Methergin Tablet 10'S
Key Information
Generic Name
Generic Name Methylergometrine 0.125 mg
Manufacturer
Dr. Reddy's Laboratories Ltd
Variant
10 Tablet(s) in a Strip
Country of Origin
India
Detailed Information
Introduction
METHERGIN TABLET contains Methylergometrine which belongs to a group of medicines called Ergot alkaloids. METHERGIN TABLET is used in the routine management of uterine atony (inability of the uterus to contract sufficiently during and after childbirth), haemorrhage and subinvolution of the uterus (delayed return of enlarged uterus to normal size) following delivery of placenta. METHERGIN TABLET is also used to control uterine haemorrhage (heavy/unusual bleeding from uterus) following delivery of anterior shoulder of the foetus (childbirth). METHERGIN TABLET is not recommended for use in patients allergic to Methylergometrine. It is also not recommended for use in patients with high blood pressure, and/or toxemia (blood poisoning due to local bacterial infection). Before taking METHERGIN TABLET, inform your doctor if you are a smoker, and/or have high cholesterol, obesity, diabetes, heart problems (such as coronary artery disease), kidney problems (such as impaired renal function), and/or liver problems (such as impaired hepatic function). METHERGIN TABLET is generally not recommended for use during pregnancy and in breast feeding women. The medicine should be taken with caution in elderly women (aged above 65 years) after consulting the doctor. The most common
Uses
OF METHERGIN TABLET Helps in the routine management of uterine atony, haemorrhage and subinvolution of the uterus following delivery of placenta Helps to control uterine haemorrhage following delivery of anterior shoulder of the foetus (childbirth)
How It Works
METHERGIN TABLET works by causing sustained contractions of uterine smooth muscles by acting directly on the uterine smooth muscle which leads to compression of blood vessels resulting in controlled/reduced blood loss following childbirth.
Directions for Use
Take METHERGIN TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
Side Effects
METHERGIN TABLETCOMMON hypertension associated with seizure, and/or headache RARE chest pain, fast/rapid/slow heart rate, coronary arterial spasm (sudden tightening of arteries of heart), heart attack vasoconstriction, vasospasm (narrowing of brain blood vessel) shortness of breath hematuria (blood in urine) thrombophlebitis (inflammation of a vein) hallucinations, dizziness leg cramps, ringing in ears, nasal congestion diarrhoea diaphoresis (sweating at a usual degree) rash foul taste signs of anaphylaxis reaction (life threatening allergic reaction) such as red itchy welts, low blood pressure, wheezing, and/or trouble in breathing
Warnings & Precautions
& PRECAUTIONSPREGNANCYMETHERGIN TABLET is generally not recommended for use during pregnancy. Consult your doctor before taking METHERGIN TABLET. BREASTFEEDINGMETHERGIN TABLET is generally not recommended for use in breast feeding women since the medicine may pass through breast milk. Consult your doctor before taking METHERGIN TABLET. KIDNEYMETHERGIN TABLET should be used with caution in patients with kidney problems such as impaired renal function. Consult your doctor before taking the medicine. LIVERMETHERGIN TABLET should be used with caution in patients with liver problems such as impaired hepatic function. Consult your doctor before taking the medicine. ALLERGYDo not take METHERGIN TABLET if you are allergic to Methylergometrine, and/or any other ingredients of this medicine. HEART DISEASEMETHERGIN TABLET should be used with caution in patients with heart problems such as coronary artery disease. Consult your doctor before taking the medicine. OTHERSMETHERGIN TABLET is not recommended for use if you: have high blood pressure suffer from toxemia (blood poisoning due to local bacterial infection) Before taking METHERGIN TABLET, inform your doctor if you: are a smoker suffer from high cholesterol, obesity, diabetes have obliterative vascular disease (gradual narrowing of arterial blood vessel), and/or suffer from sepsis (life threatening complication of an infection) are in second stage of labor Use in Geriatrics: METHERGIN TABLET should be used with caution in elderly patients (aged 65 years and above). Consult your doctor before taking the medicine.
Drug Interactions
SA. Drug-Drug interactions: Before taking METHERGIN TABLET, inform your doctor if you are taking any of the following medicine: macrolide antibiotics (medicines used to manage bacterial infections) such as erythromycin, troleandomycin, clarithromycin HIV protease/reverse transcriptase inhibitors (medicines used to manage HIV) Ex. atazanavir, cobicistat, darunavir, delavirdine, fosamprenavir, indinavir, nelfinavir, ritonavir, saquinavir, nevirapine nefazodone, fluoxetine, fluvoxamine (medicines used to manage depression) fluconazole, itraconazole, ketoconazole, posaconazole, voriconazole, clotrimazole (medicines used to manage fungal disease) zileuton (used to manage asthma) rifampicin (used to manage infections) beta-blockers (used to manage high blood pressure) Ex. acebutolol, atenolol aesthetics (medicines used for the induction and maintenance of general anaesthesia) Ex. halothan, methoxyfluran glyceryl trinitrate (used to manage angina) prostaglandins (used to induce labor/abortion and manage postpartum haemorrhage) B. Drug-Food interaction: Grapefruit/or its juice may interact with this medicine and lead to unwanted side effects. Consult your doctor before taking any grapefruit products. Overdosage: If you or anyone else accidentally take too much of METHERGIN TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose are nausea, vomiting, oliguria (low urine output), abdominal pain, numbness, tingling of the extremities, rise in blood pressure, low blood pressure, respiratory depression, hypothermia (dangerous drop in body temperature), convulsions, and/or coma. SYNOPSIS Drug : Methylergometrine Pharmacological Category : Ergot alkaloid Therapeutic Indication : Routine management of uterine atony, haemorrhage and subinvolution of the uterus (following delivery of placenta), Control uterine haemorrhage following childbirth Dosage Forms : Tablet, Injection MORE INFORMATION Keep METHERGIN TABLET out of reach of children Do not store METHERGIN TABLET above 30°C
Article Information
Written By
DETAILS Written By Dr. K .AZEEM HUSSAIN
Medical Content Writer
Reviewed By
Dr. Sankara Babu Gorle
Medical Expert
Last Updated
30 Nov 2022