitis ankylosing spondylitis polyarticular juvenile idiopathic arthritis juvenile psoriatic arthritis

How It Works

TOFASHINE 5MG TABLET helps in managing inflammatory diseases by modifying the immune system. It manages the body from responding to these substances called cytokines (controls growth and activity of other immune system cells and blood cells). It also inhibits the inflammation process via a new pathway (Janus kinases).

Directions for Use

Take TOFASHINE 5MG TABLET as advised by your physician. Swallow the medicine with a glass of water. It can also be crushed and taken with water. Do not chew the medicine. Your doctor will decide the correct dose and duration of TOFASHINE 5MG TABLET for you depending on your age, disease condition and body weight.

Side Effects

TOFASHINE 5MG TABLET. Ask for your doctor’s advice if any of these worsen or don’t improve. USES OF TOFASHINE 5MG TABLETManages inflammatory conditions such as: rheumatoid arthritis psoriatic arthritis ulcerative colitis ankylosing spondylitis polyarticular juvenile idiopathic arthritis juvenile psoriatic arthritis HOW TOFASHINE 5MG TABLET WORKSTOFASHINE 5MG TABLET helps in managing inflammatory diseases by modifying the immune system. It manages the body from responding to these substances called cytokines (controls growth and activity of other immune system cells and blood cells). It also inhibits the inflammation process via a new pathway (Janus kinases). DIRECTIONS FOR USETake TOFASHINE 5MG TABLET as advised by your physician. Swallow the medicine with a glass of water. It can also be crushed and taken with water. Do not chew the medicine. Your doctor will decide the correct dose and duration of TOFASHINE 5MG TABLET for you depending on your age, disease condition and body weight. SIDE EFFECTS OF TOFASHINE 5MG TABLETCOMMON lung infection such as pneumonia or bronchitis shingles (herpes zoster) nasopharyngitis (infections of the nose, throat or windpipe) influenza sinusitis urinary bladder infection sore throat signs of muscle problems stomach pain (possibly due to inflammation of the stomach lining) vomiting, nausea diarrhoea indigestion anaemia fever, fatigue swelling of the feet and hands headache high blood pressure cough rash UNCOMMON tuberculosis signs of kidney problems (blood creatinine increase) skin infection, skin redness, itching cold sores (tiny painful blisters at the border of the lip) low white blood cells signs of liver problems (increase in liver enzyme,) increased cholesterol weight gain dehydration muscle strain pain in the muscles and joints, tendonitis (inflammation of tendons) joint swelling and sprain abnormal sensations poor sleep sinus congestion shortness of breath or difficulty breathing fatty liver painful inflammation of small pockets in the lining of your intestine (diverticulitis) viral infections, viral infections affecting the digestive tract some types of skin cancers (non-melanoma types) lung cancer RARE blood infection (sepsis) lymphoma (white blood cell cancer) disseminated tuberculosis involving bones and other organs other unusual infections joint infections Stop taking TOFASHINE 5MG TABLET and inform your doctor immediately if you experience any of the following side effects: signs of serious infections such as fever and chills, cough, skin blisters, stomach pain, persistent headaches signs of ulcers or perforations in the stomach such as fever, stomach or abdominal pain, blood in the stool, unexplained changes in bowel habits signs of allergic reactions such as chest tightness, wheezing, severe dizziness or light-headedness, swelling of the lips, tongue or throat, hives (itching or skin rash) signs of blood clots in lungs or veins such as sudden shortness of breath or difficulty breathing, leg pain or tenderness, chest pain or pain in the upper back, swelling of the leg or arm, redness or discolouration in the leg or arm signs of a heart attack such as severe chest pain or tightness (that may spread to arms, back, jaw, neck), shortness of breath, cold sweat, light-headedness or sudden dizziness

Warnings & Precautions

& PRECAUTIONSPREGNANCYTOFASHINE 5MG TABLET is not recommended for use in pregnant women or women planning to have a baby. If you are a woman of childbearing age, you should use effective birth control during management and for at least 4 weeks after the last dose. Consult your doctor before taking it. BREASTFEEDINGTOFASHINE 5MG TABLET is not recommended for use in breastfeeding women. Consult your doctor before taking it. DRIVING AND USING MACHINESTOFASHINE 5MG TABLET does not affect your ability to drive or use machines. KIDNEYTOFASHINE 5MG TABLET should be taken with caution in patients with kidney disease. The dose will be adjusted by your doctor Consult your doctor before taking it. LIVERTOFASHINE 5MG TABLET is not recommended in patients with severe liver problems such as cirrhosis (scarring of the liver). It should be used with caution in patients having other liver diseases such as hepatitis B or hepatitis C. Dose will be adjusted by your doctor. Consult your doctor before taking it. ALLERGYDo not take TOFASHINE 5MG TABLET if you are allergic to Tofacitinib or any other ingredients of this medicine. LUNGSTOFASHINE 5MG TABLET is not recommended for use in active tuberculosis. TOFASHINE 5MG TABLET should be taken with caution in patients with chronic lung disease or a history of tuberculosis. Consult your doctor before taking it. HEART DISEASETOFASHINE 5MG TABLET should be taken with caution in patients with heart diseases such as heart attack and high blood pressure. Consult your doctor before taking it. OTHERSTOFASHINE 5MG TABLET is not recommended for use if you have: severe bloodstream infection Before taking TOFASHINE 5MG TABLET inform your doctor if you have: infection, being managed for an infection or having symptoms of it (fever, sweating, chills, muscle aches, cough, shortness of breath, phlegm, weight loss, warm or red or painful sores, difficulty or painful swallowing, diarrhoea or stomach pain, problems with urination, tiredness) conditions that increase the chances of infections (Ex. diabetes, HIV/AIDS or a weak immune system) tendency of having infections/ recurrent infections cancer or at risk of developing cancer, especially skin cancer habit of smoking lactose intolerance inflammation of the large intestine (diverticulitis) stomach or intestine ulcers high cholesterol risk of developing blood clots (seriously overweight, cancer, heart problems, diabetes) plans for getting vaccinated have undergone a major surgery Use in paediatrics: The safety and effectiveness of TOFASHINE 5MG TABLET in children below 2 years of age have not been established yet. Consult with your doctor before taking it. Use in geriatrics: TOFASHINE 5MG TABLET should be used with caution in patients above the age of 65 years of age as they may be at increased risk of infections, heart attack and some types of cancer. Consult with your doctor before taking it.

Drug Interactions

SA, Drug-Drug Interactions: Before taking TOFASHINE 5MG TABLET Inform your physician if you are taking any of the following medicines: antibiotics such as rifampicin (used in managing bacterial infections) fluconazole, ketoconazole (used to manage fungal infections) azathioprine, mercaptopurine, ciclosporin, tacrolimus (medicines that depress the immune system) corticosteroids such as prednisone (used in managing pain and inflammation) Overdosage: If you or anyone else accidentally take too much of TOFASHINE 5MG TABLET, consult your doctor immediately or visit the nearby hospital. SYNOPSIS Drug : Tofacitinib Pharmacological Category : Janus Kinase Inhibitors Therapeutic Indication : Inflammatory diseases Dosage Forms : Tablet MORE INFORMATION Keep TOFASHINE 5MG TABLET out of reach from children Store at below 30°C

Article Information

DW

Written By

DETAILS Written By Dr. Dhivakaran R

Medical Content Writer

DS

Reviewed By

Dr. Sankara Babu Gorle

Medical Expert

Last Updated

29 Nov 2022

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#rheumatoid arthritis (48)#generic name tofacitinib 5 mg