Smodace 50mg Tablet 10'S
Key Information
Generic Name
Generic Name Diacerein 50 mg
Manufacturer
East West Pharma
Variant
10 Tablet(s) in a Strip
Country of Origin
NA
Detailed Information
Introduction
SMODACE 50MG TABLET contains Diacerein which belongs to the group of medicines called Anthraquinones. It is used for the symptomatic management of functional symptoms of osteoarthritis. Osteoarthritis is a common progressive disorder affecting primarily weight bearing joints (knee, hip), characterised by progressive destruction of cartilage causing pain, limitation of motion, stiffness, deformity and disability. Prior to the management, your doctor may want you to take several blood tests to understand your existing condition like liver disease. Avoid taking alcohol with SMODACE 50MG TABLET as it may increase the risk of liver damage. SMODACE 50MG TABLET is not recommended for use in patients having liver or kidney disease, colitis or crohn’s disease, partial or complete intestinal obstruction or abdominal pain with an unknown cause. Inform your doctor, if you have kidney or urinary problems, history of diarrhea, irritable bowel disease, rare hereditary diseases such as congenital galactosemia, glucose or galactose malabsorption syndrome or lactase deficiency. SMODACE 50MG TABLET is not recommended for use in pregnant and breastfeeding women. Contact your doctor before taking. SMODACE 50MG TABLET is not recommended for use in children and adolescents under 15 years of age. Contact your doctor before taking. SMODACE 50MG TABLET should be used with caution in elderly aged above 65 years. Contact your doctor before taking. The most common
Uses
OF SMODACE 50MG TABLET Used for the symptomatic management of Osteoarthritis
How It Works
SMODACE 50MG TABLET works by blocking the chemicals (interleukin-1) causing inflammation and destruction of cartilage in the body. It also stimulates the production of certain chemicals called transforming growth factor-β (TGF-β) which triggers chondrocyte proliferation and stimulates the production of collagen and proteoglycan, glycosaminoglycans and hyaluronic acid. Therefore SMODACE 50MG TABLET manages the cartilage destruction and improves symptoms in patients with osteoarthritis.
Directions for Use
Take SMODACE 50MG TABLET as advised by your physician. Swallow the medicines with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
Side Effects
taking SMODACE 50MG TABLET are diarrhea, soft stools, pain in abdomen, frequent bowel movements, flatulence, skin rash, itching, and eczema. Contact your doctor if any of the side effects worsen. USES OF SMODACE 50MG TABLET Used for the symptomatic management of Osteoarthritis HOW SMODACE 50MG TABLET WORKSSMODACE 50MG TABLET works by blocking the chemicals (interleukin-1) causing inflammation and destruction of cartilage in the body. It also stimulates the production of certain chemicals called transforming growth factor-β (TGF-β) which triggers chondrocyte proliferation and stimulates the production of collagen and proteoglycan, glycosaminoglycans and hyaluronic acid. Therefore SMODACE 50MG TABLET manages the cartilage destruction and improves symptoms in patients with osteoarthritis. DIRECTIONS FOR USETake SMODACE 50MG TABLET as advised by your physician. Swallow the medicines with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition. SIDE EFFECTS OF SMODACE 50MG TABLETCOMMON diarrhea soft stools pain in abdomen frequent bowel movements flatulence skin rash, itching, eczema UNCOMMON increased liver enzymes RARE pigmentation of colorectal mucosa (melanosis coli) Stop taking SMODACE 50MG TABLET and contact your doctor immediately if you experience any of the following side effects: diarrhea (risk of dehydration and hypokalemia) signs of liver disease such as increased liver enzyme, tiredness, and loss of appetite, jaundice (yellowish discoloration of skin and white of eyes), abdominal pain, nausea, vomiting, change in stool and urine colour, reduced consciousness, itchy skin
Warnings & Precautions
& PRECAUTIONSPREGNANCYSMODACE 50MG TABLET is generally not recommended for use in pregnant women. Consult your doctor before taking. BREASTFEEDINGSMODACE 50MG TABLET is generally not recommended for use in breastfeeding women as it is not known if this medicine passes into breast milk. Consult your doctor before taking. ALCOHOLAvoid consumption of alcohol while taking SMODACE 50MG TABLET as it increases the risk of liver damage. KIDNEYSMODACE 50MG TABLET is not recommended for use in patients with severe kidney disease. Consult your doctor before taking. LIVERSMODACE 50MG TABLET is not recommended for use in patients with liver disease. Consult your doctor before taking. ALLERGYDo not take SMODACE 50MG TABLET if you are allergic to Diacerein or any of the other ingredients of this medicine. OTHERSSMODACE 50MG TABLET is not recommended for use if you have: colitis or crohn’s disease partial or complete intestinal obstruction abdominal pain with an unknown cause rapidly progressive (worsening) hip osteoarthritis Before taking SMODACE 50MG TABLET, inform your doctor if you have: urinary system problems irritable bowel disease rare hereditary diseases such as congenital galactosemia, glucose or galactose malabsorption syndrome or lactase deficiency Use in pediatrics: SMODACE 50MG TABLET is generally not recommended for use in children and adolescents under 15 years of age. Consult your doctor before taking. Use in geriatrics: SMODACE 50MG TABLET is not recommended for use in elderly patients aged above 65 years. Consult your doctor before taking.
Drug Interactions
SA. Drug - Drug interactions: Before taking SMODACE 50MG TABLET, inform your doctor if you are taking any of the following medicine: laxatives (medicines used to manage constipation) antacids (Ex. Aluminium hydroxide, magnesium hydroxide or calcium hydroxide) (medicines used to manage acidity) diuretics (medicines used for hypertension) digoxin, digitoxin (medicines used for heart failure) amoxicillin/clavulanic acid (medicines used for infections) chemotherapy (medicines used to manage cancer) Overdosage: If you or anyone else accidentally takes too much of SMODACE 50MG TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose are diarrhea. SYNOPSIS Drug : Diacerein Pharmacological Category : Anthraquinones Therapeutic Indication : Osteoarthritis Dosage Forms : Tablet, Capsule MORE INFORMATION Keep SMODACE 50MG TABLET out of the sight and reach of children Store SMODACE 50MG TABLET below 25°C
Article Information
Written By
DETAILS Written By Dr. Janet.C
Medical Content Writer
Reviewed By
Dr. Sankara Babu Gorle
Medical Expert
Last Updated
30 Nov 2022