Lupisoz D Capsule 10'S

Ulcer/Reflux/Flatulence (1085)Rx required

Key Information

Generic Name

Generic Name Domperidone 30 mg+Esomeprazole 40 mg

Manufacturer

Lupin Ltd

Variant

10 Capsule(s) in a Strip

Country of Origin

India

Detailed Information

Introduction

INTRODUCTION ABOUT LUPISOZ D CAPSULELUPISOZ D CAPSULE is a combination of Domperidone and Esomeprazole which belongs to the group of medicines called Prokinetic Drugs and Proton pump inhibitors respectively. It is used in adults to manage peptic ulcers, gastroesophageal reflux disease (GERD) and Zollinger-Ellison syndrome (tumors in pancreas causing the stomach to secrete more acid). LUPISOZ D CAPSULE acts by reducing the production of gastric acid. It also speeds up the movement of food from the stomach to the intestines, thereby reducing the signs of nausea, vomiting and acid reflux. Due to these actions, it can also reduce the unpleasant signs of GI tract such as nausea, vomiting, indigestion, burping, bloating, acidity or heartburn. LUPISOZ D CAPSULE is effective in managing peptic ulcer caused either due to stomach infection (H. pylori infection) or due to prolong use of non-steroidal anti-inflammatory drugs (such as ibuprofen, Aceclofenac etc). It can also be used to manage re-bleeding from the ulcers. GERD is a chronic digestive disease in which the acid from the stomach frequently flows into the esophagus leading to irritation of lining of food pipe. Symptoms include heartburn, chest pain, nausea, sensation of lump in throat and stomach discomfort. LUPISOZ D CAPSULE should be taken at least 30 minutes before meals. During management with LUPISOZ D CAPSULE your doctor will closely monitor your kidney functions, liver functions and blood magnesium levels to avoid the risk of unwanted

Uses

OF LUPISOZ D CAPSULEIt is used in adults to manage: Peptic ulcers Gastrointestinal Reflux disease (GERD) Zollinger-Ellison syndrome (tumors in pancreas causing the stomach to secrete more acid) Nausea and Vomiting Acidity, Heartburn, Indigestion, Burping, Bloating

How It Works

LUPISOZ D CAPSULE contains two medicines namely Domperidone and Esomeprazole. Domperidone works by blocking the actions of a chemical messenger called dopamine in the gut and across the brain and spinal cord. This action stimulates the gut, reduces acid reflux and speeds up the movements of food from the stomach into the intestines. It also blocks the transmission of nerve signals between the vomiting centers and the brain which reduces the onset of nausea and vomiting. Esomeprazole reduces gastric acid secretion by the blocking the actions of a protein membrane called H+K+Atpase (proton pump) present in the lining of the stomach. By reducing stomach acid production, LUPISOZ D CAPSULE manages the worsening of ulcers, heals the existing ulcers and esophageal lesions and provides relief from the unpleasant symptoms of GI tract (such as acidity, bloating, burping and indigestion).

Directions for Use

Take LUPISOZ D CAPSULE 30 minutes to 1 hour before meals or as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition. Do not stop taking LUPISOZ D CAPSULE unless your doctor advice you to stop.

Side Effects

taking LUPISOZ D CAPSULE are dryness of mouth, constipation and flatulence. Consult your doctor if any of these side effect bothers you. USES OF LUPISOZ D CAPSULEIt is used in adults to manage: Peptic ulcers Gastrointestinal Reflux disease (GERD) Zollinger-Ellison syndrome (tumors in pancreas causing the stomach to secrete more acid) Nausea and Vomiting Acidity, Heartburn, Indigestion, Burping, Bloating HOW LUPISOZ D CAPSULE WORKSLUPISOZ D CAPSULE contains two medicines namely Domperidone and Esomeprazole. Domperidone works by blocking the actions of a chemical messenger called dopamine in the gut and across the brain and spinal cord. This action stimulates the gut, reduces acid reflux and speeds up the movements of food from the stomach into the intestines. It also blocks the transmission of nerve signals between the vomiting centers and the brain which reduces the onset of nausea and vomiting. Esomeprazole reduces gastric acid secretion by the blocking the actions of a protein membrane called H+K+Atpase (proton pump) present in the lining of the stomach. By reducing stomach acid production, LUPISOZ D CAPSULE manages the worsening of ulcers, heals the existing ulcers and esophageal lesions and provides relief from the unpleasant symptoms of GI tract (such as acidity, bloating, burping and indigestion). DIRECTIONS FOR USETake LUPISOZ D CAPSULE 30 minutes to 1 hour before meals or as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition. Do not stop taking LUPISOZ D CAPSULE unless your doctor advice you to stop. SIDE EFFECTS OF LUPISOZ D CAPSULECOMMON headache diarrhea stomach pain constipation flatulence nausea vomiting benign polyps in the stomach UNCOMMON dry mouth low sex drive dizziness drowsiness anxiety sleeplessness skin rash or itchiness breast enlargement in both men and in women feeling weak swelling of body parts (oedema) fragile bones (risk of bone fracture) abnormal liver function tests RARE low WBC or platelet counts in blood signs of low sodium levels in blood (weakness, being sick and cramps) mouth ulcers hair loss fungal infection of the gut (thrush) Stop taking LUPISOZ D CAPSULE and inform your doctor immediately if you experience any of the following side effects such as: severe allergic reactions (such as skin rash, itching, swelling of the lips, face or body and difficulty in breathing or swallowing) signs of liver problems (yellowing of the skin and eyes, dark urine and tiredness) severe skin reactions (such as redness, blistering, peeling of skin and bleeding in the lips, eyes, mouth, nose and genitals with fever) chest pain, fast or irregular heartbeat, difficulty in breathing, feeling faint fits uncontrollable body movements (including eye and tongue), twisted neck and abnormal body posture signs of low magnesium levels in blood (such as tiredness, abnormal muscle movements, dizziness, confusion, disorientation, irregular heartbeat) skin rashes on sun exposed areas with or without joint pain sudden weight loss, looking pale and weak (anemia) signs of bleeding in the gut (such as bloody vomits/stools)

Warnings & Precautions

& PRECAUTIONSPREGNANCYMonitoring requiredLUPISOZ D CAPSULE should be used in pregnant women only if it is considered necessary by the physician. Therefore, consult your doctor before taking it. BREASTFEEDINGMonitoring requiredLUPISOZ D CAPSULE may pass through breast milk. Therefore, it is not recommended for use in breastfeeding women unless considered necessary by the physician. DRIVING AND USING MACHINESUse with CautionLUPISOZ D CAPSULE does not affect your ability in driving or handling heavy tools or machines. However, do not drive or handle heavy tools or machines if your ability is affected by LUPISOZ D CAPSULE. ALCOHOLConsult your doctorAvoid consumption of alcohol while taking LUPISOZ D CAPSULE, as it could aggravate your existing condition. KIDNEYUse with CautionLUPISOZ D CAPSULE should be used with caution in patients with kidney problems. Therefore, consult your doctor before taking it. LIVERConsult your doctorLUPISOZ D CAPSULE is not recommended for use in patients with moderate or severe liver impairment. It should be used with caution in patients with other mild liver problems. Therefore, consult your doctor before taking it. ALLERGYContraindicatedDo not take LUPISOZ D CAPSULE if you are allergic to Domperidone, Esomeprazole or to any other proton pump inhibitors (such as rabeprazole, pantoprazole). HEART DISEASEContraindicatedLUPISOZ D CAPSULE is not recommended for use in patients having heart problems (such as prolongation of QT wave, congestive heart failure or arrhythmia). Therefore, consult your doctor before taking it. USE IN PEDIATRICSContraindicatedLUPISOZ D CAPSULE is not recommended for use in children and adolescents (aged below 18 years) due to lack of safety data. However, consult your doctor before taking it. USE IN GERIATRICSUse with CautionLUPISOZ D CAPSULE should be used with caution in elderly patients (aged 65 years and above). Therefore, consult your doctor before taking it. OTHERSLUPISOZ D CAPSULE is not recommended for use if you: have bloody stools or bleeding in the gut have blockage or tear in the intestines have severe fluid or electrolyte disturbances have prolactinoma (a non-cancerous tumor of pituitary gland) have low blood potassium or magnesium levels have hyperkalemia (high blood potassium levels) Before taking LUPISOZ D CAPSULE inform your doctor if you: have osteoporosis have vitamin B12 deficiency (sore tongue, mouth ulcers, pale skin, depression) are going to test Chromogranin A level

Drug Interactions

SA. Drug-Drug interactions: Before taking LUPISOZ D CAPSULE inform your doctor if you are taking any of the following medicines such as: other medicines used to manage gastrointestinal problems (Ex. cisapride, dolasetron, prucalopride, diphemanil, bepridil, methadone, omeprazole, lansoprazole, rabeprazole, ranitidine, famotidine) medicines used to manage arrhythmia or other heart problems (Ex. digoxin, apomorphine, disopyramide, hydroquinidine, quinidine, amiodarone, dofetilide, dronedarone, ibutilide, sotalol, diltiazem, or verapamil) medicines used to manage HIV infection (Ex. atazanavir, nelfinavir, saquinavir) antipsychotics (used to manage mental illness) Ex. haloperidol, pimozide, sertindole antidepressants (used to manage depression) Ex. escitalopram, citalopram, imipramine, St. John’s Wort antibiotics (used to manage bacterial infections) Ex. moxifloxacin, erythromycin, levofloxacin, clarithromycin, telithromycin, or amoxicillin medicines used to manage malaria (Ex. halofantrine, lumefantrine) antihistamines (used to manage allergies) Ex. mizolastine, mequitazine medicines used to manage cancer (Ex. toremifene, vandetanib, vincamine, erlotinib, dasatinib, nilotinib) methotrexate (used to manage cancer and auto-immune disease) tacrolimus (used to manage graft rejection) ketoconazole, itraconazole or voriconazole (used to manage fungal infection) rifampicin (used to manage tuberculosis) apomorphine (used to manage Parkinson’s disease) diazepam (used to manage anxiety) phenytoin (used to manage epilepsy) cilostazol (used to manage pain in legs) warfarin (used for blood thinning) clopidogrel (used to manage or manage blood clots) B. Drug-Food interaction: Try to take this medicine before meals to achieve maximum efficacy. Overdosage: If you or anyone else accidentally took more LUPISOZ D CAPSULE, contact your doctor immediately or go to a hospital straight away. Symptoms of overdosage might include sleepiness, confusion, uncontrollable body movements (including eye and tongue), twisted neck and abnormal posture. SYNOPSIS Drug : Domperidone, Esomeprazole Pharmacological Category : Dopamine antagonist, Proton-pump inhibitor Therapeutic Indication : GERD, Peptic ulcer, Zollinger-Ellison syndrome Acidity, Heartburn, Indigestion Dosage Forms : Tablet, Capsule MORE INFORMATIONSTORAGE Keep LUPISOZ D CAPSULE out of the sight and reach of children Store LUPISOZ D CAPSULE at room temperature

Frequently Asked Questions

Common questions and answers about Lupisoz D Capsule 10'S.

Q

What is LUPISOZ D CAPSULE used for?

A

LUPISOZ D CAPSULE is used to manage peptic ulcers, GERD and Zollinger Ellison Syndrome. It can also be used to manage nausea, vomiting, bloating, burping, acidity and heartburn.

Q

How and when to take LUPISOZ D CAPSULE?

A

Take LUPISOZ D CAPSULE at least 30 minutes to 1 hour before meals. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition.

Q

How long should I take LUPISOZ D CAPSULE?

A

You need to take LUPISOZ D CAPSULE for the stipulated duration prescribed by your doctor. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition.

Q

What to do if I forgot to take a dose of LUPISOZ D CAPSULE?

A

If you forgot to take a dose of LUPISOZ D CAPSULE, take it as soon as you remember. However, if it is time for the next dose of LUPISOZ D CAPSULE, skip the missed dose and take the next one regularly. Do not take a double dose of LUPISOZ D CAPSULE to compensate the missed ones.

Q

What are the most common side effects of taking LUPISOZ D CAPSULE?

A

The most common side effects of taking LUPISOZ D CAPSULE are dryness of mouth, constipation and flatulence. Consult your doctor if any of these side effect bothers you.

Q

Can I stop taking LUPISOZ D CAPSULE without consulting your doctor?

A

No. You should not stop taking LUPISOZ D CAPSULE without consulting your doctor because it may lead to reversal of symptoms. If you feel better after using LUPISOZ D CAPSULE, consult your doctor for advice.

Q

Will taking a higher dose of LUPISOZ D CAPSULE be more effective?

A

No, taking a higher dose of LUPISOZ D CAPSULE will not be effective, rather it can lead to toxicity. Always take the dose prescribed by your doctor. If the prescribed dose is not effective for you, consult your doctor for advice. Your doctor might increase the dose or suggest an alternative therapy.

Q

What precautions do I need to follow while taking LUPISOZ D CAPSULE?

A

Make sure to take LUPISOZ D CAPSULE 30 minutes before meals. Before taking LUPISOZ D CAPSULE inform your doctor if you have any liver, kidney or heart problems. You must also inform your doctor if you have any blockage or tears in the gut or have weak bones. Consult your doctor before taking LUPISOZ D CAPSULE if you are pregnant or breastfeeding. Regularly visit your doctor and take all the blood tests recommended by your doctor without fail.

Q

Can I take medication for high blood pressure along with LUPISOZ D CAPSULE?

A

It is not advisable to take medicines to control blood pressure while taking LUPISOZ D CAPSULE without consulting your doctor as they have known interactions with LUPISOZ D CAPSULE.

Q

Can LUPISOZ D CAPSULE be used in pregnant women?

A

LUPISOZ D CAPSULE should be used in pregnant women only if it is considered necessary by the physician. Therefore, consult your doctor before taking it.

Q

How much LUPISOZ D CAPSULE should I take?

A

LUPISOZ D CAPSULE should be used only under medical supervision. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body condition and severity of the disease condition.

Q

Can LUPISOZ D CAPSULE cause constipation?

A

Yes. Constipation is a common side effect of using LUPISOZ D CAPSULE. Eat plenty of fiber rich foods such as fresh fruits, vegetables, cereals as well as drink plenty of water and exercise more regularly when taking this medicine. Contact your doctor if this side effect bothers you.

Q

Can LUPISOZ D CAPSULE cause dry mouth?

A

Yes. Dry mouth is an uncommon side effect of using LUPISOZ D CAPSULE. Contact your doctor if this side effect bothers you.

Article Information

DW

Written By

DETAILS Written By Dr. Janet.C

Medical Content Writer

DS

Reviewed By

Dr. Sankara Babu Gorle

Medical Expert

Last Updated

23 Sep 2024

Tags

#ulcer/reflux/flatulence (1085)#generic name domperidone 30 mg+esomeprazole 40 mg