Leucorin 15mg Tablet 10'S
Key Information
Generic Name
Generic Name Leucovorin Calcium 15 mg Also Known As: Folinate Calcium, Folinic Acid
Manufacturer
Samarth Life Sciences Pvt Ltd
Variant
10 Tablet(s) in a Strip
Country of Origin
India
Detailed Information
Introduction
LEUCORIN 15MG TABLET contains Leucovorin Calcium, which belongs to the group of medicines called Folic acid analogs. LEUCORIN 15MG TABLET is used to increase folic acid levels in the body, whereas methotrexate (medicine) lowers folic acid levels in the body. It is therefore used to counteract this and support the maintenance of folic acid levels. This is known as Leucovorin rescue. This medicine is also used to manage a form of anaemia (megaloblastic) which results from low levels of folic acid. Your doctor may advise to do routine blood tests to evaluate and monitor your health condition. LEUCORIN 15MG TABLET is generally not recommended for use in patients with pernicious anaemia or other megaloblastic anaemia caused by vitamin B12 deficiency. LEUCORIN 15MG TABLET should be used with caution in pregnant and breastfeeding women. LEUCORIN 15MG TABLET is generally safe medicine to use with no common
Uses
OF LEUCORIN 15MG TABLETIt is used: to increase folic acid levels in the body, whereas methotrexate (medicine) lowers folic acid levels in the body. It is therefore used to counteract this and support the maintenance of folic acid levels to manage a form of anaemia (megaloblastic) which results from low levels of folic acid
How It Works
Leucovorin Calcium is an active metabolite of folic acid and an essential coenzyme for nucleic acid synthesis. It can be used to selectively rescue cells from the adverse effects of methotrexate. Methotrexate inhibits nucleic acid synthesis by blocking the activation of folic acid. Leucovorin is folic acid in its active (reduced) form, so it allows nucleic acid synthesis to proceed even in the presence of methotrexate.
Directions for Use
Take LEUCORIN 15MG TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Depending on your age, body weight, and disease condition. Your doctor will determine the appropriate dose and duration for you.
Side Effects
LEUCORIN 15MG TABLETIt is used: to increase folic acid levels in the body, whereas methotrexate (medicine) lowers folic acid levels in the body. It is therefore used to counteract this and support the maintenance of folic acid levels to manage a form of anaemia (megaloblastic) which results from low levels of folic acid HOW LEUCORIN 15MG TABLET WORKSLeucovorin Calcium is an active metabolite of folic acid and an essential coenzyme for nucleic acid synthesis. It can be used to selectively rescue cells from the adverse effects of methotrexate. Methotrexate inhibits nucleic acid synthesis by blocking the activation of folic acid. Leucovorin is folic acid in its active (reduced) form, so it allows nucleic acid synthesis to proceed even in the presence of methotrexate. DIRECTIONS FOR USETake LEUCORIN 15MG TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Depending on your age, body weight, and disease condition. Your doctor will determine the appropriate dose and duration for you. SIDE EFFECTS OF LEUCORIN 15MG TABLETUNCOMMON urticaria dermatitis Stop taking LEUCORIN 15MG TABLET and contact your physician immediately if you experience any of the following side effects: serious allergic reactions such as swelling of the face, eyelids, and lips, causing sudden wheezing, difficulty in breathing, rash or itching particularly those that cover your entire body
Warnings & Precautions
& PRECAUTIONSPREGNANCYMonitoring requiredLEUCORIN 15MG TABLET should be used with caution during pregnancy only if clearly needed, as it is not known whether it may cause harm to the unborn baby. Contact your doctor before taking LEUCORIN 15MG TABLET. BREASTFEEDINGUse with CautionLEUCORIN 15MG TABLET should be used with caution in breastfeeding women. It is not known whether the medicine is excreted through breast milk. Contact your doctor before taking LEUCORIN 15MG TABLET. DRIVING AND USING MACHINESUse with CautionLEUCORIN 15MG TABLET does not affect your ability to drive or operate a machine. ALLERGYContraindicatedDo not take LEUCORIN 15MG TABLET if you are allergic (hypersensitive) to Leucovorin calcium or have an intolerance to lactose or other ingredients in this medicine. OTHERSLEUCORIN 15MG TABLET is not recommended if you have: pernicious anaemia or other megaloblastic anaemia caused by vitamin B12 deficiency
Drug Interactions
SA. Drug-Drug interactions: Tell your doctor if you have recently taken any other medicines, including medicines obtained without a prescription, vitamin supplements, herbal products or the following: antibiotics (used to manage bacterial infections) ex. chloramphenicol, trimethoprim-sulfamethoxazole antiepileptics (used to manage epilepsy) ex. phenobarbital, phenytoin, or primidone fluorouracil (used for cancer) Overdosage: If you or anyone else have accidentally taken too much of LEUCORIN 15MG TABLET, consult your doctor immediately or visit the nearby hospital. Contact your physician if you experience any unusual symptoms. SYNOPSIS Drug : Leucovorin Calcium Pharmacological Category : Folic acid analogs Therapeutic Indication : Used to increase folic acid levels with methotrexate combination Dosage Forms : Injection, Tablet MORE INFORMATION Keep LEUCORIN 15MG TABLET out of the sight and reach from children Store LEUCORIN 15MG TABLET below 25°C
Frequently Asked Questions
Common questions and answers about Leucorin 15mg Tablet 10'S.
What is LEUCORIN 15MG TABLET used for?
LEUCORIN 15MG TABLET is used to increase folic acid levels in the body, whereas methotrexate (medicine) lowers folic acid levels in the body. It is therefore used to counteract this and support the maintenance of folic acid levels. This is known as Leucovorin rescue. This medicine is also used to manage a form of anaemia (megaloblastic) which results from low levels of folic acid.
Can I take LEUCORIN 15MG TABLET to manage folic acid deficiency caused by other medicines?
LEUCORIN 15MG TABLET is an active form of folic acid. It can be used to manage methotrexate's harmful effects (which reduce folic acid levels). LEUCORIN 15MG TABLET increases folic acid levels. It is used to reverse this and help to maintain folic acid levels.
Can I take LEUCORIN 15MG TABLET while breastfeeding?
LEUCORIN 15MG TABLET should be used with caution by breastfeeding women. It is not known whether the medicine is excreted through breast milk. Contact your doctor before taking LEUCORIN 15MG TABLET.
When LEUCORIN 15MG TABLET is not recommended?
LEUCORIN 15MG TABLET is generally not recommended for use in patients with pernicious anaemia or other megaloblastic anaemia caused by vitamin B12 deficiency.
Is LEUCORIN 15MG TABLET a chemo drug?
LEUCORIN 15MG TABLET is not a chemotherapy medication, but it is given in conjunction with chemotherapy medications such as fluorouracil (5-FU) to enhance the effects of fluorouracil and to make the medicine work better.
Can LEUCORIN 15MG TABLET cause serious side effects?
LEUCORIN 15MG TABLET may cause serious side effects such as swelling of the face, eyelids, and lips, causing sudden wheezing, difficulty in breathing, and rash or itching over the entire body. Stop taking LEUCORIN 15MG TABLET and contact your physician immediately if you experience the following effects.
Should LEUCORIN 15MG TABLET be taken with food?
Take LEUCORIN 15MG TABLET with or without food, as advised by your physician. Depending on your age, body weight, and disease state, your doctor will determine the appropriate dose and duration for you.
Article Information
Written By
DETAILS Written By Dr. Janet.C
Medical Content Writer
Reviewed By
Dr. Sankara Babu Gorle
Medical Expert
Last Updated
24 Feb 2024