REVOLADE 50mg Tablet 2x7's
Key Information
Generic Name
Generic Name Eltrombopag 50 mg
Manufacturer
Novartis Healthcare Pvt Ltd
Variant
2 Tablet(s) in a Strip
Country of Origin
United Kingdom
Detailed Information
Introduction
REVOLADE 50MG TABLET contains Eltrombopag which belongs to the group of medicines called Thrombopoietin-receptor agonist. REVOLADE 50MG TABLET is used to manage immune thrombocytopenia (platelet disorder) in patients aged 1-year/above when other medicines (such as corticosteroids/immunoglobulins) become ineffective to manage the disease. REVOLADE 50MG TABLET is also used to manage thrombocytopenia (low platelet count) in adults suffering from hepatitis C (viral) infection. The medicine is also indicated for use to manage low blood counts in adults suffering from severe aplastic anemia (rare blood disorder that occurs due to failure of bone marrow to produce new blood cells). REVOLADE 50MG TABLET is not recommended for use in patients allergic to Eltrombopag. Before taking REVOLADE 50MG TABLET, inform your doctor if you are at a risk of developing blood clot in veins/arteries, and/or have cancer, obesity, advanced chronic liver disease, and/or kidney problems (such as renal impairment). REVOLADE 50MG TABLET is generally not recommended for use during pregnancy unless it is clearly necessary. Women of childbearing potential should use effective contraceptive measures while in management with REVOLADE 50MG TABLET. It is also not recommended for use in breastfeeding women since it is not known whether the medicine may pass through breastmilk. REVOLADE 50MG TABLET is not recommended for use in children (aged below 1-year) suffering from immune thrombocytopenia. It is also not recommended for use in children (aged below 18 years) suffering from low platelet counts due to hepatitis C/severe aplastic anemia. The medicine is advised to be used with caution in elderly patients (aged 65 years/above) after taking the medicine. The most common
Uses
OF REVOLADE 50MG TABLET Manage immune thrombocytopenia (platelet disorder) Manage thrombocytopenia in adults suffering from hepatitis C (viral) infection Manage low blood count in adults suffering from severe aplastic anemia (rare blood disorder caused due to bone marrow failure to produce new blood cells)
How It Works
REVOLADE 50MG TABLET works by binding and activating thrombopoietin receptor protein (molecules responsible for regulating platelet production) which helps in activating the pathways within the cells to increase production and development of bone marrow progenitor cells (membrane bound units responsible for producing all types of cell in bone marrow) which results in increased production of platelet cells in patients affected with immune thrombocytopenia bleeding disorder associated with/without hepatitis C or severe aplastic anemia.
Directions for Use
Take REVOLADE 50MG TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight, and disease condition.
Side Effects
taking REVOLADE 50MG TABLET are common cold, cough, nausea, vomiting, diarrhea, constipation, and/or hair loss. Consult your doctor if any of these symptoms worsens. USES OF REVOLADE 50MG TABLET Manage immune thrombocytopenia (platelet disorder) Manage thrombocytopenia in adults suffering from hepatitis C (viral) infection Manage low blood count in adults suffering from severe aplastic anemia (rare blood disorder caused due to bone marrow failure to produce new blood cells) HOW REVOLADE 50MG TABLET WORKSREVOLADE 50MG TABLET works by binding and activating thrombopoietin receptor protein (molecules responsible for regulating platelet production) which helps in activating the pathways within the cells to increase production and development of bone marrow progenitor cells (membrane bound units responsible for producing all types of cell in bone marrow) which results in increased production of platelet cells in patients affected with immune thrombocytopenia bleeding disorder associated with/without hepatitis C or severe aplastic anemia. DIRECTIONS FOR USETake REVOLADE 50MG TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight, and disease condition. SIDE EFFECTS OF REVOLADE 50MG TABLETCOMMON common cold, cough, cold sore, irritation/infection and swelling of sinus/tonsils, itchy/runny/blocked nose, bleeding nose, nasal congestion/sneezing loss of appetite, abdominal pain, nausea, vomiting, diarrhea, constipation, bloating, gas infection in the nose, sinuses, throat, and upper airways back pain, bone pain, ear pain, nose/throat pain, toothache muscle pain/spasm/weakness heavy menstrual period sore throat and discomfort while swallowing eye problems including dry eye, cataract, spots/deposits in eye, yellowing of white of eye, itchy eye, blurred vision, and/or eye pain flu (influenza), pneumonia, infection of lungs, nose, and throat mouth problems (including dry mouth, sore mouth, sensitive tongue, bleeding gums, mouth ulcers, blisters in mouth), inflammation of gum tissue tingling/prickling/numbness sensation decreased skin sensations signs of blood clot in deep vein such as pain, swelling, and tenderness in one of your legs hematoma (localized swelling filled with blood due to break in blood vessel) hot flushes toothache skin changes including excessive sweating, itching bumpy rash, red spots, and/or changes in appearance of the skin hair loss signs of proteinuria (protein in urine) such as foamy, frothy, or bubbly-looking urine high temperature, feeling hot weakness, dizziness, drowsiness, tiredness, fever, chills, general discomfort swelling in hands/feet sleeping problems, anxiety, depression, migraine (headache) decreased vision spinning sensation (vertigo) gas UNCOMMON allergic reaction interruption of blood to supply to parts of heart signs of blood clot in lungs such as sudden shortness of breath, sharp pain in chest, and/or rapid breathing blockade in lung artery signs of blood clot in a vein such as possible pain, swelling, and/or redness around a vein blockage in the bile tract (yellowing of the skin and/or abdominal pain) liver damage liver injury signs of disorder related to the heart and the blood vessels such as heart beating faster, irregular heartbeat, bluish discoloration of the skin, and/or disturbances of heart rhythm gout mood changes, lack of interest, crying at unexpected times, problems with balance, speech and nerve function, shaking painful/abnormal skin sensations paralysis on one side of the body nerve damage dilation/swelling of blood vessels that cause headache eye problems such as bleeding of retina digestive system problems including frequent bowel movements, food poisoning, blood in stool, vomiting of blood rectal bleeding sunburn redness/swelling around a wound bleeding around a catheter (if present) into the skin sensation of a foreign body signs of kidney problems such as inflammation of the kidney, excessive urination at night, and/or kidney failure changes in the shape of the red blood cells infection of the skin skin changes including skin discoloration, peeling, redness, itching, and/or sweating cancer of the rectum and colon RAREStop taking REVOLADE 50MG TABLET and contact your doctor immediately if you experience any of the following side effects: signs of blood clot such as swelling/pain/tenderness in one leg, sudden shortness of breath (associated with sharp pain in the chest), rapid breathing, stomach pain, enlarged abdomen, and/or blood in stools signs of liver problems such as yellowing of skin/ whites of the eyes (jaundice), dark-colored urine signs of bleeding in the digestive system such as vomiting blood, black tarry stools, and/or blood in stools
Warnings & Precautions
& PRECAUTIONSPREGNANCYREVOLADE 50MG TABLET is generally not recommended for use during pregnancy unless it is clearly necessary. Women of childbearing potential should use effective contraceptive measures while in management with REVOLADE 50MG TABLET. Consult your doctor before taking the medicine. BREASTFEEDINGREVOLADE 50MG TABLET is not recommended for use in breastfeeding women since it is not known whether the medicine may pass through breastmilk. Consult your doctor before taking the medicine. DRIVING AND USING MACHINESDo not drive or operate any machines if you feel dizzy or less alert after taking REVOLADE 50MG TABLET. KIDNEYREVOLADE 50MG TABLET should be taken with caution in patients with kidney problems such as renal impairment. Consult your doctor before taking REVOLADE 50MG TABLET. LIVERREVOLADE 50MG TABLET should be used with caution in patients suffering from advanced chronic liver disease only if necessary, since the medicine may increase the risk of occurrence of side effects/blood clot. Consult your doctor before taking REVOLADE 50MG TABLET. ALLERGYDo not take REVOLADE 50MG TABLET if you are allergic to Eltrombopag, and/or any other ingredients of this medicine. OTHERSBefore taking REVOLADE 50MG TABLET, inform your doctor if you: are at a risk of developing blood clot in veins/arteries are suffering from cancer recently undergone surgery had a physical injury are obese are a smoker have cataract (eye lens getting cloudy) suffer from another blood condition such as s myelodysplastic syndrome Use in Pediatrics: REVOLADE 50MG TABLET is not recommended for use in children (aged below 1-year) suffering from immune thrombocytopenia (platelet disorder). It is also not recommended for use in children (aged below 18 years) suffering from low platelet counts due to hepatitis C/severe aplastic anemia. Consult your doctor before taking REVOLADE 50MG TABLET. Use in Geriatrics: REVOLADE 50MG TABLET should be used with caution in elderly patients (aged 65-years/above). Consult your doctor before taking REVOLADE 50MG TABLET.
Drug Interactions
SA. Drug-Drug interactions: Before taking REVOLADE 50MG TABLET inform your doctor if you are taking any of the following medicine: a blood thinner antacids (used in indigestion, stomach ulcers/heartburn) Ex. aluminum hydroxide, magnesium carbonate statins (used to manage high cholesterol) Ex. atorvastatin, fluvastatin lopinavir, ritonavir (medicines used to manage HIV) ciclosporin (used to manage rejection of transplanted organ) vitamins and mineral supplements such as iron, calcium, aluminum, magnesium, selenium, and zinc methotrexate, topotecan (medicines used to manage cancer) corticosteroids (used to provide relief from inflammation) Ex. cortisone, hydrocortisone danazol (used to manage endometriosis) azathioprine (used for inflammatory conditions) B. Drug-food interaction: Avoid taking REVOLADE 50MG TABLET with dairy foods/drinks since calcium in dairy products may affect the absorption of the medicine and alter its effect. Overdosage: If you or anyone else accidentally take too much of REVOLADE 50MG TABLET, consult your doctor immediately or visit the nearby hospital to manage overdose symptoms. SYNOPSIS Drug : Eltrombopag Pharmacological Category : Thrombopoietin-receptor agonist Therapeutic Indication : Immune thrombocytopenia, thrombocytopenia with hepatitis C virus infection/aplastic anemia Dosage Forms : Tablet MORE INFORMATION Keep REVOLADE 50MG TABLET out of reach of children Store REVOLADE 50MG TABLET at room temperature
Article Information
Written By
DETAILS Written By Dr. K .AZEEM HUSSAIN
Medical Content Writer
Reviewed By
Dr. Sankara Babu Gorle
Medical Expert
Last Updated
19 Dec 2022