Pevesca Plus SR 75mg Tablet 10'S

Neuropathic Pain (649)Rx required

Key Information

Generic Name

Generic Name Folic Acid 5 mg+Methylcobalamin 1500 mcg+Pregabalin 75 mg+Pyridoxine 20 mg

Manufacturer

Usv Private Ltd

Variant

10 Tablet(s) in a Strip

Country of Origin

India

Detailed Information

Introduction

PEVESCA PLUS SR 75MG TABLET is a combination of Folic Acid, Mecobalamin (Methylcobalamin), Pyridoxine, and Pregabalin which belongs to the group of medicines called Group B vitamins and Anticonvulsants respectively. It is used in adults to manage painful diabetic neuropathy. Diabetic neuropathy is a condition that occurs due to high blood sugar levels in which nerves get weakened and damaged throughout the body, but more often in the legs and feet. It is characterized by symptoms such as tingling sensations, numbness, pain, weakness, cramps, and extreme sensitivity to touch in the affected area. Do not take PEVESCA PLUS SR 75MG TABLET if you are allergic to folic acid, mecobalamin (methylcobalamin), pyridoxine, or pregabalin. Before taking this medicine, inform your doctor if you are suffering from a hepatic impairment, kidney impairment, congestive heart failure, or pre-existing ocular conditions (eye problems). PEVESCA PLUS SR 75MG TABLET is also not recommended for use in pregnant and breastfeeding women. It should be used with caution in children (aged 12 years or below) and elderly patients (aged 75 years or above). Consult your doctor before taking it. The common

Uses

OF PEVESCA PLUS SR 75MG TABLET Manage painful diabetic neuropathy

How It Works

PEVESCA PLUS SR 75MG TABLET helps in managing nerve health, where pregabalin lowers the abnormal nerve conduction and pain conduction in the brain and spinal cord, thereby lowering the sensation of pain. Folic acid and pyridoxine play a vital role in the growth, differentiation, and regeneration of nerves and the central nervous system, whereas methylcobalamin helps in the synthesis of a compound called myelin that covers and protects nerve fibers, thereby reversing nerve damage and lowering nerve pain.

Directions for Use

Take PEVESCA PLUS SR 75MG TABLET as advised by your physician. Swallow the medicine with a glass of water, with or without food. Do not crush or chew the medicine. Your doctor will determine the correct dose and duration for you depending upon your age, body weight, and disease condition.

Side Effects

PEVESCA PLUS SR 75MG TABLET are dizziness, sleepiness, ataxia (clumsy body movement), confusion, excessive weakness, abnormal thinking, and blurred vision. Contact your doctor or a nearby hospital if any of the conditions worsen. USES OF PEVESCA PLUS SR 75MG TABLET Manage painful diabetic neuropathy HOW PEVESCA PLUS SR 75MG TABLET WORKSPEVESCA PLUS SR 75MG TABLET helps in managing nerve health, where pregabalin lowers the abnormal nerve conduction and pain conduction in the brain and spinal cord, thereby lowering the sensation of pain. Folic acid and pyridoxine play a vital role in the growth, differentiation, and regeneration of nerves and the central nervous system, whereas methylcobalamin helps in the synthesis of a compound called myelin that covers and protects nerve fibers, thereby reversing nerve damage and lowering nerve pain. DIRECTIONS FOR USETake PEVESCA PLUS SR 75MG TABLET as advised by your physician. Swallow the medicine with a glass of water, with or without food. Do not crush or chew the medicine. Your doctor will determine the correct dose and duration for you depending upon your age, body weight, and disease condition. SIDE EFFECTS OF PEVESCA PLUS SR 75MG TABLETCOMMON dizziness sleepiness ataxia (clumsy body movement) confusion excessive weakness abnormal thinking abnormal blurred vision lack of coordination peripheral oedema (swelling due to water retention) dry mouth abdominal pain signs of an allergic reaction such as rashes, itching, shortness of breath, and noisy breathing fever increase in weight gastroenteritis (inflammation of the stomach and intestines) increased appetite vomiting nausea constipation diarrhoea flatulence abdominal distension (bloating and swelling in the stomach) ecchymosis (skin discolouration due to underlying bleeding) joint pain leg cramps muscle pain muscle weakness back pain pain in the limb cervical spasm anxiety depersonalisation stiffness and immobility of muscles decreased sense of touch or pain loss of libido uncontrolled eye movements tingling and prickling sensations sedation state of being nearly unconscious twitching tremor difficulty in speaking loss of memory memory impairment disturbance in attention lethargy extreme happiness confusion irritability disorientation sleeplessness balance disorder itching conjunctivitis (inflammation of the eye tissue) diplopia (double vision) otitis media (a middle ear infection) ringing sensation in the ears anorgasmia (impaired orgasms) impotence increased urinary frequency urinary incontinence nasopharyngitis (inflammation of the nose and throat) falls feeling drunk feeling abnormal UNCOMMON abscess (accumulation of pus) cellulitis (a bacterial infection) chills malaise (a feeling of discomfort) neck rigidity pelvic pain increased sensitivity to light inflammation of deep blood vessels congestive heart failure (impairment of the heart's ability to pump enough blood) low blood pressure postural hypotension (dip in blood pressure on changing the posture) retinal vascular disorder (disease of the eye’s blood vessels) transient loss of consciousness pounding heart rate first-degree atrioventricular block (heart block) sinus bradycardia (slow heart rhythm) cholecystitis (inflammation of the gall bladder) cholelithiasis (stones in the gallbladder) colitis (inflammation of the intestine) dysphagia (difficulty swallowing) oesophagitis (inflammation of the oesophagus) gastritis (inflammation of the stomach) gut bleeding melaena (dark stools) ulcers in the mouth pancreatitis (inflammation of the pancreas) rectal haemorrhage tongue swelling gastro-oesophageal reflux disease (disease-causing repeated flow back of acid) overproduction of saliva loss of sensation in the mouth anaemia (decreased blood cell count) eosinophilia (an increase in the count of a type of white blood cells) hypochromic anaemia (decreased amount of haemoglobin) leucocytosis (increased white blood cell count) leukopenia (decreased white blood cell count) lymphadenopathy (enlarged lymph nodes) thrombocytopenia (decreased platelet count) neutropenia (decreased white blood cell count) anorexia (an eating disorder causing weight loss or weight gain) reduced blood glucose levels arthrosis (wearing of joints) joint swelling neck pain muscle stiffness abnormal dreams agitation apathy (lack of interest) aphasia (impaired ability to communicate) circumoral paraesthesia (reduced sensations around the mouth) dysarthria (a brain disorder causing difficulty speaking) hallucinations hostility hyperalgesia (increased ability to feel pain) hyperkinesia (excessive restlessness) hypokinesia (diminished motor strength) hypotonia (decreased muscle tone) increased libido abnormal muscle jerks neuralgia (pain in the nerves) loss of consciousness psychomotor hyperactivity (excess anxiety) postural dizziness intention tremor cognitive disorder (disorder causing confusion) mental impairment speech disorder hyporeflexia (decreased reflex responses) burning sensation loss of taste function panic attack restlessness depression elevated mood mood swings word-finding difficulty dyskinesia (abnormal body movements) shortness of breath nose bleeding cough nasal congestion swelling inside the nose snoring nasal dryness loss of hair excessive sweating dry skin eczema (inflamed and itchy rashes) hirsutism (hair growth in a male pattern on the female body) skin ulcers urticaria (allergic reactions causing itchy welts) vesiculobullous rash (rashes with fluid-filled cavities) itching abnormality of accommodation or vision blepharitis (inflammation of the eyelids) peripheral vision loss reduced visual accuracy eye pain asthenopia (strain in the eyes) photopsia (visuals of light) increased lacrimation irritation in the eyes dry eyes eye haemorrhage eye swelling visual field defect hyperacusis (increased sensitivity to sounds) photophobia (discomfort with bright lights) retinal swelling abnormal ejaculation albuminuria (presence of albumin in the urine) amenorrhoea (absence of menstruation) dysmenorrhoea (painful periods) dysuria (painful urination) haematuria (blood in the urine) kidney stones leucorrhoea (abnormal discharge from the vagina) menorrhagia (heavy bleeding) metrorrhagia (abnormal bleeding between periods) nephritis (inflammation of the kidney tissues) oliguria (decreased urine volume) urinary retention urine abnormality breast pain high blood pressure hot flushes flushing cold hands and feet generalized swelling due to water retention swelling in the face due to water retention chest tightness pain very high fever thirst RARE signs of an anaphylactic reaction such as shortness of breath, chest tightness, and wheezing ascites (abnormal retention of fluid in the abdomen) granuloma (small areas of inflammation) hangover effect intentional injury retroperitoneal fibrosis (an extensive scar in the back of the abdominal cavity) shock (sudden drop in blood pressure) heart problems such as st depression, ventricular fibrillation, qt prolongation, and sinus arrhythmia painful swelling in the mouth ulcer in the food pipe pus formation near the tooth sockets myelofibrosis (bone marrow cancer) polycythaemia (increased blood haemoglobin levels) decreased prothrombin levels purpura (pinpoint bleeding below the skin) thrombocythemia (unusual bleeding) decreased glucose tolerance levels urate crystalluria (deposition of uric acid in soft tissue) chondrodystrophy (abnormal cartilage development) generalised spasm rhabdomyolysis (breakdown of muscle tissue) addiction cerebellar syndrome (a brain disorder) cogwheel rigidity (muscle rigidity causing repeated jerks) coma (complete loss of consciousness) delirium (disturbed mental abilities) delusions (false beliefs) dysautonomia (loss of nervous system function) abnormal muscle contractions involuntary muscle contractions encephalopathy (a brain disease) extrapyramidal syndrome (brain disorder causing abnormal body movements) guillain-barré syndrome (a condition in which the immune system damages healthy nerves) hypoalgesia (decreased ability to feel pain) intracranial hypertension (increased blood pressure in the brain) manic reaction (extreme mood changes) paranoid reaction (irrational thoughts) torticollis (abnormal head twisting) trismus (decreased mouth opening) convulsions parosmia (abnormal sensation of smell) dysgraphia (loss of ability to write) disinhibition (lack of restraint) peripheral neuritis (nerve damage outside the brain and spinal cord) personality disorder schizophrenic reaction (a mental disorder) atelectasis (loss of a lung lobe) bronchiolitis (inflammation of the lung tissue) hiccup laryngismus (abnormal spasms in the throat) lung swelling lung fibrosis (scarring of lung tissue) yawn water retention in lung tissue throat tightness signs of angioedema (a serious allergic reaction) such as swelling of the face exfoliative dermatitis (inflammation and peeling of the skin) lichenoid dermatitis (a type of skin swelling) melanosis (increased skin pigmentation) nail disorders petechial rash (rashes with purple-red spots) purpuric rash (rashes with dark skin patches) pustular rash (rashes with pus formation) skin atrophy (decreased skin thickness) skin necrosis (death of skin cells due to a lack of oxygen supply) formation of skin nodules signs of stevens-johnson syndrome (a serious allergic reaction) such as blistering and peeling of skin subcutaneous nodule (nodule formation below the skin) anisocoria (unequal pupil size) blindness corneal ulcer exophthalmos (protrusion of eyeballs) extraocular palsy (paralysis of an eye muscle) iritis (inflammation of an eye tissue) keratitis (inflammation of an eye tissue) oscillopsia (illusions) altered visual depth perception strabismus (an aligning disorder in the eyes) visual brightness keratoconjunctivitis (inflammation of an eye tissue) miosis (excessive contraction of the pupils of the eye) mydriasis (over-dilatation of the pupils of the eye) night blindness ophthalmoplegia (weakening of eye muscles) optic atrophy (a disorder of the optic nerve) papilloedema (swelling of an eye tissue) ptosis (drooping of the upper eyelid) uveitis (inflammation of an eye tissue) acute kidney failure, balanitis cancer of the bladder inflammation of the cervix dyspareunia (genital pain) epididymitis (inflammation of the male genital area) female lactation glomerulitis (inflammation of kidney tissue) ovarian disorder pyelonephritis (inflammation of kidney tissue) breast discharge breast enlargement breast enlargement in males Stop taking PEVESCA PLUS SR 75MG TABLET and contact your doctor if you experience any of the following side effects: signs of anaphylactoid reaction such as shortness of breath, chest tightness, and wheezing signs of angioedema (a serious allergic reaction) such as swelling of the face signs of allergic reactions such as skin redness, blisters, hives, rash, shortness of breath, and wheezing diseases of muscles markedly elevated creatine kinase levels in the blood

Warnings & Precautions

& PRECAUTIONSPREGNANCYMonitoring requiredPEVESCA PLUS SR 75MG TABLET is not recommended to be used in pregnant women unless considered necessary. Consult your doctor before taking it. BREASTFEEDINGContraindicatedPEVESCA PLUS SR 75MG TABLET is not recommended to be used in breastfeeding women. Either breastfeeding should be discontinued or this medicine. Consult your doctor before taking it. DRIVING AND USING MACHINESUse with CautionDo not drive or operate any machine if you feel dizziness and sleepiness after taking PEVESCA PLUS SR 75MG TABLET. ALCOHOLConsult your doctorAvoid regular consumption of alcohol while taking PEVESCA PLUS SR 75MG TABLET. Consult your doctor before taking it. KIDNEYUse with CautionPEVESCA PLUS SR 75MG TABLET should be used with caution in patients with renal impairment. Consult your doctor before taking it. LIVERUse with CautionPEVESCA PLUS SR 75MG TABLET should be used with caution in patients with hepatic impairment. Consult your doctor before taking it. ALLERGYContraindicatedDo not take PEVESCA PLUS SR 75MG TABLET if you are allergic to any of the ingredients of this medicine. Consult your doctor before taking it. HEART DISEASEUse with CautionPEVESCA PLUS SR 75MG TABLET should be used with caution in patients with congestive heart failure. Consult your doctor before taking it. USE IN PEDIATRICSUse with CautionPEVESCA PLUS SR 75MG TABLET should be used with caution in children (aged 12 years or below). Consult your doctor before taking it. USE IN GERIATRICSUse with CautionPEVESCA PLUS SR 75MG TABLET should be used with caution in elderly patients (aged 75 years or above). Consult your doctor before taking it. OTHERSBefore taking PEVESCA PLUS SR 75MG TABLET, inform your doctor if you: have pre-existing ocular conditions (eye problems)

Drug Interactions

SA. Drug-Drug Interactions: Before taking PEVESCA PLUS SR 75MG TABLET, inform your doctor, if you are taking any of the following medicine: gabapentin (a medicine used to manage seizures) oral contraceptives (medicines used to manage conception) Ex. oestrogen preparations lorazepam (a medicine used to manage anxiety) oxycodone (a medicine used to manage pain and inflammation) anti-epileptic drugs (medicines used to manage epilepsy) Ex. phenytoin, phenobarbital, topiramate, carbamazepine, carbamazepine, epoxide, valproic acid, lamotrigine antidiabetic agents (medicines used to manage diabetes) Ex. glyburide, insulin, metformin furosemide (a medicine used to lower blood pressure) Overdosage: If you or anyone else accidentally takes too much of PEVESCA PLUS SR 75MG TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdosage dizziness and sleepiness. SYNOPSIS Drug : Folic Acid, Mecobalamin (Methylcobalamin), Pyridoxine, and Pregabalin Pharmacological Category : Group B vitamins and Anticonvulsants Therapeutic Indication : Painful diabetic neuropathy Dosage Forms : Tablet MORE INFORMATION Keep the medicine out of reach of children Store PEVESCA PLUS SR 75MG TABLET below 30°C

Frequently Asked Questions

Common questions and answers about Pevesca Plus SR 75mg Tablet 10'S.

Q

What is PEVESCA PLUS SR 75MG TABLET used for?

A

PEVESCA PLUS SR 75MG TABLET is used in adults to manage painful diabetic neuropathy, which is a condition that occurs due to high blood sugar levels in which nerves get weakened and damaged throughout the body but more often in the legs and feet. It is characterized by symptoms such as tingling sensations, numbness, pain, weakness, cramps, and extreme sensitivity to touch in the affected area.

Q

What side effects are seen with PEVESCA PLUS SR 75MG TABLET?

A

The common side effects associated with the use of PEVESCA PLUS SR 75MG TABLET are dizziness, sleepiness, ataxia (clumsy body movement), confusion, excessive weakness, abnormal thinking, and blurred vision. Contact your doctor or a nearby hospital if any of the conditions worsen.

Q

What happens if you take more PEVESCA PLUS SR 75MG TABLET than your required dose?

A

If you or anyone else accidentally takes too much PEVESCA PLUS SR 75MG TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdosage include dizziness and sleepiness.

Q

Who should avoid taking PEVESCA PLUS SR 75MG TABLET?

A

Do not take PEVESCA PLUS SR 75MG TABLET if you are allergic to folic acid, mecobalamin (methylcobalamin), pyridoxine, or pregabalin. It is also not recommended for use in pregnant or breastfeeding women to ensure the safety of the mother and baby. Consult your doctor before taking PEVESCA PLUS SR 75MG TABLET.

Q

Is PEVESCA PLUS SR 75MG TABLET safe to use in children or elderly patients?

A

PEVESCA PLUS SR 75MG TABLET should be used with caution in children (aged 12 years or below) and elderly patients (aged 75 years or above). Consult your doctor before taking PEVESCA PLUS SR 75MG TABLET.

Q

How does PEVESCA PLUS SR 75MG TABLET work?

A

PEVESCA PLUS SR 75MG TABLET helps in managing nerve health, where pregabalin lowers the abnormal nerve conduction and pain conduction in the brain and spinal cord, thereby lowering the sensation of pain. Folic acid and pyridoxine play a vital role in the growth, differentiation, and regeneration of nerves and the central nervous system, whereas methylcobalamin helps in the synthesis of a compound called myelin that covers and protects nerve fibers, thereby reversing nerve damage and lowering nerve pain.

Q

What is the method of taking PEVESCA PLUS SR 75MG TABLET?

A

Take PEVESCA PLUS SR 75MG TABLET as advised by your physician. Swallow the medicine with a glass of water, along with or without food. Do not crush or chew the medicine. Your doctor will determine the correct dose and duration for you depending upon your age, body weight, and disease condition.

Q

Is PEVESCA PLUS SR 75MG TABLET safe for pregnant women to use?

A

According to animal studies, PEVESCA PLUS SR 75MG TABLET is not recommended for use in pregnant women unless clearly necessary because it may cause foetal structural abnormalities or developmental toxicity, including lethality, growth retardation, and functional impairment of the nervous and reproductive systems. Consult your doctor before taking PEVESCA PLUS SR 75MG TABLET.

Q

Is PEVESCA PLUS SR 75MG TABLET safe to use in kidney patients?

A

PEVESCA PLUS SR 75MG TABLET should be used with caution in patients with renal impairment (complete or partial loss of kidney function). The dosage must be adjusted according to the disease status of such patients. Consult your doctor before taking PEVESCA PLUS SR 75MG TABLET.

Q

Is PEVESCA PLUS SR 75MG TABLET safe to use in heart patients?

A

PEVESCA PLUS SR 75MG TABLET should be used with caution in patients with congestive heart failure (complete or partial loss of heart function). The dosage must be adjusted according to the disease status of such patients. Consult your doctor before taking PEVESCA PLUS SR 75MG TABLET.

Q

Is it safe to drive while taking PEVESCA PLUS SR 75MG TABLET?

A

Do not drive or operate any machine if you feel dizziness and sleepiness after taking PEVESCA PLUS SR 75MG TABLET. Consult your doctor before driving if you need to take this medicine.

Article Information

DW

Written By

DETAILS Written By Dr. Dhivakaran R

Medical Content Writer

DS

Reviewed By

Dr. Sankara Babu Gorle

Medical Expert

Last Updated

16 Mar 2023

Tags

#neuropathic pain (649)#generic name folic acid 5 mg+methylcobalamin 1500 mcg+pregabalin 75 mg+pyridoxine 20 mg