Safronac MR Tablet 10'S
Key Information
Generic Name
Generic Name Aceclofenac 100 mg+Chlorzoxazone 250 mg+Paracetamol 325 mg
Manufacturer
Saffron Therapeutics Pvt Ltd
Variant
10 Tablet(s) in a Strip
Country of Origin
India
Detailed Information
Introduction
SAFRONAC MR TABLET is a combination of Aceclofenac, Chlorzoxazone and Paracetamol which belongs to the group of medicines called Analgesics and Muscle relaxants respectively. It is used to manage muscular pains and spasms. It can also be used to provide relief from joint pain (Ex. osteoarthritis, rheumatoid arthritis) and back pain (Ex. ankylosing spondylitis). Take SAFRONAC MR TABLET preferably with meals to avoid gut irritation. Avoid consumption of alcohol as it could aggravate the risk of stomach problems. Do not take SAFRONAC MR TABLET if you have any ulcers, bleeding or perforations in the gut. Before taking SAFRONAC MR TABLET inform your doctor if you have any liver, kidney or heart problems. You must also inform your doctor if you have diabetes, hypertension, high blood cholesterol, any inflammation in the bowel or intestines, blood clots, bleeding problems or a previous history of stomach ulcers as a precaution. SAFRONAC MR TABLET is not recommended for use in patients with liver failure or stroke. It is also not suitable for use in pregnant or breastfeeding women. The most common
Uses
OF SAFRONAC MR TABLETIt is used to manage: Muscle pain and spasms Joint pain and back pain
How It Works
SAFRONAC MR TABLET contains three medicines namely Chlorzoxazone, Aceclofenac and paracetamol. Chlorzoxazone is a muscle relaxant. It acts by increasing the effects of certain chemical messengers (such as GABA) in the brain and in spinal cord that induces muscle relaxation. As a result, it manages muscle twitching, relieves pain caused due to muscle spasms and improves muscle movement. Aceclofenac and paracetamol are analgesic agents. They provide pain relief by blocking the release of certain chemicals (such as prostaglandins) in the body that causes pain, inflammation and swelling. Collectively, these action helps in reducing muscle spasms, joint pain and inflammation.
Directions for Use
Take SAFRONAC MR TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. It is preferably taken with meals to avoid gastric irritation. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition.
Side Effects
taking SAFRONAC MR TABLET are nausea, vomiting, indigestion, heartburn and stomach pain. Consult your doctor if any of these side effect worsens. USES OF SAFRONAC MR TABLETIt is used to manage: Muscle pain and spasms Joint pain and back pain HOW SAFRONAC MR TABLET WORKSSAFRONAC MR TABLET contains three medicines namely Chlorzoxazone, Aceclofenac and paracetamol. Chlorzoxazone is a muscle relaxant. It acts by increasing the effects of certain chemical messengers (such as GABA) in the brain and in spinal cord that induces muscle relaxation. As a result, it manages muscle twitching, relieves pain caused due to muscle spasms and improves muscle movement. Aceclofenac and paracetamol are analgesic agents. They provide pain relief by blocking the release of certain chemicals (such as prostaglandins) in the body that causes pain, inflammation and swelling. Collectively, these action helps in reducing muscle spasms, joint pain and inflammation. DIRECTIONS FOR USETake SAFRONAC MR TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. It is preferably taken with meals to avoid gastric irritation. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition. SIDE EFFECTS OF SAFRONAC MR TABLETCOMMON nausea, vomiting heartburn, stomach pain, diarrhea, constipation loss of appetite, indigestion tiredness, sleepiness dizziness, spinning sensation UNCOMMON mouth ulcers skin rash or itching bloating RAREStop taking SAFRONAC MR TABLET and consult your doctor immediately if you experience any of the following: signs of severe allergic reactions (such as skin rash, itching, swelling of the face, lips, throat or tongue causing difficulty in breathing or swallowing, chest tightness, fever, ulcers on the mucous membrane, oral sores) signs of liver problem (such as fever, skin rash, lack of appetite, nausea, vomiting, fatigue, upper abdominal pain, dark urine, yellowing of skin and whites of the eye) severe skin reactions (such as skin rash with itching and redness, blistering and peeling of skin, skin swelling and inflammation of mucous membrane, joint pain with fever) bloody stools, vomits or urine difficulty in passing urine, painful urination bleeding or bruising
Warnings & Precautions
& PRECAUTIONSPREGNANCYSAFRONAC MR TABLET is not recommended for use in pregnant women. Therefore, consult your doctor before taking it. BREASTFEEDINGSAFRONAC MR TABLET is not recommended for use in breastfeeding women. Therefore, consult your doctor before taking it. DRIVING AND USING MACHINESDo not drive or operate any heavy tools or machines if you experience dizziness, drowsiness or vision problems after taking SAFRONAC MR TABLET. ALCOHOLAvoid consumption of alcohol while taking SAFRONAC MR TABLET as it may make you feel dizzier or drowsier. KIDNEYSAFRONAC MR TABLET is not recommended for use in patients with moderate to severe kidney diseases. It should be used with caution in patients with mild kidney problems. Therefore, consult your doctor before taking it. LIVERSAFRONAC MR TABLET is not recommended in patients with severe liver problems (such as liver failure). It should be used with caution in patients with mild liver problems. Therefore, consult your doctor before taking it. ALLERGYDo not take SAFRONAC MR TABLET if you are allergic to Aceclofenac, Chlorzoxazone or Paracetamol. LUNGSSAFRONAC MR TABLET is not recommended for use in patients who previous experienced asthma attack or breathing difficulties after taking any pain-relieving medicine. HEART DISEASESAFRONAC MR TABLET is not recommended for use in patients with severe heart problems (such as heart attack). It should be used with caution in patients with other heart problems (such as angina). Therefore, consult your doctor before taking it. OTHERSSAFRONAC MR TABLET is not recommended for use if you: have GI bleeding (bloody stools or vomits) have ulcers in the stomach or intestines have stroke or any problems in blood circulation have any blood clotting disorders Before taking SAFRONAC MR TABLET inform your doctor if you: have porphyria have diabetes have high blood pressure have blood cholesterol levels have inflammation of the bowel (Ex. Ulcerative colitis, Crohn’s Disease) have holes or blockage in the gut have a history of stomach ulcers have any autoimmune disorders that affects the skin (Systemic lupus erythematosus) smoke have blood clots in the body have bleeding problems recently had any surgery have chickenpox Use in Pediatrics: SAFRONAC MR TABLET is not recommended for use in children and adolescents (aged below 18 years) unless considered necessary by the physician. Therefore, consult your doctor for advice before taking it. Use in Geriatrics: SAFRONAC MR TABLET should be used with caution in elderly patients. Therefore, consult your doctor for advice before taking it.
Drug Interactions
SA. Drug-Drug Interactions: Before taking SAFRONAC MR TABLET, inform your doctor if you are taking any of the following medicines such as: other medicines used to manage pain (Ex. aspirin, ibuprofen, naproxen, celecoxib, etoricoxib) medicines used to manage increased blood pressure (Ex. enalapril, lisinopril, losartan, candesartan, methyldopa, clonidine, propranolol) diuretics (used to reduce edema and blood pressure) Ex. furosemide, hydrochlorothiazide cardiac glycosides (used to correct heart rhythm (Ex. digoxin) medicines used to suppress immune system after organ transplantation (Ex. ciclosporin or tacrolimus) medicines used to stop blood clotting (Ex. warfarin, heparin, clopidogrel) cholestyramine (a medicine used to control blood cholesterol levels) corticosteroids (used to manage pain and inflammation) Ex. hydrocortisone, prednisolone medicines used to manage nausea and vomiting (Ex. domperidone, metoclopramide) chloramphenicol (a medicine used to manage bacterial infections) medicines used to manage infections (Ex. ciprofloxacin, ofloxacin, levofloxacin, moxifloxacin) medicines used to manage depression (Ex. citalopram, escitalopram, fluoxetine, fluvoxamine, paroxetine and sertraline) medicines used to manage cancer and autoimmune disorders such as arthritis and skin conditions (Ex. methotrexate) medicines used to manage HIV infection (Ex. zidovudine) medicines used to manage diabetes (Ex. glibenclamide, gliclazide, tolbutamide) Overdosage: If you or anyone else accidentally took more SAFRONAC MR TABLET, visit the nearby hospital or consult your doctor immediately. SYNOPSIS Drug : Aceclofenac, Chlorzoxazone, Paracetamol Pharmacological Category : COX-2 inhibitor, Mephensin Congeners, Analgesics and Antipyretics Therapeutic Indication : Muscle Pain, Joint Pain Dosage Forms : Tablet MORE INFORMATION Keep SAFRONAC MR TABLET out of reach of children Store SAFRONAC MR TABLET below 25°C
Article Information
Written By
DETAILS Written By Srilekha. R
Medical Content Writer
Reviewed By
Dr. Sankara Babu Gorle
Medical Expert
Last Updated
15 Nov 2022