Ovral 28 Tablet 28'S
Key Information
Generic Name
Generic Name Ethinylestradiol 0.03 mg+Ferrous Fumarate 75 mg+Levonorgestrel 0.15 mg
Manufacturer
Pfizer Ltd
Variant
28 Tablet(s) in a Strip
Country of Origin
India
Detailed Information
Introduction
OVRAL 28 TABLET is a combination of Levonorgestrel and Ethinylestradiol which belongs to the group of medicines called Hormonal Contraceptive Agents. It is used as a contraceptive pill to manage pregnancy. Before taking OVRAL 28 TABLET inform your doctor if you have any lung, liver, kidney or heart problems. You must also inform your doctor if you have asthma, diabetes, high blood pressure, high blood cholesterol levels, migraine, obesity, epilepsy or depression as a precaution. OVRAL 28 TABLET is strictly not recommended for use in patients with breast cancer, cervical cancer or liver cancer. It is also not suitable for use in patients with depression, blood clots, stroke or any problems in blood circulation. OVRAL 28 TABLET is not intended for use in pregnant women, in children who have not attained puberty and elderly women who have reached menopause. It is also not recommended for use in breastfeeding women and in women (aged above 35 years) who have the habit of smoking. The most common
Uses
OF OVRAL 28 TABLET Used as a contraceptive to manage pregnancy
How It Works
OVRAL 28 TABLET is a contraceptive pill. It reduces the chances of pregnancy by suppressing ovulation (release of a mature egg from an ovary). It can also reduce the thickness of the inner lining of the uterus which makes it not suitable for the foetus to implant and grow. Additionally, it can alter the thickness of the cervical mucus which makes it difficult for the sperm to enter the uterus and fertilize the egg. As a result, they create an unfavourable environment for a successful pregnancy.
Directions for Use
Take OVRAL 28 TABLET strictly as advised by your physician. Swallow OVRAL 28 TABLET with a glass of water. Do not crush or chew the medicine. OVRAL 28 TABLET can be taken with or without meals. Do not miss any dose of OVRAL 28 TABLET in between the therapy, as it may reduce its effectiveness. In case you have missed a dose of OVRAL 28 TABLET, take it as soon as you remember. Avoid taking a double dose of this medicine to compensate for the missed dose. Your doctor will decide the correct dose and duration of therapy for you depending on your age, body weight and health condition.
Side Effects
taking OVRAL 28 TABLET are vaginal infections or inflammation, vaginal discharge, unusual spotting or bleeding, breast tenderness, milk discharge from breasts, mood changes, low sex drive, and changes in body weight. Consult your doctor if any of these side effects worsens. USES OF OVRAL 28 TABLET Used as a contraceptive to manage pregnancy HOW OVRAL 28 TABLET WORKSOVRAL 28 TABLET is a contraceptive pill. It reduces the chances of pregnancy by suppressing ovulation (release of a mature egg from an ovary). It can also reduce the thickness of the inner lining of the uterus which makes it not suitable for the foetus to implant and grow. Additionally, it can alter the thickness of the cervical mucus which makes it difficult for the sperm to enter the uterus and fertilize the egg. As a result, they create an unfavourable environment for a successful pregnancy. DIRECTIONS FOR USETake OVRAL 28 TABLET strictly as advised by your physician. Swallow OVRAL 28 TABLET with a glass of water. Do not crush or chew the medicine. OVRAL 28 TABLET can be taken with or without meals. Do not miss any dose of OVRAL 28 TABLET in between the therapy, as it may reduce its effectiveness. In case you have missed a dose of OVRAL 28 TABLET, take it as soon as you remember. Avoid taking a double dose of this medicine to compensate for the missed dose. Your doctor will decide the correct dose and duration of therapy for you depending on your age, body weight and health condition. SIDE EFFECTS OF OVRAL 28 TABLETCOMMON vaginal infection, itching or inflammation discharge from vagina changes in body weight changes in mood (mood swings) depression changes in sex drive headache, tiredness feeling nervous nausea, vomiting, stomach pain unusual spotting or bleeding breast pain or tenderness milk discharge from breasts heavy periods or lack of periods swelling of body parts (edema) UNCOMMON changes in blood cholesterol levels changes in appetite increase in blood pressure flatulence (bloating) skin rashes, dark patches on the skin hirsutism (abnormal hair growth in the body) hair loss RARE decrease in serum folate levels unable to wear contact lenses cholestatic jaundice Stop taking OVRAL 28 TABLET and contact your doctor immediately if you experience any of the following side effects: signs of allergic reactions (such as swelling of the face, lips, mouth, tongue, or throat causing difficulty in breathing or swallowing) signs of breast cancer (presence of lumps in the breast, skin dimpling in the breast and changes in the nipple) signs of cervical cancer (smelly or bloody discharge from the vagina, unusual vaginal bleeding, pelvic pain, and painful sex) signs of severe liver problems (such as severe pain in your upper abdomen, yellow skin, or eyes, itching in the whole body) signs of a blood clot in the legs (such as swelling of the affected leg or foot accompanied by pain or tenderness) signs of a blood clot in the lungs (such as sudden unexplained breathing difficulty, rapid heart rate, sharp chest pain, severe lightheadedness, or dizziness) signs of a blood clot in the eyes (such as sudden loss of vision or painless blurring of vision) signs of heart attack (chest pain, pressure, heaviness in the chest, abnormal heartbeat, extreme weakness, anxiety, or shortness of breath, sweating, nausea, vomiting or dizziness) signs of stroke (sudden weakness or numbness of the face, arm, or legs, especially on one side of the body, confusion, trouble in speaking or understanding, walking, dizziness, loss of balance, fainting with or without seizure) swelling and slight blue discolouration of an extremity, severe stomach pain feeling depressed with thoughts of killing or harming yourself
Warnings & Precautions
& PRECAUTIONSPREGNANCYOVRAL 28 TABLET is not recommended for use in pregnant women and in women who think that they might be pregnant. It is also not recommended for use in women who have or ever had jaundice due to pregnancy. It should be used with caution in pregnant women with a previous history of herpes gestationis (an autoimmune skin disease). Therefore, consult your doctor before taking it. BREASTFEEDINGOVRAL 28 TABLET is not recommended for use in breast-feeding women. Therefore, consult your doctor before taking it. DRIVING AND USING MACHINESOVRAL 28 TABLET has negligible effects on driving or handling heavy tools or machines. However, do not drive or handle any heavy machines if your ability is affected by OVRAL 28 TABLET. ALCOHOLAvoid consumption of alcohol while taking OVRAL 28 TABLET. KIDNEYOVRAL 28 TABLET is not recommended for use in patients with kidney diseases (such as kidney failure). It should be used with caution in patients with other kidney problems. Therefore, consult your doctor before taking it. LIVEROVRAL 28 TABLET is not recommended for use in patients who have or ever had liver diseases (such as liver tumours). It should be used with caution in patients with other liver or gallbladder problems (such as jaundice, and gallstones). Therefore, consult your doctor before taking it. ALLERGYDo not take OVRAL 28 TABLET if you are allergic to Levonorgestrel or Ethinylestradiol. LUNGSOVRAL 28 TABLET is not recommended for use in patients who have blood clots in the lungs (pulmonary embolism). It should be used with caution in patients with asthma. Therefore, consult your doctor before taking it. HEART DISEASEOVRAL 28 TABLET is not recommended for use in patients who have or ever had heart diseases (such as coronary artery disease, heart attack, angina, valvular heart disease, or arrhythmias). It should be used with caution in patients with other heart problems. Therefore, consult your doctor before taking it. OTHERSOVRAL 28 TABLET is not recommended for use if you: have or had blood clots in legs (deep vein thrombosis) or eyes (retinal thrombosis) have any type of blood clotting disorders (such as APC resistance, protein C deficiency, protein S deficiency, antithrombin-III deficiency, antiphospholipid antibodies in blood which cause immediate blood clots) have any pre-planned surgery have severe diabetes with damage to blood vessels have uncontrolled high blood pressure have high blood cholesterol and triglyceride levels have or ever had migraine headaches have or ever had or at risk of developing breast cancer or cancers in genital organs have hyperhomocysteinaemia (an increase in the levels of an amino acid called homocysteine in blood) have unexplained bleeding from the vagina have pancreatitis (severe inflammation of the pancreas) have hepatitis C infection (a type of viral infection affecting the liver) have adrenal insufficiency (when the body does not produce enough aldosterone hormone) are aged above 35 years and have a habit of smoking have stroke or problems in blood circulation have reached menopause Before taking OVRAL 28 TABLET inform your doctor if you: have family history of breast cancer have hypertension have depression have diarrhoea/vomiting have otosclerosis (abnormal bone growth in the ears) have Crohn’s disease or ulcerative colitis (chronic inflammatory bowel disease) have systemic lupus erythematosus (disease affecting your immune system) have haemolytic uraemic syndrome (blood clotting disorder causing kidney failure) have sickle cell anaemia (an inherited red blood cell disease) have just given birth had an abortion in the second trimester have been bed-ridden or immobile for a prolonged period have an inflammation in the veins under the skin (superficial thrombophlebitis) have varicose veins (enlarged or twisted veins) have epilepsy are obese have porphyria (a rare inherited blood disorder) have abnormal body movements (chorea) have multiple sclerosis (an autoimmune disease, causing nerve damage) have tetany (involuntary muscle contractions) have a history of chloasma gravidarum (dark patches on the skin) in previous pregnancies are due to have a lab test Use in paediatrics: OVRAL 28 TABLET is not recommended for use in children and in adolescent girls aged below 18 years. It is also not intended for use in female children who have not attained puberty. Therefore, consult your doctor before taking it. Use in geriatrics: OVRAL 28 TABLET is not indicated for use in elderly women. Therefore, consult your doctor before taking it.
Drug Interactions
SA. Drug - Drug interactions: Before taking OVRAL 28 TABLET, inform your doctor if you are taking any of the following medicines such as: medicines used to manage epilepsy (Ex. primidone, phenytoin, topiramate, phenobarbital, carbamazepine, oxcarbazepine, felbamate, lamotrigine) medicines used to manage tuberculosis (Ex. rifampicin, rifabutin) dexamethasone (a medicine used to manage asthma or autoimmune diseases) atorvastatin (a medicine used to manage high blood cholesterol levels) modafinil (a medicine used to reduce sleep in narcolepsy) troleandomycin (a medicine used to manage bacterial infections) ascorbic acid (a vitamin C supplement) medicines used to manage HIV infection (Ex. ritonavir, nevirapine, efavirenz) medicines used to manage fungal infections (Ex. fluconazole, griseofulvin) St. John’s wort (an herbal remedy used to manage mental illness) medicines used to manage graft rejection during organ transplants (Ex. cyclosporin) theophylline (used to manage breathing problems) flunarizine (a medicine used to manage vertigo) medicines used to manage hepatitis C infections (Ex. ombitasvir, paritaprevir, ritonavir and dasabuvir) medicines used to relive pain (Ex. ibuprofen, aceclofenac, phenylbutazone, paracetamol) heparin (a medicine used to manage blood clots) Overdosage: If you or anyone else accidentally took more OVRAL 28 TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose might include nausea, vomiting, breast tenderness, dizziness, stomach pain, fatigue and withdrawal bleeding. SYNOPSIS Drug : Levonorgestrel, Ethinylestradiol Pharmacological Category : Synthetic Progestins, Estrogens Therapeutic Indication : Contraception Dosage Forms : Tablet MORE INFORMATION Keep OVRAL 28 TABLET out of reach of children Store OVRAL 28 TABLET at room temperature
Article Information
Written By
DETAILS Written By Srilekha. R
Medical Content Writer
Reviewed By
Dr. Sankara Babu Gorle
Medical Expert
Last Updated
22 Dec 2022