RTSUNATE 60 Injection 1's
Key Information
Generic Name
Generic Name Artesunate 60 mg
Manufacturer
Themis Pharmaceutical Ltd
Country of Origin
India
Detailed Information
Introduction
INTRODUCTION ABOUT RTSUNATE 60 INJECTIONRTSUNATE 60 INJECTION contains Artesunate which belongs to the group of medicines called Antimalarials. It is used for the management of severe malaria including cerebral malaria in adult and paediatric patients. Also, it can also be used against quinine resistance. Malaria is mosquito-borne acute febrile disease caused by a protozoan named Plasmodium falciparum. It is characterized by symptoms such as high fever, chills, sweating, headache, muscle pain, nausea, vomiting, body aches, weakness, agitation, confusion, fainting on standing up and anaemia (reduced red blood cell count). Cerebral malaria is the most severe neurological complication of Plasmodium falciparum malaria which may also cause coma. RTSUNATE 60 INJECTION is not recommended for use if you have previous history of allergic reactions to artesunate or artemisinin derivatives. Before receiving RTSUNATE 60 INJECTION inform your doctor if you liver or kidney problems or any other problems. RTSUNATE 60 INJECTION is not recommended for use during first trimester of pregnancy. It should be used with caution in breastfeeding women. Consult your doctor before receiving RTSUNATE 60 INJECTION. RTSUNATE 60 INJECTION should be used with caution in children. Consult your child’s doctor for advice before administration of RTSUNATE 60 INJECTION to your child. The most common
Uses
OF RTSUNATE 60 INJECTION Manage severe malaria including cerebral malaria
How It Works
RTSUNATE 60 INJECTION helps in managing malaria where Artesunate works by transforming into a metabolite and binds with iron component of blood and forms free radicals which inhibit the synthesis of protein and nucleic acid in Plasmodium parasites and manages it from invading red blood cells, thus managing the malaria effectively.
Directions for Use
RTSUNATE 60 INJECTION will be given to you only by a doctor or a nurse intravenously (into the vein) or intramuscularly (into the muscle). Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
Side Effects
RTSUNATE 60 INJECTION are dizziness, light-headedness, headache, rash, hair loss, taste alteration (metallic/bitter taste), nausea, vomiting, abdominal pain and diarrhoea. Inform your doctor if any of these side effects bothers you. USES OF RTSUNATE 60 INJECTION Manage severe malaria including cerebral malaria HOW RTSUNATE 60 INJECTION WORKSRTSUNATE 60 INJECTION helps in managing malaria where Artesunate works by transforming into a metabolite and binds with iron component of blood and forms free radicals which inhibit the synthesis of protein and nucleic acid in Plasmodium parasites and manages it from invading red blood cells, thus managing the malaria effectively. DIRECTIONS FOR USERTSUNATE 60 INJECTION will be given to you only by a doctor or a nurse intravenously (into the vein) or intramuscularly (into the muscle). Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition. SIDE EFFECTS OF RTSUNATE 60 INJECTIONCOMMON dizziness, light-headedness tinnitus (with or without reduced hearing capability) headache, insomnia rash hair loss taste alteration (metallic/ bitter taste) nausea, vomiting, abdominal pain, loss of appetite and diarrhoea cough or nasal symptoms joint pain, muscle disorders fatigue, malaise, fever pain at injection site UNCOMMON rhythm and conduction disorders hypersensitivity RARE arterial ischemia, hypertensive retinopathy inflammation of pancreas hepatitis, calculous cholecystitis Stop receiving RTSUNATE 60 INJECTION and inform your doctor if you experience any of the following side effects: severe allergic reactions such as urticaria or generalized rash, shortness of breath, low blood pressure
Warnings & Precautions
& PRECAUTIONSPREGNANCYRTSUNATE 60 INJECTION is not recommended for use during first trimester of pregnancy. Consult your doctor before receiving RTSUNATE 60 INJECTION. BREASTFEEDINGRTSUNATE 60 INJECTION should be used with caution in breastfeeding women. Consult your doctor before receiving RTSUNATE 60 INJECTION. KIDNEYNo dose adjustment is needed for patients with kidney impairment. Consult your doctor before receiving RTSUNATE 60 INJECTION. LIVERNo dose adjustment is needed for patients with liver impairment. Consult your doctor before receiving RTSUNATE 60 INJECTION. ALLERGYDo not receive RTSUNATE 60 INJECTION if you are allergic to artesunate or artemisinin derivatives or any other ingredients of this medicine. OTHERSUse in Paediatrics RTSUNATE 60 INJECTION should be used with caution in children. Consult your child’s doctor for advice before administration of RTSUNATE 60 INJECTION to your child.
Drug Interactions
SA. Drug-Drug Interactions Before receiving RTSUNATE 60 INJECTION, inform your doctor, if you are taking any of the following medicines: nevirapine or ritonavir (medicines used to manage HIV infection) rifampin (used to manage tuberculosis) carbamazepine, phenytoin (medicines used to manage fits) axitinib, vandetanib, imatinib (medicines used to manage cancer) diclofenac (used to manage pain) Overdosage: RTSUNATE 60 INJECTION will be given to you only by a doctor or nurse in a hospital, and so it is unlikely to receive an overdose. In case of overdose you may experience seizures, dark stools, low levels of blood cells and multiorgan failure. SYNOPSIS Drug : Artesunate Pharmacological Category : Artemisinin derivative Therapeutic Indication : Severe malaria including falciparum malaria, cerebral malaria Dosage Forms : Injection, Infusion, Tablet MORE INFORMATION Store at room temperature
Article Information
Written By
DETAILS Written By Dr. R. Dinesh John Rajkumar
Medical Content Writer
Reviewed By
Dr. Sankara Babu Gorle
Medical Expert
Last Updated
15 Nov 2022