TIGEMAC 90 Tablet 10's
Key Information
Generic Name
Generic Name Ticagrelor 90 mg
Manufacturer
Macleods Pharmaceuticals Pvt Ltd
Variant
10 Tablet(s) in a Strip
Country of Origin
India
Detailed Information
Introduction
TIGEMAC 90 TABLET contains ticagrelor which belongs to the group of medicines called antiplatelet agents. It is used to reduce the rate of cardiovascular death, myocardial infarction and stroke in patients with acute coronary syndrome (ACS) or a history of myocardial infarction. It also reduces the rate of stent thrombosis in patients who have been stented for management of ACS. Ticagrelor stops clumping of blood cells called platelets, which is responsible for clot formation in diseased blood vessels of heart and brain and thus reduces the chances of a blood clot formation. It can be taken with or without food. Avoid concomitant use of ticagrelor and other oral anticoagulants like heparin or warfarin, as it may increase the risk of
Uses
OF TIGEMAC 90 TABLET Used to reduce the rate of cardiovascular death, myocardial infarction and stroke in patients with acute coronary syndrome (ACS) or a history of myocardial infarction
How It Works
Ticagrelor is a potent P2Y12 receptor antagonist. In diseased blood vessels, platelets can form thrombus (blood clot) by binding to the arterial surface. Activated platelets produces ADP3 which binds to P2Y12 receptor and propagates thrombus formation. Ticagrelor reversibly binds to P2Y12 receptor instead of ADP3 and prevents the signal transduction and platelet activation, that can lead to blood clot formation.
Directions for Use
Take this medicine as directed by your physician. It can be taken with or without food. Your doctor will decide the correct dose for you depending upon your condition. Swallow the medicine with a glass of water. Continue to take this medicine, as long as your doctor tells you to do so, to obtain better results.
Side Effects
taking this medicine are bleeding and bruising. USES OF TIGEMAC 90 TABLET Used to reduce the rate of cardiovascular death, myocardial infarction and stroke in patients with acute coronary syndrome (ACS) or a history of myocardial infarction HOW TIGEMAC 90 TABLET WORKSTicagrelor is a potent P2Y12 receptor antagonist. In diseased blood vessels, platelets can form thrombus (blood clot) by binding to the arterial surface. Activated platelets produces ADP3 which binds to P2Y12 receptor and propagates thrombus formation. Ticagrelor reversibly binds to P2Y12 receptor instead of ADP3 and prevents the signal transduction and platelet activation, that can lead to blood clot formation. DIRECTIONS FOR USETake this medicine as directed by your physician. It can be taken with or without food. Your doctor will decide the correct dose for you depending upon your condition. Swallow the medicine with a glass of water. Continue to take this medicine, as long as your doctor tells you to do so, to obtain better results. SIDE EFFECTS OF TIGEMAC 90 TABLETSERIOUS Signs of stroke (such as headache, feeling dizzy, sudden numbness of arm, leg or face, especially if only on one side of the body, confusion, difficulty in speaking, lack of co-ordination) Unexpected bleeding Pink, red or brown urine Vomiting blood clots Red or black stools Fainting (syncope) Thrombotic Thrombocytopenic Purpura (such as fever and purplish spots on skin or in mouth, with or without yellowing of skin or eyes, unexplained extreme tiredness or confusion) COMMON Shortness of breath Bleeding and bruising Headache, feeling dizzy Diarrhea, indigestion or constipation Nausea Skin rash or itching Gout (severe pain and swelling in joints) Low blood pressure Bleeding in the nose, stomach lining or gums Bleeding after surgery or from cuts
Warnings & Precautions
& PRECAUTIONSPREGNANCYMonitoring requiredTIGEMAC 90 TABLET is not recommended for use in pregnant women unless necessary. Discuss the risks and benefits with your doctor. BREASTFEEDINGMonitoring requiredTIGEMAC 90 TABLET is not recommended for use in breastfeeding women unless necessary. Discuss the risks and benefits with your doctor. DRIVING AND USING MACHINESUse with CautionDo not drive or operate any machines if your ability is affected by this medicine. ALCOHOLConsult your doctorAvoid consumption of alcohol while taking this medicine. LIVERContraindicatedDo not take TIGEMAC 90 TABLET if you are suffering from severe liver disease. Consult your doctor for advice. ALLERGYContraindicatedDo not take this medicine if you are allergic to Ticagrelor. LUNGSUse with CautionTIGEMAC 90 TABLET should be taken with caution in patients with asthma or other lung problems or breathing difficulties. Consult your doctor for advice. HEART DISEASEUse with CautionTIGEMAC 90 TABLET should be taken with caution in patients with abnormal heart rate. Consult your doctor for advice. OTHERSTalk to your doctor before taking this medicine, if you: Have a recent serious injury, recent surgery, recent bleeding from your stomach or gut or any other bleeding disorders Suffer from hyperuricemia (increased uric acid levels in blood)
Drug Interactions
STalk to your doctor, if you are taking, Other oral anticoagulants (e.g. heparin, warfarin) Medicines used to manage high cholesterol levels (e.g. simvastatin or lovastatin) Medicines used to manage epilepsy (e.g. phenytoin, carbamazepine and phenobarbital) Medicines used to manage depression (e.g. paroxetine, nefazodone, sertraline and citalopram) Medicines used to manage heart problems like heart failure (e.g. digoxin), abnormal heart rate (e.g. quinidine and diltiazem) or high blood pressure (e.g. propranolol, verapamil, captopril) Non-steroidal anti-inflammatory drugs (used to manage pain) e.g. ibuprofen and naproxen Rifampicin (used to manage tuberculosis) Cyclosporine (used to avoid graft rejection) Morphine and other opioids (used to manage severe pain) Ketoconazole (used to manage fungal infections) Clarithromycin (used to manage bacterial infections) Ritonavir and atazanavir (used to manage HIV infection) Cisapride (used to manage heartburn) Ergot alkaloids (used to manage migraine headaches) SYNOPSIS Drug : Ticagrelor Pharmacological Category : Antiplatelet agent, P2Y12 receptor antagonist Therapeutic Indication : Heart attack and stroke Dosage Forms : Tablet MORE INFORMATIONSTORAGE Store at room temperature Keep out of reach of children
Frequently Asked Questions
Common questions and answers about TIGEMAC 90 Tablet 10's.
Can TIGEMAC 90 TABLET be crushed?
Yes. If you feel difficulty in swallowing this medicine, you can crush it and mix with half glass of water and drink it.
Can TIGEMAC 90 TABLET cause shortness of breath?
Yes. This medicine may sometime cause shortness of breath in some individuals. Contact your doctor for advice.
Article Information
Written By
DETAILS Written By Dr. Janet.C
Medical Content Writer
Reviewed By
Dr. Sankara Babu Gorle
Medical Expert
Last Updated
08 Jul 2024