Mesacol Enema 60ml
Key Information
Generic Name
Generic Name Mesalazine 4 gm Also Known As: Mesalamine, 5-Aminosalicylic Acid
Manufacturer
Sun Pharmaceutical Industries Ltd
Country of Origin
India
Detailed Information
Introduction
INTRODUCTION ABOUT MESACOL ENEMAMESACOL ENEMA contains Mesalamine which belongs to the group of medicines called Salicylates. MESACOL ENEMA is used to manage inflammation of gut caused by conditions such as ulcerative colitis which is a type of chronic inflammatory bowel disease that affects last part of colon and rectum (back passage) in affected individuals. MESACOL ENEMA is not recommended for use in patients allergic to Mesalamine, salicylates (such as acetylsalisylic acid), and/or sulphasalazine. It is also not recommended for use in patients with serious kidney and liver disease. Before using [GBKEYWORD], inform your doctor if you have any medical condition that makes you prone to bleed, and/or have lung problems (such as asthma), mild to moderate kidney/liver problems. MESACOL ENEMA should be used with caution in pregnant and breastfeeding women only if it is clearly necessary. It is not recommended for use children and adolescents (aged below 18 years) and is advised to be used with caution in elderly patients (aged above 65 years) after consulting the doctor. The most common
Uses
OF MESACOL ENEMA Manage inflammation of gut caused by conditions such as ulcerative colitis (chronic inflammatory bowel disease) in affected individuals.
How It Works
MESACOL ENEMA works by suppressing the production of prostaglandins (chemical messengers responsible for inflammation in the intestines) which results in reduced inflammation and ulceration thus providing relief from ulcerative colitis (and its associated symptoms) in affected individuals.
Directions for Use
Administer MESACOL ENEMA as advised by your physician. It is for rectal use only. Empty your bowels (if necessary) before use and wash your hands. Shake the bottle for atleast 30 seconds. Remove the protective cap from the applicator and hold the bottle by its upper end. Lie down on your left
Side Effects
using MESACOL ENEMA are abdominal pain, nausea/vomiting, diarrhoea, rash, headache, rectal discomfort, and/or irritation at the site of application. Consult your doctor if any of these symptoms worsens. USES OF MESACOL ENEMA Manage inflammation of gut caused by conditions such as ulcerative colitis (chronic inflammatory bowel disease) in affected individuals. HOW MESACOL ENEMA WORKSMESACOL ENEMA works by suppressing the production of prostaglandins (chemical messengers responsible for inflammation in the intestines) which results in reduced inflammation and ulceration thus providing relief from ulcerative colitis (and its associated symptoms) in affected individuals. DIRECTIONS FOR USEAdminister MESACOL ENEMA as advised by your physician. It is for rectal use only. Empty your bowels (if necessary) before use and wash your hands. Shake the bottle for atleast 30 seconds. Remove the protective cap from the applicator and hold the bottle by its upper end. Lie down on your left side with your left leg outstretched and your right leg bent. Insert the applicator (coated with a lubricant) for easy insertion into the rectum. Hold the bottle pointed towards your navel and squeeze it gently. Remove the applicator from the rectum when the bottle is empty. Maintain this position for at least 30 minutes and allow the medicine to spread throughout the lower part of the large intestine. Wash your hands (after use) and avoid emptying your bowel until next morning. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition. SIDE EFFECTS OF MESACOL ENEMACOMMON abdominal pain, nausea, vomiting, diarrhoea, flatulence headache rash rectal discomfort irritation at the site of application RARE signs of inflammation of heart (myocarditis/pericarditis) such as shortness of breath, chest pain, rapid/irregular heart beats signs of inflammation of the pancreas such as back/stomach pain dizziness photosensitivity (increased sensitivity of your skin to sun and ultraviolet light) Stop taking MESACOL ENEMA and consult your doctor immediately in case you experience: serious skin reactions such as Stevens-Johnson syndrome, toxic epidermal necrolysis associated with symptoms such as reddish non-elevated, target-like/circular patches on the trunk associated with central blisters, skin peeling, ulcers of eyes, nose, mouth, throat, and/or genitals signs of allergic reaction such as difficulty in breathing/wheeziness, itching, skin rashes, and/or swelling of the face/lips/throat signs of blood disorder such as unexplained bleeding, bruising, skin rashes, fever, and/or sore throat signs of kidney problems such as change in the colour/amount of produced urine produced suddenly developed abdominal cramps/pain, fever, severe headache, and/or rash
Warnings & Precautions
& PRECAUTIONSPREGNANCYMESACOL ENEMA should be used with caution during pregnancy and in women planning for pregnancy only if it is clearly necessary. Consult your doctor before using MESACOL ENEMA. BREASTFEEDINGMESACOL ENEMA should be used with caution in breastfeeding women only if it is necessary, since newborn may develop allergic reactions after breastfeeding. Consult your doctor before using the medicine. DRIVING AND USING MACHINESMESACOL ENEMA is unlikely to affect your ability to drive and/or operate machines. Consult your doctor before using MESACOL ENEMA. KIDNEYMESACOL ENEMA is not recommended for use in patients with severe kidney problems. It should be used with caution in patients who have/had mild to moderate kidney disease. Consult your doctor before using MESACOL ENEMA. LIVERMESACOL ENEMA is not recommended for use in patients with severe liver problems. It should be used with caution in patients who have/had mild to moderate liver disease. Consult your doctor before using MESACOL ENEMA. ALLERGYDo not take MESACOL ENEMA if you are allergic to Mesalamine, salicylates, sulfasalazine, and/or any other ingredients of this medicine. LUNGSMESACOL ENEMA should be used with caution in patients with lung problems such as bronchial asthma. Consult your doctor before using MESACOL ENEMA. OTHERSBefore taking MESACOL ENEMA inform your doctor if you have: a medical condition that makes you prone to bleeding Use in Paediatrics: MESACOL ENEMA is not recommended for use in children and adolescents (aged below 18 years). Consult your doctor before using the medicine. Use in Geriatrics: MESACOL ENEMA should be used with caution in elderly patients (aged above 65 years). Consult your doctor before using MESACOL ENEMA.
Drug Interactions
SA. Drug-Drug interactions: Before using MESACOL ENEMA, inform your doctor if you are taking any of the following medicine: azathioprine (used after transplantations or to manage autoimmune diseases) mercaptopurine, thioguanine (medicines used to manage leukaemia) medicines used to manage blood clotting (Ex. warfarin) non- steroidal anti-inflammatory drugs (medicines used to reduce fever and provide relief from pain) Ex. ibuprofen, diclofenac, ketorolac Overdosage: If you or anyone else accidentally administers too much of MESACOL ENEMA, consult your doctor immediately or visit the nearby hospital to manage overdose symptoms. SYNOPSIS Drug : Mesalamine Pharmacological Category : Salicylates Therapeutic Indication : Ulcerative colitis Dosage Forms : Tablet, Suppositories, Sachet, Granules, Powder, Pellet, Enema MORE INFORMATION Keep MESACOL ENEMA out of reach of children Store MESACOL ENEMA at room temperature
Article Information
Written By
ity (HPRA). [Revised in August 2021] [Accessed on 15th October 2022] https://www.hpra.ie/img/uploaded/swedocuments/b393d55b-59b2-46c3-9719-6db6a00dc541.pdf 5. Ferring Leciva A/S. Electronic Medicines Compendium (EMC). [Revised in November 2021] [Accessed on 15th October 2022] https://www.medicines.org.uk/emc/files/pil.5452.pdf USEFUL DIAGNOSTIC TESTS Colonoscopy Sigmoidoscopy AUTHOR DETAILS Written By Dr. K .AZEEM HUSSAIN
Medical Content Writer
Reviewed By
Dr. Sankara Babu Gorle
Medical Expert
Last Updated
18 Nov 2022