Tidomet Plus Tablet 10'S

Parkinsonism (115)Rx required

Key Information

Generic Name

Generic Name Carbidopa 25 mg+Levodopa 100 mg

Manufacturer

Torrent Pharmaceuticals Ltd

Variant

10 Tablet(s) in a Strip

Country of Origin

India

Detailed Information

Introduction

TIDOMET PLUS TABLET is a combination of Carbidopa and Levodopa which belongs to the group of medicines called Antiparkinsonian drugs. It is used to improve the signs of Parkinsonism. Parkinsonism is a long-term illness caused due to loss of nerve cells in the part of the brain which is responsible for producing dopamine. Dopamine is a chemical messenger that controls body balance and movements. Symptoms of parkinsonism include slow and unsteady movements, muscle tightness, shaking or trembling, difficulty in walking, balance and coordination. TIDOMET PLUS TABLET must be used with caution among patients having any form of glaucoma (increased pressure in the eyes), as it can lead to further damage to the eye. TIDOMET PLUS TABLET is not recommended for use in women who are pregnant or breastfeeding, including children and adolescents (aged below 18 years). It is important for caregivers to notice and report doctor immediately that if the patient develops any addictive symptoms like craving for large doses of TIDOMET PLUS TABLET, unusual behavior, gambling, excessive eating or spending, an abnormally high sex drive or any other activities that could harm themselves or others. Try to avoid eating a heavy meal that includes a lot of protein (such as beef, pork, cheese, fish and eggs) while taking TIDOMET PLUS TABLET, as it may interfere with its absorption. The common

Uses

OF TIDOMET PLUS TABLET Used to improve the signs of Parkinsonism

How It Works

TIDOMET PLUS TABLET effectively controls the signs of parkinsonism, where levodopa acts by converting itself into a substance called dopamine (a chemical messenger that controls body movement) and carbidopa acts by managing the breakdown of levodopa out

Directions for Use

Take TIDOMET PLUS TABLET as advised by your physician. Swallow the medicine as a whole and do not crush or chew the medicine. Continue to take TIDOMET PLUS TABLET unless your doctor tells you to stop because sudden withdrawal of TIDOMET PLUS TABLET can cause symptoms like mental changes, fever and muscle tightness. Your doctor will decide the correct dose and duration of TIDOMET PLUS TABLET for you depending upon your age, body weight and disease condition.

Side Effects

taking TIDOMET PLUS TABLET are nausea, vomiting, abnormal muscle movements, loss of appetite, dry mouth, bitter taste and tiredness. Consult your doctor if any of the side effects worsen. USES OF TIDOMET PLUS TABLET Used to improve the signs of Parkinsonism HOW TIDOMET PLUS TABLET WORKSTIDOMET PLUS TABLET effectively controls the signs of parkinsonism, where levodopa acts by converting itself into a substance called dopamine (a chemical messenger that controls body movement) and carbidopa acts by managing the breakdown of levodopa outside the brain, thereby allowing greater proportion of levodopa to enter the brain. Collectively they supplement the brain with sufficient dopamine levels which ultimately results in improving the signs of parkinsonism. DIRECTIONS FOR USETake TIDOMET PLUS TABLET as advised by your physician. Swallow the medicine as a whole and do not crush or chew the medicine. Continue to take TIDOMET PLUS TABLET unless your doctor tells you to stop because sudden withdrawal of TIDOMET PLUS TABLET can cause symptoms like mental changes, fever and muscle tightness. Your doctor will decide the correct dose and duration of TIDOMET PLUS TABLET for you depending upon your age, body weight and disease condition. SIDE EFFECTS OF TIDOMET PLUS TABLETCOMMON abnormal body movements (dyskinesia, chorea, dystonia) nausea, vomiting, dry mouth, bitter taste loss of appetite low blood pressure while standing up from sitting or lying position (orthostatic hypotension), fainting confusion, dizziness, nightmares, drowsiness, tiredness, sleeplessness feeling euphoria (an extremely strong feeling of happiness) UNCOMMON weight loss or weight gain difficulty in speaking or making abnormal sounds while speaking hoarseness, chest pain constipation, diarrhea, bloating increased saliva secretion, difficulties in swallowing fluid accumulation muscle spasms, loss of strength dark urine weakness hot flushes RARE excitement, anxiety, disorientation headache numbness, tingling or prickling sensation, fits blurred vision breathlessness, abnormal breathing patterns indigestion with fullness in upper abdomen or pain, heartburn urinary retention, involuntary passing of urine, persistent erection Stop taking TIDOMET PLUS TABLET and contact your doctor immediately if you experience any of the following side effects: signs of allergic reactions (such as skin rash, itching, swelling of your face, lips, tongue or throat, which may cause difficulty in breathing or swallowing) chest pain, uneven heartbeat or palpitations signs of bleeding in the stomach which may be shown as blood in faeces or darkened faeces signs of low blood counts (such as pale skin, fever, tiredness, sore throat or mild bruising and prolonged bleeding after injury) signs of neuroleptic malignant syndrome (muscle stiffness with high fever, sweating, increased salivation, inability to sit still, impaired consciousness) mental changes including hallucinations, delusions and depression fits (convulsions)

Warnings & Precautions

& PRECAUTIONSPREGNANCYTIDOMET PLUS TABLET is not recommended for use in pregnant women and in women who think that they might be pregnant. Consult your doctor before taking it. BREASTFEEDINGTIDOMET PLUS TABLET is not recommended for use in breastfeeding women. Consult your doctor before taking it. DRIVING AND USING MACHINESDo not drive or operate any heavy tools or machines, as TIDOMET PLUS TABLET may cause sudden sleep attacks or can make you feel sleepy suddenly. ALCOHOLAvoid consumption of alcohol while taking TIDOMET PLUS TABLET, as it could make you feel dizzier or drowsier. KIDNEYTIDOMET PLUS TABLET should be taken with caution among patients who have or had any kidney diseases in the past. Consult your doctor before taking it. LIVERTIDOMET PLUS TABLET should be taken with caution among patients who have or had any liver diseases in the past. Consult your doctor before taking it. ALLERGYTalk to your doctor if you are allergic to Levodopa or Carbidopa. HEART DISEASETIDOMET PLUS TABLET should be taken with caution among patients with heart disease (such as previous history of heart attack, heartbeat problems, circulation or breathing problems). Consult your doctor before taking it. OTHERSTIDOMET PLUS TABLET is not recommended for use in patients who: have ever had any forms of skin cancer have any unusual moles in the skin that has not yet been examined by the doctor have narrow-angle glaucoma (increased pressure in the eye) have a severe mental disorder (Ex. severe panic disorder, psychosis, severe depression, bipolar disorder) Before taking TIDOMET PLUS TABLET, inform your physician if you: have a history of fits (epilepsy) have had an ulcer in the stomach have vomited blood have any hormonal problems have had depression or any other similar mental problems have chronic wide-angle glaucoma (a painless eye condition that can affect your vision) feel sleepy or having sudden sleep attacks (Ex. Narcolepsy) are due to have a surgery are due to have a blood/urine test Use in pediatrics: TIDOMET PLUS TABLET is generally not recommended for use in children and adolescents (aged below 18 years). However, consult your child’s doctor for advice. Use in geriatrics: TIDOMET PLUS TABLET is considered safe for use in elderly patients (aged 65 years or above). However, proper dose adjustment and careful monitoring is required in such patients.

Drug Interactions

SA. Drug-Drug interactions: Before taking TIDOMET PLUS TABLET, inform your doctor, if you are taking any of the following medicines: medicines used to manage depression (such as isocarboxazid, phenelzine, selegiline, tranylcypromine) medicines used to manage tuberculosis (Ex. rifampicin, isoniazid) medicines used to manage high blood pressure (Ex. atenolol, propranolol, captopril, enalapril, olmesartan, telmisartan) medicines used to manage epilepsy (Ex. carbamazepine, valproic acid, phenytoin) medicines used to manage involuntary movements (such as ataxia, dystonia, myoclonus, tardive dyskinesia) Ex. fluphenazine, haloperidol, chlorpromazine or thioridazine medicines used to manage iron deficiency (Ex. ferrous fumarate, iron isomaltoside) medicines that can reduce muscle stiffness, strain or spasms (such as trihexyphenidyl, orphenadrine, benzatropine and procyclidine) papaverine (a medicine used to manage impotence in men) B. Drug-Food interaction: Try to avoid eating a heavy meal that includes a lot of protein (such as beef, pork, fish and eggs) while taking TIDOMET PLUS TABLET, as it may interfere with its absorption. Overdosage: If you or anyone else accidentally take too much of TIDOMET PLUS TABLET, contact your doctor immediately or go to a hospital straight away. SYNOPSIS Drug : Carbidopa, Levodopa Pharmacological Category : Dopamine agonists, Decarboxylase inhibitors Therapeutic Indication : Parkinsonism Dosage Forms : Tablet MORE INFORMATION Keep TIDOMET PLUS TABLET out of reach of children Store at room temperature

Article Information

I(

Written By

ity (HPRA). [Revised in October 2018] [Accessed on 21st March 2022] https://www.hpra.ie/img/uploaded/swedocuments/a48b3e79-0aae-4c3d-b727-a4272f22fc16.pdf 8. Torrent Pharmaceuticals Ltd. Tidomet Forte (Carbidopa 25mg and Levodopa 250 mg tablets). [Revised in June 2018]. [Accessed on 21st March 2022] https://www.torrentian.com/pisheet/Upload/PI_Sheet/542.pdf AUTHOR DETAILS Written By Dr. R. Dinesh John Rajkumar

Medical Content Writer

DS

Reviewed By

Dr. Sankara Babu Gorle

Medical Expert

Last Updated

09 Dec 2022

Tags

#parkinsonism (115)#generic name carbidopa 25 mg+levodopa 100 mg