Resof Total Tablet 28'S
Key Information
Generic Name
Generic Name Sofosbuvir 400 mg+Velpatasvir 100 mg
Manufacturer
Dr. Reddy's Laboratories Ltd
Variant
28 Tablet(s) in a Strip
Country of Origin
India
Detailed Information
Introduction
RESOF TOTAL TABLET is a combination of Sofosbuvir and Velpatasvir which belongs to the group of medicines called Antiviral agents. It is used to manage chronic (long-term) Hepatitis C infection. Hepatitis C infection is a viral infection caused due to hepatitis C virus. It predominantly affects the liver and ca
Uses
severe liver damage. It spreads mostly through contact with blood from an infected person (such as through sharing needles). RESOF TOTAL TABLET is suitable for use both in adults and in children (aged 3 years or above). Before taking RESOF TOTAL TABLET inform your doctor if you have diabetes, kidney problems or any other liver problems apart from hepatitis C infection (such as liver transplant or hepatitis B infection). Do not take RESOF TOTAL TABLET without consulting your doctor if you are pregnant or breastfeeding. During management with RESOF TOTAL TABLET, your doctor will regularly monitor your blood sugar levels and blood count to access improvement in your health condition and to avoid the risk of unwanted
How It Works
RESOF TOTAL TABLET is an antiviral agent. It acts by blocking the actions of certain viral enzymes (HIV-reverse transcriptase) that is required for the viral cell to grow and multiply. As a result, it controls the multiplication of harmful viral cells within the body which reduces the severity of the infection.
Directions for Use
Take RESOF TOTAL TABLET as directed by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. RESOF TOTAL TABLET can be taken with or without meals. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and severity of the infection. Do not stop taking RESOF TOTAL TABLET without consulting your doctor as it may reduce its effectiveness.
Side Effects
taking RESOF TOTAL TABLET are headache, tiredness and skin rashes. Consult your doctor if they trouble you. USES OF RESOF TOTAL TABLET Manage chronic Hepatitis C infection HOW RESOF TOTAL TABLET WORKSRESOF TOTAL TABLET is an antiviral agent. It acts by blocking the actions of certain viral enzymes (HIV-reverse transcriptase) that is required for the viral cell to grow and multiply. As a result, it controls the multiplication of harmful viral cells within the body which reduces the severity of the infection. DIRECTIONS FOR USETake RESOF TOTAL TABLET as directed by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. RESOF TOTAL TABLET can be taken with or without meals. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and severity of the infection. Do not stop taking RESOF TOTAL TABLET without consulting your doctor as it may reduce its effectiveness. SIDE EFFECTS OF RESOF TOTAL TABLETCOMMON headache tiredness skin rash RAREStop taking RESOF TOTAL TABLET and contact your doctor immediately if you experience any of the following side effects: signs of allergic reactions (such as skin rash, itching, swelling of the face, lips, nose, throat which causes difficulty in breathing or swallowing) severe skin reactions causing widespread skin rashes with severe itching, blistering and peeling of skin, accompanied with fever, flu-like symptoms and ulcers in the mouth, eyes and/or genitals)
Warnings & Precautions
& PRECAUTIONSPREGNANCYThere is no proper information regrading the use of RESOF TOTAL TABLET during pregnancy. Therefore, if you are pregnant or think you may be pregnant, consult your doctor before taking this medicine. Pregnancy should be avoided if this medicine is combined with another antiviral agent known as ribavirin. BREASTFEEDINGRESOF TOTAL TABLET may pass through the breast milk. Therefore, it is not recommended for use in breastfeeding women. Consult your doctor for advice before taking it. DRIVING AND USING MACHINESDo not drive or handle any machines if your ability is affected by RESOF TOTAL TABLET. KIDNEYRESOF TOTAL TABLET should be used with caution in patients with kidney problems (such as dialysis). Therefore, consult your doctor before taking it. LIVERRESOF TOTAL TABLET should be used with caution in patients with other liver problems apart from hepatitis C infection such as awaiting a liver transplant or hepatitis B infection. Therefore, consult your doctor before taking it. ALLERGYDo not take RESOF TOTAL TABLET if you are allergic to Velpatasvir or Sofosbuvir. HEART DISEASERESOF TOTAL TABLET should be used with caution if you have heart problems. Consult your doctor for advice. OTHERSBefore taking RESOF TOTAL TABLET, inform your doctor if you: are taking medicines for any on-going viral infections have diabetes Use in Paediatrics: RESOF TOTAL TABLET is not recommended for use in children aged below 3 years. Therefore, consult your doctor before taking it. Use in Geriatrics: RESOF TOTAL TABLET should be used with caution in elderly people. Therefore, consult your doctor before taking it.
Drug Interactions
SA. Drug - Drug interactions: Before taking RESOF TOTAL TABLET inform your doctor if you are taking any of the following medicines such as: rifampicin, rifabutin, rifapentine (used to manage tuberculosis) St. John’s wort (a medicine used to manage depression) medicines used to manage epilepsy (such as carbamazepine, phenobarbital, phenytoin, oxcarbazepine) rosuvastatin (a medicine used to manage high blood cholesterol levels) amiodarone, digoxin (used to manage irregular heart rate) warfarin, dabigatran, vitamin k antagonists (used for blood thinning) medicines used to suppress your immune system (such as tacrolimus, cyclosporine) tenofovir disoproxil fumarate, tipranavir (used to manage HIV infection) medicines used to manage stomach ulcers or heartburn (such as aluminium hydroxide, omeprazole, lansoprazole, rabeprazole, pantoprazole, esomeprazole, famotidine, cimetidine, nizatidine or ranitidine) Overdosage: If you or anyone else accidentally took more RESOF TOTAL TABLET, consult your doctor immediately. SYNOPSIS Drug : Velpatasvir, Sofosbuvir Pharmacological Category : HCV NS5A inhibitors, nucleotide polymerase inhibitors Therapeutic Indication : Hepatitis C infection Dosage Forms : Tablet MORE INFORMATION Keep RESOF TOTAL TABLET out of reach of children Store RESOF TOTAL TABLET at room temperature
Article Information
Written By
DETAILS Written By Srilekha. R
Medical Content Writer
Reviewed By
Dr. Sankara Babu Gorle
Medical Expert
Last Updated
05 Jan 2023