Nexpro IT Capsule 10'S
Key Information
Generic Name
Generic Name Esomeprazole 40 mg+Itopride 150 mg
Manufacturer
Torrent Pharmaceuticals Ltd
Variant
10 Capsule(s) in a Strip
Country of Origin
India
Detailed Information
Introduction
INTRODUCTION ABOUT NEXPRO IT CAPSULENEXPRO IT CAPSULE is a combination of Esomeprazole and Itopride which belongs to the group of medicines called Proton pump inhibitors and Gastroprokinetic agents respectively. It is used to manage Gastroesophageal reflux disease (GERD) in patients who does not respond to esomeprazole alone. Gastroesophageal reflux disease (GERD) occurs when stomach contents flow backwards and cause troublesome symptoms or complications like heartburn, excessive salivation, burping, and regurgitation. Though it is primarily a motility problem, acidity of gastric contents is the most important aggressive factor in causing symptoms and lesions in food-pipe. Before taking NEXPRO IT CAPSULE, inform your doctor if you have severe kidney, liver or skin problems, osteoporosis, or about to take any blood tests. NEXPRO IT CAPSULE should be used with caution in pregnant women and it is not recommended for use in breastfeeding women. NEXPRO IT CAPSULE should be used with caution in children and adolescents (under 12 years of age) and elderly patients. The most common
Uses
OF NEXPRO IT CAPSULE Used to manage gastroesophageal reflux disease (GERD) (in patients who does not respond to esomeprazole alone)
How It Works
NEXPRO IT CAPSULE is a combination of Esomeprazole and Itopride, where Esomeprazole suppresses stomach acid secretion by specific blockade of the proton pump at the secretory surface of the stomach cell and Itopride that blocks certain enzyme to increase the stomach motility, lower sphincter pressure of food pipe, stomach emptying and improve the stomach-intestine coordination. This kind of action provides relief from the symptoms of gastroesophageal reflux disease (GERD).
Directions for Use
Take NEXPRO IT CAPSULE as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration of NEXPRO IT CAPSULE for you depending upon your age, body weight and severity of the condition.
Side Effects
taking NEXPRO IT CAPSULE are dizziness, headache, diarrhoea, stomach pain, constipation, flatulence, nausea, vomiting, rash, redness, or itching. Consult your doctor if any of the above side effects worsen. USES OF NEXPRO IT CAPSULE Used to manage gastroesophageal reflux disease (GERD) (in patients who does not respond to esomeprazole alone) HOW NEXPRO IT CAPSULE WORKSNEXPRO IT CAPSULE is a combination of Esomeprazole and Itopride, where Esomeprazole suppresses stomach acid secretion by specific blockade of the proton pump at the secretory surface of the stomach cell and Itopride that blocks certain enzyme to increase the stomach motility, lower sphincter pressure of food pipe, stomach emptying and improve the stomach-intestine coordination. This kind of action provides relief from the symptoms of gastroesophageal reflux disease (GERD). DIRECTIONS FOR USETake NEXPRO IT CAPSULE as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration of NEXPRO IT CAPSULE for you depending upon your age, body weight and severity of the condition. SIDE EFFECTS OF NEXPRO IT CAPSULECOMMON headache dizziness shaking of hands diarrhoea stomach pain constipation flatulence nausea vomiting easy bruising increased milk production excessive development of breasts (male) yellowing of skin and eyes skin rash, redness, and itching UNCOMMON swelling of the feet and ankles difficulty in falling asleep tingling or pricking feeling in nerves excessive sleepiness head spinning sensation (vertigo) dry mouth hip, wrist, or spine fractures (if used in high dose and long duration) RARE weakness, or more chances of infections (signs of reduced white blood cells) weakness, cramps feeling agitated, confused, or depressed taste changes eyesight problems like blurred vision suddenly feeling of wheezing or breathlessness inflammation inside the mouth thrush hair loss joint or muscle pains generally feeling unwell and lacking energy increased sweating Stop taking NEXPRO IT CAPSULE and consult your doctor immediately if you experience any of the following side effects: signs include extreme tiredness, involuntary muscle contractions, disorientation, fits, dizziness or increased heart rate severe allergic reaction (sudden wheezing, swelling of lips, tongue and throat or body, rash, fainting, or trouble swallowing) steven-johnson syndrome or toxic epidermal necrolysis (signs include reddening of the skin with blisters or peeling, severe blisters and bleeding in the lips, eyes, mouth, nose, genitals) signs of liver problems (such as yellow skin, dark urine, or tiredness)
Warnings & Precautions
& PRECAUTIONSPREGNANCYMonitoring requiredNEXPRO IT CAPSULE is not recommended for use in pregnant women unless considered clearly necessary. Consult your doctor before taking NEXPRO IT CAPSULE. BREASTFEEDINGContraindicatedNEXPRO IT CAPSULE is not recommended for use in breastfeeding women. Consult your doctor before taking NEXPRO IT CAPSULE. DRIVING AND USING MACHINESUse with CautionDo not drive or use any machines if you feel dizzy or your vision becomes blurred after taking NEXPRO IT CAPSULE. KIDNEYUse with CautionNEXPRO IT CAPSULE should be used with caution in patients with severe kidney problems. Consult your doctor before taking NEXPRO IT CAPSULE. LIVERUse with CautionNEXPRO IT CAPSULE should be used with caution in patients with severe liver problems. Consult your doctor before taking NEXPRO IT CAPSULE. ALLERGYContraindicatedDo not take NEXPRO IT CAPSULE if you are allergic to Esomeprazole or Itopride or any other ingredients of this medicine. USE IN PEDIATRICSUse with CautionNEXPRO IT CAPSULE should be used with caution in children and adolescents (below 12 years of age) as safety may vary. Consult child’s doctor for advice. USE IN GERIATRICSUse with CautionNEXPRO IT CAPSULE should be used with caution in elderly patients, therefore consult your doctor before taking it. If you observe weight loss for no reason, stomach pain or indigestion, vomiting food or blood, passing black stools (blood-stained faeces) and skin rash on exposure to sunlight while taking NEXPRO IT CAPSULE, consult your doctor immediately. OTHERSNEXPRO IT CAPSULE is not recommended for use if you: have gastrointestinal bleeding, mechanical obstruction, or perforation Before taking NEXPRO IT CAPSULE inform your doctor if you: are scheduled for chromogranin A (CgA) blood test (tumor marker) have osteoporosis (weak bones)
Drug Interactions
SA. Drug-Drug interactions: Before taking NEXPRO IT CAPSULE, inform your doctor if you are taking any of the following medicines: nelfinavir, atazanavir (used to manage HIV infection) clopidogrel, warfarin (used to manage blood clots) medicines used to manage fungal infections (Ex. ketoconazole, itraconazole, voriconazole) medicines used in cancer (Ex. erlotinib, methotrexate) medicines used to manage depression (Ex. citalopram, imipramine, clomipramine, St. John’s wort) diazepam (used to manage anxiety, fits, or to relax muscles) phenytoin (used to manage fits) cilostazol (used to manage intermittent claudication) cisapride (used to manage indigestion and heartburn) digoxin (used to manage heart problems) medicines used to manage a variety of conditions, from overactive bladder to chronic obstructive pulmonary disorder (Ex. atropine, dicyclomine) tacrolimus (used to prevent organ rejection after transplant) rifampicin (used to manage tuberculosis) other medicines used to reduce acidity (Ex. pantoprazole, lansoprazole, rabeprazole and omeprazole) Overdosage: If you or anyone else accidentally take too much of NEXPRO IT CAPSULE, consult your doctor immediately or visit the nearby hospital. SYNOPSIS Drug : Esomeprazole, Itopride Pharmacological Category : Proton pump inhibitor, Prokinetic benzamide derivative Therapeutic Indication : Gastroesophageal reflux disease (GERD) Dosage Forms : Tablet, Capsule MORE INFORMATIONSTORAGE Keep NEXPRO IT CAPSULE out of reach of children Store at room temperature
Frequently Asked Questions
Common questions and answers about Nexpro IT Capsule 10'S.
Can I take NEXPRO IT CAPSULE for a long period of time?
Your doctor will decide the correct duration of NEXPRO IT CAPSULE for you depending upon your age, body weight and severity of the condition. If you need to take it for a long time (especially for more than a year), you may require regular monitoring as it may increase your risk of getting hip, wrist, or spine fractures if used for a long time in high doses. Consult your doctor before taking it for a longer time than prescribed.
Does NEXPRO IT CAPSULE cause photosensitivity reactions?
NEXPRO IT CAPSULE may cause rashes in the skin areas exposed to sunlight. Consult your doctor immediately if it happens and ask about precautionary measures that you can take.
Is NEXPRO IT CAPSULE safe to use during pregnancy?
If you are pregnant, think you may be pregnant or planning to get pregnant, consult your doctor before taking NEXPRO IT CAPSULE. Your doctor will decide whether you can take NEXPRO IT CAPSULE during pregnancy.
Can NEXPRO IT CAPSULE be used in children?
NEXPRO IT CAPSULE should be used with caution in children and adolescents (below 12 years of age) as safety may vary. Your doctor will decide the correct dose or select a suitable alternative therapy for your child to manage the condition.
What if I forget to take a dose of NEXPRO IT CAPSULE?
If you forget to take a dose of NEXPRO IT CAPSULE, take it as soon as you remember. However, omit the missed dose if it is almost time for the next dose. Do not take NEXPRO IT CAPSULE twice to make up for a forgotten dose.
Article Information
Written By
DETAILS Written By Dr. Janet.C
Medical Content Writer
Reviewed By
Dr. Sankara Babu Gorle
Medical Expert
Last Updated
23 Sep 2024