Perinorm Syrup 60ml
Key Information
Generic Name
Generic Name Metoclopramide 5 mg
Manufacturer
Ipca Laboratories Ltd
Country of Origin
India
Detailed Information
Introduction
INTRODUCTION ABOUT PERINORM SYRUPPERINORM SYRUP contains Metoclopramide which belongs to the group of medicines called Anti-emetics. It is used to manage delayed nausea and vomiting in children (aged 1 to 18 years, when other medicines do not work or cannot be used to manage it) and adults that may occur after chemotherapy. PERINORM SYRUP is also used in adults to manage nausea and vomiting caused by radiotherapy and manages nausea and vomiting which may occur with a migraine. Migraine is a headache which ca
Uses
severe throbbing pain or pulsing sensation, particularly on one
How It Works
PERINORM SYRUP acts and supresses certain centres called dopamine (brain chemical) centres by decreasing the sensitivity of the nerves that transmit signals from gastrointestinal tract to the vomiting centres in the brain. It also relaxes the muscles of stomach and enhances the motility of gut and manages nausea and vomiting.
Directions for Use
Take PERINORM SYRUP as advised by your physician. Shake well before use. Use a measuring cup or a spoon to properly measure the dose. Your doctor will determine the correct dose and duration for you depending on your age, body weight and disease condition.
Side Effects
taking PERINORM SYRUP are drowsiness, restlessness, feeling weak, uncontrollable body movements (such as muscle stiffness or rigidity) and diarrhoea. Consult your physician immediately if any of the side effects worsen. USES OF PERINORM SYRUP Prevents delayed nausea and vomiting that occurs after chemotherapy (in children (aged 1 to 18 years) and adults) Prevents nausea and vomiting caused by radiotherapy Manage nausea and vomiting that may occur with migraine HOW PERINORM SYRUP WORKSPERINORM SYRUP acts and supresses certain centres called dopamine (brain chemical) centres by decreasing the sensitivity of the nerves that transmit signals from gastrointestinal tract to the vomiting centres in the brain. It also relaxes the muscles of stomach and enhances the motility of gut and manages nausea and vomiting. DIRECTIONS FOR USETake PERINORM SYRUP as advised by your physician. Shake well before use. Use a measuring cup or a spoon to properly measure the dose. Your doctor will determine the correct dose and duration for you depending on your age, body weight and disease condition. SIDE EFFECTS OF PERINORM SYRUPCOMMON drowsiness uncontrollable movements such as shaking, tics, twisting movements or muscle contracture (stiffness, rigidity) rigidity and tremor (similar to Parkinson’s disease) diarrhoea feeling weak restlessness UNCOMMON elevated levels of hormone called prolactin (which may cause milk secretion in men and women who are not breastfeeding) irregular periods hallucination reduced consciousness allergy visual problems and involuntary deviation of eyeball RARE confusional state convulsions (especially in patients with fits) Stop taking PERINORM SYRUP and contact your doctor immediately if you experience any of the following side effects: signs of severe allergic reactions (such as swelling of the face, lips, tongue, throat and difficulties in breathing) signs of a brain disorder called neuroleptic malignant syndrome (such as sweating, high fever, high blood pressure, convulsions and production of saliva) uncontrollable movements of head and neck (occurs in children or young adults)
Warnings & Precautions
& PRECAUTIONSPREGNANCYPERINORM SYRUP should be used with caution in pregnant women or women who are planning to become pregnant only if clearly advised by your doctor. Consult your doctor before taking it. BREASTFEEDINGPERINORM SYRUP is not recommended for use in breastfeeding women as it may pass through the breast milk and affect the baby. Consult your doctor before taking it. DRIVING AND USING MACHINESDo not drive or operate any machines if you feel dizzy, drowsy or have uncontrollable twitching, jerking or writhing movements and unusual muscle tone leading to distortion of the body or your vision gets affected after taking PERINORM SYRUP. ALCOHOLAvoid consumption of alcohol while taking PERINORM SYRUP because it may increase the effect of sleepiness and drowsiness. KIDNEYPERINORM SYRUP should be used with caution in patients with kidney problems. Lower doses may be given to patients having moderate or severe kidney problems. Consult with your doctor before taking PERINORM SYRUP. LIVERPERINORM SYRUP should be used with caution in patients with liver problems. Lower doses may be given to patients having severe liver problems. Consult with your doctor before taking PERINORM SYRUP. ALLERGYDo not take PERINORM SYRUP if you are allergic to Metoclopramide or any of its constituents. HEART DISEASEPERINORM SYRUP should be used with caution in patients having heart diseases such as history of abnormal heart beats (QT interval prolongation, seen in an ECG) or any other heart problems. Consult with your doctor before taking PERINORM SYRUP. OTHERSPERINORM SYRUP is not recommended for use if you: have bleeding, obstruction or a tear in your stomach or gut have or may have a rare tumour of adrenal gland called pheochromocytoma have ever had involuntary muscle spasms (when managed with any medicine in the past) have epilepsy (seizures or fits) have parkinson’s disease (brain disorder causing uncontrollable movements of the body) have abnormal levels of blood pigments (methemoglobinemia or NADH cytochrome b5 deficiency) Before taking PERINORM SYRUP, inform your doctor if you: have problems with the levels of salts in the blood such as potassium, sodium or magnesium have any brain problems Use in paediatrics: PERINORM SYRUP is not recommended for use in children (below 1 year of age) because of the increased risk of uncontrollable movements. PERINORM SYRUP should be used with caution in children and adolescents (between age of 1 to 18 years) to manage delayed nausea and vomiting after chemotherapy. Your child’s doctor may adjust the dose depending on the child’s age and body weight. Consult your child’s doctor for advice. Use in geriatrics: PERINORM SYRUP should be used with caution in elderly patients and your doctor may adjust the dose depending on kidney and liver function and overall health condition. Consult your doctor before taking it.
Drug Interactions
SA. Drug - Drug interactions: Before taking PERINORM SYRUP, inform your doctor if you have received or taking any of the following medicines: medicines used to manage a brain disorder called Parkinson’s disease (Ex. levodopa, carbidopa, entacapone, tolcapone) anticholinergics (medicines used to manage stomach cramps and spasms) Ex. dicyclomine, hyoscyamine morphine derivatives (medicine used to manage severe pain) Ex. oxycodone, oxymorphone sedative medicines (used to manage sleeping disorders, anxiety or panic attacks) Ex. diazepam, lorazepam chlorpromazine, carbamazepine, lithium (used to manage mental health problems) medicines used to manage depression (Ex. fluoxetine, paroxetine) medicine used to manage heart failure (Ex. digoxin) ciclosporin (medicine used during organ transplant to avoid organ rejection) mivacurium and suxamethonium (medicines used to relax the muscles) Overdosage: If you or anyone else accidentally take too much of PERINORM SYRUP, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose are uncontrollable movements, feeling drowsy, troublesome consciousness, confusion, hallucinations and heart problems. SYNOPSIS Drug : Metoclopramide Pharmacological Category : Anti-emetics Therapeutic Indication : Prevents and manages nausea and vomiting Dosage Forms : Tablet, Capsule, Syrup, Injection MORE INFORMATION Keep out of the sight and reach of children. Store PERINORM SYRUP at room temperature below 25°C
Article Information
Written By
DETAILS Written By Dr. R. Dinesh John Rajkumar
Medical Content Writer
Reviewed By
Dr. Sankara Babu Gorle
Medical Expert
Last Updated
01 Dec 2022