Maxgalin M ER 75mg Tablet 10'S

Neuropathic Pain (649)Rx required

Key Information

Generic Name

Generic Name MECOBALAMIN(METHYLCOBALAMIN) 1.5 mg+PREGABALIN 75 mg

Manufacturer

Sun Pharmaceutical Industries Ltd

Variant

10 Tablet(s) in a Strip

Country of Origin

India

Detailed Information

Introduction

MAXGALIN M ER 75MG TABLET is a combination of Pregabalin and Methylcobalamin which belongs to the group of medicines called Anticonvulsants and Vitamin-B complex respectively. MAXGALIN M ER 75MG TABLET is indicated for the management of neuropathic pain in adults. Neuropathic pain is a chronic painful condition caused by damage or disease affecting the somatosensory (sense of touch) nervous system (such as lesion or disease of spinal cord and/or brain). It can also be caused by prolonged diabetes mellitus, infectious diseases (such as HIV infection or leprosy), chemotherapy, auto-immune disease (Ex. Guillain-Barre syndrome) or by other metabolic dysfunctions. Symptoms include shooting, burning, or stabbing pain, tingling and numbness, spontaneous pain (pain without stimulus) or pain caused by normal daily activities that are typically not painful (such as brushing your hair, being in cold temperatures or rubbing against something). Do not stop taking MAXGALIN M ER 75MG TABLET without consulting your doctor as it could precipitate withdrawal symptoms such as headache, insomnia (lack of sleep), nausea, pain, diarrhea, flu syndrome, anxiety, nervousness, depression, convulsion, excessive sweating, dizziness and physical dependence. MAXGALIN M ER 75MG TABLET has high potential to cause addiction and therefore caution should be exercised among patients who already has a history of substance abuse. MAXGALIN M ER 75MG TABLET can cause suicidal ideation in some individuals and therefore appropriate management should be con

Uses

OF MAXGALIN M ER 75MG TABLET Manage neuropathic pain in adults

How It Works

MAXGALIN M ER 75MG TABLET effectively alleviates the symptoms of various types of neuropathic pain, where methylcobalamin acts by rejuvenating the damaged neurons by improving the production of myelin (a substance that covers and protects the nerve fibers from damage) and pregabalin acts by interfering with various pain signals travelling through the damaged nerves and the brain, thus leading to a significant pain relief in various neuropathic pain states.

Directions for Use

Take MAXGALIN M ER 75MG TABLET as advised by your physician. Swallow MAXGALIN M ER 75MG TABLET with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration of MAXGALIN M ER 75MG TABLET for you depending upon your age, body weight and disease condition.

Side Effects

taking MAXGALIN M ER 75MG TABLET are dizziness, sleepiness, headache, dry mouth, mood changes, fluid retention and weight gain. Consult your doctor if any of the side effects worsen. USES OF MAXGALIN M ER 75MG TABLET Manage neuropathic pain in adults HOW MAXGALIN M ER 75MG TABLET WORKSMAXGALIN M ER 75MG TABLET effectively alleviates the symptoms of various types of neuropathic pain, where methylcobalamin acts by rejuvenating the damaged neurons by improving the production of myelin (a substance that covers and protects the nerve fibers from damage) and pregabalin acts by interfering with various pain signals travelling through the damaged nerves and the brain, thus leading to a significant pain relief in various neuropathic pain states. DIRECTIONS FOR USETake MAXGALIN M ER 75MG TABLET as advised by your physician. Swallow MAXGALIN M ER 75MG TABLET with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration of MAXGALIN M ER 75MG TABLET for you depending upon your age, body weight and disease condition. SIDE EFFECTS OF MAXGALIN M ER 75MG TABLETCOMMON dizziness, sleepiness, headache nasopharyngitis (common cold) nausea, vomiting, increased appetite, constipation, diarrhea, flatulence, abdominal distension, dry mouth euphoric mood (feeling excited or pleasurable) confusion, irritability, disorientation insomnia (lack of sleep) decrease in sex drive, erectile dysfunction ataxia (impaired balance or coordination), tremor (shaking) dysarthria (disorder of speech) memory impairment, attention disturbance paresthesia (tingling and numbness in extremities) hypoaesthesia (decreased sense of touch) tiredness blurred vision vertigo (spinning sensation) muscle cramps pain in limbs, joints or back cervical spasm (a sudden, involuntary contraction of a muscle in the neck) peripheral edema fall (accidental injury) weight gain UNCOMMON abnormally low count of a type of white blood cell (neutrophils) loss of appetite low blood sugar levels hallucination, panic attack, restlessness, agitation, depression elevated mood, aggression, mood swings, depersonalisation, word finding difficulty abnormal dreams, libido increased, anorgasmia, apathy fainting, unresponsiveness (stupor) myoclonus (muscle jerks) loss of consciousness, psychomotor hyperactivity dizziness postural involuntary eye movement cognitive disorder mental impairment hyporeflexia (reduction or absence of normal bodily reflexes) hyperaesthesia (excessive physical sensitivity) burning sensation loss of sensation of taste general discomfort visual disturbance, eye swelling eye pain or strain photopsia (presence of flashes of light or floaters in the vision) dry eye lacrimation increased, eye irritation disorder in loudness perception fast or slow heart rate, congestive heart failure increased or decreased blood pressure hot flushes, flushing, peripheral coldness shortness of breath, bleeding from nose cough, nasal congestion stuffy nose, snoring, nasal dryness gastrooesophageal reflux disease, salivary hypersecretion oral numbness rash popular, urticaria, itching excess sweating joint swelling, muscle or neck pain muscle twitching or stiffness urinary incontinence, painful urination sexual dysfunction, ejaculation delayed pain menstruation or breast pain generalised oedema, face oedema, chest tightness, pain fever, thirst, chills, lack of energy decreased weight RARE disinhibition (a pattern of antisocial, impulsive, norm-violating tendency) convulsions parosmia (a smell disorder) dysgraphia (trouble in writing) heart problems (such as prolonged QT interval, sinus tachycardia or sinus arrhythmia) pulmonary edema (fluid retention in the lungs) and throat tightness GI tract problems (such as fluid buildup in stomach, pancreatitis, swollen tongue, or dysphagia) cold sweats kidney problems (such as renal failure, oliguria, and urinary retention) amenorrhea (lack of menstrual periods) breast discharge or enlargement gynecomastia (breast enlargement in males) Stop taking MAXGALIN M ER 75MG TABLET and contact your doctor immediately if you experience any of the following side effects: severe allergic reactions (such as skin rash, itching, swelling of the face, lips, throat, neck, and difficulty in breathing) symptoms of elevated creatine kinase (such as unexplained muscle pain, tenderness, or weakness, accompanied by malaise or fever) rhabdomyolysis (severe muscle injury) suicidal ideation or behavior

Warnings & Precautions

& PRECAUTIONSPREGNANCYThere is no proper information on the use of MAXGALIN M ER 75MG TABLET during pregnancy and therefore should be used only if the benefit to the mother clearly outweighs the potential risk to the fetus. Consult your doctor before taking MAXGALIN M ER 75MG TABLET. Women of childbearing potential should use a suitable contraceptive method to avoid pregnancy while taking MAXGALIN M ER 75MG TABLET. BREASTFEEDINGMAXGALIN M ER 75MG TABLET is not recommended for use in breastfeeding women unless it is considered clearly necessary. Consult your doctor whether to discontinue breast-feeding or to discontinue therapy with MAXGALIN M ER 75MG TABLET. DRIVING AND USING MACHINESDo not drive or operate any heavy tools or machines if you experience dizziness or sleepiness after taking this medicine. Consult your doctor before taking MAXGALIN M ER 75MG TABLET. ALCOHOLAvoid consumption of alcohol while taking MAXGALIN M ER 75MG TABLET, as it may cause impairment of motor skills and sedating effects of alcohol. Consult your doctor before taking MAXGALIN M ER 75MG TABLET. KIDNEYMAXGALIN M ER 75MG TABLET should be taken with caution in patients with impaired kidney function. Consult your doctor before taking MAXGALIN M ER 75MG TABLET. LIVERMAXGALIN M ER 75MG TABLET should be taken with caution in patients with liver disease. Consult your doctor before taking MAXGALIN M ER 75MG TABLET. ALLERGYDo not take MAXGALIN M ER 75MG TABLET if you are allergic to Pregabalin, Methylcobalamin or any other ingredients of MAXGALIN M ER 75MG TABLET. HEART DISEASEMAXGALIN M ER 75MG TABLET should be taken with caution in patients with heart disease (such as congestive heart failure). Consult your doctor before taking MAXGALIN M ER 75MG TABLET. OTHERSMAXGALIN M ER 75MG TABLET is not recommended for use if you: have Leber’s disease (a hereditary eye disease) have problems in glucose metabolism (Ex. galactose intolerance, Lapp lactase deficiency or glucose-galactose malabsorption) Before taking this medicine, inform your physician if you: have history of misuse or substance abuse have folate deficiency have diabetes have epilepsy have or at risk of encephalopathy (a brain disease) Use in pediatrics: MAXGALIN M ER 75MG TABLET is not recommended for use in children and adolescents (aged below 18 years) due to lack of safety data. Consult your child’s doctor for advice. Use in geriatrics: MAXGALIN M ER 75MG TABLET should be used with caution in elderly patients (aged 65 years and above), especially in patients with decreased renal function. Proper dose adjustments and careful monitoring of kidney function are required in such patients. Consult your doctor before taking MAXGALIN M ER 75MG TABLET.

Drug Interactions

SA. Drug-Drug interactions: Before taking MAXGALIN M ER 75MG TABLET, inform your doctor, if you are taking any of the following medicines: medicines used to reduce blood glucose level (Ex. metformin, pioglitazone, rosiglitazone) anti-spasticity agents (used to reduce muscle stiffness) Ex. dantrolene, baclofen opioid analgesics (Ex. morphine, pethidine) (used to manage severe pain) CNS depressants (Ex. lorazepam) (used to manage anxiety) oral contraceptives (birth control pills) Ex. norethisterone and/or ethinyl estradiol chloramphenicol (an antibiotic used to manage bacterial infections) large doses of folic acid (a vitamin supplement) vitamin C supplements medicines used to control blood cholesterol levels (Ex. cholestyramine or colestipol) colchicine (used to manage gout) para-amino salicylic acid (used to manage tuberculosis) potassium chloride (used to manage low potassium levels) nitrous oxide (an anesthetic) Overdosage: If you or anyone else accidentally take too much of MAXGALIN M ER 75MG TABLET, contact your doctor immediately or go to a hospital straight away. Overdosage symptoms of MAXGALIN M ER 75MG TABLET might include sleepiness, confusion, agitation, restlessness, seizures and coma. SYNOPSIS Drug : Pregabalin, Methylcobalamin Pharmacological Category : Anticonvulsants, Vitamin B complex Therapeutic Indication : Neuropathic pain Dosage Forms : Tablet, Capsule, Soft gels MORE INFORMATION Keep MAXGALIN M ER 75MG TABLET out of reach of children Store MAXGALIN M ER 75MG TABLET at room temperature

Article Information

DW

Written By

DETAILS Written By Dr. R. Dinesh John Rajkumar

Medical Content Writer

DS

Reviewed By

Dr. Sankara Babu Gorle

Medical Expert

Last Updated

03 Dec 2022

Tags

#neuropathic pain (649)#generic name mecobalamin(methylcobalamin) 1.5 mg+pregabalin 75 mg