PRE Aldonil 150mg Tablet 10'S
Key Information
Generic Name
Generic Name Epalrestat 150 mg+Pregabalin 150 mg
Manufacturer
Zydus Healthcare Ltd
Variant
10 Tablet(s) in a Strip
Country of Origin
India
Detailed Information
Introduction
PRE ALDONIL 150MG TABLET is a combination of Epalrestat and Pregabalin which belongs to the group of medicines called Aldose reductase inhibitors and Cyclic GABA analogues respectively. It is used in the management of diabetic neuropathy (nerve pain). Diabetic neuropathy is a nerve damage occurring over time because of high sugar and fat levels in the blood due to diabetes. Symptoms depend on the type of neuropathy, such as pain and numbness in your feet or problems with the organ functions like that of your heart and bladder. During management with PRE ALDONIL 150MG TABLET, your doctor will closely monitor if you have diabetic peripheral neuropathy with irreversible organic changes. Before taking PRE ALDONIL 150MG TABLET, inform your doctor if you have a history of heart, liver or kidney disease, alcoholism or any drug abuse or dependence. PRE ALDONIL 150MG TABLET should not be used in pregnant and breastfeeding women unless con
Uses
OF PRE ALDONIL 150MG TABLET Manage diabetic nerve pain
How It Works
PRE ALDONIL 150MG TABLET reduces pain where epalrestat inhibits an enzyme (aldose reductase) which converts glucose into sorbitol. In diabetics, there is excess sorbitol production that gets deposited in nerves and other tissues, causing diabetic neuropathy. Thus, epalrestat delays sorbitol accumulation in nerves and other tissues to delay progression of diabetic neuropathy, and pregabalin provides neuroprotection, thus managing neuronal injury or damage.
Directions for Use
Take PRE ALDONIL 150MG TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration of PRE ALDONIL 150MG TABLET for you according to your age, body weight and disease condition.
Side Effects
taking PRE ALDONIL 150MG TABLET are feeling generally unwell, headache, stomach pain, nausea, dizziness, dry mouth and constipation. Contact your doctor if any of the symptoms worsen. USES OF PRE ALDONIL 150MG TABLET Manage diabetic nerve pain HOW PRE ALDONIL 150MG TABLET WORKSPRE ALDONIL 150MG TABLET reduces pain where epalrestat inhibits an enzyme (aldose reductase) which converts glucose into sorbitol. In diabetics, there is excess sorbitol production that gets deposited in nerves and other tissues, causing diabetic neuropathy. Thus, epalrestat delays sorbitol accumulation in nerves and other tissues to delay progression of diabetic neuropathy, and pregabalin provides neuroprotection, thus managing neuronal injury or damage. DIRECTIONS FOR USETake PRE ALDONIL 150MG TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration of PRE ALDONIL 150MG TABLET for you according to your age, body weight and disease condition. SIDE EFFECTS OF PRE ALDONIL 150MG TABLETCOMMON feeling generally unwell dizziness, drowsiness, headache increased appetite feeling elated, confused, disorientated, low sexual interest, irritability disturbance in attention, clumsiness, memory impairment or loss, shaking, trouble speaking, tingling, numbness, sleepiness, lethargy, sleep problems, tiredness, feeling abnormal blurred or double vision spinning sensation, problems with balance dry mouth, constipation, vomiting, gas, diarrhoea, nausea, swollen abdomen, stomach pain difficulties with erection swollen body including extremities unusual walking style weight gain muscle cramp, joint, back or limb pain sore throat UNCOMMON loss of appetite, weight loss unusual eye movement, changes in eyesight including tunnel vision, flashes of light, jerky movements, reduced reflexes, increased activity, dizziness on standing, sensitive skin, loss of taste, burning sensation, shaking on movement, decreased consciousness, increased sensitivity to noise, feeling unwell dryness, swelling, pain, weakness, watering, irritation of eye heart rhythm disturbances, increased heart rate, heart failure flushing, hot flushes trouble breathing, dry nose, nasal congestion increased salivation, heartburn, numbness around mouth sweating, rash, chills, fever muscle twitching, stiffness or pain, joint swelling, neck pain breast pain trouble or painful urination, retention weakness, thirst, chest tightness itchiness, hives, runny nose, nosebleed, cough, snoring painful periods cold hands and feet RARE abnormal sense of smell, swinging vision, changed perception of depth, visual brightness dilated pupils, cross eyes cold sweat, throat tightness, swollen tongue inflammation of the pancreas trouble swallowing slow or decreased body movement trouble writing properly raised fluid in the abdomen, fluid in the lungs muscle damage breast discharge, abnormal breast growth, breast enlargement in males interrupted periods inappropriate behaviour inflammation of the eyes jaundice (yellow skin and eyes) Stop taking PRE ALDONIL 150MG TABLET and contact your doctor immediately if you experience any of the following side effects: swollen face or tongue, skin turning red and starting to blister or peel allergic reaction (swollen face, lips, tongue, and throat, diffuse skin rash) serious skin rashes like Stevens-Johnson syndrome, toxic epidermal necrolysis (reddish non-elevated, target-like or circular patches on the trunk, often with central blisters, skin peeling, ulcers of mouth, throat, nose, genitals and eyes, fever and flu-like symptoms) loss of vision, other changes in eyesight kidney failure, reduced urine volume thoughts of harming or killing self fits difficulty breathing or shallow breaths
Warnings & Precautions
& PRECAUTIONSPREGNANCYPRE ALDONIL 150MG TABLET should not be used in pregnant women unless considered necessary by your doctor. Consult your doctor before taking it. BREASTFEEDINGPRE ALDONIL 150MG TABLET should not be used in breastfeeding women unless considered necessary by your doctor. Consult your doctor before taking it. DRIVING AND USING MACHINESDo not drive or operate any machines if you experience dizziness, sleepiness or decreased concentration after taking PRE ALDONIL 150MG TABLET. ALCOHOLAvoid consumption of alcohol while taking PRE ALDONIL 150MG TABLET. It should be used with caution in patients with a history of alcoholism. Consult your doctor before taking it. KIDNEYPRE ALDONIL 150MG TABLET should be used with caution in patients with kidney disease or impairment. Consult your doctor before taking PRE ALDONIL 150MG TABLET. LIVERPRE ALDONIL 150MG TABLET should be used with caution in patients with liver disease. Consult your doctor before taking PRE ALDONIL 150MG TABLET. ALLERGYDo not take PRE ALDONIL 150MG TABLET if you are allergic to Epalrestat, Pregabalin or any other ingredients of this medicine. LUNGSPRE ALDONIL 150MG TABLET should be used with caution in patients with respiratory disorders. Consult your doctor before taking PRE ALDONIL 150MG TABLET. HEART DISEASEPRE ALDONIL 150MG TABLET should be used with caution in patients with a history of heart disease. Consult your doctor before taking PRE ALDONIL 150MG TABLET. OTHERSBefore taking PRE ALDONIL 150MG TABLET, inform your doctor if you: have a history of any drug abuse or dependence have nervous system disorders have diabetic peripheral neuropathy Use in pediatrics: PRE ALDONIL 150MG TABLET is not recommended for use in children and adolescents (aged below 18 years) due to lack of safety and effectiveness. Consult your child’s doctor for advice. Use in geriatrics: PRE ALDONIL 150MG TABLET should be used with caution in elderly patients (aged 65 years and above) especially with kidney or heart problems. Consult your doctor before taking it.
Drug Interactions
SA. Drug - Drug interactions: Before taking PRE ALDONIL 150MG TABLET, inform your doctor if you are taking any of the following medicines: medicines used to manage severe pain (Ex. morphine, fentanyl) oxycodone (used to relieve pain) lorazepam (used to manage anxiety) Overdosage: If you or anyone else accidentally take too much of PRE ALDONIL 150MG TABLET, consult your doctor immediately or visit the nearby hospital. Overdosage symptoms of PRE ALDONIL 150MG TABLET includes sleepiness, confusion, agitation or restlessness. SYNOPSIS Drug : Epalrestat, Pregabalin Pharmacological Category : Aldose reductase inhibitor, Cyclic GABA analogue Therapeutic Indication : Diabetic neuropathy Dosage Forms : Tablet MORE INFORMATION Keep PRE ALDONIL 150MG TABLET out of reach of children Store PRE ALDONIL 150MG TABLET at room temperature
Article Information
Written By
DETAILS Written By Dr. R. Dinesh John Rajkumar
Medical Content Writer
Reviewed By
Dr. Sankara Babu Gorle
Medical Expert
Last Updated
13 Dec 2022