LOSAR CH 6.25 Tablet 10's
Key Information
Generic Name
Generic Name Chlorthalidone 6.25 mg+Losartan 50 mg
Manufacturer
Torrent Pharmaceuticals Ltd
Variant
10 Tablet(s) in a Strip
Country of Origin
India
Detailed Information
Introduction
LOSAR CH 6.25 TABLET is a combination of Chlorthalidone and Losartan which belongs to the group of medicines called Antihypertensive drugs. It is used in adults to manage mild to moderate high blood pressure which is not adequately controlled by monotherapy. High blood pressure (also known as hypertension) is a medical condition in which the force of the blood exerted against the walls of the artery remains very high and as a result it may lead to severe damage to the blood vessels supplying several organs, thus causing heart attack, heart or kidney failure, stroke or even blindness. During the course of the management, your doctor might regularly monitor your blood pressure, kidney function and electrolyte balance to avoid any untoward
Uses
OF LOSAR CH 6.25 TABLET Manage mild to moderate high blood pressure in adults
How It Works
LOSAR CH 6.25 TABLET effectively reduces elevated blood pressure where losartan acts by blocking the actions of Angiotensin – II (a substance that causes narrowing of blood vessels and increase in blood pressure) at the angiotensin type-I receptors of the vascular smooth muscle and chlorthalidone acts by increasing the urinary excretion of sodium and water by inhibiting sodium-chloride reabsorption in the kidneys, thus leading to a marked decrease in blood pressure.
Directions for Use
Take LOSAR CH 6.25 TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration of LOSAR CH 6.25 TABLET for you depending upon your age, body weight and disease condition. Do not stop taking LOSAR CH 6.25 TABLET unless your doctor advises you to stop.
Side Effects
taking LOSAR CH 6.25 TABLET are dizziness, loss of appetite, upset stomach, weakness and extreme tiredness. Consult your doctor if any of the side effects worsen. USES OF LOSAR CH 6.25 TABLET Manage mild to moderate high blood pressure in adults HOW LOSAR CH 6.25 TABLET WORKSLOSAR CH 6.25 TABLET effectively reduces elevated blood pressure where losartan acts by blocking the actions of Angiotensin – II (a substance that causes narrowing of blood vessels and increase in blood pressure) at the angiotensin type-I receptors of the vascular smooth muscle and chlorthalidone acts by increasing the urinary excretion of sodium and water by inhibiting sodium-chloride reabsorption in the kidneys, thus leading to a marked decrease in blood pressure. DIRECTIONS FOR USETake LOSAR CH 6.25 TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration of LOSAR CH 6.25 TABLET for you depending upon your age, body weight and disease condition. Do not stop taking LOSAR CH 6.25 TABLET unless your doctor advises you to stop. SIDE EFFECTS OF LOSAR CH 6.25 TABLETCOMMON nettle rash, skin rash low blood pressure dizziness loss of appetite, upset stomach impotence in men UNCOMMON gout (causing pain and swelling in the joints) sleepiness, sleep disorders headache throbbing heartbeat severe chest pain shortness of breath stomach pain, severe constipation, diarrhea, nausea, vomiting hives, itching, localized swelling (edema) cough RARE yellowing of the skin or eyes due to liver or blood problems (jaundice) increased skin sensitivity to sunlight numbness or tingling sensation breathing problems allergy painless swelling under the skin brain stroke Stop taking LOSAR CH 6.25 TABLET and consult your doctor immediately if you experience any of the following side effects: severe allergic reaction (signs include rash, itching, swelling of the face, lips, mouth or throat that may cause trouble swallowing or breathing) muscle weakness or abnormal heartbeat
Warnings & Precautions
& PRECAUTIONSPREGNANCYLOSAR CH 6.25 TABLET is not recommended in early pregnancy and if you are more than 3 months pregnant, as it may seriously harm your baby if used at that stage. Consult your doctor before taking LOSAR CH 6.25 TABLET. BREASTFEEDINGLOSAR CH 6.25 TABLET is not recommended for use in breastfeeding women. Consult your doctor before taking LOSAR CH 6.25 TABLET. DRIVING AND USING MACHINESDo not drive or use any machines if you feel dizzy after taking LOSAR CH 6.25 TABLET. KIDNEYLOSAR CH 6.25 TABLET is not recommended for use in patients with severe kidney problems, kidney stones or if you are not passing any urine at all. It should be used with caution in patients with narrowing or blockage of the blood vessels leading to kidneys or if you have recently received a kidney transplant. Consult your doctor before taking LOSAR CH 6.25 TABLET. LIVERLOSAR CH 6.25 TABLET is not recommended for use in patients with severe liver impairment. It should be used with caution in patients with impaired liver function. Consult your doctor before taking LOSAR CH 6.25 TABLET. ALLERGYDo not take LOSAR CH 6.25 TABLET if you are allergic to Chlorthalidone, Losartan or sulphonamides such as sulfamethoxazole. HEART DISEASELOSAR CH 6.25 TABLET should be used with caution in patients with heart failure with or without concomitant severe life-threatening irregular heartbeat, problems with your heart valves or heart muscle, coronary heart disease, and cerebrovascular disease (caused by a reduced blood flow in the brain). Consult your doctor before taking LOSAR CH 6.25 TABLET. OTHERSLOSAR CH 6.25 TABLET is not recommended for use if you: have low blood potassium levels (signs include muscle weakness, muscle twitching, abnormal heartbeat) have low blood sodium levels (signs include tiredness, confusion, muscle twitching, fits, coma) have high blood calcium levels (signs include loss of appetite, tiredness, muscle and weakness) ever had gout have Addison’s disease (your adrenal gland does not produce enough steroids) have diabetes (high blood sugar) and managed with a blood pressure-lowering medicine containing aliskiren Before taking LOSAR CH 6.25 TABLET, inform your doctor if you: have a history of angioedema (face, lips, throat or tongue swelling) have excessive vomiting or diarrhoea or under dietary salt restriction leading to an extreme loss of fluid or salt from your body have primary hyperaldosteronism (increased secretion of the hormone aldosterone by the adrenal gland) have high cholesterol levels Use in pediatrics: LOSAR CH 6.25 TABLET is not recommended for use in children (under 6 years of age or younger) and those having kidney or liver problems. Your child’s doctor may adjust the dose depending on the child’s age and body weight. Consult your child’s doctor for advice. Use in geriatrics: LOSAR CH 6.25 TABLET should be used with caution in elderly patients. Your doctor may initiate the management with the lowest effective dose. Consult your doctor before taking LOSAR CH 6.25 TABLET.
Drug Interactions
SA. Drug - Drug interactions: Before taking LOSAR CH 6.25 TABLET, inform your doctor if you are taking any of the following medicines: medicines used to manage heart problems like high blood pressure, chest pain or irregular heartbeat (Ex. lisinopril, propranolol, methyldopa, nitroglycerin, amlodipine, guanethidine, digoxin, aliskiren, furosemide) adrenocorticotropic hormone (used to manage ulcerative colitis, Crohn's disease and rheumatoid arthritis) medicines used to manage allergic and inflammatory diseases and immune reactions (Ex. prednisolone, betamethasone) medicines used to manage stomach cramps (Ex. atropine, hyoscine) medicines used to manage cancer (Ex. cyclophosphamide, methotrexate) cholestyramine (used to reduce blood fat levels) medicines used to manage asthma (Ex. salbutamol, formoterol) amantadine (used to manage Parkinson’s disease) amphotericin (used to manage fungal infections) allopurinol (used to manage gout) carbenoxolone (used to manage ulcers) medicines used for replacement therapy (calcium salts, vitamin D) medicines used to manage high blood sugar levels (Ex. insulin, chlorpropamide, glibenclamide) medicines used to relieve pain or rheumatism (Ex. aspirin, indomethacin) ciclosporin (used after a transplant to manage organ rejection) lithium (used to manage mental illness) medicines used to make you insensitive or pain (Ex. lignocaine, midazolam) Overdosage: If you or anyone else accidentally take too much of LOSAR CH 6.25 TABLET, contact your doctor immediately or visit the nearby hospital. Overdosage symptoms of LOSAR CH 6.25 TABLET includes dizziness, nausea, vomiting, sleepiness, volume depletion, low blood pressure, electrolyte disturbances associated with irregular heartbeat and muscle spasms. SYNOPSIS Drug : Chlorthalidone, Losartan Pharmacological Category : Thiazide diuretic, Angiotensin receptor-2 blocker Therapeutic Indication : Hypertension Dosage Forms : Tablet MORE INFORMATION Keep LOSAR CH 6.25 TABLET out of reach of children Store LOSAR CH 6.25 TABLET at room temperature
Article Information
Written By
DETAILS Written By Dr. R. Dinesh John Rajkumar
Medical Content Writer
Reviewed By
Dr. Sankara Babu Gorle
Medical Expert
Last Updated
15 Dec 2022