Premarin Vaginal Cream 14Gm
Key Information
Generic Name
Generic Name Conjugated Estrogen 0.625 mg
Manufacturer
Pfizer Ltd
Country of Origin
India
Detailed Information
Introduction
INTRODUCTIONPREMARIN VAGINAL contains Conjugated estrogens which belongs to the group of medicines called Hormone Replacement Therapy. It is used to manage vaginal itching, inflammation, dryness, and vaginal thinning caused due to estrogen deficiency (atrophic vaginitis). It can also be used to manage itching and inflammation of vulva and other parts of the genital area such as labia minora, clitoris and vaginal orifice (kraurosis vulvae). It also helps in manageing moderate to severe dyspareunia (genital pain during sexual intercourse) that occurs due to menopause. Conjugated estrogen is a synthetic derivative of a female sex hormones called estrogen. It supplements our body with sufficient levels of estrogens during estrogen deficiency states. As a result, it prevents the vaginal walls and the genital area from becoming dry, thin, inflamed, or itchy and reduces genital pain. During management with PREMARIN VAGINAL, your doctor will instruct you to have periodic blood tests and regular physical examination (breast examination) to avoid the risk of unwanted
Uses
OF PREMARIN VAGINALIt is used to manage: Atrophic vaginitis (vaginal itching, inflammation, dryness, and vaginal thinning) Kraurosis vulvae (itching and inflammation of the vulva and other parts of genital area) Moderate to severe dyspareunia (genital pain during sexual intercourse)
How It Works
PREMARIN VAGINAL supplements our body with sufficient levels of a female sex hormone called estrogen. This helps in manageing problems associated with estrogen deficiency states. As a result, it prevents the vaginal walls and the genital area from becoming dry, thin, inflamed, or itchy and reduces genital pain.
Directions for Use
Apply PREMARIN VAGINAL as directed by your physician. It should be used only in and around the vagina or the genital area. PREMARIN VAGINAL comes in a tube along with an applicator. Remove the cap from the tube and connect the nozzle end of the applicator with the tube. Gently squeeze the sufficient medicine from the tube into the applicator. The marking present in the applicator may help you to measure the correct dosage as instructed by your doctor. Remove the applicator from the tube and lie down on your back or in any comfortable position that allows deep penetration into the genital area. Gently insert the applicator into the vagina. Press the plunger present in the applicator downwards to release the medicine in the vagina. Remove the applicator from the vagina after application. To cleanse the applicator, pull the plunger out
Side Effects
applying PREMARIN VAGINAL are stomach pain, back pain, breast pain or tenderness, headache, vaginal infection, or vaginal discharge. Consult your doctor if any of these side effect worsens. Also, inform your doctor if you experience any changes in your breast such as breast pain, tenderness, discharge from the nipple, or lump growth in the breasts, heavy menstrual bleeding, pain, swelling, redness of the legs, sudden chest pain or difficulty in breathing after using PREMARIN VAGINAL. USES OF PREMARIN VAGINALIt is used to manage: Atrophic vaginitis (vaginal itching, inflammation, dryness, and vaginal thinning) Kraurosis vulvae (itching and inflammation of the vulva and other parts of genital area) Moderate to severe dyspareunia (genital pain during sexual intercourse) HOW PREMARIN VAGINAL WORKSPREMARIN VAGINAL supplements our body with sufficient levels of a female sex hormone called estrogen. This helps in manageing problems associated with estrogen deficiency states. As a result, it prevents the vaginal walls and the genital area from becoming dry, thin, inflamed, or itchy and reduces genital pain. DIRECTIONS FOR USEApply PREMARIN VAGINAL as directed by your physician. It should be used only in and around the vagina or the genital area. PREMARIN VAGINAL comes in a tube along with an applicator. Remove the cap from the tube and connect the nozzle end of the applicator with the tube. Gently squeeze the sufficient medicine from the tube into the applicator. The marking present in the applicator may help you to measure the correct dosage as instructed by your doctor. Remove the applicator from the tube and lie down on your back or in any comfortable position that allows deep penetration into the genital area. Gently insert the applicator into the vagina. Press the plunger present in the applicator downwards to release the medicine in the vagina. Remove the applicator from the vagina after application. To cleanse the applicator, pull the plunger outside and wash it with mild soap and warm water. If you want to apply PREMARIN VAGINAL to the external parts of vagina, take the required quantity of PREMARIN VAGINAL and apply it at the required sites of the genital area (such as vulva, labia minora, clitoris and vaginal orifice). Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and health condition. SIDE EFFECTS OF PREMARIN VAGINALCOMMON headache breast pain irregular vaginal bleeding or spotting stomach or abdominal cramps, bloating nausea and vomiting hair loss fluid retention vaginal yeast infection vaginal burning, irritation, and itching high blood sugar levels RAREStop applying PREMARIN VAGINAL and contact your doctor immediately if you experience any of the following side effects: unexplained vaginal bleeding signs of blood clots (such as heart attack, stroke, pain, swelling and redness of the legs, sudden chest pain, difficulty in breathing) signs of liver problems (such as yellowing of the skin or whites of the eyes (jaundice)) dementia (disorder of thinking) signs of high blood pressure (such as headache, tiredness, dizziness) migraine-like headache signs of allergic reaction (such as skin rash, itching, shortness of breath, difficulty in breathing, and a swollen face) signs of breast cancer (breast pain or tenderness, swollen breasts, discharge from the nipples and changes in breast tissue) signs of uterine cancer (pelvic pain, abnormal vaginal bleeding, weight loss)
Warnings & Precautions
& PRECAUTIONSPREGNANCY[GBNKEYWORD is not recommended for use in pregnant women. Therefore, consult your doctor before using it. BREASTFEEDING[GBNKEYWORD is not recommended for use in breastfeeding women. Therefore, consult your doctor before using it. KIDNEYPREMARIN VAGINAL should be used with caution in patients with kidney problems. Therefore, consult your doctor before using it. LIVERPREMARIN VAGINAL is not recommended for use in patients with liver diseases (such as cholestatic jaundice). Therefore, consult your doctor before using it. ALLERGYDo not use PREMARIN VAGINAL if you are allergic to Conjugated Estrogens. LUNGSPREMARIN VAGINAL is not recommended for use in patients having blood clots in their lungs (pulmonary embolism). It should be used with caution in patients having asthma. Therefore, consult your doctor before using it. HEART DISEASEPREMARIN VAGINAL is not recommended for use in women with heart diseases (such as heart attack or heart block). Therefore, consult your doctor before using it. OTHERSPREMARIN VAGINAL is not recommended for use if you: have unusual vaginal bleeding have or have ever had certain cancers such as breast cancer or uterine cancer have or have ever had blood clots have been diagnosed with bleeding disorder such as hemophilia had a stroke have any upcoming surgery Before applying PREMARIN VAGINAL, inform your doctor if you: have epilepsy have diabetes have migraine are overweight have high blood cholesterol levels have endometriosis (a condition where the inner lining of the uterus grows outside the uterus) have or ever had systemic lupus erythematosus (a serious disease in which immune system attacks its own body) have thyroid problems such as goiter (enlargement of the thyroid gland) or thyroid nodules (lumps in the thyroid gland) have hypercalcemia (high calcium levels in your blood) Use in pediatrics: PREMARIN VAGINAL is not recommended for use in children and adolescents (aged below 18 years). Therefore, consult your doctor before using it. Use in geriatrics: PREMARIN VAGINAL should be used with caution in elderly women (aged 65 years or above). Therefore, consult your doctor before using it.
Drug Interactions
SA. Drug-Drug Interaction: Before applying PREMARIN VAGINAL, inform your doctor, if you are taking any of the following: medicines used to manage epilepsy (Ex. phenobarbital, phenytoin, carbamazepine) medicines used to manage tuberculosis (Ex. rifampicin, rifabutin) medicine used to manage HIV infection (Ex. nevirapine, efavirenz, ritonavir and nelfinavir) medicines used to manage bacterial infections (Ex. erythromycin, clarithromycin) medicines used to manage fungal infections (Ex. ketoconazole, itraconazole) St. john’s wort (an herbal medication used to manage depression) B. Drug-Food Interaction: Avoid drinking grapefruit juice while using PREMARIN VAGINAL since it may alter effect of this medicine. Overdosage: If you or anyone else accidentally used PREMARIN VAGINAL excessively, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose might include nausea, vomiting, breast tenderness, abdominal pain, drowsiness and fatigue, and withdrawal bleeding. SYNOPSIS Drug : Conjugated Estrogen Pharmacological Category : Synthetic Estrogen derivative Therapeutic Indication : Atrophic Vaginitis, Kraurosis Vulvae, Dyspareunia Dosage Forms : Tablet, Cream MORE INFORMATION Keep PREMARIN VAGINAL out of reach of children Store PREMARIN VAGINAL at room temperature