Malirid Tablet 7'S
Key Information
Generic Name
Generic Name Primaquine 7.5 mg
Manufacturer
Ipca Laboratories Ltd
Variant
7 Tablet(s) in a Strip
Country of Origin
India
Detailed Information
Introduction
INTRODUCTIONMALIRID contains Primaquine which belongs to the group of medicines called Antimalarial drugs. It is used to manage malarial infections and to prevent its relapse. Malaria is a parasitic infection caused due to different spices of a malarial parasites (such as plasmodium vivax and Plasmodium ovale). It occurs due to bites of mosquitoes infected with the malarial parasites. Symptoms of malarial infection may include fever, chills, sweating, headache, nausea, vomiting, body pain, general discomfort etc. Before taking MALIRID inform your doctor if you have any liver, kidney, or heart disease. You must also inform your doctor if you have anemia, any infections or low WBC counts due to underlying autoimmune diseases (such as rheumatoid arthritis or lupus erythematosus) before taking MALIRID. MALIRID should not be used in pregnant or breastfeeding women as it may cause serious harm to the growing fetus or the nursing infant. Both men and women receiving MALIRID must use a suitable contraceptive method to avoid pregnancy while undergoing therapy with MALIRID and for 2-3 months after discontinuation of therapy. MALIRID may cause low red blood cell count and white blood cell count in your blood. To manage this, your doctor will periodically monitor your blood cell count and adjust the dose accordingly. Other common
Uses
OF MALIRID Manages and prevents malarial infection
How It Works
MALIRID is an antiparasitic medicine. It controls the growth and multiplication of malarial parasites within the body. It interacts with the parasites and disrupts their energy sources (mitochondria), which leads to the death of the parasite. It also prevents the relapses of infection by killing the malarial parasites during their early stages within the liver before they get released into the blood stream.
Directions for Use
Take MALIRID preferably after meals or as directed by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose, duration and frequency of administration depending upon your age, body weight and severity of infection. Do not stop taking MALIRID without consulting your doctor even if you feel better. Continue to take MALIRID for the stipulated duration mentioned by your doctor to achieve maximum benefits.
Side Effects
taking MALIRID are nausea, vomiting, stomach pain or heartburn. Consult your doctor if any of these side effects trouble you. USES OF MALIRID Manages and prevents malarial infection HOW MALIRID WORKSMALIRID is an antiparasitic medicine. It controls the growth and multiplication of malarial parasites within the body. It interacts with the parasites and disrupts their energy sources (mitochondria), which leads to the death of the parasite. It also prevents the relapses of infection by killing the malarial parasites during their early stages within the liver before they get released into the blood stream. DIRECTIONS FOR USETake MALIRID preferably after meals or as directed by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose, duration and frequency of administration depending upon your age, body weight and severity of infection. Do not stop taking MALIRID without consulting your doctor even if you feel better. Continue to take MALIRID for the stipulated duration mentioned by your doctor to achieve maximum benefits. SIDE EFFECTS OF MALIRIDCOMMON nausea, vomiting stomach pain or discomfort dizziness anemia (low RBC count) heart burn skin rash low WBC count RAREStop taking MALIRID and contact your doctor immediately if you experience any of the following side effects: severe allergic reactions (such as skin rash, severe itching of the skin with raised lumps, blisters in the skin, swelling of the face, lips, tongue and/or throat with difficulty in breathing or swallowing) signs of hemolytic anemia (such as darkening of the urine, pale skin, dizziness, confusion, fatigue, light-headedness, shortness of breath) bluish lips or nails
Warnings & Precautions
& PRECAUTIONSPREGNANCY[GBNKEYWORD is not recommended for use if you are pregnant women. Therefore, inform your doctor if you are pregnant or planning to become pregnant before taking MALIRID. Women of childbearing potential must use a suitable contraceptive method to prevent pregnant while undergoing therapy with MALIRID and 2 months after discontinuation of the therapy. BREASTFEEDING[GBNKEYWORD is not recommended for use if you are breastfeeding women. Therefore, consult your doctor before taking it. DRIVING AND USING MACHINESDo not drive or operate any heavy tools or machines if you feel dizzy after taking MALIRID. ALCOHOLAvoid consumption of alcohol while undergoing therapy with MALIRID. KIDNEYMALIRID should be used with caution in patients with kidney disease. Therefore, consult your doctor for advice before taking it. LIVERMALIRID should be used with caution in patients with liver disease. Therefore, consult your doctor for advice before taking it. ALLERGYDo not take MALIRID if you are allergic to Primaquine. HEART DISEASEMALIRID should be used with caution in patients who have or previously had any heart disease (such as irregular heart rate). Therefore, consult your doctor for advice before taking it. OTHERSMALIRID is not recommended for use if you: have severe glucose-6-phosphate dehydrogenase (G6PD) deficiency are severely ill or have granulocytopenia (low WBC count) due to rheumatoid arthritis or lupus erythematosus received another antimalarial drug called quinacrine recently have bone marrow disorder Before taking MALIRID inform your physician if you: have a family history of G6PD deficiency have a rare blood disorder called NADH methemoglobin reductase deficiency have anemia (low RBC in blood) have hemolytic anemia (destruction of RBC in blood) have low potassium or magnesium levels in the blood Use in pediatrics: MALIRID should be used in children and adolescents (aged below 18 years) only if prescribed by the physician. It should not be used in young children weighing less than 20 kg. Therefore, consult your doctor before administration. Use in geriatrics: The safety and effectiveness of MALIRID have not been established in the elderly patients (aged 65 years or above). Therefore, MALIRID should be used in elderly patients only if considered necessary by the physician. Your doctor will prescribe you a suitable dose after analyzing your heart, kidney, and liver functions.
Drug Interactions
SA. Drug-Drug interactions: Before taking MALIRID inform your doctor if you are taking any of the following medicines: other medicines used to manage malaria (such as mepacrine, quinacrine, halofantrine, chloroquine or pyronaridine artesunate, dihydroartemisinin-piperaquine) pentamidine- used to manage fungal infection medicines used to manage arrythmia (such as quinidine, amiodarone, procainamide, disopyramide) medicines used to manage depression (such as fluoxetine, paroxetine amitriptyline or imipramine) medicines used to manage psychiatric disorders (such as chlorpromazine, trihexyphenidyl) medicines used to manage bacterial infections (such as erythromycin, moxifloxacin) medicines that can depress the functions of bone marrow or damage the RBC or WBC in blood such as anticancer agents (Ex. carboplatin, busulfan, bendamustine), anti-infectives (sulfonamides, dapsone, cotrimoxazole, quinolones), colchicine, methylene blue, penicillamine, gold salts digoxin (a medicine used to manage abnormal heart rate) dabigatran (a medicine used to prevent blood clots) theophylline (a medicine used to manage breathing problems) alosetron (a medicine used to manage vomiting) tizanidine (a medicines used to manage muscle spasm) B. Drug - Food interaction: Avoid drinking grapefruit juice while taking this medicine as it may increase the risk of side effects. Overdosage: If you or anyone else accidentally took more MALIRID, contact your doctor immediately or visit a nearby hospital. Symptoms of overdosage might include vomiting, stomach pain or cramps, heart burn, heart rhythm problems tiredness, yellowing of the skin and the whites of the eyes, dizziness, confusion, difficulty in breathing, trouble in sleeping, bluish discoloration of the skin or pale skin. SYNOPSIS Drug : Primaquine Pharmacological Category : 8-Aminoquinoline antiprotozoal agents Therapeutic Indication : Malaria Dosage Forms : Tablet MORE INFORMATION Keep out of reach of children Store between 15-30°C