Pamorelin LA 11.25mg Injection 1's

Hormonal Therapy (615)Rx required

Key Information

Generic Name

Generic Name Triptorelin 11.25 mg

Manufacturer

Dr. Reddy's Laboratories Ltd

Country of Origin

India

Detailed Information

Introduction

INTRODUCTION ABOUT PAMORELIN LA 11.25MG INJECTIONPAMORELIN LA 11.25MG INJECTION contains Triptorelin which belongs to the group of medicines called Gonadotropin-releasing hormone (GnRH) agonists. PAMORELIN LA 11.25MG INJECTION is used in men to manage prostate cancer and in women to reduce the size of uterine fibroids (non-cancerous tumours arising from the smooth muscle layer of the uterus) and to manage endometriosis (a condition in which the tissue that normally lines the uterus grows in other places). PAMORELIN LA 11.25MG INJECTION can also be used in children to manage central precocious puberty (puberty that occurs before 8 years in girls and 10 years in boys). PAMORELIN LA 11.25MG INJECTION should be used with caution in patients with high blood pressure, liver, kidney and heart diseaase, diabetes, benign tumour of pituitary gland or have pains in bones and difficulty passing urine. Consult your doctor before receiving it. PAMORELIN LA 11.25MG INJECTION is not recommended for use in pregnant and breast-feeding women. PAMORELIN LA 11.25MG INJECTION should be used with caution in children (girls under 9 years of age and boys under 10 years of age) for the management of early puberty. Consult your doctor before receiving it. The most common

Uses

OF PAMORELIN LA 11.25MG INJECTIONPAMORELIN LA 11.25MG INJECTION is used in men to manage prostate cancer in women to reduce uterine fibroids and to manage endometriosis in children to manage central precocious puberty

How It Works

PAMORELIN LA 11.25MG INJECTION is similar to the gonadotropin releasing hormone which occurs naturally in your body. In men, PAMORELIN LA 11.25MG INJECTION lowers the levels of the hormone testosterone and helps to manage prostate cancer. In women, it reduces oestrogen levels, helps to reduce the size of uterine fibroids and manages endometriosis. In children PAMORELIN LA 11.25MG INJECTION helps to supress gonadotropin (hormone) secretion in brain and helps to block pubertal development and also reduces the action of sex steroid hormones on bone maturation in order to restore normal long-term growth of the skeleton.

Directions for Use

PAMORELIN LA 11.25MG INJECTION will be given to you only by a doctor or a nurse as an intramuscular injection (into a muscle) or subcutaneous injection (just under the skin). Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition. Do not stop using PAMORELIN LA 11.25MG INJECTION unless your doctor advised you to stop. Otherwise, your symptoms are likely to return.

Side Effects

receiving PAMORELIN LA 11.25MG INJECTION are hot flushes, weakness, excessive sweating, back pain, pins and needles sensation in the legs, reduced libido and impotence, nausea, dry mouth etc. Contact your doctor if any of the symptoms worsen. USES OF PAMORELIN LA 11.25MG INJECTIONPAMORELIN LA 11.25MG INJECTION is used in men to manage prostate cancer in women to reduce uterine fibroids and to manage endometriosis in children to manage central precocious puberty HOW PAMORELIN LA 11.25MG INJECTION WORKSPAMORELIN LA 11.25MG INJECTION is similar to the gonadotropin releasing hormone which occurs naturally in your body. In men, PAMORELIN LA 11.25MG INJECTION lowers the levels of the hormone testosterone and helps to manage prostate cancer. In women, it reduces oestrogen levels, helps to reduce the size of uterine fibroids and manages endometriosis. In children PAMORELIN LA 11.25MG INJECTION helps to supress gonadotropin (hormone) secretion in brain and helps to block pubertal development and also reduces the action of sex steroid hormones on bone maturation in order to restore normal long-term growth of the skeleton. DIRECTIONS FOR USEPAMORELIN LA 11.25MG INJECTION will be given to you only by a doctor or a nurse as an intramuscular injection (into a muscle) or subcutaneous injection (just under the skin). Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition. Do not stop using PAMORELIN LA 11.25MG INJECTION unless your doctor advised you to stop. Otherwise, your symptoms are likely to return. SIDE EFFECTS OF PAMORELIN LA 11.25MG INJECTIONCOMMON hot flushes weakness excessive sweating pins and needles sensation in the legs reduced libido and impotence nausea, dry mouth, abdominal pain bruising, redness and swelling at injection site muscle and bone pain, back pain, pain in the arms and legs oedema (build-up of fluid in the body tissues) allergic reaction increase in weight dizziness, headache depression and mood changes pain, swelling and tenderness nervousness difficulty in sleeping breast disorder, breast pain ovarian hyperstimulation syndrome pain during or after sexual intercourse painful periods, vaginal bleeding pelvic pain dryness of the vagina acne, oily skin UNCOMMON feeling your heartbeat ringing in the ears, vertigo blurred vision, dry eye bloating, flatulence, constipation, diarrhoea, vomiting severe shivering associated with sweating and a fever sleepiness increased weight loss change in appetite gout (severe pain and swelling in the joints usually in the big toe) diabetes muscle weakness feeling of irritability development of enlarged breasts in men, reduction in testicular size, pain in testicles difficulty in breathing hair loss waking up to pass urine, problems passing urine nosebleeds abnormal taste loss of sensations temporary loss of consciousness memory loss, lack of concentration, involuntary muscle movement anxiety, disorientation bleeding after sex prolapse irregular period, painful period and heavy period small cysts (swelling) on the ovaries which can cause pain, discharge from the vagina dry skin excessive bodily hair brittle nails RARE red or purple discolorations on the skin, blisters abnormal sensation in the eye chest pain trouble standing flu-like symptoms, fever inflammation of the nose or throat osteoarthritis decreased activity having a feeling of elation breathlessness when lying flat Stop receiving PAMORELIN LA 11.25MG INJECTION and contact your doctor immediately if you experience any of the following side effects: severe allergic reaction like angioedema or anaphylactic reaction (swallowing or breathing problems, dizziness, a rash, swelling of lips, face, throat or tongue) symptoms of brain hemorrhage (pituitary apoplexia) such as sudden headache, vomiting, problems with vision

Warnings & Precautions

& PRECAUTIONSPREGNANCYPAMORELIN LA 11.25MG INJECTION is not recommended for use in pregnant women. Consult your doctor before receiving PAMORELIN LA 11.25MG INJECTION. Use contraceptives method such as condom or diaphragm (cap) during management with PAMORELIN LA 11.25MG INJECTION and until menses resume. BREASTFEEDINGPAMORELIN LA 11.25MG INJECTION is not recommended for use in breastfeeding women. Consult your doctor before receiving PAMORELIN LA 11.25MG INJECTION. DRIVING AND USING MACHINESDo not drive or operate any machines if you have dizziness, tiredness, sleep disturbances or insomnia, blurry vision after receiving PAMORELIN LA 11.25MG INJECTION. ALCOHOLInform your doctor if you drink excessive amounts of alcohol as it might cause thinning of bones. KIDNEYPAMORELIN LA 11.25MG INJECTION should be used with caution in patients with kidney disease. Consult your doctor before receiving PAMORELIN LA 11.25MG INJECTION. LIVERPAMORELIN LA 11.25MG INJECTION should be used with caution in patients with liver disease. Consult your doctor before receiving PAMORELIN LA 11.25MG INJECTION. ALLERGYDo not receive PAMORELIN LA 11.25MG INJECTION if you are allergic to Triptorelin or similar other GnRH agonists or any of the other ingredients of PAMORELIN LA 11.25MG INJECTION. HEART DISEASEPAMORELIN LA 11.25MG INJECTION should be used with caution in patients with high blood pressure, heart rhythm problems, heart attack and heart failure. Consult your doctor before receiving PAMORELIN LA 11.25MG INJECTION. OTHERSBefore receiving PAMORELIN LA 11.25MG INJECTION, inform your doctor if you: or any of your family member have thinning of the bones smoke heavily have urinary obstruction or compressed nerves in your backbone due to spreading of your prostate cancer have surgical removal of testicles have diabetes (high blood sugar) have benign tumour of pituitary gland have pains in your bones or difficulty passing urine have back pain, weakness, numbness or tingling in your legs have progressive brain tumour (in children) have stroke, mini stroke have a low level of potassium, calcium or magnesium in your blood have a mental illness have fits Use in pediatrics: PAMORELIN LA 11.25MG INJECTION should be used with caution in children (girls under 9 years of age and boys under 10 years of age) for the management of early puberty. Consult your doctor before receiving PAMORELIN LA 11.25MG INJECTION. PAMORELIN LA 11.25MG INJECTION is not recommended for use in adolescents and young girls (under 18 years of age) for the management of endometriosis as it might cause thinning of bone. Consult your doctor before receiving it.

Drug Interactions

SA. Drug - Drug interactions: Before receiving PAMORELIN LA 11.25MG INJECTION, inform your doctor if you are taking any of the following medicine: medicines used to manage heart rhythm problems (Ex. quinidine, procainamide, amiodarone, sotalol) methadone (used to relieve pain and in drug dependence detoxification) moxifloxacin (used to manage bacterial infections) medicines used to manage serious mental illnesses (Ex. olanzapine, risperidone, haloperidol) medicines that increase the level of a hormone called prolactin (Ex. clomipramine) medicines used to delay blood clotting (Ex. heparin, warfarin) medicines used to manage fits (Ex. lamotrigine, carbamazepine) medicines used to manage inflammatory conditions (Ex. hydrocortisone, prednisolone) reserpine, methyldopa (used to manage high blood pressure) metoclopramide (used to manage nausea and vomiting) bupropion and selective serotonin reuptake inhibitors Ex. fluoxetine, sertraline and paroxetine (medicines used to manage depression) Overdosage: PAMORELIN LA 11.25MG INJECTION will be administered to you only by a doctor or a nurse in a hospital and so it is unlikely to receive an overdose. However, consult your doctor or nurse if you experience any unusual symptoms after receiving PAMORELIN LA 11.25MG INJECTION. SYNOPSIS Drug : Triptorelin Pharmacological Category : Gonadotropin-releasing hormone (GnRH) agonists Therapeutic Indication : Prostate cancer (men), Endometriosis, uterine fibroids (women), Central precocious puberty (children) Dosage Forms : Injection MORE INFORMATION Keep PAMORELIN LA 11.25MG INJECTION out of reach of children Store PAMORELIN LA 11.25MG INJECTION below 25°C

Article Information

I(

Written By

ity (HPRA). [Revised in October 2019] [Accessed on 11th June 2022] http://www.hpra.ie/img/uploaded/swedocuments/7143c597-b1e4-450f-9704-fc5131582ad9.pdf USEFUL DIAGNOSTIC TESTS Digital rectal exam (DRE) Prostate-specific antigen (PSA) test Laparoscopy GnRH stimulation test AUTHOR DETAILS Written By Dr. N. Sai Swaroop

Medical Content Writer

DS

Reviewed By

Dr. Sankara Babu Gorle

Medical Expert

Last Updated

11 Jan 2023

Tags

#hormonal therapy (615)#generic name triptorelin 11.25 mg