SENTIBRIM BZ Ophthalmic Suspension 5ml
Key Information
Generic Name
Generic Name Brimonidine 2 mg+Brinzolamide 10 mg
Manufacturer
Sentiss Pharma Pvt Ltd
Country of Origin
India
Detailed Information
Introduction
INTRODUCTION ABOUT SENTIBRIM BZ OPHTHALMIC SUSPENSIONSENTIBRIM BZ OPHTHALMIC SUSPENSION is a combination of Brimonidine and Brinzolamide which belongs to the group of medicines called Ophthalmic anti-glaucoma agents. It is used in adults to manage ocular hypertension and glaucoma (increased pressure within the eyes). It is typically used in patients who are not responding well to therapy with single agents. SENTIBRIM BZ OPHTHALMIC SUSPENSION is for ophthalmic use only. Instil few drops of this medicine into the affected eye(s). Do not touch the tip of the dropper with your eye or with other body surface to avoid contamination. If you wear soft contact lenses, remove the lens before using SENTIBRIM BZ OPHTHALMIC SUSPENSION and wait for at least 15 minutes before reinsertion. Before using SENTIBRIM BZ OPHTHALMIC SUSPENSION inform your doctor if you have any liver, kidney or heart problems. You must also inform your doctor if you have low or high blood pressure, narrow-angle glaucoma, dry eyes, depression or poor blood circulation in your body as a precaution. Consult your doctor before using SENTIBRIM BZ OPHTHALMIC SUSPENSION if you are pregnant or breastfeeding. The most common
Uses
OF SENTIBRIM BZ OPHTHALMIC SUSPENSION Manage ocular hypertension and glaucoma in adults
How It Works
SENTIBRIM BZ OPHTHALMIC SUSPENSION works by decreasing the production of excessive eye fluids (aqueous humour) while simultaneously increasing their drainage. As a result, it reduces strain on the eyes which therefore reduces elevated intraocular pressure.
Directions for Use
Use SENTIBRIM BZ OPHTHALMIC SUSPENSION as advised by your doctor. It is for ophthalmic use only. Wash your hands before use. Instil few drops of SENTIBRIM BZ OPHTHALMIC SUSPENSION into the affected eye. Close your eyes and press the corner of your eye with your finger for a minute. Do not touch the tip of the dropper with your eye or with other body surface to avoid contamination. Apply applying SENTIBRIM BZ OPHTHALMIC SUSPENSION, leave a time gap of at least 5 minutes before applying other eye drops or ointment. If you wear soft contact lenses, remove the lens before applying SENTIBRIM BZ OPHTHALMIC SUSPENSION and wait for at least 15 minutes before reinsertion. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition. Do not stop using SENTIBRIM BZ OPHTHALMIC SUSPENSION without consulting your doctor, as the pressure within the eye may raise once again.
Side Effects
using SENTIBRIM BZ OPHTHALMIC SUSPENSION are eye pain, redness, discomfort, irritation, itching or inflammation, blurred vision and bad taste. Consult your doctor if they trouble you. USES OF SENTIBRIM BZ OPHTHALMIC SUSPENSION Manage ocular hypertension and glaucoma in adults HOW SENTIBRIM BZ OPHTHALMIC SUSPENSION WORKSSENTIBRIM BZ OPHTHALMIC SUSPENSION works by decreasing the production of excessive eye fluids (aqueous humour) while simultaneously increasing their drainage. As a result, it reduces strain on the eyes which therefore reduces elevated intraocular pressure. DIRECTIONS FOR USEUse SENTIBRIM BZ OPHTHALMIC SUSPENSION as advised by your doctor. It is for ophthalmic use only. Wash your hands before use. Instil few drops of SENTIBRIM BZ OPHTHALMIC SUSPENSION into the affected eye. Close your eyes and press the corner of your eye with your finger for a minute. Do not touch the tip of the dropper with your eye or with other body surface to avoid contamination. Apply applying SENTIBRIM BZ OPHTHALMIC SUSPENSION, leave a time gap of at least 5 minutes before applying other eye drops or ointment. If you wear soft contact lenses, remove the lens before applying SENTIBRIM BZ OPHTHALMIC SUSPENSION and wait for at least 15 minutes before reinsertion. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition. Do not stop using SENTIBRIM BZ OPHTHALMIC SUSPENSION without consulting your doctor, as the pressure within the eye may raise once again. SIDE EFFECTS OF SENTIBRIM BZ OPHTHALMIC SUSPENSIONCOMMON eye redness, itching or inflammation eye pain or discomfort blurred vision drowsiness, dizziness bad taste in mouth dry mouth UNCOMMON eye swelling, watery eyes eye sensitivity towards sunlight eyes low blood pressure depression feeling weak, nervous or irritated shortness of breath nose bleeds, runny nose, sore throat, cough and cold nasal dryness, sneezing ringing in the ears nausea, vomiting skin rash or itching, hair loss muscle pain or spasm low sex drive, problems in erection RAREStop using SENTIBRIM BZ OPHTHALMIC SUSPENSION and contact your immediately if you experience any of the following side effects: pale skin, sleepiness, low body temperature and breathing difficulties severe allergic reactions (such as skin rash, swelling of the eye, eyelids, face, lips, tongue, hands or throat leading to difficulty in breathing)
Warnings & Precautions
& PRECAUTIONSPREGNANCYSENTIBRIM BZ OPHTHALMIC SUSPENSION is generally not recommended for use in pregnant women unless considered necessary by the physician. Therefore, consult your doctor before using it. Women of childbearing age should use proper contraceptive method to avoid pregnancy while undergoing therapy with SENTIBRIM BZ OPHTHALMIC SUSPENSION. BREASTFEEDINGSENTIBRIM BZ OPHTHALMIC SUSPENSION is generally not recommended for use in breastfeeding women unless considered necessary by the physician. Therefore, consult your doctor before using it. DRIVING AND USING MACHINESDo not drive or operate any heavy tools or machines if you experience blurred vision, drowsiness or tiredness after using SENTIBRIM BZ OPHTHALMIC SUSPENSION. ALCOHOLAvoid the consumption of alcohol while using SENTIBRIM BZ OPHTHALMIC SUSPENSION as it may increase the risk of side effects. KIDNEYSENTIBRIM BZ OPHTHALMIC SUSPENSION is not recommended for use in patients with severe kidney problems. Therefore, consult your doctor before using it. LIVERSENTIBRIM BZ OPHTHALMIC SUSPENSION should be used with caution in patients with liver problems. Therefore, consult your doctor before using it. ALLERGYTalk to your doctor if you are allergic to Brimonidine, Brinzolamide, sulphonamides (such as glipizide, gliclazide) or diuretics (such as furosemide). HEART DISEASESENTIBRIM BZ OPHTHALMIC SUSPENSION should be used with caution in patients with heart diseases (such as coronary heart disease or heart failure). Therefore, consult your doctor before using it. OTHERSSENTIBRIM BZ OPHTHALMIC SUSPENSION is not recommended for use if you: have hyperchloremic acidosis (a condition where there is too much of acidity in blood) Before using SENTIBRIM BZ OPHTHALMIC SUSPENSION, inform your doctor if you: have dry eyes or problems in your cornea have narrow angle glaucoma (a type of rapid increase in pressure within the eye) have high or low blood pressure have depression have poor blood circulation in the body (such as Raynaud’s disease) have reduced blood supply to the brain or reduced mental capacity wear soft contact lenses Use in pediatrics: SENTIBRIM BZ OPHTHALMIC SUSPENSION is generally not recommended for use in children and adolescents (aged below 18 years). Therefore, consult your doctor before using it. Use in geriatrics: SENTIBRIM BZ OPHTHALMIC SUSPENSION should be used with caution in elderly patients. Therefore, consult your doctor before using it.
Drug Interactions
SA. Drug-Drug interactions: Before using SENTIBRIM BZ OPHTHALMIC SUSPENSION, inform your doctor if you are taking any of the following medicines such as: medicines used to manage depression such as (Ex. citalopram, escitalopram, fluoxetine, sertraline, amitriptyline, nortriptyline, moclobemide, selegiline, phenelzine, isocarboxazid, clomipramine, mianserin, venlafaxine and duloxetine) medicines used to induce sleep (Ex. alprazolam, midazolam, phenobarbital) medicines used to manage mental illness (Ex. chlorpromazine, methylphenidate, reserpine) medicines used to lower blood pressure (Ex. enalapril, ramipril) digoxin (a medicine used to manage irregular heartbeat) anaesthetics (used to induce numbness) Ex. lidocaine other carbonic anhydrase inhibitors (used to manage glaucoma) Ex. acetazolamide and dorzolamide medicines used to manage viral infections (such as ritonavir, nelfinavir, atazanavir) medicines used to manage fungal infections (such as ketoconazole, fluconazole, itraconazole) medicines used to manage bacterial infections (such as amoxicillin, cefixime, azithromycin, clarithromycin) Overdosage: If you or anyone else accidentally used more SENTIBRIM BZ OPHTHALMIC SUSPENSION, rinse your eye with warm water. If still irritation persists, consult your doctor. If you or anyone else accidentally swallowed this medicine, contact your doctor immediately. Symptoms of overdose might include slow heartbeat, low or high blood pressure, difficulty in breathing and confusion or nerve problems. SYNOPSIS Drug : Brimonidine, Brinzolamide Pharmacological Category : Alpha adrenergic receptor agonists, Carbonic anhydrase inhibitors Therapeutic Indication : Glaucoma, Ocular hypertension Dosage Forms : Eye drops, Ophthalmic suspension MORE INFORMATION Keep SENTIBRIM BZ OPHTHALMIC SUSPENSION out of reach of children Store at room temperature
Article Information
Written By
DETAILS Written By Srilekha. R
Medical Content Writer
Reviewed By
Dr. Sankara Babu Gorle
Medical Expert
Last Updated
12 Dec 2022