MESACOL CR Granules 1gm
Key Information
Generic Name
Generic Name Mesalazine 1000 mg Also Known As: Mesalamine, 5-Aminosalicylic Acid
Manufacturer
Sun Pharmaceutical Industries Ltd
Country of Origin
India
Detailed Information
Introduction
INTRODUCTION ABOUT MESACOL CR GRANULESMESACOL CR GRANULES contains Mesalamine which belongs to the group of medicines called Salicylates. MESACOL CR GRANULES is used to manage mild to moderate attacks of ulcerative colitis, which is a chronic inflammatory bowel disease that affects last part of colon and rectum (back passage) in affected individuals. MESACOL CR GRANULES is not recommended for use in patients allergic to Mesalamine, salicylates (such as acetylsalisylic acid) and/or sulphasalazine. It is also not recommended for use in patients with bleeding disorders and/or serious kidney/liver disease. Before taking MESACOL CR GRANULES, inform your doctor if you suffer from an active peptic ulcer (stomach/duodenal ulcer) and/or have lung problems (such as asthma), mild to moderate kidney/liver problems. MESACOL CR GRANULES should be used with caution in pregnant and breastfeeding women only if it is clearly necessary. It is advised to be used with caution in children and adolescents (aged 6-18 years) and in elderly patients (aged above 65 years) after consulting the doctor. The most common
Uses
OF MESACOL CR GRANULES Manage mild to moderate attacks of ulcerative colitis in affected individuals
How It Works
MESACOL CR GRANULES works by suppressing the production of prostaglandins (chemical messengers responsible for inflammation in the intestines) which results in reduced inflammation and ulceration thus providing relief from ulcerative colitis (and its associated symptoms) in affected individuals.
Directions for Use
Take MESACOL CR GRANULES as advised by your physician. Empty the contents of the sachet onto the tongue and wash the granules down immediately with some water/orange juice or mix the entire content of the sachet with yogurt and immediately intake it without chewing the medicine. Your doctor will decide the exact dose and duration of management for you depending upon your age, body weight and disease condition.
Side Effects
these symptoms worsens. USES OF MESACOL CR GRANULES Manage mild to moderate attacks of ulcerative colitis in affected individuals HOW MESACOL CR GRANULES WORKSMESACOL CR GRANULES works by suppressing the production of prostaglandins (chemical messengers responsible for inflammation in the intestines) which results in reduced inflammation and ulceration thus providing relief from ulcerative colitis (and its associated symptoms) in affected individuals. DIRECTIONS FOR USETake MESACOL CR GRANULES as advised by your physician. Empty the contents of the sachet onto the tongue and wash the granules down immediately with some water/orange juice or mix the entire content of the sachet with yogurt and immediately intake it without chewing the medicine. Your doctor will decide the exact dose and duration of management for you depending upon your age, body weight and disease condition. SIDE EFFECTS OF MESACOL CR GRANULESCOMMON abdominal pain, nausea, vomiting, diarrhoea, flatulence headache rash RARE signs of inflammation of heart (myocarditis/pericarditis) such as shortness of breath, chest pain, rapid/irregular heart beats signs of inflammation of the pancreas such as back/stomach pain dizziness photosensitivity (increased sensitivity of your skin to sun and ultraviolet light) Stop taking MESACOL CR GRANULES and consult your doctor immediately in case you experience: serious skin reactions such as Stevens-Johnson syndrome, toxic epidermal necrolysis associated with symptoms such as reddish non-elevated, target-like/circular patches on the trunk associated with central blisters, skin peeling, ulcers of eyes, nose, mouth, throat and/or genitals signs of severe allergic reaction such as severe skin rashes, difficulty in breathing/swallowing, swelling of the face/neck suddenly developed abdominal cramps/pain, fever, severe headache and/or rash
Warnings & Precautions
& PRECAUTIONSPREGNANCYMESACOL CR GRANULES should be used with caution during pregnancy and in women planning for pregnancy only if it is clearly necessary. Consult your doctor before taking MESACOL CR GRANULES. BREASTFEEDINGMESACOL CR GRANULES should be used with caution in breastfeeding women only if it is clearly necessary since the medicine may cause allergic reactions in new-borns (after breastfeeding). The medicine is advised to be discontinued from use if new-borns develop diarrhoea. Consult your doctor before taking the medicine. DRIVING AND USING MACHINESMESACOL CR GRANULES is unlikely to affect your ability to drive and/or operate machines. Consult your doctor before taking MESACOL CR GRANULES. ALCOHOLConsult and inform your doctor if you are planning to consume alcohol while taking MESACOL CR GRANULES. KIDNEYMESACOL CR GRANULES is not recommended for use in patients with severe kidney problems. It should be used with caution in patients who have/had mild to moderate kidney disease. Consult your doctor before taking MESACOL CR GRANULES. LIVERMESACOL CR GRANULES is not recommended for use in patients with severe liver problems. It should be used with caution in patients who have/had mild to moderate liver disease. Consult your doctor before taking MESACOL CR GRANULES. ALLERGYDo not take MESACOL CR GRANULES if you are allergic to Mesalamine, salicylates, sulfasalazine and/or any other ingredients of this medicine. LUNGSMESACOL CR GRANULES should be used with caution in patients with lung problems such as bronchial asthma. Consult your doctor before taking MESACOL CR GRANULES. OTHERSMESACOL CR GRANULES is not recommended for use if you: suffer from bleeding disorders Before taking MESACOL CR GRANULES inform your doctor if you: have an active peptic ulcer (stomach/duodenal ulcer) Use in Paediatrics: MESACOL CR GRANULES is advised to be used with caution in children and adolescents (aged 6-18 years). Consult your doctor before administering the medicine to the child. Use in Geriatrics: MESACOL CR GRANULES should be used with caution in elderly patients (aged above 65 years). Consult your doctor before taking MESACOL CR GRANULES.
Drug Interactions
SA. Drug-Drug interactions: Before taking MESACOL CR GRANULES, inform your doctor if you are taking any of the following medicine: antacids (medicines used to relieve indigestion and heartburn) Ex. aluminum hydroxide, magnesium carbonate azathioprine (used after transplantations or to manage autoimmune diseases) mercaptopurine, thioguanine (medicines used to manage leukaemia) medicines used to manage blood clotting (Ex. warfarin) non- steroidal anti-inflammatory drugs (medicines used to reduce fever and provide relief from pain) Ex. ibuprofen, diclofenac, ketorolac Overdosage: If you or anyone else accidentally takes too much of MESACOL CR GRANULES, consult your doctor immediately or visit the nearby hospital to manage the overdose symptoms. SYNOPSIS Drug : Mesalamine Pharmacological Category : Salicylates Therapeutic Indication : Ulcerative colitis Dosage Forms : Tablets, Suppositories, Sachet, Granules, Powder, Pellet, Enema MORE INFORMATION Keep MESACOL CR GRANULES out of reach of children Store MESACOL CR GRANULES at room temperature
Article Information
Written By
ity (HPRA). [Revised in February 2022] [Accessed on 18th October 2022] https://www.hpra.ie/img/uploaded/swedocuments/9945a6a2-aeec-49e9-80b5-90d028e5154b.pdf 5. Taj Pharma India. Meslataj 0.5gm/1gm/2gm. [Accessed on 18th October 2022] https://tajpharma.in/portfolio-item/mesalazine-sachet-1gm-prolonged-release-granules-meslataj-taj-pharma/ USEFUL DIAGNOSTIC TESTS Colonoscopy Sigmoidoscopy AUTHOR DETAILS Written By Dr. K .AZEEM HUSSAIN
Medical Content Writer
Reviewed By
Dr. Sankara Babu Gorle
Medical Expert
Last Updated
18 Nov 2022