Pemnat 500mg Injection 1's
Key Information
Generic Name
Generic Name Pemetrexed 500 mg
Manufacturer
Natco Pharma Ltd
Country of Origin
India
Detailed Information
Introduction
INTRODUCTION ABOUT PEMNAT 500MG INJECTIONPEMNAT 500MG INJECTION contains Pemetrexed which belongs to the group of medicines called Anticancer agents. It is used to manage advanced stages of non-small cell lung cancer (NSCLC). It can be used as a management option to control cancer progression in patients who have failed to respond adequately to conventional therapies. PEMNAT 500MG INJECTION is also used to manage malignant cancer of pleural membrane (a protective layer surrounding the lungs), called as pleural mesothelioma. It is mostly used in combination with other anti-cancer medicines (such as cisplatin, carboplatin) to achieve better results. Before receiving PEMNAT 500MG INJECTION inform your doctor if you have any lung, liver, kidney or heart problems or a previous history of the same. You must also inform your doctor if you have fluid accumulation in the lungs or recently received or planning to receive any radiation therapy or vaccination in the upcoming days as a precaution. PEMNAT 500MG INJECTION is not recommended for use in pregnant or breastfeeding women and in children aged below 18 years. Men and women receiving PEMNAT 500MG INJECTION must use a suitable contraceptive method to avoid pregnancy while undergoing therapy with PEMNAT 500MG INJECTION and for until 6 months after stopping the therapy. The most common
Uses
OF PEMNAT 500MG INJECTION Manage advanced non-small cell lung cancer (NSCLC) Manage malignant pleural mesothelioma (cancer of the protective layer of the lungs)
How It Works
PEMNAT 500MG INJECTION is an anticancer medication. It works by blocking the activity of certain enzymes (Ex. dihydrofolate reductase, thymidylate synthase etc.) in the body that may help cancer cells to grow and multiply. As a result, it reduces abnormal growth and multiplication of cancer cells in the body.
Directions for Use
PEMNAT 500MG INJECTION will be given to you only by a doctor or a nurse into a vein (as an intravenous infusion). Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition.
Side Effects
receiving PEMNAT 500MG INJECTION are increased infections, sore throat, nausea, vomiting, stomach pain, dizziness, tiredness, weight loss, changes in taste, skin rash, hair loss and mouth ulcers. Contact your doctor if any of these side effect worsens. USES OF PEMNAT 500MG INJECTION Manage advanced non-small cell lung cancer (NSCLC) Manage malignant pleural mesothelioma (cancer of the protective layer of the lungs) HOW PEMNAT 500MG INJECTION WORKSPEMNAT 500MG INJECTION is an anticancer medication. It works by blocking the activity of certain enzymes (Ex. dihydrofolate reductase, thymidylate synthase etc.) in the body that may help cancer cells to grow and multiply. As a result, it reduces abnormal growth and multiplication of cancer cells in the body. DIRECTIONS FOR USEPEMNAT 500MG INJECTION will be given to you only by a doctor or a nurse into a vein (as an intravenous infusion). Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition. SIDE EFFECTS OF PEMNAT 500MG INJECTIONCOMMON infections, fever, sore throat hair loss nausea, vomiting, loss of appetite stomach pain, indigestion, constipation, diarrhea mouth ulcers (pain, redness, swelling on the mouth) tiredness, dehydration, dizziness skin rash (marks may resemble bull’s eye) flaky skin, loss of sensation on the skin, increased skin pigmentation changes in taste muscle weakness or wasting, unsteady movements eye inflammation, dry eyes, eye swelling, eye irritation, tearing irregular heartbeat increase in liver and kidney enzymes swelling of body parts inflammation of the gut UNCOMMON rectal inflammation or bleeding inflammation and redness of esophagus RAREContact your doctor immediately if you experience any of the following side effects after receiving PEMNAT 500MG INJECTION: fever, increased infections, sepsis (infections of the blood) chest pain, fast heart rate inflammation of the mouth with pain, redness and swelling signs of allergic reactions (such as skin rash, swelling of the face, lips, mouth, or throat which can lead to difficulty in breathing or swallowing) severe skin reactions with blistering and peeling of skin, burning or prickling sensation or fever signs of low RBC in blood (tiredness, pale skin, fainting, breathlessness) increased tendency to bleed (such as bleeding gums, bleeding from the nose or mouth) unexpected bruising signs of blood clot in lungs (such as breathlessness, heavy chest pain or cough with bloody sputum)
Warnings & Precautions
& PRECAUTIONSPREGNANCYPEMNAT 500MG INJECTION is generally not recommended for use in pregnant women due to increased risk of side effects. Women of childbearing potential must use a suitable contraceptive to avoid pregnancy while undergoing therapy with PEMNAT 500MG INJECTION. If you accidentally became pregnant while receiving PEMNAT 500MG INJECTION, inform your doctor immediately. BREASTFEEDINGPEMNAT 500MG INJECTION is generally not recommended for use in breastfeeding women as it may pass through breast milk. Therefore, consult your doctor before receiving it. DRIVING AND USING MACHINESDo not drive or operate any machines if you feel tired after receiving PEMNAT 500MG INJECTION. KIDNEYPEMNAT 500MG INJECTION should be used with caution in patients with kidney problems. It should also be used with caution in patients who has a previous history of kidney problems. Therefore, consult your doctor before receiving it. LIVERPEMNAT 500MG INJECTION should be used with caution in patients with liver problems. Therefore, consult your doctor before receiving it. ALLERGYDo not receive PEMNAT 500MG INJECTION if you are allergic to pemetrexed or to any of the other ingredients of the medicines. LUNGSPEMNAT 500MG INJECTION should be used with caution in patients with fluid accumulation around the lungs. Therefore, consult your doctor before receiving it. HEART DISEASEPEMNAT 500MG INJECTION should be used with caution in patients with heart problems. It should also be used with caution in patients who has a previous history of heart problems. Therefore, consult your doctor before receiving it. OTHERSBefore receiving PEMNAT 500MG INJECTION inform your doctor if you: have had or are going to take radiation therapy have been recently vaccinated Use in pediatrics: PEMNAT 500MG INJECTION is generally not recommended for use in children and adolescents (under 18 years of age) due to lack of safety data. Therefore, consult your doctor before receiving it. Use in geriatrics: PEMNAT 500MG INJECTION should be used with caution in elderly patients (aged 65 years and above). Consult your doctor before receiving it.
Drug Interactions
SA. Drug-Drug interactions: Before receiving PEMNAT 500MG INJECTION inform your doctor if you are taking any of the following medicine: medicines used to manage pain and inflammation (Ex. ibuprofen) live or attenuated vaccines (Ex. yellow fever vaccine) Overdosage: PEMNAT 500MG INJECTION will be administered to you only by a doctor or nurse in a hospital, and so it is unlikely to receive an overdose. However, consult your physician or nurse if you experience any unusual symptoms. SYNOPSIS Drug : Pemetrexed Pharmacological Category : Folate Antagonists Therapeutic Indication : Advanced non-small cell lung cancer Dosage Forms : Injection MORE INFORMATION Keep PEMNAT 500MG INJECTION out of reach of children Store PEMNAT 500MG INJECTION at room temperature
Article Information
Written By
DETAILS Written By Srilekha. R
Medical Content Writer
Reviewed By
Dr. Sankara Babu Gorle
Medical Expert
Last Updated
16 Nov 2022