NEOCLOVIR 500 Infusion 20ml
Key Information
Generic Name
Generic Name Acyclovir 25 mg Also Known As: Aciclovir
Manufacturer
Neon Laboratories Ltd
Country of Origin
India
Detailed Information
Introduction
INTRODUCTION ABOUT NEOCLOVIR 500 INFUSIONNEOCLOVIR 500 INFUSION contains Acyclovir, which belongs to the group of medicines called Antivirals. It is used for the management of varicella zoster infections (an infection caused by the varicella-zoster virus and symptoms include an itchy rash with small, fluid-filled blisters) and herpes encephalitis caused by the Herpes Simplex Virus in neonates and adults. Symptoms include headaches, fevers, drowsiness, hyperactivity and general weakness). Herpes simplex infections and severe initial genital herpes (a common sexually transmitted infection caused by the herpes simplex virus) in patients with a weakened immune system, prophylaxis of Herpes simplex infections in immunodeficient patients and management of Herpes simplex infections in the neonates and infants up to three months of age. Before receiving NEOCLOVIR 500 INFUSION inform your doctor if you have kidney problems. NEOCLOVIR 500 INFUSION should be used with caution among pregnant or breastfeeding women, therefore consult your doctor before receiving it. The most common
Uses
OF NEOCLOVIR 500 INFUSION Manage and manages herpes infections Manage chickenpox and shingles
How It Works
NEOCLOVIR 500 INFUSION works by killing or stopping the growth of viruses (herpes virus). It has a higher affinity for viral DNA cells than human DNA cells and incorporates into the viral DNA and causes DNA chain termination and inactivation, leading to the death of cells.
Directions for Use
NEOCLOVIR 500 INFUSION will be given to you only by a doctor or a nurse into a vein as an intravenous infusion. Your doctor will decide the correct dose and duration for you depending on your age, body weight and disease condition.
Side Effects
NEOCLOVIR 500 INFUSION Manage and manages herpes infections Manage chickenpox and shingles HOW NEOCLOVIR 500 INFUSION WORKSNEOCLOVIR 500 INFUSION works by killing or stopping the growth of viruses (herpes virus). It has a higher affinity for viral DNA cells than human DNA cells and incorporates into the viral DNA and causes DNA chain termination and inactivation, leading to the death of cells. DIRECTIONS FOR USENEOCLOVIR 500 INFUSION will be given to you only by a doctor or a nurse into a vein as an intravenous infusion. Your doctor will decide the correct dose and duration for you depending on your age, body weight and disease condition. SIDE EFFECTS OF NEOCLOVIR 500 INFUSIONCOMMON nausea and vomiting allergic reactions such as rashes, itchy, sensitivity to light swelling, redness, tenderness or pain at the site of injection elevated liver enzymes increase in blood urea and creatinine UNCOMMON anaemia, leukopenia, thrombocytopenia rashes include photosensitivity, urticaria, pruritus nosebleeds and bruises easily due to a decrease in blood platelets fatigue, decreased energy, weakness, dyspnoea (shortness of breath), fainting, palpitations, pale skin due to anaemia risk of infections due to falling in white blood cells RAREStop taking NEOCLOVIR 500 INFUSION and contact your doctor immediately if you experience any of the following side effects: severe allergic reactions such as erythema multiforme, photosensitive rash, pruritus, rash, Stevens-Johnson syndrome, toxic epidermal necrolysis, urticaria and tissue necrosis encephalopathy changes characterized by lethargy, obtundation, tremors, confusion, hallucinations, agitation, seizures or coma signs of liver problems such as hepatitis, hyperbilirubinemia, jaundice (yellowing of the skin and the whites of the eyes)
Warnings & Precautions
& PRECAUTIONSPREGNANCYNEOCLOVIR 500 INFUSION is generally not recommended for use in pregnant women unless considered necessary. Consult your doctor before receiving NEOCLOVIR 500 INFUSION. BREASTFEEDINGNEOCLOVIR 500 INFUSION is not recommended for use in breastfeeding women as it may pass through the breast milk. Consult your doctor before receiving NEOCLOVIR 500 INFUSION. DRIVING AND USING MACHINESDo not drive or operate any machines if you have confusion, hallucinations, agitation, tremors and drowsiness after receiving NEOCLOVIR 500 INFUSION. KIDNEYNEOCLOVIR 500 INFUSION should be used with caution in patients with kidney diseases. Consult your doctor before receiving NEOCLOVIR 500 INFUSION. ALLERGYDo not receive NEOCLOVIR 500 INFUSION if you are allergic to Acyclovir or valacyclovir or any other ingredients of this medicine. OTHERSBefore receiving NEOCLOVIR 500 INFUSION, inform your doctor: if you have a low resistance to disease (immune deficiency) dehydration low sodium diet Use in pediatrics: NA Use in geriatrics: NEOCLOVIR 500 INFUSION should be used with caution in elderly patients (aged above 75 years). Consult your doctor before receiving it.
Drug Interactions
SA. Drug-Drug interactions: Before receiving NEOCLOVIR 500 INFUSION, inform your doctor if you are taking any of the following medicine: probenecid (a medicine used to manage gout) cimetidine (a medicine used to manage stomach ulcers) drugs acting on the immune system (Ex. mycophenolate mofetil, cyclosporine and tacrolimus) lithium (a medicine used to manage bipolar disorder) theophylline (a medicine used to manage breathing disorders) B. Drug - Food interaction: NA Overdosage: NEOCLOVIR 500 INFUSION will be administered to you only by a doctor or a nurse in a hospital, so it is unlikely to receive an overdose. However, consult your doctor or nurse if you experience any unusual symptoms. SYNOPSIS Drug : Acyclovir Pharmacological Category : Antivirals Therapeutic Indication : Chickenpox, shingles, herpes simplex virus Dosage Forms : Tablet, Suspension, Syrup, Infusion, Injection, Cream, Ointment, Eye- ointment MORE INFORMATION Keep NEOCLOVIR 500 INFUSION out of the sight and reach from children Store NEOCLOVIR 500 INFUSION below 25°C
Article Information
Written By
ity (HPRA). [Revised on January 2021] [Accessed on 19th April 2022] https://www.hpra.ie/img/uploaded/swedocuments/994b7cee-33e9-4b21-9d05-e61b866df4f1.pdf 6. Hospira UK Limited. Electronic Medicines Compendium (EMC). [Revised in August 2021] [Accessed on 19th April 2022] USEFUL DIAGNOSTIC TESTS Herpes Simplex Virus 1 DNA PCR Herpes Simplex Virus 1 IgG Herpes Simplex Virus 2 DNA PCR Herpes Simplex Virus 2 IgG Herpes Simplex Virus 2 IgM Varicella Zoster IgG Varicella Zoster IgM AUTHOR DETAILS Written By Dr. Dhivakaran R
Medical Content Writer
Reviewed By
Dr. Sankara Babu Gorle
Medical Expert
Last Updated
19 Oct 2022