Neurokem Plus Capsule 10'S
Key Information
Generic Name
Generic Name Alpha Lipoic Acid 100 mg+Folic Acid 1.5 mg+Methylcobalamin 750 mcg+Pregabalin 75 mg+Pyridoxine 3 mg
Manufacturer
Alkem Laboratories Ltd
Variant
10 Capsule(s) in a Strip
Country of Origin
India
Detailed Information
Introduction
INTRODUCTION ABOUT NEUROKEM PLUS CAPSULENEUROKEM PLUS CAPSULE is a combination of Alpha lipoic acid, Methylcobalamin, Folic acid, Pregabalin, and Pyridoxine, which belong to the group of medicines called Antioxidants, Cyclic GABA analogues, and Vitamin B complexes, respectively. It is used in adults to manage painful diabetic neuropathy (nerve damage occurring over time because of high sugar and fat levels in the blood due to diabetes). The symptoms depend on the type of neuropathy, such as pain and numbness in your feet or problems with organ functions like those of your heart and bladder. Avoid consuming alcohol during management with GBNKEYWORD. NEUROKEM PLUS CAPSULE is not recommended for use in children and adolescents (younger than 18 years), so consult your doctor before taking it. Before taking NEUROKEM PLUS CAPSULE, inform your doctor if you have any kidney, liver, heart, respiratory, or nervous system problems; diabetes; or a history of alcoholism or any drug abuse or dependence. NEUROKEM PLUS CAPSULE should not be used in pregnant or breastfeeding women unless necessary. The most common
Uses
OF NEUROKEM PLUS CAPSULE Manage painful diabetic neuropathy in adults.
How It Works
NEUROKEM PLUS CAPSULE relieves nerve pain where alpha-lipoic acid reduces oxidative stress, which is con
Directions for Use
Take NEUROKEM PLUS CAPSULE as advised by your physician. Swallow it with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration of NEUROKEM PLUS CAPSULE for you based on your age, body weight, and disease condition. Do not stop taking NEUROKEM PLUS CAPSULE unless your doctor advises you to stop.
Side Effects
taking NEUROKEM PLUS CAPSULE are dizziness, drowsiness, headache, increased appetite, blurred vision, weight gain, etc. Contact your doctor if any of the symptoms get worse. USES OF NEUROKEM PLUS CAPSULE Manage painful diabetic neuropathy in adults. HOW NEUROKEM PLUS CAPSULE WORKSNEUROKEM PLUS CAPSULE relieves nerve pain where alpha-lipoic acid reduces oxidative stress, which is considered a main pathophysiology of diabetic neuropathy development; folic acid (Vitamin B9) is found to improve the functional recovery of nerves, speed of nerve conduction, and cell multiplication; and methylcobalamin takes part in the production of myelin (a compound that covers and protects nerve fibers), thus restoring the damaged nerve cell. Pregabalin binds with high affinity to certain sites in the tissues of the central nervous system and acts as a growth factor for nerve cells, helping to regenerate the damaged nerve tissue, and pyridoxine acts as a coenzyme in a wide range of metabolic functions affecting protein, carbohydrate, and lipid utilization, like the breakdown of glycogen to glucose-1-phosphate and the synthesis of gamma-aminobutyric acid (GABA). DIRECTIONS FOR USETake NEUROKEM PLUS CAPSULE as advised by your physician. Swallow it with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration of NEUROKEM PLUS CAPSULE for you based on your age, body weight, and disease condition. Do not stop taking NEUROKEM PLUS CAPSULE unless your doctor advises you to stop. SIDE EFFECTS OF NEUROKEM PLUS CAPSULECOMMON Dizziness, drowsiness, headache Feeling elated, confused, or disorientated Decreased sexual interest, irritability Disturbed attention, clumsiness, memory impairment or loss, shaking, trouble speaking, tingling feeling, numbness, sedation, lethargy, lack of sleep, fatigue, feeling weird Double vision Spinning sensation, problems with balance, fall Increased appetite, dry mouth, constipation, vomiting, gas, diarrhea, nausea, and a swollen abdomen Difficulties with erections Swollen body, including extremities Feeling drunk, abnormal walking style Weight gain Muscle cramp, joint, back, or limb pain Sore throat UNCOMMON Loss of appetite and weight Low or high blood sugar Change in self-perception, agitation, mood swings, restlessness, depression, difficulty finding words Seeing things that are not there, unusual dreams, panic attacks, lack of interest, aggression, and elevated mood Mental impairment, trouble thinking, increased sexual interest, sexual problems including the inability to achieve a sexual climax, delayed ejaculation Changes in eyesight, unusual eye movement, tunnel vision, flashes of light Jerky movements, reduced reflexes, increased activity, dizziness while standing, and skin sensitivity Taste loss, burning sensation, shaking on movement, low or loss of consciousness, increased noise sensitivity, feeling unwell Eye swelling, pain, weakness, watering, irritation, or dryness Heart rhythm changes, increased heart rate, low or high blood pressure, changes in heartbeat, heart failure Flushing and hot flushes Nasal dryness or congestion Increased salivation, heartburn, and numbness around the mouth Sweating, rash, chills, and fever Muscle twitching, swollen joints, stiff muscles, or neck pain Breast pain Troubled or painful urination, incontinence Weakness, thirst, and chest tightness Changes in blood and liver test results (high blood creatinine phosphokinase, alanine aminotransferase, aspartate aminotransferase, blood creatinine, low platelet count, neutrophils, and blood potassium) Hypersensitivity, swollen face, itchiness, hives, cough, snoring, runny nose, nosebleed Painful menstrual periods Cold hands and feet RARE Abnormal sense of smell, swinging vision, changed perception of depth, visual brightness, vision loss Dilated pupils, cross eyes Cold sweat, throat tightness Pancreatic inflammation Trouble swallowing Slow or decreased body movement Trouble writing properly Increased abdominal fluid Fluid in the lungs Muscle damage Breast discharge, unusual breast growth, and breast enlargement in men Interrupted menstrual periods Decreased white blood cell count Inappropriate behaviour Allergic reactions (trouble breathing, eye inflammation, a serious skin reaction characterized by rash, blisters, peeling skin, and pain) Jaundice (yellow skin and eyes) Stop taking NEUROKEM PLUS CAPSULE and contact your doctor immediately if you experience any of the following side effects: Swollen face Skin turning red and starting to blister or peel Allergic reaction (swelling of the face, lips, tongue, and throat; diffuse skin rash) Blurring, loss of eyesight, or other changes in vision Kidney failure, reduced urine volume Thoughts of harming or killing oneself Constipation Fits Trouble breathing or shallow breaths
Warnings & Precautions
& PRECAUTIONSPREGNANCYMonitoring requiredNEUROKEM PLUS CAPSULE is not recommended for use by pregnant women unless considered necessary. Females of childbearing capability must use effective contraception. Consult your doctor before taking it. BREASTFEEDINGMonitoring requiredNEUROKEM PLUS CAPSULE is not recommended for use by breastfeeding women unless considered necessary. Consult your doctor before taking it. DRIVING AND USING MACHINESContraindicatedDo not drive or operate any machines if you experience dizziness, sleepiness, or decreased concentration after taking NEUROKEM PLUS CAPSULE. ALCOHOLContraindicatedAvoid consumption of alcohol while taking NEUROKEM PLUS CAPSULE. Let your doctor know if you have a history of alcoholism. KIDNEYUse with CautionNEUROKEM PLUS CAPSULE should be taken with caution in patients with kidney disease or impairment. Consult your doctor before taking it. LIVERUse with CautionNEUROKEM PLUS CAPSULE should be taken with caution in patients with liver disease. Consult your doctor before taking it. ALLERGYContraindicatedDo not take NEUROKEM PLUS CAPSULE if you are allergic to alpha-lipoic acid, methylcobalamin, folic acid, pregabalin, pyridoxine, or any of the other ingredients of NEUROKEM PLUS CAPSULE. LUNGSUse with CautionNEUROKEM PLUS CAPSULE should be taken with caution in patients with respiratory disorders. Consult your doctor before taking it. HEART DISEASEUse with CautionNEUROKEM PLUS CAPSULE should be taken with caution in patients with a history of heart disease or who received a coronary stent (a tube inserted in the artery that leads to the heart, to manage blockages). Consult your doctor before taking it. USE IN PEDIATRICSContraindicatedNEUROKEM PLUS CAPSULE is not recommended for use in children and adolescents (under 18 years of age). Consult your doctor before taking it. USE IN GERIATRICSUse with CautionNEUROKEM PLUS CAPSULE should be used with caution in elderly patients (aged above 75 years) with kidney problems and the elderly in general, as it causes dizziness and sleepiness, which could increase the occurrence of accidental injury (fall) in them. Consult your doctor before taking it. OTHERSBefore taking NEUROKEM PLUS CAPSULE, inform your doctor if you: Have diabetes (high blood sugar) Are prone to constipation Have a history of any drug abuse or dependence Have nervous system disorders Have a folate-dependent tumour
Drug Interactions
SA. Drug-Drug interactions: Before taking NEUROKEM PLUS CAPSULE, inform your doctor if you are taking any of the following medicines: Oxycodone (used to manage severe pain) Lorazepam (used to manage anxiety) Medicines containing alcohol Overdosage: If you or anyone else accidentally took too much of NEUROKEM PLUS CAPSULE, contact your doctor immediately. Symptoms of NEUROKEM PLUS CAPSULE overdose are sleepiness, confusion, agitation, restlessness, or fits. SYNOPSIS Drug : Alpha Lipoic Acid, Methylcobalamin, Folic Acid, Pyridoxine, and Pregabalin Pharmacological Category : Antioxidants, Vitamins, and Cyclic GABA Analogues Therapeutic Indication : Painful diabetic neuropathy Dosage Forms : Tablet, Capsule MORE INFORMATIONSTORAGE Keep NEUROKEM PLUS CAPSULE out of reach of children Store NEUROKEM PLUS CAPSULE below 25°C
Frequently Asked Questions
Common questions and answers about Neurokem Plus Capsule 10'S.
Can I take NEUROKEM PLUS CAPSULE if I have diabetes?
Before taking NEUROKEM PLUS CAPSULE, inform your doctor if you have diabetes and about the medicines you are taking for it, as according to current clinical practice, some diabetic patients who gain weight on NEUROKEM PLUS CAPSULE management may need to adjust the doses of their anti-diabetic medicines.
Can NEUROKEM PLUS CAPSULE make me feel suicidal?
Thoughts of harming or killing oneself are seen in a small number of patients being managed with NEUROKEM PLUS CAPSULE. If at any time you have such thoughts, immediately contact your doctor or go to the nearest hospital.
Can NEUROKEM PLUS CAPSULE be taken during pregnancy?
NEUROKEM PLUS CAPSULE should not be used in pregnant women unless necessary. Females who are of childbearing age must use effective contraception. If you are pregnant, think you may be pregnant, or are planning to get pregnant, consult your doctor before taking NEUROKEM PLUS CAPSULE. Inform your doctor immediately if you become pregnant during management with NEUROKEM PLUS CAPSULE.
Can NEUROKEM PLUS CAPSULE cause constipation?
NEUROKEM PLUS CAPSULE may cause constipation and other gastrointestinal problems like blocked or paralyzed intestines when taken with other medicines (like some types of pain medicines). In such cases, eat plenty of fiber-rich foods, such as fresh fruits, vegetables, and cereals, and drink plenty of water. Inform your doctor if you feel constipated, especially if you are prone to this problem.
Can I drink alcohol during management with NEUROKEM PLUS CAPSULE?
Avoid drinking alcohol during management with NEUROKEM PLUS CAPSULE and inform your doctor if you have a history of alcoholism.
Can NEUROKEM PLUS CAPSULE be given to children?
No. NEUROKEM PLUS CAPSULE is used for adults and not recommended for children and adolescents below 18 years of age, as the safety and efficacy of NEUROKEM PLUS CAPSULE in this age group have not been established. Your doctor will select a suitable alternative management plan for your child.
Can I take NEUROKEM PLUS CAPSULE on an empty stomach?
Take NEUROKEM PLUS CAPSULE as advised by your physician. You take it with or without food. However, if you feel nauseous, take NEUROKEM PLUS CAPSULE with meals or just after meals.
What if I forget to take a dose of NEUROKEM PLUS CAPSULE?
If you forget to take a dose of NEUROKEM PLUS CAPSULE, take it as soon as you remember. However, omit the missed dose if it is almost time for the next one. Do not take NEUROKEM PLUS CAPSULE twice to make up for the missed dose.
Can I stop taking NEUROKEM PLUS CAPSULE on my own?
Continue taking NEUROKEM PLUS CAPSULE until your doctor tells you to stop, unless you experience any unwanted effects, a worsening of your condition, or any new symptoms. In such a case, contact your doctor. Your doctor will advise you to stop taking NEUROKEM PLUS CAPSULE gradually over a period of at least one week.
Can NEUROKEM PLUS CAPSULE discontinuation cause withdrawal symptoms?
After stopping NEUROKEM PLUS CAPSULE management, you may experience certain side effects like trouble sleeping, headache, nausea, anxiety, diarrhea, flu-like symptoms, fits, nervousness, depression, pain, sweating, and dizziness. There are more chances of getting these symptoms if you have been taking this medicine for a longer period of time. If you have any further doubts regarding the use of NEUROKEM PLUS CAPSULE, ask your doctor.
How should NEUROKEM PLUS CAPSULE be taken? Can it be crushed?
No. Do not break, crush, or chew NEUROKEM PLUS CAPSULE. Take it as advised by your physician. Swallow it with a glass of water. Your doctor will determine the correct dose and duration for you based on your age, body weight, and disease condition.
Article Information
Written By
DETAILS Written By Dr. N. Sai Swaroop
Medical Content Writer
Reviewed By
Dr. Sankara Babu Gorle
Medical Expert
Last Updated
10 Jul 2024