Tafmune EM Tablet 30'S
Key Information
Generic Name
Generic Name Emtricitabine 200 mg+Tenofovir Alafenamide 25 mg
Manufacturer
Cipla Ltd
Variant
30 Tablet(s) in a Container
Country of Origin
India
Detailed Information
Introduction
TAFMUNE EM TABLET is a combination of Tenofovir alafenamide and Emtricitabine which belongs to the group of medicines called Antiretroviral drugs. It is used in adults and adolescents (aged 12 years and older) along with other medicines to manage human immunodeficiency virus 1 (HIV-1) infection. It can also be used to reduce the risk of getting HIV infection in adult and adolescent men who have intercourse with men. HIV targets the immune system and weakens your defence against many infections that people with healthy immune systems can fight off. As the virus destroys and impairs the function of immune cells, infected individuals gradually become immunodeficient and reach the most advanced stage of HIV infection called Acquired Immunodeficiency Syndrome (AIDS). It may present with the symptoms of any other infection like fever, throat pain, extreme tiredness, weight loss, muscle pain, etc. During course of the management your doctor might take regular blood tests to avoid any untoward
Uses
OF TAFMUNE EM TABLET Manage human immunodeficiency virus 1 (HIV-1) infection (in adults and adolescents (aged 12 years and older) along with other medicines) Reduces the risk of getting HIV infection (in adult and adolescent men who have intercourse with men)
How It Works
TAFMUNE EM TABLET helps to control HIV infection, where tenofovir alafenamide gets subsequently phosphorylated to the pharmacologically active metabolite tenofovir diphosphate and emtricitabine gets phosphorylated by cellular enzymes to emtricitabine triphosphate. These metabolites inhibit HIV replication through incorporation into viral DNA by the HIV reverse transcriptase, which results in DNA chain-termination.
Directions for Use
Take TAFMUNE EM TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
Side Effects
alcohol while taking TAFMUNE EM TABLET as it may cause bone problems. TAFMUNE EM TABLET is not suitable for use in children and adolescents (aged less than 11 years). Before taking TAFMUNE EM TABLET, inform your doctor if you have any flu-like illness, kidney, heart or liver problems, hepatitis B or other sexually transmitted infections. TAFMUNE EM TABLET should be used with caution in pregnant women only if advised by the doctor. Breastfeeding is not recommended while taking TAFMUNE EM TABLET as it can pass into breast milk. The most common side effects of taking TAFMUNE EM TABLET are nausea, headache, dizziness, diarrhoea, stomach pain and tiredness. Consult your doctor if any of the above side effects worsen. USES OF TAFMUNE EM TABLET Manage human immunodeficiency virus 1 (HIV-1) infection (in adults and adolescents (aged 12 years and older) along with other medicines) Reduces the risk of getting HIV infection (in adult and adolescent men who have intercourse with men) HOW TAFMUNE EM TABLET WORKSTAFMUNE EM TABLET helps to control HIV infection, where tenofovir alafenamide gets subsequently phosphorylated to the pharmacologically active metabolite tenofovir diphosphate and emtricitabine gets phosphorylated by cellular enzymes to emtricitabine triphosphate. These metabolites inhibit HIV replication through incorporation into viral DNA by the HIV reverse transcriptase, which results in DNA chain-termination. DIRECTIONS FOR USETake TAFMUNE EM TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition. SIDE EFFECTS OF TAFMUNE EM TABLETCOMMON nausea, vomiting abnormal dreams headache, dizziness diarrhoea stomach pain flatulence rash extreme tiredness UNCOMMON problems with digestion resulting in discomfort after eating swelling of the face, tongue, lips or throat itching hives joint pain RAREStop taking TAFMUNE EM TABLET and consult your doctor immediately if you experience any of the following side effects: signs of inflammation or infection autoimmune disorders (signs include muscle weakness, weakness beginning in the hands and feet and moving up towards the trunk of the body, throbbing heartbeat, shaking or hyperactivity) worsening of hepatitis B virus infection changes in your immune system new or worsening of existing kidney problems, including kidney failure too much lactic acid in your blood (weakness or tiredness, unusual muscle pain, breathlessness, stomach pain with nausea and vomiting, cold or blue hands and feet, dizziness or light-headedness, fast or abnormal heartbeat) severe liver problems (yellowing of skin or the white part of your eyes, dark urine, light-coloured stools, loss of appetite, nausea or abdominal pain)
Warnings & Precautions
& PRECAUTIONSPREGNANCYTAFMUNE EM TABLET should be used with caution in pregnant women only if considered clearly necessary as it is not known if it can cause any potential harm to the unborn baby. Inform your doctor if you get pregnant during management with TAFMUNE EM TABLET. BREASTFEEDINGBreastfeeding is not recommended while taking TAFMUNE EM TABLET as it can pass into breast milk. Consult your doctor before taking it. DRIVING AND USING MACHINESDo not drive or use any machines if you feel dizzy after taking TAFMUNE EM TABLET. ALCOHOLAvoid consumption of alcohol while taking TAFMUNE EM TABLET as it may cause bone problems. KIDNEYTAFMUNE EM TABLET should be used with caution in patients with kidney disease. Consult your doctor before taking TAFMUNE EM TABLET. LIVERTAFMUNE EM TABLET should be used with caution in patients with liver problems including hepatitis B or C infection. Consult your doctor before taking TAFMUNE EM TABLET. ALLERGYDo not take TAFMUNE EM TABLET if you are allergic to Tenofovir alafenamide or Emtricitabine. OTHERSBefore taking TAFMUNE EM TABLET, inform your doctor if you: have a flu-like illness were earlier infected with HIV Use in Pediatrics: TAFMUNE EM TABLET is not recommended for use in children (aged less than 11 years) or weighing less than 35 kg, as it is not studied in this population yet. Consult your child’s doctor for advice. Use in Geriatrics: TAFMUNE EM TABLET should be used with caution in elderly patients. Consult your doctor before taking TAFMUNE EM TABLET.
Drug Interactions
SA. Drug - Drug interactions: Before taking TAFMUNE EM TABLET, inform your doctor if you are taking any of the following medicines: medicines used to manage hepatitis B infection (Ex. tenofovir disoproxil, lamivudine, adefovir dipivoxil) medicines used to manage bacterial infections like tuberculosis (Ex. rifabutin, rifampicin, rifapentine) medicines used to manage HIV infection (Ex. tipranavir) medicines used to manage fits (Ex. carbamazepine, oxcarbazepine, phenobarbital, phenytoin) St. John’s wort (herbal remedy used to manage depression and anxiety) Overdosage: If you or anyone else accidentally takes too much of TAFMUNE EM TABLET, consult your doctor immediately or visit the nearby hospital. SYNOPSIS Drug : Tenofovir alafenamide and Emtricitabine Pharmacological Category : Nucleotide Reverse Transcriptase Inhibitor (NtRTI),Nucleoside Reverse Transcriptase Inhibitor (NRTI) Therapeutic Indication : HIV infection Dosage Forms : Tablet MORE INFORMATION Keep TAFMUNE EM TABLET out of reach of children Store at room temperature
Frequently Asked Questions
Common questions and answers about Tafmune EM Tablet 30'S.
Does TAFMUNE EM TABLET cure HIV infection?
TAFMUNE EM TABLET does not completely manage HIV infection. While taking this medicine, you may still develop infections or other diseases associated with HIV infection. Consult your doctor immediately for advice if you develop infections or diseases.
Can TAFMUNE EM TABLET be used to manage HIV infection?
TAFMUNE EM TABLET can be used to reduce the risk of getting HIV infection in adult and adolescent men (who weigh at least 35 kg) who have intercourse with men. It can only be used for this purpose if you are HIV-negative. Consult your doctor before taking TAFMUNE EM TABLET.
What precautions should I follow while taking TAFMUNE EM TABLET to reduce the risk of HIV infection?
While taking TAFMUNE EM TABLET to reduce the risk of HIV infection, get tested for HIV regularly. Take the medicine every day to reduce your risk, not just when you think you are at risk of getting infected. Practice safer sex by using condoms to reduce the risk of getting other sexually transmitted diseases.
Can I stop taking TAFMUNE EM TABLET on my own?
Do not stop taking TAFMUNE EM TABLET without asking your doctor. If you are taking TAFMUNE EM TABLET to manage HIV infection, stopping it can seriously impact the effect of future management. If it is stopped for any reason, ask your doctor before you restart taking this medicine. If you are taking TAFMUNE EM TABLET to reduce the risk of getting infected, do not stop taking it or miss any doses as it may increase your risk of getting HIV infection.
Can I take TAFMUNE EM TABLET if I’m on dialysis?
Take TAFMUNE EM TABLET as directed by your doctor. If you are undergoing dialysis regularly, take your daily dose of this medicine after completion of dialysis. Consult your doctor for advice before taking TAFMUNE EM TABLET.
What if I miss a dose of TAFMUNE EM TABLET?
It is important not to miss a dose of TAFMUNE EM TABLET but if you do, take the next dose as soon as possible if you remember within 18 hours of previous dose. Do not take the forgotten dose if you remember after 18 hours or more of previous dose. Wait and take your next dose as per schedule.
Article Information
Written By
DETAILS Written By Dr. R. Dinesh John Rajkumar
Medical Content Writer
Reviewed By
Dr. Sankara Babu Gorle
Medical Expert
Last Updated
19 Jan 2023