Pletoz 100mg Tablet 10'S
Key Information
Generic Name
Generic Name Cilostazol 100 mg
Manufacturer
Cipla Ltd
Variant
10 Tablet(s) in a Strip
Country of Origin
India
Detailed Information
Introduction
PLETOZ 100MG TABLET contains Cilostazol which belongs to the group of medicines called Phosphodiesterase type 3 inhibitors. It is used in the management of intermittent claudication, which is defined as the cramp-like pain in the legs while walking caused by insufficient blood supply in the legs. Symptoms include pain, ache, discomfort or fatigue in muscles every time, when those muscles are used (usually the calves, thighs, buttocks, hips or feet). Along with this management your doctor might advise you to make lifestyle modifications like increasing regular exercise and stop smoking. Prior to the management, your doctor may want you to take ankle-brachial index test to understand your existing condition. PLETOZ 100MG TABLET is not recommended for use in patients having severe heart problems (such as heart failure, heart attack), uncontrolled blood pressure, kidney or liver disease, active stomach ulcer and stroke. Do not drink large amounts of grapefruit juice while taking PLETOZ 100MG TABLET as it may reduce the effect of this medicine. PLETOZ 100MG TABLET is not recommended for use among pregnant or breastfeeding women, therefore consult your doctor before taking it. This medicine is not recommended for use in children and adolescents. The most common
Uses
OF PLETOZ 100MG TABLET Manage intermittent claudication
How It Works
PLETOZ 100MG TABLET acts by inhibiting the activity of certain enzymes (phosphodiesterase) which helps in the increase in the level of cAMP (cellular messengers to initiate certain actions) in platelets and blood vessels. The cAMP helps in widening of some blood vessels and reducing the clotting activity of platelets in
Directions for Use
Take PLETOZ 100MG TABLET as advised by your physician. Swallow PLETOZ 100MG TABLET with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
Side Effects
taking PLETOZ 100MG TABLET are headache, abnormal stools, diarrhea, abdominal discomfort, dizziness, nausea and loss of appetite. Consult your doctor if any of the side effects worsen over the time. USES OF PLETOZ 100MG TABLET Manage intermittent claudication HOW PLETOZ 100MG TABLET WORKSPLETOZ 100MG TABLET acts by inhibiting the activity of certain enzymes (phosphodiesterase) which helps in the increase in the level of cAMP (cellular messengers to initiate certain actions) in platelets and blood vessels. The cAMP helps in widening of some blood vessels and reducing the clotting activity of platelets inside the blood vessels. Hence increasing the blood circulation to the legs making it easier and less painful to walk. DIRECTIONS FOR USETake PLETOZ 100MG TABLET as advised by your physician. Swallow PLETOZ 100MG TABLET with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition. SIDE EFFECTS OF PLETOZ 100MG TABLETCOMMON headache, dizziness abnormal stools, diarrhea heart pounding runny nose abdominal pain, abdominal discomfort (indigestion), excessive burping nausea or vomiting, general weakness loss of appetite swelling of the ankles, feet or face skin allergy (rash or changes in appearance of the skin, itchy skin, patchy bleeding in the skin) UNCOMMON shortness of breath, cough, chills unexpected bleeding, tendency to bleed (Ex. nose bleeding and blood in spit or urine) fainting, anxiety difficulty sleeping, unusual dreams allergic reaction, aches and pains stomachache (gastritis) RARE problems with the kidneys Stop taking PLETOZ 100MG TABLET and contact your doctor immediately if you experience any of the following side effects: easy bruising and bleeding, fever or sore throat a pain or uncomfortable feeling in the chest, often spreading to the arms or neck and sometimes to the shoulders and back which may be caused by too little blood and oxygen supplying to the heart heart attack, irregular heartbeat, increased heart rate heart problems causing shortness of breath or ankle swelling increased blood sugar levels bleeding of the stomach and eyes pneumonia kidney failure
Warnings & Precautions
& PRECAUTIONSPREGNANCYContraindicatedPLETOZ 100MG TABLET is not recommended for use in pregnant women. Consult your doctor before taking PLETOZ 100MG TABLET. BREASTFEEDINGContraindicatedPLETOZ 100MG TABLET is not recommended for use in breastfeeding women. Consult your doctor before taking PLETOZ 100MG TABLET. DRIVING AND USING MACHINESUse with CautionDo not drive or operate heavy machines if you experience dizziness while taking PLETOZ 100MG TABLET. KIDNEYContraindicatedPLETOZ 100MG TABLET is not recommended for use in patients with severe kidney disease. Consult your doctor before taking PLETOZ 100MG TABLET. LIVERContraindicatedPLETOZ 100MG TABLET is not recommended for use in patients with moderate or severe liver disease. Consult your doctor before taking PLETOZ 100MG TABLET. ALLERGYContraindicatedDo not take PLETOZ 100MG TABLET if you are allergic to Cilostazol or any other ingredients of this medicine. HEART DISEASEConsult your doctorPLETOZ 100MG TABLET is not recommended for use in patients with heart failure, had heart attack, persistent chest pain at rest, any heart surgery in the last 6 months, suffered from blackouts due to heart disease or any severe disturbances of the heartbeat. It should be taken with caution in patients with severe heart problem or any other problems with your heart beat and high blood pressure. Consult your doctor before taking PLETOZ 100MG TABLET. OTHERSPLETOZ 100MG TABLET is not recommended for use if you: have any condition which increases the risk of bleeding or bruising, such as active stomach ulcers, stroke in the past six months, eye problems with diabetes and uncontrolled blood pressure Before taking PLETOZ 100MG TABLET, inform your doctor if you: need to have surgery (including teeth removal) Use in pediatrics: PLETOZ 100MG TABLET is not recommended for use in children and adolescents. Consult your child’s doctor for advice. Use in geriatrics: PLETOZ 100MG TABLET should be taken with caution in elderly patients. Consult your doctor before taking PLETOZ 100MG TABLET.
Drug Interactions
SA. Drug-Drug interactions: Before taking PLETOZ 100MG TABLET, inform your doctor if you are taking any of the following medicines: acetylsalicylic acid (aspirin) (used to manage painful inflammatory condition of muscle or joints) anticoagulant medicines (Ex. heparin, warfarin, clopidogrel, dabigatran, rivaroxaban, apixaban) (used to manage or manage blood clots) certain antibiotics Ex. erythromycin, clarithromycin or rifampicin (used to manage bacterial infections) ketoconazole (used to manage fungal infections) omeprazole (used to manage acidity in the stomach) diltiazem (used to manage high blood pressure or chest pain) cisapride (used to manage stomach disorders) medicines used to manage high cholesterol in the blood (Ex. lovastatin, simvastatin) halofantrine (used to manage malaria) protease inhibitors such as atazanavir, darunavir (used to manage HIV infection) pimozide (used to manage mental illnesses) ergot derivatives Ex. ergotamine, dihydroergotamine (used to manage or manage migraine headaches) st. john’s wort (herbal remedy), carbamazepine or phenytoin (used to manage convulsions) diuretics Ex. hydrochlorothiazide, furosemide (used to manage fluid retention) calcium channel blockers such as verapamil, amlodipine, angiotensin-converting-enzyme inhibitors such as captopril, lisinopril, angiotensin II receptor blockers such as valsartan, candesartan and beta blockers such as labetalol, carvedilol (used to manage high blood pressure) B. Drug-Food interactions: Do not drink large amounts of grapefruit juice while taking PLETOZ 100MG TABLET as it may reduce the effect of this medicine and do not take together with meals as it may affects its absorption and increase the risk of side effects. Overdosage: If you or anyone else accidentally take too much of PLETOZ 100MG TABLET, consult your doctor immediately or visit the nearby hospital. Overdosage symptoms of PLETOZ 100MG TABLET includes severe headache, diarrhea, increase in heart rate and irregularities of the heartbeat. SYNOPSIS Drug : Cilostazol Pharmacological Category : Platelet aggregation inhibitors Therapeutic Indication : Intermittent claudication Dosage Forms : Tablet MORE INFORMATION Keep PLETOZ 100MG TABLET out of reach of children Store PLETOZ 100MG TABLET at room temperature
Frequently Asked Questions
Common questions and answers about Pletoz 100mg Tablet 10'S.
How does PLETOZ 100MG TABLET work?
PLETOZ 100MG TABLET acts by inhibiting the activity of certain enzymes (phosphodiesterase) which helps in the increase in the level of cAMP (cellular messengers to initiate certain actions) in platelets and blood vessels. The cAMP helps in widening of some blood vessels and reducing the clotting activity of platelets inside the blood vessels. Hence increasing the blood circulation to the legs making it easier and less painful to walk.
What is PLETOZ 100MG TABLET used for?
PLETOZ 100MG TABLET is used in the management of intermittent claudication, which is defined as the cramp-like pain in the legs while walking caused by insufficient blood supply in the legs. Symptoms include pain, ache, discomfort or fatigue in muscles every time, when those muscles are used (usually the calves, thighs, buttocks, hips or feet).
Can I stop taking PLETOZ 100MG TABLET on my own?
If you stop taking PLETOZ 100MG TABLET the pain in your legs may come back or get worse. Therefore, you should only stop taking it if you notice side effects requiring urgent medical attention or if your doctor tells you to.
What to do If I forget to take a dose of PLETOZ 100MG TABLET?
You should take PLETOZ 100MG TABLET immediately when you remember. If it is time for the next dose skip the missed dose and follow the regular dose schedule. Do not double the dose to match up the missed dose.
Can PLETOZ 100MG TABLET be used in pregnant or breast-feeding women?
PLETOZ 100MG TABLET is not recommended for use in pregnant and breast-feeding women. Consult your doctor before taking this medicine if you are pregnant, planning to become pregnant or breast-feeding your child.
Article Information
Written By
s'%20conclusions%3A%20Cilostazol%20has%20been,higher%20odds%20of%20experiencing%20headache. 4. Adamed Pharma S.A. Electronic Medicines Compendium (EMC). [Revised in February 2020] [Accessed on 3rd May 2022] https://www.medicines.org.uk/emc/files/pil.2590.pdf USEFUL DIAGNOSTIC TESTS Ankle-brachial index test AUTHOR DETAILS Written By Dr. R. Dinesh John Rajkumar
Medical Content Writer
Reviewed By
Dr. Sankara Babu Gorle
Medical Expert
Last Updated
27 Jan 2023