SAFION 100 Tablet 10's

Parkinsonism (115)Rx required

Key Information

Generic Name

Generic Name Safinamide 100 mg

Manufacturer

Intas Pharmaceuticals Ltd

Variant

10 Tablet(s) in a Strip

Country of Origin

India

Detailed Information

Introduction

SAFION 100 TABLET contains Safinamide which belongs to the group of medicines called Monoamine oxidase type B (MAO-B) inhibitors. SAFION 100 TABLET is used in the management of Parkinson’s disease, which is an age-related degenerative brain condition that cause unintended/uncontrollable movements in adults. SAFION 100 TABLET is also used to manage Parkinson’s disease in mid-late-stage patients when used with Levodopa or in combination with other anti-Parkinson’s disease. SAFION 100 TABLET is not recommended for use in patients allergic to Safinamide. It is also not recommended for use in patients suffering from eye condition (due to albinism, retinal degeneration, uveitis, inherited retinopathy), and/or severe liver problems. Before taking SAFION 100 TABLET, inform your doctor if you have kidney problems (such as renal impairment), and/or other liver problems (such as mild to moderate hepatic impairment). SAFION 100 TABLET is not recommended for use during pregnancy and in women planning for pregnancy. It is also not recommended for use in breastfeeding women as it may pass through breast milk. SAFION 100 TABLET is not recommended for use in children and adolescents (aged below 18 years) and is advised to be used with caution in elderly patients (aged 75 years/above) after consulting the doctor. The most common

Uses

OF SAFION 100 TABLET Manage Parkinson’s disease in adults

How It Works

SAFION 100 TABLET works by increasing the level of a substance called dopamine (responsible for the control of movement) in the brain which generally occurs in low levels in patient affected with Parkinson’s disease.

Directions for Use

Take SAFION 100 TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.

Side Effects

taking SAFION 100 TABLET are insomnia (sleeplessness), difficulty in performing voluntary movements, feeling sleepy/dizzy/falling, headache, clouding of eye lens, drop in blood pressure (while raising to a standing position), and/or nausea. Consult your doctor if any of these side effects worsens. USES OF SAFION 100 TABLET Manage Parkinson’s disease in adults HOW SAFION 100 TABLET WORKSSAFION 100 TABLET works by increasing the level of a substance called dopamine (responsible for the control of movement) in the brain which generally occurs in low levels in patient affected with Parkinson’s disease. DIRECTIONS FOR USETake SAFION 100 TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition. SIDE EFFECTS OF SAFION 100 TABLETCOMMON insomnia (sleeplessness) difficulty in performing voluntary movements feeling sleepy/dizzy/falling headache worsening of Parkinson’s disease clouding of the eye lens drop in blood pressure while raising to a standing position nausea UNCOMMON urine infection skin cancer seeing things that are not there, feeling sad, abnormal dreams, fear, worry, confusion, mood swings increased interest in sex, abnormal thinking & perception, restlessness, sleep disorder, numbness, unsteadiness, loss of sensation, sustained abnormal muscle contraction head discomfort, trouble speaking, memory impairment fainting blurred vision, blind spot, double vision, light sensitivity, disorders of the light sensitive layer at the back of your eye, red eyes, increased pressure in the eye sensation of room spinning, throbbing sensation, fast, slow or irregular heartbeat, high or low blood pressure, large and twisted veins cough, trouble breathing, runny nose constipation, heartburn, vomiting, dry mouth, diarrhoea, stomach pain, burning stomach, gas, feeling full, drooling, decreased or increased appetite mouth ulcer sweating, itching, red skin back/joint pain, cramps, stiffness, pain in legs/arms, muscle weakness sensation of heaviness increased urination at night, painful urination, trouble having sex in males extreme tiredness, feeling weak unsteady walking swelling of your feet pain feeling hot weight loss/gain foot fracture RARE pneumonia, skin or tooth infection, viral infection sore throat, nasal allergy non-cancerous skin conditions/growth severe loss of weight uncontrollable urges, clouded consciousness, disorientation, wrong perception of images, reduced interest in sex, thoughts that you cannot get rid of, sensing that someone is out to get you premature ejaculation, uncontrollable urge to sleep, fear of social situations, suicidal thoughts, clumsiness, easy distraction loss of taste weak/slow reflexes scattering pain in the legs, continuous desire to move your legs feeling sleepy eye abnormalities, progressive weakening of vision due to diabetes, increased tears, night blindness, cross eyed heart attack, narrowing of blood vessel, tightening of the chest difficult/painful swallowing, peptic ulcer, retching, stomach bleeding jaundice loss of hair, blister, skin allergy, skin conditions, bruising, scaly skin, night sweats, painful skin, discoloration of the skin, psoriasis inflammation of spinal joints due to an autoimmune disorder pain in your sides, swelling of joints, musculoskeletal/muscular/neck/joint pain, cyst in the joint uncontrollable urge to urinate, increased urination, pus cells in urine, urinary hesitation prostate problem breast pain increased effect of the medicine, medicine intolerance feeling cold/unwell, fever dryness of skin, eye and mouth heart murmur bruising/swelling after injury blood vessel obstruction due to fat, head/mouth/skeletal injury Stop taking SAFION 100 TABLET and contact your doctor immediately if you experience any of the following side effects: signs of hypertensive crisis (sudden severe increase in blood pressure) such as anxiety, blurred vision, seizures, and/or collapse signs of neuroleptic malignant syndrome (life threatening neurologic reaction to antipsychotic medicine) such as confusion, sweating, muscle rigidity, and/or high body temperature) serotonin syndrome (serious drug reaction) such as confusion, hypertension, stiff muscles, and/or hallucinations hypotension (low blood pressure)

Warnings & Precautions

& PRECAUTIONSPREGNANCYSAFION 100 TABLET is not recommended for use during pregnancy and in women planning for pregnancy. Women of childbearing potential should use effective contraceptive measures while taking SAFION 100 TABLET. Consult your doctor before taking the medicine. BREASTFEEDINGSAFION 100 TABLET is not recommended for use in breastfeeding women as it is likely to be excreted in breast milk. Consult your doctor before taking the medicine. DRIVING AND USING MACHINESDo not drive or operate machines if you feel excess sleepiness/dizzy after taking SAFION 100 TABLET. KIDNEYSAFION 100 TABLET should be used with caution in patients with kidney problems such as renal impairment. Consult your doctor before taking SAFION 100 TABLET. LIVERSAFION 100 TABLET is not recommended for use if patients with severe liver problems. It should be used with caution in patients with mild to moderate hepatic impairment. Consult your doctor before taking SAFION 100 TABLET. ALLERGYDo not take SAFION 100 TABLET if you are allergic to Safinamide, and/or any other ingredients of this medicine. OTHERSSAFION 100 TABLET is not recommended for use if you: suffer from eye condition due to albinism (condition marked by lesser pigment in skin and eyes), retinal degeneration (loss of cells from light sensitive layer at the back of the eye), uveitis (inflammation of eye), inherited retinopathy (inherited vision disorders), and/or severe progressive diabetic retinopathy (progressive reduction of vision due to diabetes). Use in Pediatrics: SAFION 100 TABLET is not recommended for use in children and adolescents (aged below 18 years) due to lack of data on safety and efficacy of the medicine. Consult your doctor before administering the medicine to the child. Use in Geriatrics: SAFION 100 TABLET should be used with caution in elderly patients (aged 75 years/above). Consult your doctor before taking the medicine.

Drug Interactions

SA. Drug - Drug interactions: Before taking SAFION 100 TABLET, inform your doctor if you are taking any of the following medicines: monoamine oxidase (MAO) inhibitors (medicines used to manage depression) Ex. selegiline, rasagiline, moclobemide, phenelzine, isocarboxazid, tranylcypromine pethidine (used to relieve severe pain) medicines used to manage cold/cough (Ex. dextromethorphan, ephedrine, pseudoephedrine) medicines used to manage anxiety and some personality disorders (Ex. fluoxetine, fluvoxamine) medicines used to manage major depression and other mood disorders (Ex. venlafaxine, duloxetine) medicines used in high cholesterol (Ex. rosuvastatin, pitavastatin, pravastatin) medicines used to manage bacterial infections (Ex. ciprofloxacin) medicines that affect the immune system (Ex. methotrexate) medicines used to manage metastatic carcinoma (Ex. topotecan) medicine used to manage pain and inflammation (Ex. diclofenac) medicines used to manage type 2 diabetes (Ex. glyburide, metformin) medicines used to manage viral infection (Ex. acyclovir, ganciclovir) Overdosage: If you or anyone else accidentally take too much of SAFION 100 TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose are raised blood pressure, anxiety, confusion, forgetfulness, sleepiness, lightheadedness, nausea, vomiting, dilated pupils, and/or involuntary jerky movements. SYNOPSIS Drug : Safinamide Pharmacological Category : Monoamine oxidase type B (MAO-B) inhibitors Therapeutic Indication : Parkinson’s disease Dosage Forms : Tablet MORE INFORMATION Keep SAFION 100 TABLET out of reach of children Store SAFION 100 TABLET at room temperature

Article Information

DW

Written By

DETAILS Written By Dr. K .AZEEM HUSSAIN

Medical Content Writer

DS

Reviewed By

Dr. Sankara Babu Gorle

Medical Expert

Last Updated

15 Dec 2022

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#parkinsonism (115)#generic name safinamide 100 mg