NINDEV 100mg Soft Gelatin Capsule 10's
Key Information
Generic Name
Generic Name Nintedanib 100 mg
Manufacturer
Zydus Healthcare Ltd
Variant
10 Capsule(s) in a Strip
Country of Origin
India
Detailed Information
Introduction
INTRODUCTION ABOUT NINDEV 100MG SOFT GELATIN CAPSULENINDEV 100MG SOFT GELATIN CAPSULE contains Nintedanib which belongs to the group of medicines called Kinase inhibitors. It is used to manage idiopathic pulmonary fibrosis (IPF), chronic fibrosing interstitial lung diseases (ILDs) with a progressive phenotype, slowing the rate of decline in pulmonary function in patients with systemic sclerosis-associated interstitial lung disease (SSc-ILD). It is used in combination with docetaxel in adult patients for the management of locally advanced metastatic or recurrent non-small cell lung cancer (NSCLC) of adenocarcinoma tumor histology after first line chemotherapy. Idiopathic Pulmonary Fibrosis (IPF) is a chronic lung disorder in which the lungs become scarred and breathing becomes increasingly difficult. Symptoms include shortness of breath, persistent dry cough, tiredness, loss of appetite, weight loss, rounded and swollen fingertips (clubbed fingers). Before taking NINDEV 100MG SOFT GELATIN CAPSULE inform your doctor if you have liver, heart or bleeding problems, history of blood clots or had a recent surgery in stomach. NINDEV 100MG SOFT GELATIN CAPSULE is not recommended for use in pregnant women unless advised by your doctor and it is not recommended for use in breastfeeding women as it may pass through breast milk. Before starting management with NINDEV 100MG SOFT GELATIN CAPSULE, your doctor may want you to take several blood tests to understand your existing condition. NINDEV 100MG SOFT GELATIN CAPSULE should be used with caution in elderly patients (aged 65 years and above). The most common
Uses
OF NINDEV 100MG SOFT GELATIN CAPSULE Manage idiopathic pulmonary fibrosis (IPF) Manage chronic fibrosing interstitial lung diseases (ILDs) with a progressive phenotype To slow the rate of decline in pulmonary function in patients with systemic sclerosis-associated interstitial lung disease (SSc-ILD)
How It Works
NINDEV 100MG SOFT GELATIN CAPSULE is a tyrosine kinase inhibitor (TKI) which works by blocking the enzymes in cells of the lungs called tyrosine kinases. Blocking these enzymes helps to decrease fibrous tissue formation in the lungs, thereby stops the symptoms of lung disease getting worse.
Directions for Use
Take NINDEV 100MG SOFT GELATIN CAPSULE as advised by your physician. Swallow the medicine with a glass of water. Do not crush, chew, or open the medicine. Your doctor will decide the correct dose and duration for you based upon your age, body weight and disease condition. Do not stop taking NINDEV 100MG SOFT GELATIN CAPSULE unless your doctor advises you to stop.
Side Effects
taking NINDEV 100MG SOFT GELATIN CAPSULE are diarrhoea, nausea, vomiting, stomach pain, loss of appetite, headache, weight loss and high blood pressure. Consult your doctor if any of the symptom worsens. USES OF NINDEV 100MG SOFT GELATIN CAPSULE Manage idiopathic pulmonary fibrosis (IPF) Manage chronic fibrosing interstitial lung diseases (ILDs) with a progressive phenotype To slow the rate of decline in pulmonary function in patients with systemic sclerosis-associated interstitial lung disease (SSc-ILD) HOW NINDEV 100MG SOFT GELATIN CAPSULE WORKSNINDEV 100MG SOFT GELATIN CAPSULE is a tyrosine kinase inhibitor (TKI) which works by blocking the enzymes in cells of the lungs called tyrosine kinases. Blocking these enzymes helps to decrease fibrous tissue formation in the lungs, thereby stops the symptoms of lung disease getting worse. DIRECTIONS FOR USETake NINDEV 100MG SOFT GELATIN CAPSULE as advised by your physician. Swallow the medicine with a glass of water. Do not crush, chew, or open the medicine. Your doctor will decide the correct dose and duration for you based upon your age, body weight and disease condition. Do not stop taking NINDEV 100MG SOFT GELATIN CAPSULE unless your doctor advises you to stop. SIDE EFFECTS OF NINDEV 100MG SOFT GELATIN CAPSULECOMMON diarrhoea nausea, vomiting stomach pain liver problems decreased appetite headache weight loss high blood pressure RAREStop taking NINDEV 100MG SOFT GELATIN CAPSULE and contact your doctor immediately if you experience any of the following side effects: severe liver problems symptoms such as yellowing of your skin or white part of your eyes (jaundice), dark or brown (tea colored) urine, pain on the upper right side of your stomach area (abdomen), bleeding or bruising more easily than normal, feeling tired, or loss of appetite severe diarrhoea, nausea and vomiting signs of heart attack such as chest pain or pressure, pain in arms, back, neck or jaw, or shortness of breath signs of stroke such as numbness or weakness on one side of your body, trouble talking, headache or dizziness signs of bleeding problem such as unusual bleeding, bruising, or wounds that do not heal signs of tear in stomach or intestinal wall (perforation) such as pain or swelling in stomach area signs of increased protein in urine (proteinuria) such as foamy urine, swelling of the hands, arms, legs, or feet or sudden weight gain
Warnings & Precautions
& PRECAUTIONSPREGNANCYMonitoring requiredNINDEV 100MG SOFT GELATIN CAPSULE is not recommended for use in pregnant women unless considered clearly necessary. Consult your doctor before taking it. BREASTFEEDINGContraindicatedNINDEV 100MG SOFT GELATIN CAPSULE is not recommended for use in breastfeeding women as it may pass through breast milk. Consult your doctor before taking it. LIVERUse with CautionNINDEV 100MG SOFT GELATIN CAPSULE should be taken with caution in patients with liver problems. Consult your doctor before taking it. ALLERGYContraindicatedDo not take NINDEV 100MG SOFT GELATIN CAPSULE if you are allergic to Nintedanib or any of the other ingredients of this medicine. HEART DISEASEUse with CautionNINDEV 100MG SOFT GELATIN CAPSULE should be taken with caution in patients with heart problems. Consult your doctor before taking it. USE IN PEDIATRICSConsult your doctorThere is no proper information regarding the use of this medicine in children. Consult child’s doctor for advice USE IN GERIATRICSUse with CautionNINDEV 100MG SOFT GELATIN CAPSULE should be used with caution in elderly patients (aged 65 years and above). Consult your doctor before taking NINDEV 100MG SOFT GELATIN CAPSULE OTHERSBefore taking NINDEV 100MG SOFT GELATIN CAPSULE inform your doctor if you: have history of blood clots have bleeding problem or a family history of bleeding problem had recent surgery in stomach (abdominal) area are a smoker
Drug Interactions
SA. Drug - Drug interactions: Before taking NINDEV 100MG SOFT GELATIN CAPSULE inform your doctor if you are taking any of the following medicines: st. john’s wort (used to manage depression) laxatives such as bisacodyl, stool softeners such as lactulose (used to manage constipation) other medicines or dietary supplements (used to manage diarrhoea) blood thinners such as warfarin (used to manage or manage blood clots) aspirin (used to manage fever and pain) Overdosage: If you or anyone else accidentally take too much of NINDEV 100MG SOFT GELATIN CAPSULE, consult your doctor immediately or visit the nearby hospital. SYNOPSIS Drug : Nintedanib Pharmacological Category : Tyrosine Kinase Inhibitor Therapeutic Indication : Idiopathic pulmonary fibrosis (IPF), Chronic fibrosing interstitial lung diseases (ILDs) with a progressive phenotype, slows the rate of decline in pulmonary function in patients with systemic sclerosis-associated interstitial lung disease (SSc-ILD) Dosage Forms : Capsule MORE INFORMATION Keep NINDEV 100MG SOFT GELATIN CAPSULE out of reach of children Store at room temperature
Frequently Asked Questions
Common questions and answers about NINDEV 100mg Soft Gelatin Capsule 10's.
Can I take NINDEV 100MG SOFT GELATIN CAPSULE during pregnancy?
NINDEV 100MG SOFT GELATIN CAPSULE is not recommended for use in pregnant women unless clearly advised by your doctor. Consult your doctor before taking NINDEV 100MG SOFT GELATIN CAPSULE if you are pregnant or planning to get pregnant.
What to do If I forget to take a dose of NINDEV 100MG SOFT GELATIN CAPSULE?
You should take NINDEV 100MG SOFT GELATIN CAPSULE immediately when you remember. If it is time for your next dose skip the missed dose and follow your regular dose schedule. Do not double the dose to match up your missed dose.
Can I stop taking NINDEV 100MG SOFT GELATIN CAPSULE on my own?
Do not stop taking NINDEV 100MG SOFT GELATIN CAPSULE unless your doctor advises you to stop. Remember that it works to slow the decline in lung function only for as long as you keep taking it. If you stop taking NINDEV 100MG SOFT GELATIN CAPSULE suddenly it worsens the lung function and increases the risk of life-threatening complications.
What are the common side effects of NINDEV 100MG SOFT GELATIN CAPSULE?
The common side effects of taking NINDEV 100MG SOFT GELATIN CAPSULE are diarrhoea, nausea, vomiting, stomach pain, loss of appetite, headache, weight loss, altered liver enzymes and high blood pressure. Consult your doctor if any of the side effect worsens.
Is NINDEV 100MG SOFT GELATIN CAPSULE safe to use in patients with liver disease?
NINDEV 100MG SOFT GELATIN CAPSULE should be taken with caution in patients with liver problems. Your doctor may monitor your liver function before and during management with NINDEV 100MG SOFT GELATIN CAPSULE to assess the risk of liver damage or any unusual effects. Consult your doctor before taking NINDEV 100MG SOFT GELATIN CAPSULE.
Article Information
Written By
DETAILS Written By Dr. R. Dinesh John Rajkumar
Medical Content Writer
Reviewed By
Dr. Sankara Babu Gorle
Medical Expert
Last Updated
20 Mar 2023