Temodal 250mg Capsule 5'S
Key Information
Generic Name
Generic Name Temozolomide 250 mg
Manufacturer
Msd Pharmaceuticals Pvt Ltd
Variant
5 Capsule(s) in a Strip
Country of Origin
India
Detailed Information
Introduction
INTRODUCTION ABOUT TEMODAL 250MG CAPSULETEMODAL 250MG CAPSULE contains Temozolomide, which belongs to the group of medicines called Antineoplastic agents. It is used for specific forms of brain tumours in adults with newly diagnosed glioblastoma multiforme, which is used first together with radiotherapy as a concomitant phase of therapy and then used alone as a monotherapy. It is also used in children (above 3 years) and adults to manage malignant gliomas, such as glioblastoma multiforme or anaplastic astrocytoma, if they return or get worse after standard management. Glioblastoma multiforme is an aggressive type of cancer that affects the brain or spinal cord and is generally characterized by symptoms such as headache, nausea, drowsiness, blurred vision, personality changes, and seizures. Along with this management, your doctor might advise you to take liver function tests to assess the hepatotoxicity and function of your liver. Before taking TEMODAL 250MG CAPSULE, inform your doctor if you have or ever had a hepatitis B infection (serious liver infection). TEMODAL 250MG CAPSULE is not recommended for use if you have certain kinds of blood cells that are severely reduced, such as white blood cells and platelet count. TEMODAL 250MG CAPSULE should be used with caution during pregnancy only if it is clearly necessary and not recommended for use in breastfeeding women. It is not recommended for use in children below 3 years of age and should be used with caution in children and adolescents (from 3 to 18 years of age). Consult your doctor before taking TEMODAL 250MG CAPSULE. The most common
Uses
OF TEMODAL 250MG CAPSULEIt is used for: Specific forms of brain tumours in newly diagnosed glioblastoma multiforme (in adults) Malignant glioma, such as glioblastoma multiforme or anaplastic astrocytoma (in adults and children)
How It Works
TEMODAL 250MG CAPSULE works by damaging the genetic material (DNA and RNA) of the cancer cells in
Directions for Use
Take TEMODAL 250MG CAPSULE as advised by your physician. Swallow TEMODAL 250MG CAPSULE with a glass of water and do not chew or crush the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight, and disease condition.
Side Effects
taking TEMODAL 250MG CAPSULE are loss of appetite, difficulty while speaking, headache, vomiting, nausea, diarrhea, and constipation. Consult and inform your doctor if any of these symptoms get worse. USES OF TEMODAL 250MG CAPSULEIt is used for: Specific forms of brain tumours in newly diagnosed glioblastoma multiforme (in adults) Malignant glioma, such as glioblastoma multiforme or anaplastic astrocytoma (in adults and children) HOW TEMODAL 250MG CAPSULE WORKSTEMODAL 250MG CAPSULE works by damaging the genetic material (DNA and RNA) of the cancer cells inside the brain cells and works against the cell growth and multiplication. DIRECTIONS FOR USETake TEMODAL 250MG CAPSULE as advised by your physician. Swallow TEMODAL 250MG CAPSULE with a glass of water and do not chew or crush the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight, and disease condition. SIDE EFFECTS OF TEMODAL 250MG CAPSULECOMMON Loss of appetite Difficulty while speaking Headache Vomiting, nausea Diarrhea Constipation Rash Hair loss Tiredness Infections Feeling sick, extreme tiredness, loss of appetite (signs of neutropenia) Fever, cough, runny nose (signs of lymphopenia) Prolonged cuts, bleeding from gums, blood in urine (signs of thrombocytopenia) Allergic reactions Memory impairment Depression, anxiety, confusion, sleeplessness Difficulty concentrating Dizziness Visual disturbances Deafness, ringing in the ears, earache Blood clot in the lung or legs High blood pressure Shortness of breath Bronchitis Cough and cold Inflammation of sinuses Stomach or abdominal pain Dry skin, itching Muscle damage, muscle aches and pain, muscle weakness Joint and back pain Frequent urination Fever Flu-like symptoms such as chills, cough, fever, and muscle aches Pain Fluid retention Weight gain or loss Radiation injury such as weakness, hair loss, and bloody vomit UNCOMMON New or reactivated cytomegalovirus infections such as chickenpox, herpes simplex Signs of reactivated hepatitis B virus infections such as abdominal pain, dark urine, fever, and joint pain Secondary cancers, including leukemia (blood cancer) Reduced blood cell counts, such as pancytopenia Red spots under the skin Signs of diabetes insipidus Piles Dry mouth Blisters on body or in mouth Skin peeling, skin eruption, painful reddening of the skin, severe rash with skin swelling Increased sensitivity to sunlight Urticaria (red, itchy skin) Increased sweating Change in skin colour Vaginal bleeding or irritation Absent or heavy menstrual periods Breast pain Sexual impotence Shivering Stop taking TEMODAL 250MG CAPSULE and contact your doctor if you experience any of the following side effects: Signs of a severe allergic (hypersensitive) reaction such as itchy red skin, wheezing, or other breathing difficulty Uncontrolled bleeding Seizures (fits) Fever and symptoms of infections such as cough, chills, sweat Chills Severe headache
Warnings & Precautions
& PRECAUTIONSPREGNANCYMonitoring requiredTEMODAL 250MG CAPSULE should be used in pregnant women only if it is clearly necessary. Women with childbearing potential should use effective contraceptive precautions, which should be continued for at least 6 months following the completion of> management. Consult your doctor before taking TEMODAL 250MG CAPSULE. BREASTFEEDINGContraindicatedTEMODAL 250MG CAPSULE is not recommended for use in breastfeeding women. Consult your doctor before taking TEMODAL 250MG CAPSULE. DRIVING AND USING MACHINESContraindicatedTEMODAL 250MG CAPSULE may cause tiredness or sleepiness. If you experience any such effects, avoid driving and using machines. Consult your doctor before taking TEMODAL 250MG CAPSULE. KIDNEYUse with CautionTEMODAL 250MG CAPSULE should be used with caution in patients with kidney problems such as severe renal impairment. Consult your doctor for advice before taking TEMODAL 250MG CAPSULE. LIVERUse with CautionTEMODAL 250MG CAPSULE should be used with caution in patients with mild, moderate, and severe hepatic impairment. Consult your doctor for advice before taking TEMODAL 250MG CAPSULE. ALLERGYContraindicatedDo not take TEMODAL 250MG CAPSULE if you are allergic to Temozolomide or any of the other ingredients of this medicine. LUNGSUse with CautionTEMODAL 250MG CAPSULE should be used with caution in patients with lung disease such as pneumocystis jirovecii pneumonia (serious fungal infection of lungs). Consult your doctor before taking TEMODAL 250MG CAPSULE. USE IN PEDIATRICSContraindicatedTEMODAL 250MG CAPSULE is not recommended for use in children below 3 years of age. There is limited information in patients over 3 years of age who have taken TEMODAL 250MG CAPSULE. Consult your doctor before taking TEMODAL 250MG CAPSULE. USE IN GERIATRICSUse with CautionTEMODAL 250MG CAPSULE should be used with caution in elderly patients (aged 70 years or above). Consult your doctor before taking TEMODAL 250MG CAPSULE. OTHERSTEMODAL 250MG CAPSULE is not recommended for use if you: Have certain kinds of blood cells that are severely reduced, such as white blood cells and platelet count Before taking TEMODAL 250MG CAPSULE, inform your doctor if you: Have signs of anemia (low red blood cell count) Have signs of low platelet count Have a risk of other changes in blood cells, such as leukemia (blood cancer)
Drug Interactions
SA. Drug-Drug Interactions: Before taking TEMODAL 250MG CAPSULE, inform your doctor if you are taking any of the following medicines: Dacarbazine (used for cancer of the lymph system and malignant melanoma) Overdosage: If you or anyone else accidentally takes too much of TEMODAL 250MG CAPSULE, consult your doctor immediately or visit the nearby hospital. SYNOPSIS Drug : Temozolomide Pharmacological Category : Antineoplastic agents Therapeutic Indication : Glioblastoma multiforme, Anaplastic astrocytoma Dosage Forms : Capsule, Tablet, Injection MORE INFORMATIONSTORAGE Keep the medicine out of reach of children Store TEMODAL 250MG CAPSULE at room temperature
Frequently Asked Questions
Common questions and answers about Temodal 250mg Capsule 5'S.
What TEMODAL 250MG CAPSULE is used for?
TEMODAL 250MG CAPSULE is used for specific forms of brain tumours in adults with newly diagnosed glioblastoma multiforme, which is used first together with radiotherapy as a concomitant phase of therapy and then used alone as a monotherapy. It is also used in children (above 3 years) and adults to manage malignant glioma, such as glioblastoma multiforme or anaplastic astrocytoma, if they return or get worse after standard management.
How should TEMODAL 250MG CAPSULE be taken?
Take TEMODAL 250MG CAPSULE as advised by your physician. Swallow TEMODAL 250MG CAPSULE with a glass of water and do not chew or crush the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight, and disease condition.
What are the side effects of TEMODAL 250MG CAPSULE?
The most common symptoms of taking TEMODAL 250MG CAPSULE are loss of appetite, difficulty while speaking, headache, vomiting, nausea, diarrhea, and constipation. Consult and inform your doctor if any of these symptoms get worse.
What happens if you forget to take TEMODAL 250MG CAPSULE?
If you forget to take TEMODAL 250MG CAPSULE at the usual time, take your dose as soon as possible and then continue with your medication at the usual times. Avoid taking a double dose to make up for forgotten individual doses. Consult and inform your doctor before taking TEMODAL 250MG CAPSULE if you have queries on the missed dose.
Is TEMODAL 250MG CAPSULE safe to use in children?
TEMODAL 250MG CAPSULE is not recommended for use in children below 3 years of age. There is limited information in patients over 3 years of age who have taken TEMODAL 250MG CAPSULE. Consult your doctor before taking TEMODAL 250MG CAPSULE.
How does TEMODAL 250MG CAPSULE work?
TEMODAL 250MG CAPSULE works by damaging the genetic material (DNA and RNA) of the cancer cells inside the brain cells and works against cell growth and multiplication.
Is TEMODAL 250MG CAPSULE safe during pregnancy?
TEMODAL 250MG CAPSULE should be used in pregnant women only if it is clearly necessary. Women with childbearing potential should use effective contraceptive precautions, which should be continued for at least 6 months following the completion of> management. Consult your doctor before taking TEMODAL 250MG CAPSULE.
Who should not take TEMODAL 250MG CAPSULE?
TEMODAL 250MG CAPSULE is not recommended for use if you have certain kinds of blood cells that are severely reduced, such as white blood cells and platelet count, or if you are allergic to temozolomide or any of the other ingredients of this medicine.
What precautions must be taken while using TEMODAL 250MG CAPSULE?
TEMODAL 250MG CAPSULE should be used with caution in patients with kidney problems such as severe renal impairment, mild, moderate, and severe hepatic impairment, lung disease such as pneumocystis jirovecii pneumonia (serious fungal infection of lungs), signs of anemia (low red blood cell count), signs of low platelet count, or have a risk of other changes in blood cells such as leukemia (blood cancer). Consult your doctor for advice before taking TEMODAL 250MG CAPSULE.
When should I stop taking TEMODAL 250MG CAPSULE?
Stop taking TEMODAL 250MG CAPSULE and contact your doctor if you experience any of the following side effects, such as signs of a severe allergic reaction such as itchy red skin, wheezing or other breathing difficulty, uncontrolled bleeding, seizures (fits), fever, and symptoms of infections such as cough, chills, sweat, chills, and severe headache.
Article Information
Written By
DETAILS Written By Dr. N. Sai Swaroop
Medical Content Writer
Reviewed By
Dr. Sankara Babu Gorle
Medical Expert
Last Updated
17 Jul 2024