Tagrisso 80mg Tablet 10'S

Cancer Oncology (448)Rx required

Key Information

Generic Name

Generic Name Osimertinib 80 mg

Manufacturer

Astrazeneca Pharma India Ltd

Variant

10 Tablet(s) in a Strip

Country of Origin

Sweden

Detailed Information

Introduction

TAGRISSO 80MG TABLET is used in the management of non-small cell lung cancer (NSCLC) in adults who have epidermal growth factor receptor (EGFR) gene mutation. It contains Osimertinib which is an anticancer agent which works by blocking the actions of EGFR genes which is required by the cancer for growth and multiplication. By blocking its actions, Osimertinib stops NSCLC cancer progression which is specific to EGFR mutation. TAGRISSO 80MG TABLET should be used under medical supervision. It can be taken with or without food. Do not stop taking TAGRISSO 80MG TABLET without consulting your doctor. Before taking TAGRISSO 80MG TABLET, inform your doctor if you previously had or currently have any lung problems, heart problems or eye problems, or if you are pregnant or breastfeeding as a precaution. Men and women of childbearing potential must use a suitable contraceptive agent while taking Osimertinib and until 2 months (for women) and 4 months (for men) to avoid pregnancy. If you accidentally became pregnant while taking TAGRISSO 80MG TABLET, inform your doctor immediately. The most common

Uses

OF TAGRISSO 80MG TABLET Management of non-small cell lung cancer (NSCLC) in adults who have EGFR gene mutation

How It Works

TAGRISSO 80MG TABLET contains Osimertinib which is a kinase inhibitor that works by specifically targeting and blocking a protein called EGFR-gene that has mutated in some cancer cells. This mutated EGFR drives the growth of cancer cells. By blocking this protein, osimertinib slows down or stops the growth of the cancer cells, helping to control the disease.

Directions for Use

Take TAGRISSO 80MG TABLET as advised by your physician. It can be taken with or without food. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration of therapy based on your age, body weight and health condition. Do not stop taking TAGRISSO 80MG TABLET without consulting your doctor.

Side Effects

taking TAGRISSO 80MG TABLET are diarrhoea, skin rashes, itching, pain, dryness and redness around fingernails, especially in areas exposed to skin, mouth ulcers, loss of appetite, low WBC and platelet count in the blood, hair thinning, Hand-foot syndrome (causing skin redness, swelling, tingling or burning sensation with cracking of the skin on the palms of hands and/or soles of feet). Consult your doctor if any of these side effects trouble you. USES OF TAGRISSO 80MG TABLET Management of non-small cell lung cancer (NSCLC) in adults who have EGFR gene mutation HOW TAGRISSO 80MG TABLET WORKSTAGRISSO 80MG TABLET contains Osimertinib which is a kinase inhibitor that works by specifically targeting and blocking a protein called EGFR-gene that has mutated in some cancer cells. This mutated EGFR drives the growth of cancer cells. By blocking this protein, osimertinib slows down or stops the growth of the cancer cells, helping to control the disease. DIRECTIONS FOR USETake TAGRISSO 80MG TABLET as advised by your physician. It can be taken with or without food. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration of therapy based on your age, body weight and health condition. Do not stop taking TAGRISSO 80MG TABLET without consulting your doctor. SIDE EFFECTS OF TAGRISSO 80MG TABLETCOMMON Diarrhoea Skin itching, pain, dryness and redness around fingernails, especially in areas exposed to skin Mouth ulcers, sores in the oral cavity Loss of appetite Low WBC and platelet count in the blood Increased creatinine in blood Mild nasal bleeding Hair thinning Hand-foot syndrome (causing skin redness, swelling, tingling or burning sensation with cracking of the skin on the palms of hands and/or soles of feet) Increased blood creatine phosphokinase UNCOMMON Hyperpigmentation on the skin Inflammation of the blood vessels in the skin causing bruising or patches of non-blanching rash on the skin RARE Inflammation of the muscles Stop taking TAGRISSO 80MG TABLET and consult your doctor immediately if you experience any of the following side effects such as: Sudden difficulty in breathing along with fever and cough (lung inflammation) Severe peeling of your skin Persistent fever, bruising or bleeding, increasing tiredness, pale skin and infection Skin rashes, itching, raised round red patches on the skin Target skin lesions with itching and rashes Eye problems (watery eyes, light sensitivity, eye pain, redness and vision changes) Severe skin reactions (such as reddish target-like macules or circular patches often with central blisters on the trunk, skin peeling, ulcers of mouth, throat, nose, genitals and eyes and be preceded by fever and flu-like symptoms) Abnormal heartbeat, breathing difficulties and heart problems Aplastic anaemia (a blood disorder caused due to bone marrow suppression characterised by persistent fever, bruising or bleeding more easily, increased tiredness and a decrease in your ability to fight infection)

Warnings & Precautions

& PRECAUTIONSPREGNANCYConsult your doctorBefore taking TAGRISSO 80MG TABLET, inform your doctor if you are pregnant or think you may be pregnant as a precaution. Women of childbearing potential must use a suitable contraceptive agent while taking TAGRISSO 80MG TABLET to avoid pregnancy and until 2 months after taking the last dose of osimertinib. If you accidentally became pregnant while taking TAGRISSO 80MG TABLET, consult your doctor for advice. BREASTFEEDINGContraindicatedTAGRISSO 80MG TABLET is not recommended for use in breastfeeding women due to lack of safety data. Therefore, consult your doctor for advice. DRIVING AND USING MACHINESUse with CautionDo not drive or handle any heavy tools or machines if your ability is affected by TAGRISSO 80MG TABLET. ALLERGYContraindicatedDo not take TAGRISSO 80MG TABLET if you are allergic to Osimertinib. LUNGSUse with CautionTAGRISSO 80MG TABLET should be used with caution in patients who suffered from lung inflammation (interstitial lung disease). Therefore, consult your doctor before taking it. HEART DISEASEUse with CautionTAGRISSO 80MG TABLET should be used with caution in patients who have ever had heart problems. Therefore, consult your doctor before taking it. USE IN PEDIATRICSConsult your doctorThere is no proper information regarding the use of TAGRISSO 80MG TABLET in children and adolescents (aged 18 years or below). Therefore, TAGRISSO 80MG TABLET is not recommended for use in children unless considered necessary by the physician. USE IN GERIATRICSUse with CautionTAGRISSO 80MG TABLET should be used with caution in elderly patients. Therefore, consult your doctor for advice. OTHERSBefore taking TAGRISSO 80MG TABLET, inform your doctor if you: Have a history of eye problems

Drug Interactions

SA. Drug-Drug interactions: St. John’s Wort (Hypericum perforatum used for depression) Antiepileptics (such as phenytoin, carbamazepine or phenobarbital) Anti-TB agents (such as rifabutin or rifampicin) Rosuvastatin (an anti-hyperlipidemic agent) Oral hormonal contraceptive pill Antihypertensive agents (such as aliskiren, bosentan) Anti-HIV agents (such as Efavirenz and etravirine) Modafinil (used for sleep disorders) Dabigatran (used to prevent blood clots) Digoxin (used for irregular heart beat) Overdosage: If you or anyone else accidentally taken too many doses of TAGRISSO 80MG TABLET, consult your doctor for advice or visit the hospital straight away. SYNOPSIS Drug : Osimertinib Pharmacological Category : Kinase inhibitors Therapeutic Indication : Non-small cell lung cancer (NSCLC) Dosage Forms : Tablet MORE INFORMATIONSTORAGE Keep TAGRISSO 80MG TABLET out of reach of children Store TAGRISSO 80MG TABLET at room temperature

Frequently Asked Questions

Common questions and answers about Tagrisso 80mg Tablet 10'S.

Q

What is TAGRISSO 80MG TABLET used for?

A

TAGRISSO 80MG TABLET is used in the management of non-small cell lung cancer (NSCLC) in adults who have epidermal growth factor receptor (EGFR) gene mutation.

Q

How to take TAGRISSO 80MG TABLET?

A

Take TAGRISSO 80MG TABLET as advised by your physician. It can be taken with or without food. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Do not stop taking TAGRISSO 80MG TABLET without consulting your doctor.

Q

How TAGRISSO 80MG TABLET works?

A

TAGRISSO 80MG TABLET contains Osimertinib which is a kinase inhibitor that works by specifically targeting and blocking a protein called EGFR-gene that has mutated in some cancer cells. This mutated EGFR drives the growth of cancer cells. By blocking this protein, osimertinib slows down or stops the growth of the cancer cells, helping to control the disease.

Q

What are the common side effects of taking TAGRISSO 80MG TABLET?

A

The most common side effects of taking TAGRISSO 80MG TABLET are diarrhoea, skin rashes, itching, pain, dryness and redness around fingernails, especially in areas exposed to skin, mouth ulcers, loss of appetite, low WBC and platelet count in the blood, hair thinning, Hand-foot syndrome (causing skin redness, swelling, tingling or burning sensation with cracking of the skin on the palms of hands and/or soles of feet). Consult your doctor if any of these side effects trouble you.

Q

Can TAGRISSO 80MG TABLET be used during pregnancy?

A

Before taking TAGRISSO 80MG TABLET, inform your doctor if you are pregnant or think you may be pregnant as a precaution. Women of childbearing potential must use a suitable contraceptive agent while taking TAGRISSO 80MG TABLET to avoid pregnancy and until 2 months after taking the last dose of osimertinib. If you accidentally became pregnant while taking TAGRISSO 80MG TABLET, consult your doctor for advice.

Q

What precautions must be followed while taking TAGRISSO 80MG TABLET?

A

TAGRISSO 80MG TABLET should be used under medical supervision. It can be taken with or without food. Do not stop taking TAGRISSO 80MG TABLET without consulting your doctor. Before taking TAGRISSO 80MG TABLET, inform your doctor if you previously had or currently have any lung problems, heart problems or eye problems, or if you are pregnant or breastfeeding as a precaution.Men and women of childbearing potential must use a suitable contraceptive agent while taking Osimertinib and until 2 months (for women) and 4 months (for men) to avoid pregnancy. If you accidentally became pregnant while taking TAGRISSO 80MG TABLET, inform your doctor immediately.

Q

Will Olaparib cure cancer?

A

TAGRISSO 80MG TABLET will help you effectively manage cancer. It has been proven to improve overall survival and quality of life in cancer patients. Complete cure of cancer depends on the severity of the disease and how your body responds to the therapy.

Article Information

DW

Written By

DETAILS Written By Srilekha. R

Medical Content Writer

DS

Reviewed By

Dr. Sankara Babu Gorle

Medical Expert

Last Updated

27 Aug 2024

Tags

#cancer oncology (448)#generic name osimertinib 80 mg