Lugonist 3.75mg Injection 1ml
Key Information
Generic Name
Generic Name Leuprolide 3.75 mg Also Known As: Leuprorelin
Manufacturer
Zydus Healthcare Ltd
Country of Origin
India
Detailed Information
Introduction
INTRODUCTION ABOUT LUGONIST 3.75MG INJECTIONLUGONIST 3.75MG INJECTION contains Leuprolide which belongs to the group of medicines called Gonadotropin Releasing Hormone (GnRH) agonist. It is used to manage endometriosis, relieving pain and reducing endometriotic lesions. It is also used for preoperative hematologic improvement in women having fibroids (abnormal growth in uterus) induced anaemia for whom hormonal suppression is con
Uses
OF LUGONIST 3.75MG INJECTIONIt is used: to manage endometriosis, relieving pain and reducing endometriotic lesions for preoperative hematologic improvement in women having fibroids induced anaemia for whom hormonal suppression is con
How It Works
LUGONIST 3.75MG INJECTION contains Leuprolide which helps in managing endometriosis and fibroids. It works by blocking the secretion of gonadotropin releasing hormone (GnRH) following an initial stimulation, resulting in suppression of ovarian and testicular steroidogenesis (process of synthesis of steroid hormones), thereby relieving the symptoms associated with increased levels of sex hormones.
Directions for Use
LUGONIST 3.75MG INJECTION will be administered to you only by a doctor or a nurse intramuscularly (into the muscle). Your doctor will adminster the correct dose and duration for you depending upon your age, body weight and disease condition.
Side Effects
LUGONIST 3.75MG INJECTION are hot flashes/sweating, general pain, headache, gastrointestinal disorders, swelling due to water retention, nausea, vomiting, reduced libido, and dizziness. Consult your doctor if any of these side effects worsens. USES OF LUGONIST 3.75MG INJECTIONIt is used: to manage endometriosis, relieving pain and reducing endometriotic lesions for preoperative hematologic improvement in women having fibroids induced anaemia for whom hormonal suppression is considered necessary for three months HOW LUGONIST 3.75MG INJECTION WORKSLUGONIST 3.75MG INJECTION contains Leuprolide which helps in managing endometriosis and fibroids. It works by blocking the secretion of gonadotropin releasing hormone (GnRH) following an initial stimulation, resulting in suppression of ovarian and testicular steroidogenesis (process of synthesis of steroid hormones), thereby relieving the symptoms associated with increased levels of sex hormones. DIRECTIONS FOR USELUGONIST 3.75MG INJECTION will be administered to you only by a doctor or a nurse intramuscularly (into the muscle). Your doctor will adminster the correct dose and duration for you depending upon your age, body weight and disease condition. SIDE EFFECTS OF LUGONIST 3.75MG INJECTIONCOMMON hot flashes/sweating headache vaginitis (inflammation in the vagina) depression/emotional lability general pain weight gain or loss nausea vomiting reduced libido dizziness acne skin reactions joint disorder oedema (swelling due to water retention) paraesthesia (sensation of burning and pricking) gastrointestinal disturbances neuromuscular disorders breast changes or breast pain nervousness extreme weakness urinary tract infection Stop receiving LUGONIST 3.75MG INJECTION and contact your doctor if you experience any of the following side effects: signs of pituitary apoplexy such as sudden headache, visual changes, vomiting, weakened eye muscles, altered mental status, sudden loss of heart function urinary tract infection renal calculus (kidney stones) depression
Warnings & Precautions
& PRECAUTIONSPREGNANCYContraindicatedLUGONIST 3.75MG INJECTION is not recommended for use during pregnancy as it may increase the risk of pregnancy complications such as early pregnancy loss and foetal harm. Consult your doctor before receiving. BREASTFEEDINGMonitoring requiredLUGONIST 3.75MG INJECTION should be used with caution breastfeeding women only if considered necessary because it is not known whether it can pass through milk. Consult your doctor before receiving. KIDNEYUse with CautionLUGONIST 3.75MG INJECTION should be used with caution in patients with renal impairment. Consult your doctor before receiving. LIVERUse with CautionLUGONIST 3.75MG INJECTION should be used with caution in patients with hepatic impairment. Consult your doctor before receiving. ALLERGYContraindicatedDo not receive LUGONIST 3.75MG INJECTION if you are allergic to Leuprolide, GnRH, GnRH agonist analogs, or to any of the other ingredients of this medicine. USE IN PEDIATRICSContraindicatedLUGONIST 3.75MG INJECTION is not recommended for use in premenarcheal children and adolescents (below 18 years). Consult your doctor before receiving. USE IN GERIATRICSContraindicatedLUGONIST 3.75MG INJECTION is not recommended for use in postmenopausal women. Consult your doctor before receiving. OTHERSLUGONIST 3.75MG INJECTION is not recommended for use if you: have undiagnosed abnormal uterine bleeding Before receiving LUGONIST 3.75MG INJECTION, inform your doctor if you: have strong family history of osteoporosis
Drug Interactions
SA. Drug-Drug Interactions: Before receiving LUGONIST 3.75MG INJECTION, inform your doctor, if you are taking any of the following medicine: medicines used to manage convulsions (Ex. carbamazepine) corticosteroids (Ex. dexamethasone) Overdosage: LUGONIST 3.75MG INJECTION will be administered to you only by a doctor or nurse in a hospital, and so it is unlikely to receive an overdose. If you or anyone else accidentally receives too much of this medicine, consult your doctor immediately or visit the nearby hospital. SYNOPSIS Drug : Leuprolide Pharmacological Category : Gonadotropin Releasing Hormone (GnRH) agonist Therapeutic Indication : Endometriosis, Fibroids Dosage Forms : Injection, Injection depot MORE INFORMATION Keep LUGONIST 3.75MG INJECTION out of reach of children Store between 2-8°C
Frequently Asked Questions
Common questions and answers about Lugonist 3.75mg Injection 1ml.
What is LUGONIST 3.75MG INJECTION used for?
LUGONIST 3.75MG INJECTION is used to manage endometriosis, relieving pain, and reducing endometriotic lesions. It is also used for preoperative hematologic improvement in women having fibroids (abnormal growth in uterus) induced anaemia for whom hormonal suppression is considered necessary for three months. Consult your doctor before receiving.
What side effects are seen with LUGONIST 3.75MG INJECTION?
The common side effects associated with the use of LUGONIST 3.75MG INJECTION are hot flashes/sweating, general pain, headache, gastrointestinal disorders, swelling due to water retention, nausea, vomiting, reduced libido, and dizziness. Consult your doctor if any of these side effects worsens.
Who should avoid receiving LUGONIST 3.75MG INJECTION?
Do not receive LUGONIST 3.75MG INJECTION if you are allergic to Leuprolide, GnRH, or GnRH agonist analogs. It is not recommended for use in pregnant women, premenarcheal children and postmenopausal women. Consult your doctor before receiving.
Is LUGONIST 3.75MG INJECTION safe to use in children?
LUGONIST 3.75MG INJECTION is not recommended for use in premenarcheal children and adolescents (below 18 years). However, the efficacy of this medicine is expected to be the same for post pubertal adolescents (below 18 years) as for women (aged 18 years or older). Consult your doctor before receiving.
Is LUGONIST 3.75MG INJECTION safe to use in elderly patients?
LUGONIST 3.75MG INJECTION is not recommended for use in postmenopausal women. Menopause is natural cessation of menstrual cycles that marks the end of reproductive life in females. Consult your doctor before receiving this medicine.
Is LUGONIST 3.75MG INJECTION safe to use in pregnant women?
LUGONIST 3.75MG INJECTION is not recommended for use during pregnancy as it may increase the risk of pregnancy complications such as early pregnancy loss and foetal harm. Consult your doctor before receiving.
Is LUGONIST 3.75MG INJECTION safe to use in breastfeeding women?
LUGONIST 3.75MG INJECTION should be used with caution breastfeeding women only if considered necessary because it is not known whether it can pass through milk. Consult your doctor before receiving.
Article Information
Written By
DETAILSWritten By Dr. Janet.C, Pharm.D
Medical Content Writer
Last Updated
22 Mar 2023