NEVIR ER Tablet 30's
Key Information
Generic Name
Generic Name Nevirapine 400 mg
Manufacturer
Emcure Pharmaceuticals Ltd
Variant
30 Tablet(s) in a Strip
Country of Origin
India
Detailed Information
Introduction
NEVIR ER TABLET contains Nevirapine which belongs to the group of medicines called Antiretroviral drugs. It indicated for the management of Human Immunodeficiency Virus (HIV) infection in combination with other anti-retroviral medicines in adults, adolescents and children. HIV is a virus which severely damages the immune system and leads to Acquired Immune Deficiency Syndrome (AIDS) which is characterized by fever, chills, rash, night sweat, muscle aches, sore throat, fatigue. During management, your doctor will advise you to take certain blood tests to monitor your liver function. NEVIR ER TABLET should be used with caution in patients having inflammation of liver (hepatitis B or C) or abnormal liver function tests. Before taking NEVIR ER TABLET, inform your doctor if are undergoing kidney dialysis or have any heart disease. NEVIR ER TABLET should be used with caution in pregnant woman and is not intended for use in breastfeeding women. Your doctor will prescribe the right dose of NEVIR ER TABLET for your child depending on their age, body weight and body surface area. The most common
Uses
OF NEVIR ER TABLET Used in adults, adolescents and children to manage Human Immunodeficiency Virus (HIV) infection in combination with other anti-retroviral medicines
How It Works
NEVIR ER TABLET helps control HIV-1 infection by stopping reverse transcriptase (an enzyme needed by HIV in order to multiply) from working.
Directions for Use
Take NEVIR ER TABLET as advised by your physician. Swallow with a glass of water, do not crush or chew it. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition. Do not stop taking NEVIR ER TABLET unless your doctor advises you to stop.
Side Effects
taking NEVIR ER TABLET are skin rash, headache, fatigue (feeling tired), nausea, vomiting, abdominal pain, diarrhea, fever, etc. USES OF NEVIR ER TABLET Used in adults, adolescents and children to manage Human Immunodeficiency Virus (HIV) infection in combination with other anti-retroviral medicines HOW NEVIR ER TABLET WORKSNEVIR ER TABLET helps control HIV-1 infection by stopping reverse transcriptase (an enzyme needed by HIV in order to multiply) from working. DIRECTIONS FOR USETake NEVIR ER TABLET as advised by your physician. Swallow with a glass of water, do not crush or chew it. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition. Do not stop taking NEVIR ER TABLET unless your doctor advises you to stop. SIDE EFFECTS OF NEVIR ER TABLETCOMMON skin rash decreased numbers of white blood cells which makes you more prone to infection headache, fatigue (feeling tired) nausea, vomiting, stomach pain, diarrhoea signs of inflammation of the liver (hepatitis) like jaundice, nausea, dark urine, light coloured stools, abdominal pain fever UNCOMMON angioedema (fluid retention under the skin), hives anaemia (decreased red blood cells count) joint or muscle pain high blood pressure RARE signs of sudden and intense inflammation of the liver or fulminant hepatitis like swollen belly, upper right abdomen pain, vomiting, etc drug reaction with systemic symptoms (drug reaction with increased eosinophil count or eosinophilia) Stop taking NEVIR ER TABLET and contact your doctor immediately if you experience any of the following side effects: symptoms of infection muscle weakness, weakness beginning in the hands and feet and moving upwards the trunk of the body, throbbing sensation, shakiness or hyperactivity changes in body fat osteonecrosis (a bone disorder causing joint stiffness, aches and pains especially of the hip, knee and shoulder and difficulty in movement) rash that appears as blistering skin reaction, which can be severe or life-threatening (Ex. toxic epidermal necrolysis, Stevens-Johnson syndrome) symptoms of severe allergic or anaphylactic reaction like rash, swelling of face, breathing difficulty, anaphylactic shock, fever, skin blisters, mouth sores, eye inflammation, muscle or joint pain, feeling unwell, liver or kidney failure liver damage (loss of appetite, nausea, vomiting, yellow skin, abdominal pain)
Warnings & Precautions
& PRECAUTIONSPREGNANCYNEVIR ER TABLET should be used with caution in woman who are pregnant or planning to become pregnant. Women should use effective contraception methods during management with NEVIR ER TABLET. Consult your doctor before taking it. BREASTFEEDINGNEVIR ER TABLET is not recommended for use in breastfeeding women as your baby may become infected with HIV through breastmilk. Consult your doctor before taking it. DRIVING AND USING MACHINESDo not drive or operate any machines if you feel extremely tired after taking NEVIR ER TABLET. ALCOHOLAvoid consumption of alcohol while taking NEVIR ER TABLET as it may increase the risk of bone problems. KIDNEYNEVIR ER TABLET should be taken with caution in patients undergoing kidney dialysis. Consult your doctor before taking it. LIVERNEVIR ER TABLET should be used with caution in patients having inflammation of liver (hepatitis B or C) or abnormal liver function tests. Consult your doctor before taking it. ALLERGYDo not take NEVIR ER TABLET if you are allergic to Nevirapine or any of the other ingredients of this medicine. HEART DISEASENEVIR ER TABLET should be taken with caution in patients having heart disease. Consult your doctor before taking it. OTHERSNEVIR ER TABLET is not recommended for use if you: have previously discontinued management with nevirapine due to severe skin rashes or liver problems Use in Pediatrics: Your doctor will prescribe the right dose of NEVIR ER TABLET for your child depending on their age, body weight and body surface area. Consult your child’s doctor for advice. Use in Geriatrics: NEVIR ER TABLET should be used with caution in elderly patients (aged above 65 years). Consult your doctor before taking it.
Drug Interactions
SA. Drug - Drug interactions: Before taking NEVIR ER TABLET, inform your doctor if you are taking any of the following medicines: St. John’s Wort (herbal medicine used for depression) rifampicin, rifabutin (used to manage tuberculosis) clarithromycin (used to manage bacterial infections) fluconazole, ketoconazole, itraconazole (medicines used to manage fungal infections) methadone (medicine used in management of opiate addicts) warfarin (used to reduce clotting of blood) medicines used to manage pregnancy (Ex. ethinyl estradiol, progestin) atazanavir, lopinavir, ritonavir, fosamprenavir, efavirenz, etravirine, zidovudine, elvitegravir, cobicistat, rilpivirine (other medicines used to manage HIV-infection) Overdosage: If you or anyone else accidentally take too much of NEVIR ER TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of NEVIR ER TABLET overdose include swelling, redness, tiredness, fever, headache, sleep problems, nausea, rash, spinning sensation, vomiting and weight loss. SYNOPSIS Drug : Nevirapine Pharmacological Category : Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTIs) Therapeutic Indication : HIV infection Dosage Forms : Tablet, Oral suspension, Suspension MORE INFORMATION Keep NEVIR ER TABLET out of reach of children Store at room temperature
Article Information
Written By
DETAILS Written By Dr. Jeenal Rajani
Medical Content Writer
Reviewed By
Dr. Sankara Babu Gorle
Medical Expert
Last Updated
10 Dec 2022