RABSULES D CAPSULE 10'S
Key Information
Generic Name
Generic Name domperidone+rabeprazole
Manufacturer
Nulife Pharmaceuticals
Variant
10 Capsule(s) in a Strip
Country of Origin
NA
Detailed Information
Introduction
INTRODUCTION ABOUT RABSULES DRABSULES D is a combination of Domperidone and Rabeprazole which belongs to the group of medicines called Dopamine Antagonists and Proton pump inhibitors respectively. RABSULES D is used to manage Gastro-Esophageal Reflux Disease (GERD) among patients who have not responded adequately to rabeprazole alone. GERD is a chronic digestive disease in which the stomach acid frequently flows into the esophagus leading to irritation of lining of food pipe. Symptoms include heartburn, chest pain, nausea, sensation of lump in throat and stomach discomfort. RABSULES D can also be used to manage peptic ulcers caused by H. pylori infection or NSAIDs use. Peptic ulcers are painful sores that develop on the linings of the stomach, esophagus or intestines. Symptoms include stomach pain, flatulence, indigestion, vomiting and fatigue. Along management with RABSULES D, try to eat less spicy foods and drink plenty of water or fluids. Avoid smoking or alcohol consumption as it may aggravate your existing condition. Patients receiving long-term management with RABSULES D should be kept on regular surveillance to rule out the risk of hypomagnesaemia (decreased magnesium levels in blood) and bone fracture, predominantly in the elderly patients and in patients with other recognized risk factors. Before taking RABSULES D inform your doctor if you have any liver, kidney or heart problems. Your doctor may reduce the dose or suggest an alternative therapy. RABSULES D is not recommended for use in pregnant or breastfeeding women and in children (aged less than 18 years). It should be used with caution in elderly patients (above 65 years of age). The most common
Uses
OF RABSULES DIt is used to manage: peptic ulcer Gastro-Esophageal Reflux Disease (GERD) (not responding to therapy with rabeprazole alone)
How It Works
RABSULES D reduces stomach ulcers and acid reflux, where Rabeprazole acts by inhibiting the secretions of stomach acid and Domperidone acts by increasing bowel movements and facilitating gastric emptying, thus leading to rapid symptom relief and healing of stomach ulcers and esophageal lesions.
Directions for Use
Take RABSULES D as advised by your physician. Swallow RABSULES D with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
Side Effects
taking RABSULES D are nausea, vomiting, stomach pain, diarrhea or constipation. Consult your doctor if any of these symptoms worsen. USES OF RABSULES DIt is used to manage: peptic ulcer Gastro-Esophageal Reflux Disease (GERD) (not responding to therapy with rabeprazole alone) HOW RABSULES D WORKSRABSULES D reduces stomach ulcers and acid reflux, where Rabeprazole acts by inhibiting the secretions of stomach acid and Domperidone acts by increasing bowel movements and facilitating gastric emptying, thus leading to rapid symptom relief and healing of stomach ulcers and esophageal lesions. DIRECTIONS FOR USETake RABSULES D as advised by your physician. Swallow RABSULES D with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition. SIDE EFFECTS OF RABSULES DCOMMON Nausea Vomiting Diarrhea Constipation stomach pain flatulence Cough, sore throat, runny nose Back pain Weakness or loss of strength Flu like symptoms Sleeplessness Headache, dizziness Infection Dry mouth Benign polyps in the stomach UNCOMMON Nervousness Sleepiness Bronchitis (inflammation of the bronchus) Sinusitis (inflammation of the sinus) Indigestion, belching in the stomach (excess air accumulation in the stomach) Muscle pain, leg pain, joint pain Fracture of hip, wrist or spine Urinary tract infection Chest pain Chills, fever Decreased libido Anxiety Itching Breast pain or tenderness Galactorrhea (milk discharge from the breast) RARE Changes in white blood cells Signs of low platelet count in blood (easy bruising or bleeding) Hypersensitivity (swelling of the face, eyelids, mouth, tongue or throat, decreases in blood pressure, difficulty in breathing) Loss of appetite Anorexia (an eating disorder) Depression Visual disturbance Gastritis (inflammation of the stomach lining) Stomatitis (sore mouth) Sweating Taste disturbance Hepatitis (inflammation of the liver caused by viral infection) Jaundice (yellowing of the skin and whites of the eyes) Hepatic encephalopathy (brain damage caused by liver infection) Bullous reactions (severe skin reactions with fluid filled blisters) Interstitial nephritis (inflammation of the kidneys) Weight gain Stop taking RABSULES D and contact your doctor immediately if you experience the following side effects: Severe allergic reaction (sudden wheezing, swelling of lips, face or body, rash, fainting or difficulties swallowing) Symptoms of liver problems (yellow skin, dark urine and tiredness) Severe skin reactions such as erythema multiforme, stevens-johnson syndrome or toxic epidermal necrolysis (reddening of skin with blisters or peeling and may be associated with a high fever and joint pains, also severe blisters and bleeding in the lips, eyes, mouth, nose and genitals) Seizures Involuntary movements of the face or arms and legs, excessive trembling, excessive muscle stiffness or muscle spasm Heart rhythm disorders (rapid or irregular heartbeat)
Warnings & Precautions
& PRECAUTIONSPREGNANCYContraindicatedRABSULES D is not recommended for use during pregnancy. Consult your doctor before taking RABSULES D. BREASTFEEDINGContraindicatedRABSULES D is not recommended for use in breast-feeding women. Consult your doctor before taking RABSULES D. DRIVING AND USING MACHINESUse with CautionDo not drive or operate any machines if you experience sleepiness, confusion or less control over your movements. Consult your doctor before taking RABSULES D. ALCOHOLConsult your doctorAvoid consumption of alcohol while taking RABSULES D, as it could aggravate your existing condition. KIDNEYContraindicatedRABSULES D is not recommended for use in patients with kidney impairment. Consult your doctor before taking RABSULES D. LIVERConsult your doctorRABSULES D is not recommended for use in patients with moderate or severe liver impairment and it should be used with caution in patients with liver problems. Consult your doctor before taking RABSULES D. ALLERGYContraindicatedDo not take RABSULES D if you are allergic to Domperidone or Rabeprazole. HEART DISEASEContraindicatedRABSULES D is not recommended for use in patients with heart problems such as prolongation of QT interval or congestive heart failure. Consult your doctor before taking RABSULES D. USE IN PEDIATRICSContraindicatedRABSULES D is not recommended for use in children and adolescents (aged less than 18 years) due to lack of safety and effectiveness. Consult your doctor for advice. USE IN GERIATRICSUse with CautionRABSULES D should be taken with caution in elderly patients (aged 65 years or above). Consult your doctor before taking RABSULES D. OTHERSRABSULES D is not recommended for use if you: Have bloody stools or bleeding in the gut Have blockage or tear in the intestines Have severe fluid or electrolyte disturbances Have prolactinoma (a non-cancerous tumor of pituitary gland) Have phenylketonuria (a metabolic disorder) Have problem that causes low levels of potassium or magnesium or high levels of potassium in the blood Have hereditary problems of galactose intolerance, total lactase deficiency or glucose-galactose malabsorption Before taking RABSULES D, inform your physician if you: Have osteoporosis Have vitamin B12 deficiency (sore tongue, mouth ulcers, pale skin, depression) Are going to test Chromogranin A level
Drug Interactions
SA. Drug-Drug interactions: Before taking RABSULES D inform to your doctor, if you are taking any of these medicines: Other medicines used to manage gastrointestinal problems (Ex. Cisapride, dolasetron, prucalopride, diphemanil) Medicines used to manage heart problems or hypertension (Ex. Digoxin, apomorphine, disopyramide, hydroquinidine, quinidine, amiodarone, dofetilide, dronedarone, ibutilide, sotalol, diltiazem or verapamil) Medicines used to manage HIV infection (Ex. Atazanavir, nelfinavir, saquinavir) Medicines used to manage hepatitis C (Ex. Telaprevir) Antipsychotics (used to manage mental illness) Ex. Haloperidol, pimozide, sertindole Antidepressants (used to manage depression) Ex. Escitalopram or citalopram Antibiotics (used to manage bacterial infections) Ex. Moxifloxacin, erythromycin, levofloxacin, clarithromycin, telithromycin or amoxicillin Medicines used to manage malaria (Ex. Halofantrine, lumefantrine) Antihistamines (used to manage allergies) Ex. Mizolastine, mequitazine Medicines used to manage cancer (Ex. Toremifene, vandetanib, vincamine, erlotinib, dasatinib, nilotinib) Methotrexate (used to manage cancer and auto-immune disease) Bepridil (used to manage hypertension) Methadone (used to relieve pain) Iron salts (used to manage iron deficiency anemia) Tacrolimus or mycophenolate mofetil (used to manage graft rejection) Ketoconazole and itraconazole (used to manage fungal infection) Pentamidine (used to manage parasite infections) Warfarin (used to manage clots) Overdosage: If you or anyone else take too much of RABSULES D, contact your doctor immediately or go to a hospital straight away. Overdosage symptoms of RABSULES D might include altered consciousness, agitation, convulsions, disorientation, sleepiness and extrapyramidal reactions (such as rigidity, tremor, drooling etc.). SYNOPSIS Drug : Domperidone, Rabeprazole Pharmacological Category : Dopamine antagonist, Proton pump inhibitor Therapeutic Indication : Peptic ulcer, GERD Dosage Forms : Tablet, Capsule MORE INFORMATIONSTORAGE Keep RABSULES D out of reach of children Store RABSULES D at room temperature
Frequently Asked Questions
Common questions and answers about RABSULES D CAPSULE 10'S.
Can RABSULES D cause diarrhea?
Yes. RABSULES D can cause diarrhea in some individuals. Keep yourself hydrated by drinking plenty of fluids, oral electrolytes and juices. Do not self-manage diarrhea if it persists for a longer period. Contact your doctor for advice.
Can RABSULES D cause acid reflux?
No. RABSULES D is used to manage Gastro-Esophageal Reflux Disease (GERD) and does not cause acid reflux. If you experience any unusual symptoms after taking RABSULES D, kindly consult your doctor.
Can RABSULES D cause kidney damage?
RABSULES D may rarely cause damage to your kidneys (Ex. interstitial nephritis). However, inform your doctor immediately if you experience any signs of kidney damage such as dark urine, blood in urine, painful urination or lower abdominal discomfort during management with RABSULES D. Your doctor might reduce the dose or suggest an alternative therapy.
When and how should I take RABSULES D?
Take RABSULES D on an empty stomach or as advised by your physician. Swallow the medicine as a whole and do not crush or chew the medicine. Your doctor will decide the correct dose of RABSULES D and duration of therapy for you, depending upon your age, body weight and health condition.
Can RABSULES D be used in children?
No. RABSULES D is not recommended for use in children and adolescents (below 18 years) due to lack of safety and effectiveness. Kindly consult child’s doctor if your child experiences any symptoms of gastro-esophageal reflux disease or peptic ulcer (such as nausea, vomiting, discomfort in upper stomach, stomach pain, heartburn, burping, etc.).
Article Information
Written By
DETAILS Written By Dr. Janet.C
Medical Content Writer
Reviewed By
Dr. Sankara Babu Gorle
Medical Expert
Last Updated
11 Jul 2024