PERAMPIL 4 Tablet 15's
Key Information
Generic Name
Generic Name Perampanel 4 mg
Manufacturer
Alkem Laboratories Ltd
Variant
15 Tablet(s) in a Strip
Country of Origin
India
Detailed Information
Introduction
PERAMPIL 4 TABLET contains Perampanel which belongs to the group of medicines called Anti-epileptics. It is used as an adjunctive therapy for partial-onset seizures with or without secondarily generalized seizures in patients with epilepsy aged 12 years and older. It is used in association with other antiepileptic drugs to manage seizures such as partial seizures with or without secondary generalisation in adults, adolescents and children (4 to 11 years of age). It is also used to manage generalized seizures (fits that affect all the brain and cause convulsions or starting spells) in adults, adolescents (12 years and above) and children (7 to 11 years of age). Seizure is a disorder in which nerve cell activity in the brain is disturbed and during seizures person may experience abnormal behaviour, symptoms and sensations including loss of consciousness. PERAMPIL 4 TABLET is not recommended for use in patients with serious liver problems, moderate or serious kidney problems or patients allergic to perampanel or if you have ever developed a severe skin rash or skin peeling, blistering or mouth sores after taking perampanel. It should be used with caution in patients having a history of substance abuse. PERAMPIL 4 TABLET is not recommended for use in pregnant women or women planning for pregnancy and in breastfeeding women. PERAMPIL 4 TABLET is not recommended for use in children below 4 years of age (for partial seizures) and children below 7 years of age (for generalized seizures). The most common
Uses
OF PERAMPIL 4 TABLETIt is used in combination with other antiepileptics to manage certain types of epilepsy: Partial seizures (with or without generalized seizures) Generalized seizures
How It Works
PERAMPIL 4 TABLET blocks certain chemicals that regulate a broad spectrum of processes in the brain, spinal cord, retina, and nerves. These chemicals are excessively produced during the sudden disruption of the brain’s normal electrical activity that results in epileptic fits. This inhibitory action enables sufficient control over seizures without substantial impairment of brain function.
Directions for Use
Take PERAMPIL 4 TABLET as advised by your physician. Swallow the medicine whole with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
Side Effects
PERAMPIL 4 TABLET are dizziness, drowsiness, weight gain, irritable, anxious, or confusion. Talk to your doctor if any of the side effects gets worse over a longer duration. USES OF PERAMPIL 4 TABLETIt is used in combination with other antiepileptics to manage certain types of epilepsy: Partial seizures (with or without generalized seizures) Generalized seizures HOW PERAMPIL 4 TABLET WORKSPERAMPIL 4 TABLET blocks certain chemicals that regulate a broad spectrum of processes in the brain, spinal cord, retina, and nerves. These chemicals are excessively produced during the sudden disruption of the brain’s normal electrical activity that results in epileptic fits. This inhibitory action enables sufficient control over seizures without substantial impairment of brain function. DIRECTIONS FOR USETake PERAMPIL 4 TABLET as advised by your physician. Swallow the medicine whole with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition. SIDE EFFECTS OF PERAMPIL 4 TABLETCOMMON dizziness drowsiness increased or decreased appetite weight gain feeling aggressive, angry, irritable, anxious, or confused signs of ataxia, gait disturbance, balance disorder (difficulty with walking or balance) dysarthria (slow speech) diplopia (blurred vision or double vision) vertigo (head spinning sensation) nausea back pain tiredness headache RARE self-harming thoughts Stop taking PERAMPIL 4 TABLET and contact your doctor immediately if you experience any of the following side effects: Signs of drug reaction with eosinophilia and systemic symptoms (DRESS) known as drug hypersensitivity syndrome (widespread skin rash, high body temperature, swelling of lymph nodes and other body organs involvement) Signs of Stevens - Johnson syndrome (serious skin rash appearing as reddish target-like circular patches with central blisters on the trunk, skin peeling, ulcers of mouth, throat, nose, genitals, and eyes; and flu-like symptoms)
Warnings & Precautions
& PRECAUTIONSPREGNANCYContraindicatedPERAMPIL 4 TABLET is not recommended for use in pregnant women. Women of child-bearing potential should use reliable method of contraception to avoid becoming pregnant while taking PERAMPIL 4 TABLET, also continue this for one month after stopping the management. Consult your doctor before taking PERAMPIL 4 TABLET. BREASTFEEDINGMonitoring requiredPERAMPIL 4 TABLET is generally not recommended for use in breastfeeding women unless considered clearly necessary. Consult your doctor before taking PERAMPIL 4 TABLET. DRIVING AND USING MACHINESUse with CautionDo not drive or operate any machines if you feel dizzy or sleepy after taking PERAMPIL 4 TABLET. Consult your doctor before taking PERAMPIL 4 TABLET. ALCOHOLConsult your doctorAvoid consumption of alcohol while taking PERAMPIL 4 TABLET because it might make you dizzier and can also worsen the feelings of anger, confusion, or sadness. Consult your doctor before taking PERAMPIL 4 TABLET. KIDNEYContraindicatedPERAMPIL 4 TABLET is not recommended for use in patients with moderate or serious kidney problems. Consult with your doctor before taking PERAMPIL 4 TABLET. LIVERConsult your doctorPERAMPIL 4 TABLET is not recommended for use in patients with serious liver problems and it should be used with caution in patients with liver problems. Consult with your doctor before taking PERAMPIL 4 TABLET. ALLERGYContraindicatedDo not take PERAMPIL 4 TABLET if you are allergic to Perampanel or any other ingredients of this medicine. USE IN PEDIATRICSConsult your doctorPERAMPIL 4 TABLET is generally not recommended for use in children under 4 years of age for partial seizures and under 7 years of age for generalized seizures due to lack of safety and effectiveness. It should be used with caution in children (4 to 11 years of age) for partial seizures and (7 to 11 years of age) for generalized seizures. Your doctor will adjust the dose based on the body weight. Consult your doctor before taking this PERAMPIL 4 TABLET. USE IN GERIATRICSUse with CautionPERAMPIL 4 TABLET should be used with caution in elderly patients (aged 65 years and above). Consult your doctor before taking PERAMPIL 4 TABLET. OTHERSBefore taking PERAMPIL 4 TABLET, inform your doctor if you: have a history of substance abuse have psychiatric problems or have had depression, mood problems, aggressive or hostile behaviour or self-harming thoughts
Drug Interactions
SA. Drug-Drug interactions: Before taking PERAMPIL 4 TABLET, inform your doctor if you are taking any of the following medicine: Medicines used in the management of epilepsy (Ex. carbamazepine, oxcarbazepine, phenytoin, felbamate, midazolam) Rifampicin (used in management of bacterial infections) St. John’s Wort (herbal medicine used in the management of mild anxiety) Ketoconazole (medicine used in management of fungal infections) Hormonal contraceptives such as levonorgestrel including implants, injections, and patches Overdosage: If you or anyone else accidentally take too much of PERAMPIL 4 TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose are confusion, agitation, aggressive behaviour, and depressed level of consciousness. SYNOPSIS Drug : Perampanel Pharmacological Category : Antiepileptics Therapeutic Indication : Partial, Generalized seizures Dosage Forms : Tablet MORE INFORMATIONSTORAGE Keep PERAMPIL 4 TABLET out of reach of children Store at room temperature
Frequently Asked Questions
Common questions and answers about PERAMPIL 4 Tablet 15's.
What is PERAMPIL 4 TABLET used for?
It is used as an adjunctive therapy for partial-onset seizures with or without secondarily generalized seizures in patients with epilepsy aged 12 years and older.
What should I avoid while taking PERAMPIL 4 TABLET?
Avoid consuming alcohol while taking PERAMPIL 4 TABLET because it might make you sleepier and dizzier. You should also avoid driving and using heavy machinery after taking PERAMPIL 4 TABLET and consult your concern with your doctor before starting to take this medicine.
What will happen if I suddenly stop taking PERAMPIL 4 TABLET?
You should not suddenly stop taking PERAMPIL 4 TABLET. Take as long as your doctor recommends. PERAMPIL 4 TABLET can cause physical dependence, which means that abruptly discontinuing can result in symptoms such as anxiety, nervousness, irritability, fatigue, weakness, lethargy, mood swings, and sleeplessness.
What are the health tips to be followed while taking PERAMPIL 4 TABLET to manage seizures?
Take a healthy diet along with regular exercise, practice yoga every day, get enough sleep, limit the use of screen time such as mobile or laptop and remember to take PERAMPIL 4 TABLET on time. Follow these health tips after consulting your doctor.
Does taking PERAMPIL 4 TABLET affect my mental health?
Yes, while taking PERAMPIL 4 TABLET you might experience extreme mood changes, increased aggressive behaviour and suicidal thoughts also might crop up in your mind. If any you experience any of these symptoms, please consult your doctor immediately.
Article Information
Written By
DETAILS Written By Dr. Janet.C
Medical Content Writer
Reviewed By
Dr. Sankara Babu Gorle
Medical Expert
Last Updated
05 Jul 2024