Rekool L 20mg Tablet 10'S
Key Information
Generic Name
Generic Name Levosulpiride 75 mg+Rabeprazole 20 mg
Manufacturer
Alembic Pharmaceuticals Ltd
Variant
10 Tablet(s) in a Strip
Country of Origin
India
Detailed Information
Introduction
REKOOL L 20MG TABLET is a combination of Levosulpiride and Rabeprazole which belongs to the group of medicines called Dopamine D2 antagonists and Proton-pump inhibitors respectively. REKOOL L 20MG TABLET is indicated for the management of Gastro-esophageal reflux disease (GERD). GERD is a chronic digestive disease in which the stomach acid frequently flows into the esophagus leading to irritation and inflammation of lining of food pipe. Symptoms include heartburn, chest pain, nausea, sensation of lump in throat and stomach discomfort. REKOOL L 20MG TABLET can also be used to manage peptic ulcer (painful sores in the gut), Zollinger-Ellison syndrome (tumors in pancreas causing the stomach to secrete more acid), functional dyspepsia (recurrent signs and symptoms of indigestion without an obvious cause) and diabetic gastroparesis (delayed gastric emptying caused due to diabetes). Levosulpiride is a dopamine D2 antagonist that reduces acid reflux by enhancing gastric emptying (propulsion of food from the stomach to the intestines) and bowel movements and rabeprazole is a proton pump inhibitor that inhibits the secretions of stomach acid, thus leading to healing of ulcers and inflammatory lesions in the stomach and in the intestines. Take REKOOL L 20MG TABLET preferably on an empty stomach. Avoid consumption of alcohol while taking REKOOL L 20MG TABLET as it could potentiate the CNS depressive
Uses
OF REKOOL L 20MG TABLET Manage Gastro-Esophageal Reflux Disease (GERD) Manage function dyspepsia Manage peptic ulcer Manage Zollinger-Ellison syndrome Manage diabetic gastroparesis
How It Works
REKOOL L 20MG TABLET reduces stomach ulcers, nausea, and acid reflux, where rabeprazole acts by inhibiting the secretions of stomach acid by blocking the proton pump (H+ K+ ATPase) at the secretory surface of gastric parietal cells and levosulpiride acts by blocking the dopamine D2 receptors in the CTZ (area in medulla oblongata that causes vomiting when stimulated) and in the gut, thus facilitating the movement of food from the stomach into the intestines followed by healing of ulcers or inflammatory lesions in the stomach and in the esophagus.
Directions for Use
Take REKOOL L 20MG TABLET on an empty stomach or as advised by your physician. Swallow REKOOL L 20MG TABLET as a whole and do not crush or chew the medicine. Your doctor will decide the correct dose and duration of therapy for you, depending upon your age, body weight and disease condition.
Side Effects
bone fracture (i.e., in the hip, wrist, or spine) which is more predominant in the patients having osteoporosis or taking corticosteroids. Before taking REKOOL L 20MG TABLET, inform your doctor if you have any heart, kidney, or liver disease as a precaution. REKOOL L 20MG TABLET is not recommended for use in pregnant or breastfeeding women and in children (below 18 years. The most common side effects of taking REKOOL L 20MG TABLET are nausea, vomiting, stomach pain, diarrhea, constipation, infections, cough, sore throat, or fatigue. Consult your doctor if any of these symptoms worsen. USES OF REKOOL L 20MG TABLET Manage Gastro-Esophageal Reflux Disease (GERD) Manage function dyspepsia Manage peptic ulcer Manage Zollinger-Ellison syndrome Manage diabetic gastroparesis HOW REKOOL L 20MG TABLET WORKSREKOOL L 20MG TABLET reduces stomach ulcers, nausea, and acid reflux, where rabeprazole acts by inhibiting the secretions of stomach acid by blocking the proton pump (H+ K+ ATPase) at the secretory surface of gastric parietal cells and levosulpiride acts by blocking the dopamine D2 receptors in the CTZ (area in medulla oblongata that causes vomiting when stimulated) and in the gut, thus facilitating the movement of food from the stomach into the intestines followed by healing of ulcers or inflammatory lesions in the stomach and in the esophagus. DIRECTIONS FOR USETake REKOOL L 20MG TABLET on an empty stomach or as advised by your physician. Swallow REKOOL L 20MG TABLET as a whole and do not crush or chew the medicine. Your doctor will decide the correct dose and duration of therapy for you, depending upon your age, body weight and disease condition. SIDE EFFECTS OF REKOOL L 20MG TABLETCOMMON infections, weakness, or flu-like symptoms difficulty in sleeping headache or dizziness cough, runny nose, or sore throat nausea, vomiting, stomach pain, diarrhea, wind (flatulence), or constipation aches or back pain benign polyps in stomach UNCOMMON nervousness, drowsiness chest infection sinusitis (painful and blocked sinuses) dryness of mouth indigestion or belching skin rash or redness leg pain, muscle pain or joint pain fractures of the spine, hip, and wrist urinary tract infection chest pain fever or chills RARE loss of appetite depression visual disturbance sore mouth, taste disturbance stomach upset or pain sweating kidney problems weight gain low blood platelet count (easy bleeding or bruising) changes in white blood cells (repeated infection) Stop taking REKOOL L 20MG TABLET and contact your doctor immediately if you experience any of the following symptoms: skin rash on sun exposed areas with joint pain severe (watery or bloody) diarrhea accompanied with fever, abdominal pain, or tenderness severe allergic reactions (such as sudden swelling of the face, leading to breathing difficulties or low blood pressure which may cause fainting or collapse) frequent infections, such as high fever or sore throat or ulcers in the mouth or throat bleeding or bruising easily severe skin blistering with oral sores signs of liver disease (yellowing of the skin and eyes, dark urine, and tiredness) signs of serious skin reactions (such as erythema multiforme, Stevens-Johnson syndrome or toxic epidermal necrolysis causing severe skin redness with blistering or peeling, bleeding in the lips, eyes, mouth, nose and genitals with a high fever and joint pains) signs of decreased magnesium levels in blood (such as fatigue, tetany, delirium, convulsions, dizziness, and ventricular arrhythmia)
Warnings & Precautions
& PRECAUTIONSPREGNANCYContraindicatedREKOOL L 20MG TABLET is not recommended for use in pregnant women. Consult your doctor before taking REKOOL L 20MG TABLET. BREASTFEEDINGContraindicatedREKOOL L 20MG TABLET is strictly not recommended for use in breastfeeding women. Consult your doctor before taking REKOOL L 20MG TABLET. DRIVING AND USING MACHINESUse with CautionDo not drive or operate any heavy tools or machines if you experience dizziness, drowsiness, or sleepiness after taking REKOOL L 20MG TABLET. ALCOHOLConsult your doctorAvoid consumption of alcohol while taking REKOOL L 20MG TABLET, as it could cause CNS depression (characterized by confusion, attention impairment, and anxiety), dizziness and/or drowsiness. Consult your doctor before taking REKOOL L 20MG TABLET. KIDNEYUse with CautionREKOOL L 20MG TABLET should be taken with caution in patients with kidney disease. Consult your doctor before taking REKOOL L 20MG TABLET. LIVERUse with CautionREKOOL L 20MG TABLET should be taken with caution in patients with a previous history of liver problems. Consult your doctor before taking REKOOL L 20MG TABLET. ALLERGYContraindicatedDo not take REKOOL L 20MG TABLET if you are allergic to Levosulpiride, Rabeprazole, or other proton-pump inhibitors (Ex. pantoprazole, omeprazole, lansoprazole). LUNGSUse with CautionREKOOL L 20MG TABLET should be taken with caution in patients with asthma or other respiratory diseases. Consult your doctor before taking REKOOL L 20MG TABLET. HEART DISEASEUse with CautionREKOOL L 20MG TABLET should be taken with caution in patients with heart disease. Consult your doctor before taking REKOOL L 20MG TABLET. USE IN PEDIATRICSContraindicatedREKOOL L 20MG TABLET is not recommended for use in children and adolescents (below 18 years). Consult your doctor before taking REKOOL L 20MG TABLET. USE IN GERIATRICSUse with CautionREKOOL L 20MG TABLET should be used with caution in elderly patients (aged 65 years or above). Consult your doctor before taking REKOOL L 20MG TABLET. Proper dose adjustments and careful monitoring are required in such patients. OTHERSREKOOL L 20MG TABLET is strictly not recommended for use if you have: Parkinson’s disease history of epilepsy Neuroleptic malignant syndrome (a CNS disorder characterized by high fever, stiffness of the muscles, altered mental status (paranoid behavior), and autonomic dysfunction) breast cancer (with high levels of prolactin in the body) Before taking REKOOL L 20MG TABLET, inform your physician if you: have a tumor in the stomach or breast have bleeding or perforation the gastrointestinal tract have or at risk of developing vitamin-B12 deficiency have had developed any skin reaction following management with similar medicines that can reduce stomach acid are due to have a specific blood test (Chromogranin A) have osteoporosis are a smoker have porphyria (a rare blood disorder) have alcohol intoxication (drinking large amount of alcohol in short period) have or had phaeochromocytoma (tumors of adrenal gland) in the past have or had prolactinoma (a noncancerous tumor of pituitary gland) in the past have hypokalemia (decreased potassium levels in blood) have neuroendocrine tumor (tumors in neuroendocrine cells) have mania or other mental disorders have painful breasts
Drug Interactions
SA. Drug-Drug interactions: Before taking REKOOL L 20MG TABLET inform to your doctor, if you are taking any of these medicines: medicines used to manage HIV infection (Ex. atazanavir, nelfinavir, saquinavir, rilpivirine) antacids (used to neutralize stomach acid secretions) Ex. aluminium hydroxide, magnesium hydroxide sucralfate (used to manage duodenal ulcer) cisapride (used to manage heart burn in patients with gastroesophageal reflux disease) anticholinergics (medicines that causes smooth muscle relaxation and decreases body secretions) Ex. atropine, scopolamine, homatropine levodopa (used for Parkinson’s disease) medicines causing low levels of potassium in blood such as furosemide (used to manage edema), corticosteroids (used to manage inflammation) Ex. cortisol, laxatives such as bisacodyl (used to manage constipation) iron salts (used to manage iron deficiency) Ex. ferrous sulphate, ferric ammonium citrate medicines used to manage high blood pressure and other heart problems (Ex. captopril, enalapril, losartan, valsartan, diltiazem, digoxin, quinidine) atomoxetine (used to manage attention-deficit hyperactivity disorder) terfenadine (used to manage allergic conditions) chloroquine (used to manage or manage malaria) clarithromycin, or amoxicillin (used to manage bacterial infections) medicines used to manage cancer (Ex. erlotinib, dasatinib, nilotinib) methotrexate (used to manage cancer and auto-immune disease) tacrolimus or mycophenolate mofetil (used to manage graft rejection) ketoconazole, itraconazole (used to manage fungal infection) warfarin (used for blood thinning and management of heart problems) pregabalin (used to manage neuropathic pain) tramadol (used to manage pain) ipratropium (used to manage symptoms of COPD/asthma) Overdosage: If you or anyone else accidentally take too much of REKOOL L 20MG TABLET, contact your doctor immediately or go to a hospital straight away. SYNOPSIS Drug : Levosulpiride, Rabeprazole Pharmacological Category : Dopamine D2 antagonists, Proton-pump inhibitors Therapeutic Indication : Peptic ulcer, GERD, Functional dyspepsia, Diabetic gastroparesis, Zollinger-Ellison syndrome Dosage Forms : Tablet, Capsule MORE INFORMATION Keep REKOOL L 20MG TABLET out of reach of children Store REKOOL L 20MG TABLET at room temperature
Frequently Asked Questions
Common questions and answers about Rekool L 20mg Tablet 10'S.
When and how should I take REKOOL L 20MG TABLET?
Take REKOOL L 20MG TABLET on an empty stomach or as advised by your physician. Swallow the medicine as a whole and do not crush or chew the medicine. Your doctor will decide the correct dose of REKOOL L 20MG TABLET and duration of therapy for you, depending upon your age, body weight and health condition.
Can REKOOL L 20MG TABLET be used in children?
REKOOL L 20MG TABLET is not recommended for use in children and adolescents (aged below 18 years). Kindly consult child’s doctor if your child experiences any symptoms of gastro-esophageal reflux disease (such as nausea, discomfort in upper stomach, heartburn, burping, etc.)
Can I consume alcohol while taking REKOOL L 20MG TABLET?
No. Avoid consumption of alcohol while taking REKOOL L 20MG TABLET, as it could cause CNS depression (characterized by confusion, attention impairment, and anxiety), dizziness and/or drowsiness. Also, if you are a chronic alcoholic or suffering from acute alcohol intoxication, please inform your doctor as a precaution before taking REKOOL L 20MG TABLET.
Can I drive while taking REKOOL L 20MG TABLET?
REKOOL L 20MG TABLET may cause dizziness in some individuals and so avoid driving or operating any tools or machines while you are feeling dizzy. Try to rest and relax. Get enough sleep. Do not consume too much of alcohol, as it can aggravate your dizziness. Consult your doctor before taking REKOOL L 20MG TABLET
Can prolong use of REKOOL L 20MG TABLET cause bone fractures?
Yes. Prolonged use of REKOOL L 20MG TABLET can increase the risk of bone fracture (particularly in the hips, wrist, or spine), particularly in the elderly patients and in patients with other risk factors such as having osteoporosis or taking corticosteroids. Consult your doctor before taking REKOOL L 20MG TABLET. During management with REKOOL L 20MG TABLET your doctor may monitor to rule out the risk of fractures. Do not take REKOOL L 20MG TABLET for a prolonged period without consulting your doctor.
What to do If I forget to take REKOOL L 20MG TABLET?
You should take REKOOL L 20MG TABLET immediately when you remember. If it is time for your next dose of REKOOL L 20MG TABLET skip the missed dose and follow your regular dose schedule. Do not double the dose to match up your missed dose.
What are the common side effects of REKOOL L 20MG TABLET?
The most common side effects of taking REKOOL L 20MG TABLET are nausea, vomiting, stomach pain, diarrhea, constipation, infections, cough, sore throat, or headache. Consult your doctor if any of these symptoms worsen.
Article Information
Written By
DETAILS Written By Dr. Dhivakaran R
Medical Content Writer
Reviewed By
Dr. Sankara Babu Gorle
Medical Expert
Last Updated
02 Mar 2023