SULFAZEE 500 Tablet 15's
Key Information
Generic Name
Generic Name Sulphasalazine 500 mg Also Known As: Sulfasalazine
Manufacturer
PREVEGO HEALTHCARE & RESEARCH PRIVATE LIMITED (Generics)
Variant
15 Tablet(s) in a Strip
Country of Origin
India
Detailed Information
Introduction
SULFAZEE 500 TABLET contains Sulfasalazine which belongs to the group of medicines called Aminosalicylates. It is used to manage inflammatory bowel disease such as Ulcerative Colitis, Crohn’s disease and rheumatoid arthritis. Ulcerative Colitis is an inflammatory disease which affects only the large bowel (colon and back passage), the lining of the bowel becomes inflamed (red and swollen) and symptoms include abdominal pain and diarrhea (may have blood and mucus). Crohn’s disease is an inflammatory disease which affect any part of the digestive system from the mouth to the anus, most commonly affects the last part of the small bowel and the first part of the large bowel, symptoms include abdominal pain and diarrhea (may be bloody). It can also be used to manage rheumatoid arthritis (swelling, pain, stiffness of joints) Your doctor might want you to take certain blood, kidney and liver function tests during the management. Drink enough fluids during this management to avoid problems with kidney. Before taking SULFAZEE 500 TABLET inform your doctor if you have porphyria (a rare blood pigment disorder), jaundice, kidney, liver, blood problems, glucose-6-phosphate dehydrogenase deficiency, history of recurring chronic infection, asthma, arthritis. Inform your doctor if you are pregnant or breastfeeding. SULFAZEE 500 TABLET is not recommended for use in children below 2 years of age. The most common
Uses
OF SULFAZEE 500 TABLETIt is used to manage: ulcerative colitis crohn’s disease rheumatoid arthritis
How It Works
SULFAZEE 500 TABLET works by suppressing the overactivity of the immune system in autoimmune diseases and blocks the chemical messengers that cause inflammation (swelling).
Directions for Use
Take SULFAZEE 500 TABLET as advised by your physician. Swallow the medicine with water. Do not crush or chew the medicine. Your doctor will decide the right dose and duration depending upon your age, body weight and disease condition.
Side Effects
taking SULFAZEE 500 TABLET are indigestion, heartburn, nausea, dizziness and headache. Consult your doctor if side effects gets worse. USES OF SULFAZEE 500 TABLETIt is used to manage: ulcerative colitis crohn’s disease rheumatoid arthritis HOW SULFAZEE 500 TABLET WORKSSULFAZEE 500 TABLET works by suppressing the overactivity of the immune system in autoimmune diseases and blocks the chemical messengers that cause inflammation (swelling). DIRECTIONS FOR USETake SULFAZEE 500 TABLET as advised by your physician. Swallow the medicine with water. Do not crush or chew the medicine. Your doctor will decide the right dose and duration depending upon your age, body weight and disease condition. SIDE EFFECTS OF SULFAZEE 500 TABLETCOMMON indigestion heartburn nausea dizziness headache changes in taste ringing in the ears cough itching of the skin purple discolorations on the skin joint pain protein in urine fever UNCOMMON depression shortness of breath abdominal pain diarrhea vomiting hair loss hives puffiness around the eyes and face RAREStop taking SULFAZEE 500 TABLET and contact your doctor immediately if you experience any of the following side effects: allergic reaction such as sudden wheeziness, difficulty in breathing, swelling of eyelids, face or lips, rash or itching (affecting the whole body) jaundice severe skin rash that causes blistering (affects the mouth and tongue), life-threatening skin rashes (exfoliate dermatitis, Stevens-Johnson syndrome, toxic epidermal necrolysis) fever, pains in your joints, hives, swollen glands, rash and itching (signs of serum sickness) any unexplained bleeding bruising, fever, rash, pallor (paleness), severe sore throat or tiredness (signs of abnormality in blood) rash or fever or swollen gland may be a sign of DRESS (drug rash with eosinophilia and systemic symptoms)
Warnings & Precautions
& PRECAUTIONSPREGNANCYInform your doctor if you are pregnant or planning to have a baby before taking SULFAZEE 500 TABLET. Your doctor will decide whether to take it or not. BREASTFEEDINGAvoid breastfeeding while taking SULFAZEE 500 TABLET as there have been reports of diarrhea or blood in the stools of babies. Consult your doctor before taking it. DRIVING AND USING MACHINESSULFAZEE 500 TABLET is unlikely to affect your ability to drive or use machines. KIDNEYSULFAZEE 500 TABLET should be used with caution in patients with kidney disease. Consult your doctor before taking. LIVERSULFAZEE 500 TABLET should be used with caution in patients with liver disease. Consult your doctor before taking. ALLERGYDo not take SULFAZEE 500 TABLET if you are allergic to Sulfasalazine, salicylates (Ex. aspirin) or sulfonamides (type of antibiotic) or any other ingredients of this medicine. LUNGSSULFAZEE 500 TABLET should be used with caution in patients with asthma. Consult your doctor before taking. OTHERSSULFAZEE 500 TABLET is not recommended for use if you: have porphyria (a rare blood pigment disorder) have jaundice Before taking SULFAZEE 500 TABLET, inform your doctor if you: have blood disorders have glucose-6-phosphate dehydrogenase deficiency (an inherited condition) have a history of recurring chronic infections your child has arthritis Use in pediatrics: SULFAZEE 500 TABLET is not recommended for use in children below 2 years of age. Consult your doctor before taking. Use in geriatrics: SULFAZEE 500 TABLET should be used with caution in elderly patients. Consult your doctor before taking.
Drug Interactions
SA. Drug-Drug interactions: Before taking SULFAZEE 500 TABLET, inform your doctor if you are taking any of the following medicine: medicine for high blood sugar (Ex. metformin, glipizide) digoxin (to manage heart failure) folic acid or folate (Ex. Spina Bifida) to reduce risk of neural tube defect azathioprine and mercaptopurine (help to suppress your body’s immune response in organ transplantation and certain chronic inflammations (Ex. rheumatoid arthritis)) methotrexate (used to manage rheumatoid arthritis) methenamine (for managing urinary tract infections) Overdosage: If you or anyone else accidentally takes too much of SULFAZEE 500 TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose are nausea and vomiting. SYNOPSIS Drug : Sulfasalazine Pharmacological Category : Anti-inflammatory Therapeutic Indication : Ulcerative colitis, Crohn’s disease, Rheumatoid arthritis Dosage Forms : Tablet MORE INFORMATION Keep SULFAZEE 500 TABLET out of reach of children Store below 25°C
Article Information
Written By
ity (HPRA). [Revised in September 2018] [Accessed on 13th July 2022] https://www.hpra.ie/img/uploaded/swedocuments/d3fcb110-b8d2-45fc-bfd2-d9d4dfeeca41.pdf 6. Sulfasalazine. Drugs.com. [Revised in June 2022] [Accessed on 13th July 2022] https://www.drugs.com/cons/sulfasalazine.html USEFUL DIAGNOSTIC TESTS Blood and urine test Kidney function test Liver test AUTHOR DETAILS Written By Dr. Janet.C
Medical Content Writer
Reviewed By
Dr. Sankara Babu Gorle
Medical Expert
Last Updated
03 Dec 2022