Lorsaid Injection 2ml
Key Information
Generic Name
Generic Name Lornoxicam 8 mg
Manufacturer
Abbott Healthcare Pvt Ltd
Country of Origin
India
Detailed Information
Introduction
INTRODUCTION ABOUT LORSAID INJECTIONLORSAID INJECTION contains Lornoxicam which belongs to the group of medicines called Non-steroidal anti-inflammatory drugs (NSAIDs). It is used for short term relief of acute mild to moderate pain when oral administration is not appropriate. LORSAID INJECTION is not recommended for use in patients with severe kidney or liver impairment, severe heart failure, low blood platelet count (which increases risk of bleeding or bruising), gastro-intestinal bleeding, cerebrovascular bleeding or other bleeding disorders, history of gastrointestinal bleeding or perforation (related to previous therapy with non-steroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen) and varicella (chickenpox) infection. Before receiving LORSAID INJECTION inform your doctor if you have impaired kidney function, history of high blood pressure or heart failure, ulcerative colitis or crohn’s disease, peripheral artery or cerebrovascular disease, history of bleeding tendency or asthma, systemic lupus erythematosus (rare immunological disease) or mixed connective tissue disorders and may be at increased risk of developing diabetes or high cholesterol. Your doctor may recommend you to take relevant tests to understand your existing condition. LORSAID INJECTION is not recommended for use during the last 3 months of pregnancy and in first and second trimester of pregnancy it should be used only if clearly advised by the doctor and it is not recommended for use in breastfeeding women. LORSAID INJECTION is not recommended for use in children and adolescents (less than 18 years of age). LORSAID INJECTION should be used with caution in elderly patients (aged 65 years and above), especially in patients with impaired liver or kidney function. The common
Uses
OF LORSAID INJECTION For short-term relief of acute mild to moderate pain
How It Works
LORSAID INJECTION has an anti-inflammatory and analgesic activity that works by managing the release of chemical messengers by inhibiting an enzyme called cyclooxygenase and also inhibits the prostaglandin synthesis that results in relieving pain and swelling associated with various conditions.
Directions for Use
LORSAID INJECTION will be given to you only by a doctor or a nurse into a vein as an intravenous injection or into your muscles as an intramuscular injection. Your doctor will decide the dose, duration and frequency of LORSAID INJECTION therapy for you depending on your age, body weight and severity of the condition.
Side Effects
receiving LORSAID INJECTION are dizziness, nausea, vomiting, stomach pain, indigestion and diarrhea. Inform your doctor immediately if any of the side effect worsens or persist for a long period of time. USES OF LORSAID INJECTION For short-term relief of acute mild to moderate pain HOW LORSAID INJECTION WORKSLORSAID INJECTION has an anti-inflammatory and analgesic activity that works by managing the release of chemical messengers by inhibiting an enzyme called cyclooxygenase and also inhibits the prostaglandin synthesis that results in relieving pain and swelling associated with various conditions. DIRECTIONS FOR USELORSAID INJECTION will be given to you only by a doctor or a nurse into a vein as an intravenous injection or into your muscles as an intramuscular injection. Your doctor will decide the dose, duration and frequency of LORSAID INJECTION therapy for you depending on your age, body weight and severity of the condition. SIDE EFFECTS OF LORSAID INJECTIONCOMMON nausea, vomiting diarrhea stomach pain indigestion mild and transient headache, dizziness UNCOMMON weight changes anorexia (eating disorder) inability to sleep irritation or inflammation of the conjunctiva vertigo (head spinning sensation), ringing sensation in the ears (tinnitus) palpitations (sensation of pounding hearbeat), increased heart rate heart failure, edema (fluid retention) constipation, flatulence, belching, gastritis flushing stuffy nose facial edema, general feeling of discomfort skin rash, itching, excessive sweating, redness, hives and angioedema (painless swelling under skin) dry mouth, mouth ulcers peptic or duodenal ulcer upper stomach pain hair loss joint pain RARE sore throat anemia allergic reaction weakness confusion, nervousness or agitation feeling sleepy, tingling sensation abnormal taste sensation tremor, migraine visual disturbances hot flush, bleeding or collection of blood outside the blood vessel shortness of breath, cough, bronchospasm (lungs airway tighten) difficulty swallowing, swollen tongue or oesophagus perforated peptic ulcer vomiting of blood, gastrointestinal bleeding, black or red-coloured stools stomach acid reflux skin eczema, dermatitis, rash of purple spots bone pain, muscle pain or spasm, weakness urination at nighttime (nocturia), urinary disorders Inform your doctor immediately if you experience any of the following side effects while receiving LORSAID INJECTION: difficulty in breathing, chest pain, appearance of ankle swelling or it get worse severe continuous stomach pain or black colored stool or abdominal bleeding signs of liver problems (such as yellowish discoloration of the skin or white part of the eyes (jaundice)) allergic reaction (signs include ulcer or blistering or swelling of the face, lips, tongue or throat which may cause difficulty in breathing) fever, blistering eruption in the skin or swelling of hands and feet or in the mouth area (stevens-johnson syndrome) severe skin infection in case of varicella (chickenpox) skin reactions (signs include skin rash, damage to the internal lining of the nostrils, mouth, eyelids, ears, genitals or anus)
Warnings & Precautions
& PRECAUTIONSPREGNANCYLORSAID INJECTION is not recommended for use in the third trimester of pregnancy. It should be used with caution during the first and second trimester of pregnancy, unless considered clearly necessary. Consult your doctor before receiving LORSAID INJECTION. BREASTFEEDINGLORSAID INJECTION is not recommended for use in breastfeeding women. Consult your doctor before receiving LORSAID INJECTION. DRIVING AND USING MACHINESDo not drive or use machines after receiving LORSAID INJECTION if you experience sleepiness or dizziness. Consult your doctor for advice. KIDNEYLORSAID INJECTION is not recommended for use in patients with severe kidney impairment. It should be used with caution in patients with mild to moderate kidney impairment and your doctor may adjust the dose depending upon your kidney function. Consult your doctor before receiving LORSAID INJECTION. LIVERLORSAID INJECTION is not recommended for use in patients with severe liver impairment. It should be used with caution in patients with moderate liver impairment (Ex. liver cirrhosis) and your doctor may adjust the dose. Consult your doctor before receiving LORSAID INJECTION. ALLERGYDo not receive LORSAID INJECTION if you are allergic to Lornoxicam or other non-steroidal anti-inflammatory drugs (NSAIDs) such as aspirin or any other ingredients of this medicine. LUNGSLORSAID INJECTION should be used with caution in patients with history of asthma. Consult your doctor before receiving LORSAID INJECTION. HEART DISEASELORSAID INJECTION is not recommended for use in patients with severe heart failure. It should be used with caution in patients with a history of high blood pressure or heart failure, ischemic heart disease, peripheral arterial disease and cerebrovascular disease. Consult your doctor before receiving LORSAID INJECTION. OTHERSLORSAID INJECTION is not recommended for use if you: have low blood platelet count (which increases the risk of bleeding or bruising) have gastro-intestinal bleeding, cerebrovascular bleeding or other bleeding disorders have a history of gastrointestinal bleeding or perforation (related to previous therapy with non-steroidal anti-inflammatory drugs (NSAIDs)) have active or history of recurrent stomach ulcer/hemorrhage (two or more episodes of proven ulceration or bleeding) varicella (chickenpox) infection Before receiving LORSAID INJECTION, inform your physician if you: have ulcerative colitis or crohn’s disease have blood coagulation disorders or increased bleeding tendency have diabetes or cholesterol are a smoker have systemic lupus erythematosus or mixed connective tissue disorders Use in pediatrics: LORSAID INJECTION is not recommended for use in children and adolescents (less than 18 years of age) due to lack of safety and effectiveness. Consult your child’s doctor for advice. Use in geriatrics: LORSAID INJECTION should be used with caution in elderly patients (aged 65 years and above) especially in patients with impaired kidney or liver function and due to increased risk of gastrointestinal adverse effects. Consult your doctor before receiving LORSAID INJECTION.
Drug Interactions
SA. Drug-Drug interactions: Before receiving LORSAID INJECTION, inform your doctor if you are taking any of the following medicines: warfarin, phenprocoumon or heparin (used to manage or manage blood clots) cimetidine (used to manage heartburn and stomach ulcer) methotrexate, pemetrexed (used to manage cancer) selective serotonin reuptake inhibitors (SSRIs) Ex. fluoxetine, fluvoxamine, paroxetine, sertraline or lithium (used to manage depression) tacrolimus, cyclosporin (used to decrease the action of the immune system to manage organ rejection) rifampicin, quinolone antibiotics such as moxifloxacin, ciprofloxacin, gemifloxacin, ciprofloxacin (used to manage bacterial infection) sulphonylureas such as glibenclamide (used to manage diabetes) digoxin (used to manage heart disease) corticosteroids such as prednisolone, methylprednisolone, dexamethasone (used to manage the inflammatory condition) diuretics such as furosemide, chlorthalidone, spironolactone, beta-blockers (Ex. metoprolol, atenolol), angiotensin II receptor blockers (ARBs) (Ex. telmisartan, losartan) and angiotensin-converting enzyme (ACE) inhibitors such as captopril, lisinopril (used to lower blood pressure) anti-platelets (Ex. clopidogrel, ticlopidine) medicines used to manage heart attack and stroke other non-steroidal anti-inflammatory drugs (NSAIDs) (Ex. aspirin, ibuprofen) (used to manage pain and inflammation) Overdosage: LORSAID INJECTION will be administered to you only by a doctor or a nurse in a hospital, and so it is unlikely to receive an overdose. However, consult your doctor if you experience any unusual symptoms such as include nausea, vomiting, dizziness or impaired vision, impaired coordination ascending to coma and cramps, liver and kidney damages or coagulation disorders. SYNOPSIS Drug : Lornoxicam Pharmacological Category : Non-steroidal anti-inflammatory drugs Therapeutic Indication : Manages acute mild to moderate pain Dosage Forms : Tablet, Injection MORE INFORMATION Store LORSAID INJECTION at room temperature
Article Information
Written By
ity (HPRA). [Revised in February 2015] [Accessed on 28th June 2022] http://www.hpra.ie/img/uploaded/swedocuments/LicenseSPC_PA1547-005-003_11032015142107.pdf USEFUL DIAGNOSTIC TESTS Liver function test Kidney function test Bleeding/clotting time AUTHOR DETAILS Written By Dr. R. Dinesh John Rajkumar
Medical Content Writer
Reviewed By
Dr. Sankara Babu Gorle
Medical Expert
Last Updated
25 Nov 2022